LOCUS       NM_001096633            1465 bp    mRNA    linear   VRT 20-NOV-2021
DEFINITION  Xenopus laevis engrailed homeobox 1 L homeolog (en1.L), mRNA.
ACCESSION   NM_001096633
VERSION     NM_001096633.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC106393.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC106393.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00012418, SAMD00012419
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="9_10L"
                     /map="9_10L"
     gene            1..1465
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="engrailed homeobox 1 L homeolog"
                     /db_xref="GeneID:735177"
                     /db_xref="Xenbase:XB-GENE-6254268"
     exon            1..584
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    104..106
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="upstream in-frame stop codon"
     CDS             215..904
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="engrailed 1; En-1a homeobox protein; Homeobox
                     protein en-1-A"
                     /codon_start=1
                     /product="homeobox protein engrailed-1-A"
                     /protein_id="NP_001090102.1"
                     /db_xref="GeneID:735177"
                     /db_xref="Xenbase:XB-GENE-6254268"
                     /translation="

MEDQTDQSPGAPSEPDPGASPPPLHPVLPTHRTTNFFIDNILRPDFGCRKETPGRGNSSPLHTRPGNPAPSPDSDTPSDSSKGSDSNPALLLVGNAAPPVHKKDSVVWPAWVYCTRYSDRPSSGPRTRKLKKKKSEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQSLAQELSLNESQIKIWFQNKRAKIKKASGMKNGLALHLMAQGLYNHSTTTVQEKEQESE"

     misc_feature    order(635..646,650..652,701..703,719..721,758..760,
                     764..769,776..781,785..793,797..802)
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    638..799
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(638..640,647..649,767..769,776..781,788..790)
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    803..895
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /note="Engrailed homeobox C-terminal signature domain;
                     Region: Engrail_1_C_sig; pfam10525"
                     /db_xref="CDD:431338"
     exon            585..1438
                     /gene="en1.L"
                     /gene_synonym="en-1; En-1A; en1-a; en1-b; en1a; eng1;
                     engrailed-1; xen1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gttccagtctgtctctctgtactgagtgtcccatttcgggtgctgtttggtggggtctagaccagaggttgcaggtttaagtgtgagggttgcaggctacagttaggggaccaggcgcttcattagagggttgggggctacttactttgctgctgcagccccacgcagtgcagggcccctagagaaggtggtcccggggctggagggcgataacatggaggatcaaactgatcaaagccccggggccccaagtgagccagatccaggggcctcacctccccctctgcaccctgtgctccccactcaccggaccactaacttcttcatagacaacattctccggccggactttggctgcaggaaagagacccccgggaggggcaactccagccccctgcacacccgcccgggcaaccctgctccgagcccagactctgacaccccatcagacagttccaagggcagcgactccaacccggctctgctcctggtgggcaacgcggcgccccctgtgcacaagaaagactctgtggtgtggcccgcctgggtctattgcactcgctactccgaccgaccctcctctggccctaggacccgcaagctaaaaaagaagaagagcgagaaggaagacaagaggccccgaacagccttcactgctgagcagctccagagactgaaggctgagttccaagccaaccgctacatcacagagcagaggagacagagcttggcccaagagctgagcctcaatgaatcccaaataaagatctggttccagaacaaaagggccaagatcaaaaaggcatcggggatgaagaatggcctggctctccatctcatggctcagggactgtacaaccactccactactactgtgcaggagaaggagcaggagagtgagtgaaggggcagcacccccagtgactatgccaatgttctactactactgtgcaggacaatgagcaacaggggtaactctgccaagtgactctgaagctgtcgttccgctactgggcaggagagtgagtaaatgggacagcctagtctggtgccagtactatttgttattgtgcagcacagactttgggaaaattcacccagcaacagggaaatctcctgctcttgttgtcccattgtggtgcccaatgaaatccccccattatatggatacaacgaactccctcagagtatggacccaacagatgtaccttttgctgtatggaccccagtgttcccccttatcaattccagggtttttgactgttccccatttgactgcagaaccagtttctgggcaccccacaaatggaggtgttgaactgtcctttcaagccaaagattttctgctgttggagttgtgtaaccttaataaagagtgcgttgtgcccggacccgactgcccgtaacttatttgctaataaatcctgaggcaatcacaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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