LOCUS       NM_131772               2472 bp    mRNA    linear   VRT 28-JUL-2023
DEFINITION  Danio rerio claudin 11b (cldn11b), mRNA.
ACCESSION   NM_131772
VERSION     NM_131772.3
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2472)
  AUTHORS   Solis CJ, Hamilton MK, Caruffo M, Garcia-Lopez JP, Navarrete P,
            Guillemin K and Feijoo CG.
  TITLE     Intestinal Inflammation Induced by Soybean Meal Ingestion Increases
            Intestinal Permeability and Neutrophil Turnover Independently of
            Microbiota in Zebrafish
  JOURNAL   Front Immunol 11, 1330 (2020)
   PUBMED   32793187
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2472)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2472)
  AUTHORS   Shu Y, Lou Q, Dai Z, Dai X, He J, Hu W and Yin Z.
  TITLE     The basal function of teleost prolactin as a key regulator on ion
            uptake identified with zebrafish knockout models
  JOURNAL   Sci Rep 6, 18597 (2016)
   PUBMED   26726070
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2472)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2472)
  AUTHORS   McKee R, Gerlach GF, Jou J, Cheng CN and Wingert RA.
  TITLE     Temporal and spatial expression of tight junction genes during
            zebrafish pronephros development
  JOURNAL   Gene Expr Patterns 16 (2), 104-113 (2014)
   PUBMED   25460834
REFERENCE   6  (bases 1 to 2472)
  AUTHORS   Baltzegar DA, Reading BJ, Brune ES and Borski RJ.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
REFERENCE   7  (bases 1 to 2472)
  AUTHORS   Kumai Y, Bahubeshi A, Steele S and Perry SF.
  TITLE     Strategies for maintaining Na balance in zebrafish (Danio rerio)
            during prolonged exposure to acidic water
  JOURNAL   Comp Biochem Physiol A Mol Integr Physiol 160 (1), 52-62 (2011)
   PUBMED   21600298
REFERENCE   8  (bases 1 to 2472)
  AUTHORS   Clelland ES and Kelly SP.
  TITLE     Tight junction proteins in zebrafish ovarian follicles: stage
            specific mRNA abundance and response to 17beta-estradiol, human
            chorionic gonadotropin, and maturation inducing hormone
  JOURNAL   Gen Comp Endocrinol 168 (3), 388-400 (2010)
   PUBMED   20553723
REFERENCE   9  (bases 1 to 2472)
  AUTHORS   Loh YH, Christoffels A, Brenner S, Hunziker W and Venkatesh B.
  TITLE     Extensive expansion of the claudin gene family in the teleost fish,
            Fugu rubripes
  JOURNAL   Genome Res 14 (7), 1248-1257 (2004)
   PUBMED   15197168
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR354583.8.
            
            On Jul 28, 2023 this sequence version replaced NM_131772.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC139523.1, GDQH01014036.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-364               CR354583.8         23675-24038
            365-529             CR354583.8         26301-26465
            530-2472            CR354583.8         30139-32081
FEATURES             Location/Qualifiers
     source          1..2472
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="24"
                     /map="24"
     gene            1..2472
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /note="claudin 11b"
                     /db_xref="GeneID:81592"
                     /db_xref="ZFIN:ZDB-GENE-010328-13"
     exon            1..364
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    106..108
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /note="upstream in-frame stop codon"
     CDS             139..909
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /note="claudin 11"
                     /codon_start=1
                     /product="claudin-11b"
                     /protein_id="NP_571847.2"
                     /db_xref="GeneID:81592"
                     /db_xref="ZFIN:ZDB-GENE-010328-13"
                     /translation="

