2024-11-01 08:35:38, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_200656 2915 bp mRNA linear VRT 29-JUL-2024 DEFINITION Danio rerio guanylate cyclase activator 1Ab.1 (guca1ab.1), mRNA. ACCESSION NM_200656 XM_697225 VERSION NM_200656.1 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. REFERENCE 1 (bases 1 to 2915) AUTHORS Cudia,D.L., Ahoulou,E.O., Bej,A., Janssen,A.N., Scholten,A., Koch,K.W. and Ames,J.B. TITLE NMR Structure of Retinal Guanylate Cyclase Activating Protein 5 (GCAP5) with R22A Mutation That Abolishes Dimerization and Enhances Cyclase Activation JOURNAL Biochemistry 63 (10), 1246-1256 (2024) PUBMED 38662574 REMARK GeneRIF: NMR Structure of Retinal Guanylate Cyclase Activating Protein 5 (GCAP5) with R22A Mutation That Abolishes Dimerization and Enhances Cyclase Activation. REFERENCE 2 (bases 1 to 2915) AUTHORS Cudia,D., Roseman,G.P., Assafa,T.E., Shahu,M.K., Scholten,A., Menke-Sell,S.K., Yamada,H., Koch,K.W., Milhauser,G. and Ames,J.B. TITLE NMR and EPR-DEER Structure of a Dimeric Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors JOURNAL Biochemistry 60 (41), 3058-3070 (2021) PUBMED 34609135 REFERENCE 3 (bases 1 to 2915) AUTHORS Ogawa,Y. and Corbo,J.C. TITLE Partitioning of gene expression among zebrafish photoreceptor subtypes JOURNAL Sci Rep 11 (1), 17340 (2021) PUBMED 34462505 REMARK Publication Status: Online-Only REFERENCE 4 (bases 1 to 2915) AUTHORS Ames,J.B. TITLE Structural Insights into Retinal Guanylate Cyclase Activator Proteins (GCAPs) JOURNAL Int J Mol Sci 22 (16), 8731 (2021) PUBMED 34445435 REMARK GeneRIF: Structural Insights into Retinal Guanylate Cyclase Activator Proteins (GCAPs). Review article Publication Status: Online-Only REFERENCE 5 (bases 1 to 2915) AUTHORS Lim,S., Scholten,A., Manchala,G., Cudia,D., Zlomke-Sell,S.K., Koch,K.W. and Ames,J.B. TITLE Structural Characterization of Ferrous Ion Binding to Retinal Guanylate Cyclase Activator Protein 5 from Zebrafish Photoreceptors JOURNAL Biochemistry 56 (51), 6652-6661 (2017) PUBMED 29172459 REMARK GeneRIF: these results indicate a strong Fe(2+)-induced inhibition of guanylate cyclase by GCAP5 and suggest that GCAP5 may serve as a redox sensor in visual phototransduction. REFERENCE 6 (bases 1 to 2915) AUTHORS Sulmann,S., Vocke,F., Scholten,A. and Koch,K.W. TITLE Retina specific GCAPs in zebrafish acquire functional selectivity in Ca2+-sensing by myristoylation and Mg2+-binding JOURNAL Sci Rep 5, 11228 (2015) PUBMED 26061947 REMARK Erratum:[Sci Rep. 2015 Sep 02;5:13508. doi: 10.1038/srep13508. PMID: 26329014] Publication Status: Online-Only REFERENCE 7 (bases 1 to 2915) AUTHORS Fries,R., Scholten,A., Saftel,W. and Koch,K.W. TITLE Zebrafish guanylate cyclase type 3 signaling in cone photoreceptors JOURNAL PLoS One 8 (8), e69656 (2013) PUBMED 23940527 REMARK Publication Status: Online-Only REFERENCE 8 (bases 1 to 2915) AUTHORS Scholten,A. and Koch,K.W. TITLE Differential calcium signaling by cone specific guanylate cyclase-activating proteins from the zebrafish retina JOURNAL PLoS One 6 (8), e23117 (2011) PUBMED 21829700 REFERENCE 9 (bases 1 to 2915) AUTHORS Imanishi,Y., Yang,L., Sokal,I., Filipek,S., Palczewski,K. and Baehr,W. TITLE Diversity of guanylate cyclase-activating proteins (GCAPs) in teleost fish: characterization of three novel GCAPs (GCAP4, GCAP5, GCAP7) from zebrafish (Danio rerio) and prediction of eight GCAPs (GCAP1-8) in pufferfish (Fugu rubripes) JOURNAL J Mol Evol 59 (2), 204-217 (2004) PUBMED 15486694 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC057493.1. On Jul 6, 2005 this sequence version replaced XM_697225.1. ##Evidence-Data-START## Transcript exon combination :: BC057493.1, DN856622.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..2915 /organism="Danio rerio" /mol_type="mRNA" /strain="AB" /db_xref="taxon:7955" /chromosome="22" /map="22" gene 1..2915 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /note="guanylate cyclase activator 1Ab.1" /db_xref="GeneID:393629" /db_xref="ZFIN:ZDB-GENE-040426-1577" exon 1..223 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /inference="alignment:Splign:2.1.0" CDS 26..622 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /note="guanylate cyclase activator 1e" /codon_start=1 /product="guanylate cyclase activator 1Ab.1" /protein_id="NP_956950.1" /db_xref="GeneID:393629" /db_xref="ZFIN:ZDB-GENE-040426-1577" /translation="
