LOCUS       XM_005158556            4249 bp    mRNA    linear   VRT 15-JUN-2017
DEFINITION  PREDICTED: Danio rerio NRDE-2, necessary for RNA interference,
            domain containing (nrde2), mRNA.
ACCESSION   XM_005158556
VERSION     XM_005158556.4
DBLINK      BioProject: PRJNA13922
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_007128.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jun 15, 2017 this sequence version replaced XM_005158556.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Danio rerio Annotation Release 106
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4249
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="17"
     gene            1..4249
                     /gene="nrde2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 EST, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 36 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:794348"
                     /db_xref="ZFIN:ZDB-GENE-111117-3"
     CDS             64..3531
                     /gene="nrde2"
                     /codon_start=1
                     /product="protein NRDE2 homolog"
                     /protein_id="XP_005158613.1"
                     /db_xref="GeneID:794348"
                     /db_xref="ZFIN:ZDB-GENE-111117-3"
                     /translation="

MALFPSFSGLSGSNSSAESKAPADLEWLSNQSFSTEDALKTHQRATDRARAETEEPAGTSEEKHKERGDNHGKSKKRKKEKKKKHKKKRSRDNSESSGFESDTIYPSDLLKKENTDREEAQVRVSETFMWLDDLQTPTDSPFCIDRRADRANWQYKSLYRGDIARYKRKGGSCLGLDLRTQAVTWTDGGPEKKRVDKKAERYFSSSTRQLLQTRGLLALPILSEGSATNSDPYIKLAVCAEEQGSSTQTPESWVNPLGIYDPGTTLWLEGKGQPEVKGEQQSTEAQESNSTLLSARVEEFNRNLRENPTDIKLWLDFVHFQDELAFGSGSFSSAGDCDAEMRKMSLRAVLEKKLSIMDRAVESNPSDVDLKLEKLRLCKELWEPAVLQKEWKKLVFIHPNSAPLWKKYLLFTQSHFSTFSVSKVNGVFGKCLSTLSAVQDGSMVSHPPLPGTQEDLLDIFLQQCHFLRQAGHTEKAVCLFQALLDFTFFKPDNVKNLATRQQVDFFEPFWDSGEPRIGERGARGWKAWMLQQEKGGWVIPPEPDDDEEEEQEDSEIKDKTWPKWKIWLDVEASREANQWLPWRPDKTKGQSEEDCEDPDRQVLFDDIGPSMIRVDRADLQAQLILAFLQFLGLPGALTKFFTASSSSFLLDDLTFLEEGPDPERPLTSYDLPVTGICAVGHMTCLSGCRRQAGLCKAGEEFLHNVLHQTLRLVPAQDQAAITLCWLQYEKLKVLRCLRSGNKRQMKSQGKRSKRLAKRLLKEPENRGSLALWREYAHLEWLLGNLEEARKVFDTALSMGVSRGLNDHVLCKLCFLYAQLEVEQALSSETVSTFSKAVYILTKLAEGASYTPFSGQINPVVILKARKAYEQALLSILPEQNTDSNAGASKKHNRTSSLIGCFGLFQYLTMGIDAAQAVYSQAIQKLIPSHFNSEAAEGSRRRSTIFADCEAVAVQHVALLRHHTNTNVFPLSRLRLALTDALSLLPSSASLWHLYLQTENHYHSAGRTRRFFHSMAKKTDSVVPYLFAITAEQRLKQLLDSVQRSRLPGEALPTLPVNGLSNRIRCLFESATGTEHGAHCPLLWRMYLNFMVCDGNADRGSGIFYKALQEVPWVKGLYMDAVQLFPERVQEFLDLMTEKELRLRMPMEEVDILLEE"

     misc_feature    484..771
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(484..510,517..522,532..537,541..543,547..591,
                     598..606,610..618,640..648,658..663,667..672,679..699,
                     718..729,748..771)
                     /gene="nrde2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    958..1959
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:429988"
ORIGIN      

