LOCUS       NM_131766               1796 bp    mRNA    linear   VRT 05-JUN-2025
DEFINITION  Danio rerio claudin f (cldnf), mRNA.
ACCESSION   NM_131766
VERSION     NM_131766.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Liu,H., Leslie,E.J., Jia,Z., Smith,T., Eshete,M., Butali,A.,
            Dunnwald,M., Murray,J. and Cornell,R.A.
  TITLE     Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in
            murine oral epithelium, and dominant-negative KLF4 variants are
            present in patients with cleft lip and palate
  JOURNAL   Hum Mol Genet 25 (4), 766-776 (2016)
   PUBMED   26692521
REFERENCE   2  (bases 1 to 1796)
  AUTHORS   Shu,Y., Lou,Q., Dai,Z., Dai,X., He,J., Hu,W. and Yin,Z.
  TITLE     The basal function of teleost prolactin as a key regulator on ion
            uptake identified with zebrafish knockout models
  JOURNAL   Sci Rep 6, 18597 (2016)
   PUBMED   26726070
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1796)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1796)
  AUTHORS   Baltzegar,D.A., Reading,B.J., Brune,E.S. and Borski,R.J.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
REFERENCE   5  (bases 1 to 1796)
  AUTHORS   de la Garza,G., Schleiffarth,J.R., Dunnwald,M., Mankad,A.,
            Weirather,J.L., Bonde,G., Butcher,S., Mansour,T.A., Kousa,Y.A.,
            Fukazawa,C.F., Houston,D.W., Manak,J.R., Schutte,B.C., Wagner,D.S.
            and Cornell,R.A.
  TITLE     Interferon regulatory factor 6 promotes differentiation of the
            periderm by activating expression of Grainyhead-like 3
  JOURNAL   J Invest Dermatol 133 (1), 68-77 (2013)
   PUBMED   22931925
  REMARK    Erratum:[J Invest Dermatol. 2013 Mar;133(3):859]
REFERENCE   6  (bases 1 to 1796)
  AUTHORS   Kumai,Y., Bahubeshi,A., Steele,S. and Perry,S.F.
  TITLE     Strategies for maintaining Na balance in zebrafish (Danio rerio)
            during prolonged exposure to acidic water
  JOURNAL   Comp Biochem Physiol A Mol Integr Physiol 160 (1), 52-62 (2011)
   PUBMED   21600298
REFERENCE   7  (bases 1 to 1796)
  AUTHORS   Clelland,E.S. and Kelly,S.P.
  TITLE     Tight junction proteins in zebrafish ovarian follicles: stage
            specific mRNA abundance and response to 17beta-estradiol, human
            chorionic gonadotropin, and maturation inducing hormone
  JOURNAL   Gen Comp Endocrinol 168 (3), 388-400 (2010)
   PUBMED   20553723
REFERENCE   8  (bases 1 to 1796)
  AUTHORS   Loh,Y.H., Christoffels,A., Brenner,S., Hunziker,W. and Venkatesh,B.
  TITLE     Extensive expansion of the claudin gene family in the teleost fish,
            Fugu rubripes
  JOURNAL   Genome Res 14 (7), 1248-1257 (2004)
   PUBMED   15197168
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JBMGRA010000015.1.
            
            On Jan 6, 2017 this sequence version replaced NM_131766.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AF359424.1, SRR26395014.1366761.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1796              JBMGRA010000015.1  2697901-2699696     c
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="15"
                     /map="15"
     gene            1..1796
                     /gene="cldnf"
                     /gene_synonym="cldn28d; sr:nyz177; wu:fb13d10; zgc:109866"
                     /note="claudin f"
                     /db_xref="GeneID:81585"
                     /db_xref="ZFIN:ZDB-GENE-010328-6"
     exon            1..1796
                     /gene="cldnf"
                     /gene_synonym="cldn28d; sr:nyz177; wu:fb13d10; zgc:109866"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..709
                     /gene="cldnf"
                     /gene_synonym="cldn28d; sr:nyz177; wu:fb13d10; zgc:109866"
                     /codon_start=1
                     /product="claudin f"
                     /protein_id="NP_571841.2"
                     /db_xref="GeneID:81585"
                     /db_xref="ZFIN:ZDB-GENE-010328-6"
                     /translation="

