2024-03-28 17:38:43, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NM_205249 1332 bp mRNA linear VRT 23-SEP-2023 DEFINITION Gallus gallus homeobox D12 (HOXD12), mRNA. ACCESSION NM_205249 VERSION NM_205249.2 KEYWORDS RefSeq. SOURCE Gallus gallus (chicken) ORGANISM Gallus gallus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus. REFERENCE 1 (bases 1 to 1332) AUTHORS Tang H, Finn RD and Thomas PD. TITLE TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations JOURNAL Bioinformatics 35 (3), 518-520 (2019) PUBMED 30032202 REFERENCE 2 (bases 1 to 1332) AUTHORS Kamiyama N, Seki R, Yokoyama H and Tamura K. TITLE Heterochronically early decline of Hox expression prior to cartilage formation in the avian hindlimb zeugopod JOURNAL Dev Growth Differ 54 (6), 619-632 (2012) PUBMED 22708793 REMARK GeneRIF: Expression of Hoxd11/Hoxd12 in the chick hindlimb decreased and disappeared from the presumptive zeugopod region before cartilage formation. REFERENCE 3 (bases 1 to 1332) AUTHORS Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C, Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S. TITLE Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation JOURNAL Database (Oxford) 2012, bar068 (2012) PUBMED 22301074 REMARK Publication Status: Online-Only REFERENCE 4 (bases 1 to 1332) AUTHORS Kataoka K, Yoshitomo-Nakagawa K, Shioda S and Nishizawa M. TITLE A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities JOURNAL J Biol Chem 276 (1), 819-826 (2001) PUBMED 11036080 REFERENCE 5 (bases 1 to 1332) AUTHORS Mackem S and Mahon KA. TITLE Ghox 4.7: a chick homeobox gene expressed primarily in limb buds with limb-type differences in expression JOURNAL Development 112 (3), 791-806 (1991) PUBMED 1682126 REFERENCE 6 (bases 1 to 1332) AUTHORS Izpisua-Belmonte JC, Tickle C, Dolle P, Wolpert L and Duboule D. TITLE Expression of the homeobox Hox-4 genes and the specification of position in chick wing development JOURNAL Nature 350 (6319), 585-589 (1991) PUBMED 1673231 REFERENCE 7 (bases 1 to 1332) AUTHORS Nohno T, Noji S, Koyama E, Ohyama K, Myokai F, Kuroiwa A, Saito T and Taniguchi S. TITLE Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development JOURNAL Cell 64 (6), 1197-1205 (1991) PUBMED 1672266 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JAENSK010000236.1. On Sep 23, 2021 this sequence version replaced NM_205249.1. ##Evidence-Data-START## Transcript exon combination :: X62019.1, HAEL01007512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103992604, SAMEA3109051 [ECO:0000348] ##Evidence-Data-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-569 JAENSK010000236.1 8580089-8580657 c 570-1332 JAENSK010000236.1 8579055-8579817 c FEATURES Location/Qualifiers source 1..1332 /organism="Gallus gallus" /mol_type="mRNA" /db_xref="taxon:9031" /chromosome="7" /map="7" gene 1..1332 /gene="HOXD12" /note="homeobox D12" /db_xref="CGNC:7046" /db_xref="GeneID:396178" exon 1..569 /gene="HOXD12" /inference="alignment:Splign:2.1.0" CDS 8..808 /gene="HOXD12" /note="Ghox 4.7; homeo box D12; chox-4F; chox-4.7; ghox-4.7; homeobox protein Hox-4F; homeobox protein Hox-4.7; Hox D12" /codon_start=1 /product="homeobox protein Hox-D12" /protein_id="NP_990580.1" /db_xref="CGNC:7046" /db_xref="GeneID:396178" /translation="
MCDRSLYRSGYVGSLLNLQSPDSFYFPNLRANGSQLAALPTISYPRSSIPWTCPSPCAAQPQGHAFGGAAQPYLPGSVPISISSNSNKECLEENSKYYAHDASSKQEERCRQRQSFANDPTITHAANLKPAKYDHSSLPRSLHGSAALFEVNSCTSSLKEDIKNSVNLNLTVQPAAVQSCLRPSVQDGLPWCPTQGRSRKKRKPYTKQQIAELENEFLLNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVMREQALSMY"
misc_feature order(602..616,620..622,671..673,689..691,728..730, 734..739,746..751,755..763,767..772) /gene="HOXD12" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:238039" misc_feature 608..769 /gene="HOXD12" /note="Homeobox domain; Region: Homeobox; pfam00046" /db_xref="CDD:425441" misc_feature order(608..610,617..619,737..739,746..751,758..760) /gene="HOXD12" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:238039" exon 570..1332 /gene="HOXD12" /inference="alignment:Splign:2.1.0" ORIGIN
gttggaaatgtgtgatcgcagtctctacagatctggctacgttggttctctcttgaacttgcaatctccagattccttttattttcccaatttgcgggctaatggcagtcagttggcggctctgcccaccatttcctacccccggagctcgatcccgtggacgtgccccagtccgtgcgcagctcagccgcagggccacgcgttcggcggcgcggcgcagccgtacctccccggctccgttccaatcagcatcagctccaacagcaacaaagagtgcctggaagaaaacagtaaatattacgcccacgacgcgagctccaaacaagaggaaagatgcaggcagaggcaatctttcgcaaatgacccaactattactcacgcagccaacttaaagcccgcaaagtatgaccactcgagcctgccgaggagcttgcacggctcggccgctctttttgaagtgaattcctgcacttccagcctaaaggaggacatcaagaattcggtcaacttgaacctgacagttcagcccgcggcagtccagtcatgcctcagaccttcagtgcaggatggtttgccttggtgccccacccaggggagatcgcgaaagaaacggaaaccgtacacaaaacagcaaatcgccgaattggaaaacgagtttctcctcaatgagtttattaaccgacagaagaggaaagaactatcaaacagactgaatttaagcgaccagcaagtgaaaatttggtttcagaaccgacgaatgaaaaagaaaagagtggtaatgcgcgagcaggcgctctctatgtactagcgcggcgcccgcccgttcccgcatgaacttgcgttcgccccgtagagtagcgtgtggtcgcggctgcgaggcgggagctgggtgggttttcccctttaagccgagctctcggaacgcgtaggatccccgcgtgcgtcggcaaccgctgagctcttaggcagagcgaagaagacgagccagcccagcactgaaacccgtattatcagcttttccccctttctttctccttttatatagatcttctccctcttctaaccccctctttccccggagaacgtgcggcgctaaactaaaatcgatgcctttttaactgtatgtaaacaccactttgcaggaaaaaaaaaaaaaaaaaagaataaaagaataatgcctagtaaagacgtctgtaaatgccggctggtcccttcatgtgttccccgcttctgaaggcgagcatgcggcgctcgcgtgttttgtggtttggaataacctgttggagcacagatcgcacaaagcggttaccaaataaacctttttagttttca
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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