MGDSSSMSATELSACKCHQWYRKFMTECPSGQLTFYEFKKFFGLKNLSEKSNAYVNTMFKTFDIDDDGCIDFMEYVAALSLVLKGGVQQKLRWYFKLFDMDGSGCIDKDELLLIFKAVQAINGAEPEISAEDLADMVFNKIDVNGDGELSLEEFMEGISADEKISEMLTQSLDLTRIVSNIYNDSYIEQEAEIIEDQA"
misc_feature 113..499 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /note="Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]; Region: FRQ1; COG5126" /db_xref="CDD:444056" exon 224..373 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /inference="alignment:Splign:2.1.0" exon 374..464 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /inference="alignment:Splign:2.1.0" exon 465..2902 /gene="guca1ab.1" /gene_synonym="gcap5; guca1e; zgc:66243" /inference="alignment:Splign:2.1.0" ORIGIN
gtgcaccgtcctgacgctcctcagcatgggggactcctccagcatgtccgccaccgagctcagcgcctgcaaatgccaccagtggtaccgcaagttcatgaccgagtgtccgtccggccagctcaccttctacgagttcaagaagttcttcggcctcaagaatctgtccgagaaatcgaacgcatacgtcaataccatgttcaagaccttcgacattgacgacgatggctgtattgatttcatggagtatgtggcagctctgagtctggtcctgaaaggcggtgttcagcagaagctgcgctggtatttcaagctcttcgatatggacggcagcggctgtatcgacaaggacgaactgctgctcatcttcaaggcggttcaagccattaatggagccgagccggagatctctgcagaggacttggctgatatggtgtttaacaagattgatgttaatggagacggcgagttgtctctggaagagttcatggagggcatctcggcggatgagaagatctcagagatgctgacccagagtttggatctgacccggatcgtgagcaacatctacaacgactcctacatcgagcaggaggccgagatcatcgaggatcaagcatgacaacactgagagtctggagcggacgcttttattggctccttcccagagtagcgagtgccgagtgtaaaacatagatcggccaaagctctgggtctgtgcactagattatatcatctgaacgcacaaaatgctccagtactgtgagtgtgtagttcagcctgagggtggcgctctaacactgacacacaggctgtaagtacacaccacacatgcgtagaacgcttctagaaatgccttaatgtagagtttaatgcctctgaatgctgatttagagttttgaacaagcgtaggaaatcttggtcgcactttattttaatgtacaattcacgctaacaacaaaccattcactaagaatatagctcaatacactactgattagctgcttaataatagttagtaggttagtagttgggtattgggttggattagagatgtaggatatgatcaaacatgctaatatctcctaataatgctaagccagtcataaatgctgtgaattgttacttaaacttagtgttactaaatacttatttgcattatatgtgagcatatgtaaagatgtatatatttttattaatctactacgttgttaaggaagtagcaattactgaagaagatgacgaatcgagtcagagcggtttacgaggtaatgtgaagaaagcagagcagtctgcagttccgtttttcgccaccgatttacactgtagttttatgggggcgctgttgagctcagtgcttagcctcacttaaagggccagttcacccaaaaatgataatattctcatcatttcttcactctttacaggtttaaacctgtttaactttatttattctgttaaactcaaaggaacatatactgaaaaagctggaaacctttaaccattgacattcatagtattttatttcggttttcctactactaagtgcttttcactttcctcaaaaaacaaaactgaagaaagaaactcacacattttttaaacaaaatcacagcagttttctgaacatatgaaccgaattttccaatatatatttcttttattgcttaaatcaggggtgcccaaacttcttcgtatgaagggccaaaaaccgaatatcattgagagtcgcgggctgaagatggccattgggaatttcctaatttatttcagaatatttcaaaataaatagaaaacattacataaaatcatattaaataatgctggataacattttaaatgataaattatttcaataaaaacaatcagatttataacagggctgctgcagtgaatcgattaaattgataaaaatcgattactaaaagcgttggcaatgaatttcataatcgatttgttgtgtcgcgtgacacgggtatggttgattattaaaaagcacttcagttgaaaggagttcaacagcaggagcctacttttgttctgttttgaagtgagggccgtaaagtccctggtgctgatgtttcactcgttatccagcttgtcaagcatgacaagttagcattaactcatttacttttagagcggaaataaaaaaaatgaacctgagtttggcgcggtgtctggcgctgggcagagctctcagtaagggaccgtctgaaaagtgcttctttatttttttttttcccccaaaaacaaaaccaacttaaccccgctgagaaagacgtgtcatattatcacaattatgcagcgttttaaccgcctaatgcttattttatgttttagacatgtaaactcacagacttactagtaaaacaaaacatttagagtttgtaaaacacacaaggaagtctaacaatccattcaaatataatttgctgatgtgatttattcatatcagatacacattacacatagtgaacgtaactttaaagctgaatctactcttctctaaggtcaccagccacttacttgcatgtgtttaggcggtaactggtgaatttaccgccgtattctgcttttatgaatgaggagaactggtatgtgaactggtaaaacttctgcttttgtcttttcggttagaaattaatgctttttttattcgattcatcgaaaaaaaatctagattaatcaattataaaaataatgattagttgcagccctaatttataacacagcggagttcagtgctgaatacactagtcaagcagaatctgcctttgacttaatttgctcaccaaactctctgcattgtcgggtgacggtatttgcatttaaactaaatctgatttacttacaccatttaattgacactggtaatttcagctagcttttaacaataaaaaaaaaaaaaaaaa
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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