MSNSCRLLCGFLMSFVGWIGIIIATSTNDWVLSCTYGSHSCRNMDDLETKGLWTECVISTALYHCIPLNQVRRIPAYIQACRVLMVSASLLGLPALALLLLAMPCVKVSQETEGTKHRRAVQGGLIILVISLCGMVSTVWFPIGKLDGLMSFGFSLYAGWVGSALCFFAGSVMVCCSKDHSPSENPESRHYYSNPDGVTSTGPSENPETRYYYSNHDGVTSSGTSENQETRFYYSNHDGVTSYGPAKNSHAKSEHV"

     misc_feature    157..648
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
     exon            365..529
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /inference="alignment:Splign:2.1.0"
     exon            530..2472
                     /gene="cldn11b"
                     /gene_synonym="cldn11; fb97c11; wu:fb97c11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atggaatgtttttacagtcctcactccaaccgttagttcagccaacaaatctcactcagaatgcgttttatttaagtcagagatcctagcacaagtttttggccttgaggagcaaataataatacgctttcagtcagaatgtctaatagctgtcgtctgctttgtggttttttgatgagttttgtcggctggattgggataataatcgcgacctccacaaatgattgggtgctgtcctgtacatacggatcgcacagctgcaggaatatggacgacctggagaccaaaggcttgtggacggagtgtgtcatctctactgctctctatcactgcatccctctcaaccaggtccgcagaataccagcttacatccaggcatgtcgtgttctgatggtgtctgcctctctgctcggtctgcctgctctggctctcttgctgctggcgatgccctgtgtcaaagtcagccaggagactgaaggcaccaaacacagacgcgcagttcagggaggactaataatactcgtcatatctctgtgtgggatggtgtcgacggtttggttccccatcggaaagctggacggcctgatgtcttttggattctctctgtatgctggctgggtgggttcagcgctctgcttttttgccggctctgtgatggtttgttgctcaaaagatcacagcccaagcgagaatcctgaatcccgccactactactcaaacccagatggagttaccagcaccggcccaagcgagaatcctgaaacccgctactactactcaaaccacgatggagttaccagctccggcacaagcgagaatcaagaaacccgtttctactactcaaaccacgatggagttaccagctatggccctgctaaaaacagccatgccaagagcgaacatgtgtgagagactcactggagaaaaaacaaaactcagctctttacctcaagatttgaacactcaaactcacacagacacataacaaagaagtatgtggagaattaattttctcccgccatggattgactgcacacatctgaagattttggagggaacacacttggcagaggtttggagtttaaagggccatgacaccccccactttcggttaaagtctacttcagaatattttcaaaagatgcatgattaatgggcgtggagctccgcaagcataaggcaggagtgggcgtggccagcaggggagaaggggagcgaacaactgttgatgtcagttagctcacaaaatgagacaaaccgtgaagagacgcatgagtttatagtttacaaagttaaaatgcaaagaaataaacagtaatttaatgccctgctacatttgttattcgtaatttcatatacagacaaccacaatttatataattataaagataatcgtgttcatataaacactataaatgaggacttctccctcaatccccggaactcctgatacaagacaacatccgccattctccaattctcgtgctgctctcccgacaaaaatgctagcagcacacacacagctttgctgtatgatcggccctgacaggatcgcggggaaaatcatgcaacaaaccccgtggatcatggaaacagacacatacgagcctttataaacggctactgcgtgcccgtgggtccgtgtctcacagcttgagcttggcactggtctggcaggtctgcgtctgccttgccttcggaaagcgcgtgctgtcatgctctcatgaataattaagcagccggctcttctcataggataaggaaactccgctttgaataataatgagaaaccgacgcatcatcattgcacttgcggtacttcgctatgtcgccgattttgatcccgccccaaaaatcattttaaacccggaagctgaaattagctgacaaaattatccagtttaccccacaattaaagctgacaggtgctaacattatcttaactgatgctcaacacacacaaatctgttaacatataaaaaaaagttctccagggtgtcctgaacctttaaaggccttgttcgaaaagacagagatgaatccaaaggaaaagacttgtgattttcctgagcatgtttatttacacagtattcattttacttgtatgttttgtttttagtgactttattttaacattacaaaaaatgttagcttattagttcatgccaacatttaggacagcttattcactcagacagacaggaagtctatgtggttaaatgagcagatgtgatctgcactgttttcctggagagcatcttgcagcatcctgcactaaacctcctaggaaatcactaaaataaaataaagcgcctggaacaggaaaactgctcatttttaatgtctcatatggttggttggtgattgatttattgtggtcgagcattattgtttgcaattttttggacatatttgagacatctccgctaatatccactttgcatttttactataaaggtgctgtaagtttta

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