LOCUS       XM_022662089            3616 bp    mRNA    linear   VRT 21-JUL-2022
DEFINITION  PREDICTED: Astyanax mexicanus NRDE-2, necessary for RNA
            interference, domain containing (nrde2), mRNA.
ACCESSION   XM_022662089
VERSION     XM_022662089.2
DBLINK      BioProject: PRJNA853366
KEYWORDS    RefSeq.
SOURCE      Astyanax mexicanus (Mexican tetra)
  ORGANISM  Astyanax mexicanus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Characiformes; Characoidei; Characidae; Astyanax.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_064421) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jul 21, 2022 this sequence version replaced XM_022662089.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: Astyanax mexicanus Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3616
                     /organism="Astyanax mexicanus"
                     /mol_type="mRNA"
                     /isolate="ESR-SI-001"
                     /db_xref="taxon:7994"
                     /chromosome="14"
                     /sex="female"
                     /tissue_type="muscle"
                     /dev_stage="adult"
     gene            1..3616
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 EST, 4 Proteins"
                     /db_xref="GeneID:111188410"
     CDS             82..3504
                     /gene="nrde2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_022517810.2"
                     /db_xref="GeneID:111188410"
                     /translation="

MALFPAFSGAPDSQRAQGTELEWLNNQSFRADAAQSVHQRAAEKDTTTSSPASPQRAEEQEDGRSVGSKRKKKKEKKKKRKKQKKRSRGGSDGSGSDTVYPSDLLTQPEPPITERVECVSEGKFVWLDDLQNLSDPPFCIDRRSDPNNWQYKSLYRADIARYRRRGGAVLGLDGRTQAVLWDDAPQDKKRVERKPERYFHSSIQQLLRSEPITALPTAPPTDPADSAPFLPLPPCPELQDVPARAGGTQVDPLGVYDPGTALYLEGRGRPKTEEPRPGGADSAALLTARTEEFNRNLRQNPTHIQLWLDFIRFQDEVSGGCGAALGAVPGAEGDGERGRLTVRALLERKLAIVERALEVNPGSMELKLVKLALCQELWDPPALLKEWKKLVFLHPNSSTLWRRFLLFTQTHFSSFSTSRVSAAYAKCLSTLSAVQDGTMLSHPPLPGTEEELLEIFLLQCHFLRQAGQSEKALSLFQALLDFTFYKPDTVTHLNTRQQVEFFEPFWDSGEPRVGERGGRGWRAWMLQQERGGWVVPPETEDDDDDDEDQDECEIRDKSEPKWRIWLDVETSREAKHWLPWRPDKSKGQSEEDCEDPDRQVLFDDIGPSLIRVESASLKLRLLLAFLRFLGLPDPSAPPPSSTLLDDSALLDLSLDSERPLTSCHLPLTGISAVGHMTHLSDVRKHVGLCKEGEEFLGNVLERVLPLVRAPDRTVLSLCWLQYEKLKVLRCVYSSSSKRLRVAVRRGKRVGKRLLKLPENRSSLSLWREYAHLQWIVGNVEEGRRVFDTALAVGGASGLQDHTLCELCLLYAQLEVEQACMGGAKASVAPPTGSRAVYVLSRLAEGGGYSGFSGQVSPVSVLKARKAYENALSAAAEGGTPRSALIGCFGLFQYLTVGIDAADAVFTEARERLTPGTATATATGTEPDPSLREREAVCVLHVALLRLHSSTSAFPLSRLRMALTDALRLLPCSATLWHFYLLTESRYHSAGRARRFFHTVARGNQTIIPHLFSITAEQRRKQHLDSVIRLGLPADALPVIPETGLSNRIRSLFEVAVATEEGAHCPLLWRMYMNFMVCNGDTERGRGIFYKALQNVPWAKCVYMDAVRLFPDRVQEFLDLLVEKELRLRAPMEEVEILLEE"

     misc_feature    490..780
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(490..516,523..528,538..543,547..549,553..597,
                     604..612,616..624,646..654,664..669,673..678,685..705,
                     724..735,754..780)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    955..1926
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:429988"
     polyA_site      3616
                     /gene="nrde2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