cctgtcaggtcgcaggtagatgacgtcattatcccgcgtctgttttgatgtattagaagcagcatggctctgttcccgtccttctctggactgtcaggcagcaacagctctgcagaaagtaaagctccagcggatctggaatggctgagtaatcagagcttcagcactgaagatgctttgaagactcaccagcgagccacagacagagcccgagcagagacagaggaaccggcaggcacaagtgaggagaagcataaagagagaggagacaaccatggaaaatcgaagaaaagaaagaaagaaaaaaagaaaaaacacaaaaagaagaggagcagagataactctgaaagtagtgggttcgaatcagacaccatatatcccagtgaccttctaaaaaaggagaacactgacagagaggaagctcaagttcgggtgagcgagacctttatgtggctggatgacctccagacccccactgactcccccttctgcatcgacaggagagctgaccgtgccaactggcaatacaaatccctttataggggagacatagccaggtataaaaggaagggaggctcgtgtctagggttggacttgagaacgcaggctgtgacctggactgatggaggaccagagaagaagcgagtggacaagaaagcagaacgctatttctcttcttccacccgtcagctgcttcaaacaaggggtctgctagctttgcctatactctctgaaggcagcgccaccaactctgatccctatataaaacttgcagtctgtgctgaagaacagggctcttctacccaaacacctgaatcatgggtcaatccgctgggcatttatgatcctggaaccaccttgtggctggagggcaagggccagccggaggtcaagggagaacaacagagcactgaggcccaagagagcaacagcactcttctgagcgctcgagtggaggagtttaacaggaacctacgggagaatcctacagacatcaagctgtggttggactttgtacactttcaggatgagctggccttcggttctgggtctttctcttctgccggtgactgtgatgcagaaatgaggaagatgtctctacgtgctgtgctggagaagaagctctccatcatggacagagcagtggaaagtaacccttctgacgttgacctgaaattagaaaaactccgtctgtgcaaggagttatgggagcctgccgtcctgcagaaagagtggaagaaactagtgttcattcatccaaacagcgcacctttatggaagaagtatctgctcttcacacagagccatttcagcaccttctcagtgtctaaggtcaatggagttttcggcaagtgtctgagcacgcttagtgcagtccaggatggcagcatggtgtctcaccctccacttccaggcacacaggaagacctcttggatatctttctgcagcagtgccatttcctgcgtcaggcaggtcatacagagaaagctgtttgcctttttcaagccctactggacttcactttcttcaagccagacaatgtaaagaatctggccaccagacaacaggtggatttttttgagccattttgggacagtggagagcccaggattggggagcggggggctcgcggatggaaggcttggatgcttcaacaggagaaaggaggatgggtgattccacctgagccagatgatgacgaagaggaagagcaggaggactctgagatcaaagacaaaacttggcctaagtggaagatctggttagatgtggaggcgtcccgagaggcaaaccaatggctgccatggagaccagataaaaccaagggccaatcagaagaggactgcgaggacccagacagacaggtcttatttgatgatattggcccatccatgattcgtgttgacagagcagatctccaggcgcagctaattctggcattcctgcagttcctcggtctccccggagctctaaccaagttctttacagcatcttcttctagctttctgctggacgatctcaccttccttgaagagggccctgatccggagcgaccactgacctcttatgacctcccagtgactgggatctgtgctgtgggtcacatgacatgtcttagtggatgcaggaggcaagcagggctgtgtaaagctggagaggagtttcttcacaatgttttgcatcaaactctccgactggtccctgcacaggatcaagctgctattactctgtgctggctgcagtacgagaaactcaaggtgctgaggtgtttacgaagtggaaataaaagacaaatgaagtctcaggggaagcgcagtaaacgtcttgcaaaaaggctgctaaaggagccagagaacaggggcagtctggcactttggagagaatatgcccatctggagtggcttctaggaaatctggaagaggctcgaaaagtttttgacactgctttgagtatgggtgtttctaggggtcttaatgaccatgttctctgcaagctctgctttctttacgcccagctagaggtagaacaggctttaagcagtgaaacagtttctacattctccaaagctgtctacattctgactaaattagcagaaggtgcttcctacactcctttctctggccagatcaacccagtggtcatattgaaggccagaaaggcctatgagcaggccctgttgagtattttacccgaacagaacacagacagcaatgctggagcttcaaagaaacacaataggacgtccagtctaattggatgttttggactttttcagtacctaacaatggggatcgatgcagcacaagctgtgtacagtcaggccatccaaaaactcattcccagccatttcaattcagaagcagcagagggatctcggagaagatccacgatctttgcggactgtgaggctgttgctgtccagcatgtagcactgctgcgccatcacactaacactaatgtgttccccctatcccgactgagactggcacttacagatgcgctctccttactgccctccagtgcctcattatggcatctctacctgcaaacagagaaccactaccacagcgcaggccgaactcgcaggttctttcacagcatggcaaagaaaactgacagtgttgtgccgtatctcttcgccatcactgcagaacaacgtcttaaacagttgctggactctgtgcaaaggtctcgtcttcctggtgaagctcttcccaccctgccagtgaatggtcttagcaatcgtatccgttgtctgtttgaaagcgctacaggaacagagcatggagcccactgtcctctgctgtggagaatgtatctgaacttcatggtgtgtgatgggaatgcagacagaggcagtggaatcttttacaaggctttacaggaagtgccctgggtaaagggcttgtacatggatgcagtgcagctgtttcctgaacgtgtgcaggagtttttagacctcatgactgagaaggagttgcgtctgagaatgcccatggaggaggtggacatcctgctggaggagtagccatcaaacccttcccgtaatacaccagaatcaacaaccgctgttcattagccaacagaaacagaatctctctcaacaaacagtaaaaaaaataattaattacagattttatttatttttatccatttctaaatgtattttttgtaattttgagattaaataatgtttcatttaatatgttcctggtcttttttaaaaatgaaagattgtgagaatttatcatggtttggtttgtagtaggttttagctatctgaatgacctgactggtttgacatttggaacaatttagtatgatagttaacctagtaatgaaacttctgccatgcaatgaaacttatttactcacccttgacttgttccaaaccaattagattttttttcatatgttgaacatgaaagaagatattttgaagaatgctggaaacctgtaactgttgaaataaaaatctttcttttgtgaaaatgatagaattttcagtttatgagtaaactacccctttagagccagctgtaatcttaataggctacattttggccagcagagggcatccatgctctcttaatgctgtccgggatttgacccacaaatttaaaactgcagattaggattattttaaaacaccaagaggttgttgcagtgctttagactggagcttagactctgtgtcgcctccatgctgaatgttctgctacgcaaaataaataaataaaaaatca

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