MGRIAKEVAGQTLCFIGFVGICICCGIPMWRVTTYIGANIVTGQIVWDGLWMNCVMQSTGQMQCKIQDSIMNLTQDLQVARALVIISILIGFMGMLLTFIGGQCSSCLKNESSMAKVLILGGILCIVAGVLLLIPVCWSAAYTISDYVSVTTIQTQKRELGASIYVGWGASAFLLFGGIILCTSCPPRENIYPQYPGMYPYQGPVYGHQYAPSTVYKPYHPPVAYTPAPRQYL"

     misc_feature    26..550
                     /gene="cldnf"
                     /gene_synonym="cldn28d; sr:nyz177; wu:fb13d10; zgc:109866"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
ORIGIN      

cttcaatatgggaaggattgctaaagaagtggccggccagaccctgtgcttcatcggttttgtgggcatctgcatctgctgtggcattcccatgtggcgggtcaccacctacatcggcgccaacatcgtgacaggccagatcgtgtgggacggcctgtggatgaactgcgtgatgcagagcacgggacagatgcagtgcaaaatacaggactccatcatgaacctgacccaggatctgcaggtggcgcgcgcactggtcatcatctccatactgatcggattcatgggcatgctgctgacgtttattggtggacagtgcagtagctgcctgaagaacgagtcctccatggctaaagtgctcattctgggaggcatcctgtgcattgttgctggagtcctgcttctgattcctgtgtgctggtctgcggcgtacaccatctccgattatgttagtgtgaccaccattcagacgcaaaagagagagcttggagcgtctatatatgtcggctggggtgcttcagcgttcctgttattcggagggattattctgtgcacttcttgcccacccagagaaaatatctacccacagtacccaggcatgtacccgtaccagggaccggtgtatgggcatcagtacgctccgagtacagtttacaaaccgtatcatcctcctgttgcttatacacctgctccaaggcaatatctttaacacaaaggacggacgtcgtctaaagactactcctgaagatggaaagaattgtgttgagctgaatcaaaacaattcttgagtttttggggagacaatttaaatgttttaagctcaatcaacctcaatttgtaaagacatttaagttgacttgatcgatttgtgttgggacagcatggagggattgtgtggaactcaacacttatagcgtgtatctgtattttaaagtgataattcacccaaaaatgaagattctgtcatcatttactcactatttttgtttttatttcttgttaagcacagaaaggaaggaaactggaaacctgtaaccattgacttccattgtatttgttgtactcaatggtttcagtcagtcagcattcttcaaaatatcttcctttgtgttcaacagaaactggtaaaggtttggaaacacttgagggagaataaataaggcggtaaatgtagatttttgtgtgaactgtccctttaattcagtgtttatctgaattgaatgtatttaaaagcaattttattgaggtcttgtacttccccaagctttaaacgaagatgatctggaaaagctaaaacttgttggtcttgtttttgagattttcgcagtgctaatgaatgatgtttgtttcaacatggtcatatttgaaggtactataaagtatatttcttgactgactctctgaataaatactctaatgccattaatctgatcaaaatcaagatcacaaagactttttacttccaaaaactctttactccaacatatttctcaaggaggaacaatataaagacaatatctgttgcatattcatctgctccgtcaatatctttaactcaaaggacggacatcttctaaaactgctcctgaagatggaaagaattgtgttgagctgaatcaaaacaattcttgagtttttgaggagacaatttaattgttttaagctcaatcaacctcaatttgtaaagacatttaagttgacttgatcgatttgtgttgggacagcatgaagggattgtgcggaactcaacatttacagcgtatatctgtattttaaagtgataattcacccaaaaa

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