aaggcgcttcaggggcgtcatcagagcgcgccggtgtgtgtgtgtgtgtgtgtgttagccggttagcttagctgcaacaggatggcgttatttcccgcgttttccggagcaccggattctcagcgcgcgcagggaacagaactggaatggctgaataatcagagtttccgggccgacgccgctcagagtgtgcaccagcgcgccgccgagaaggacacaaccacttccagccctgccagtccacagagagctgaggagcaggaggacgggcggagcgtcggatcaaagaggaagaagaagaaagagaagaagaagaaaaggaaaaagcagaagaagcgcagcagaggcgggtcggacggttccggctcggacacggtttaccccagtgacctgctgacccaaccagaaccaccaatcactgagagggtggagtgtgtatctgaggggaagttcgtgtggttggatgatctgcagaacctcagtgatccaccgttctgtatcgaccggagatccgacccaaacaactggcaatacaaatccctgtaccgagcagatatcgccaggtacaggcggaggggcggagctgtgctgggattggacggtaggactcaggccgtgttgtgggatgacgcccctcaggataagaagcgagtggagaggaaaccggagcgctacttccactcctccatacagcagctgctccgctctgagccaatcacagccctccctacagctcctcccactgaccccgcggactccgcccccttcctccccttgcccccctgccctgagctccaggatgtccccgctcgggcgggcgggacccaggtggaccccctgggcgtgtacgacccaggcaccgccctgtatctggagggaaggggccggccgaagaccgaggagccgcgcccgggcggagccgacagcgcagccctgctgaccgcccgcaccgaggagttcaaccggaacctccgccagaaccccacccacatccagctgtggcttgacttcatccgcttccaggatgaggtctcgggcggatgcggcgcggcgctgggtgcagtgccgggtgcggagggtgacggggagcgcggcaggttgacggtgcgagcgctgctggagaggaagctagcgatcgtggagcgggcgctggaggtgaaccccggcagcatggagctgaagctggtgaagctggcgctgtgccaggagctgtgggacccccccgcactgctgaaggagtggaagaagctggtgttcctccacccgaacagctccaccctgtggaggagattcctgctcttcacccagacccacttcagctccttctccacctccagggtcagcgccgcctacgccaagtgtctgagcacgctcagtgcggtgcaggacggcaccatgctctcccacccaccactgccgggcacagaggaggagctactggaaatcttcctcctgcagtgtcacttcctgcggcaggccggccaatcagagaaagcgctcagcctgtttcaggccctgctggactttaccttctacaaacccgacactgtcactcaccttaacacccgacaacaggtggagtttttcgagccgttctgggacagcggtgagccgcgggtgggtgagcgaggggggcggggctggagggcgtggatgctccagcaggagagaggaggatgggtggtgccacctgagacagaggatgatgatgatgatgatgaagatcaggacgagtgtgagatcagagataagtctgagccgaagtggaggatctggttggatgtggaaacgtctcgtgaagcgaagcactggttgccctggagacctgacaaaagcaagggccaatcagaggaggactgtgaggatccagacagacaggtgctgttcgatgacatcggcccgtccctgatccgggtggagtctgcgagcctgaagctccgccttcttctcgccttcctacggtttctgggcttaccggacccctcggccccgccccccagcagcacactcctggatgactccgccctgctggacctcagcctggactcagagcgacctctgacctcctgccacctccctctgaccgggatcagcgctgtgggtcacatgacacacctgagtgatgtcaggaagcatgtggggctatgtaaggagggggaggagtttctggggaacgttctggaacgggtcctgccactggtcagggcgccggacagaactgtcctgtcgctctgctggctgcagtacgagaagctgaaggtgttgcggtgtgtgtacagcagcagcagtaagcggttgcgggttgcggtgcggcgcgggaagcgggtggggaaacggttactgaagctgccggagaaccgcagcagcctcagcctgtggcgggagtacgctcacctgcagtggattgtgggtaatgtggaggaggggcggagagtgttcgacacggcactcgcagtgggaggggcttcaggactgcaggaccacaccctctgcgaactctgccttttgtacgcccagttagaggtggagcaggcgtgcatgggcggagctaaagcctccgtggctccgcccactggctctcgggctgtctatgttctgagcaggctggcggaggggggcgggtacagcgggttctcagggcaggtgagcccggtgtcggttctaaaggcccggaaagcgtacgagaacgccctatcagcagctgcagagggcgggacaccacggagtgctctgattggctgtttcggactgttccagtacctgacggtggggattgacgctgctgatgcggtcttcactgaagccagagagcggctgacacccggcactgccactgccactgccactggcacagaacccgacccgtcactcagagagcgcgaggccgtgtgcgtcctgcatgtggcactgctgcggctgcactccagcaccagcgccttccccctgtcccgcctccggatggcgctgaccgacgccctgcgcctcctgccctgcagcgccaccctgtggcacttctacctgctgaccgagagccgttaccatagcgccggccgcgcccgcaggttcttccacaccgtcgccaggggcaaccagaccatcataccacacctgttctccatcaccgcagagcagcggaggaaacaacacctcgactccgtcatcaggttgggtcttccagccgatgctctgccagtgatcccggagacgggccttagtaaccgtatccgctcactgtttgaggttgccgtggcgacggaggagggagcccactgccccctgctgtggaggatgtacatgaactttatggtgtgtaacggggacacagagagaggaagaggaatcttctataaagctctacagaacgtcccctgggctaaatgtgtgtatatggacgcggtgcggttgtttccggatcgggttcaggagtttttggatctgctggtggagaaggagctccggctccgagcgccgatggaggaggtggagatcctgctggaggaataaacgcctacactacccacaatgcaccagacctgcggaccctcacatacctttatttatattttatttggatatgaaaatggtaattttgtgataaatgtatatatttatagtc

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