2024-05-06 08:56:45, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NM_131155 1760 bp mRNA linear VRT 15-MAY-2023 DEFINITION Danio rerio homeobox A10b (hoxa10b), mRNA. ACCESSION NM_131155 VERSION NM_131155.2 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. REFERENCE 1 (bases 1 to 1760) AUTHORS Banu S, Gaur N, Nair S, Ravikrishnan T, Khan S, Mani S, Bharathi S, Mandal K, Kuram NA, Vuppaladadium S, Ravi R, Murthy CLN, Quoseena M, Babu NS and Idris MM. TITLE Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach JOURNAL Genomics 114 (2), 110300 (2022) PUBMED 35134499 REFERENCE 2 (bases 1 to 1760) AUTHORS Yamada K, Maeno A, Araki S, Kikuchi M, Suzuki M, Ishizaka M, Satoh K, Akama K, Kawabe Y, Suzuki K, Kobayashi D, Hamano N and Kawamura A. TITLE An atlas of seven zebrafish hox cluster mutants provides insights into sub/neofunctionalization of vertebrate Hox clusters JOURNAL Development 148 (11) (2021) PUBMED 34096572 REFERENCE 3 (bases 1 to 1760) AUTHORS Smeeton J, Natarajan N, Naveen Kumar A, Miyashita T, Baddam P, Fabian P, Graf D and Crump JG. TITLE Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton JOURNAL Development 148 (2) (2021) PUBMED 33462117 REMARK Publication Status: Online-Only REFERENCE 4 (bases 1 to 1760) AUTHORS Messina A, Pulli K, Santini S, Acierno J, Kansakoski J, Cassatella D, Xu C, Casoni F, Malone SA, Ternier G, Conte D, Sidis Y, Tommiska J, Vaaralahti K, Dwyer A, Gothilf Y, Merlo GR, Santoni F, Niederlander NJ, Giacobini P, Raivio T and Pitteloud N. TITLE Neuron-Derived Neurotrophic Factor Is Mutated in Congenital Hypogonadotropic Hypogonadism JOURNAL Am J Hum Genet 106 (1), 58-70 (2020) PUBMED 31883645 REFERENCE 5 (bases 1 to 1760) AUTHORS Zuccarini G, D'Atri I, Cottone E, Mackie K, Shainer I, Gothilf Y, Provero P, Bovolin P and Merlo GR. TITLE Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos JOURNAL Int J Mol Sci 21 (1), 168 (2019) PUBMED 31881740 REMARK Publication Status: Online-Only REFERENCE 6 (bases 1 to 1760) AUTHORS Yekta S, Shih IH and Bartel DP. TITLE MicroRNA-directed cleavage of HOXB8 mRNA JOURNAL Science 304 (5670), 594-596 (2004) PUBMED 15105502 REFERENCE 7 (bases 1 to 1760) AUTHORS Chiu CH, Dewar K, Wagner GP, Takahashi K, Ruddle F, Ledje C, Bartsch P, Scemama JL, Stellwag E, Fried C, Prohaska SJ, Stadler PF and Amemiya CT. TITLE Bichir HoxA cluster sequence reveals surprising trends in ray-finned fish genomic evolution JOURNAL Genome Res 14 (1), 11-17 (2004) PUBMED 14707166 REFERENCE 8 (bases 1 to 1760) AUTHORS Chiu CH, Amemiya C, Dewar K, Kim CB, Ruddle FH and Wagner GP. TITLE Molecular evolution of the HoxA cluster in the three major gnathostome lineages JOURNAL Proc Natl Acad Sci U S A 99 (8), 5492-5497 (2002) PUBMED 11943847 REFERENCE 9 (bases 1 to 1760) AUTHORS Feldman B, Dougan ST, Schier AF and Talbot WS. TITLE Nodal-related signals establish mesendodermal fate and trunk neural identity in zebrafish JOURNAL Curr Biol 10 (9), 531-534 (2000) PUBMED 10801442 REFERENCE 10 (bases 1 to 1760) AUTHORS Snell EA, Scemama JL and Stellwag EJ. TITLE Genomic organization of the Hoxa4-Hoxa10 region from Morone saxatilis: implications for Hox gene evolution among vertebrates JOURNAL J Exp Zool 285 (1), 41-49 (1999) PUBMED 10327649 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR392024.15. On Apr 17, 2018 this sequence version replaced NM_131155.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GDQH01030876.1, GFIL01012784.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-864 CR392024.15 72246-73109 c 865-1760 CR392024.15 70181-71076 c FEATURES Location/Qualifiers source 1..1760 /organism="Danio rerio" /mol_type="mRNA" /strain="Tuebingen" /db_xref="taxon:7955" /chromosome="16" /map="16" gene 1..1760 /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /note="homeobox A10b" /db_xref="GeneID:30391" /db_xref="ZFIN:ZDB-GENE-990415-97" exon 1..864 /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /inference="alignment:Splign:2.1.0" misc_feature 69..71 /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /note="upstream in-frame stop codon" CDS 99..1142 /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /note="hox-A10; homeobox gene A-10; homeo box A10b" /codon_start=1 /product="homeobox protein Hox-A10b" /protein_id="NP_571230.2" /db_xref="GeneID:30391" /db_xref="ZFIN:ZDB-GENE-990415-97" /translation="
MSSRKGNLLPPSNYTTKMSCSDSPSGNSFLVDSLIHGRSEGSGHYYQNSGVYLQPTSEYSYGLSNCGYFSGLKRNESNSQNVVPTCGPYQGMETWLETSRSCRIEQPNNQITPRSFSPTIKEENSYCLYESEKCPKETITEDISYSRLTPNSCPSSNNNGCVPVPGYFRLSQTCTTSKGFTDNQTIPTHVVAQRSTRFDSSLSAIAAEASRDESDEPPTCAPCAPGRNKELRGSTGTASSPEPPDSPEKAVTVTKAGDSKSESTANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMSRENRIRELSANFSFS"
misc_feature order(918..932,936..938,987..989,1005..1007,1044..1046, 1050..1055,1062..1067,1071..1079,1083..1088) /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:238039" misc_feature 924..1085 /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /note="Homeobox domain; Region: Homeobox; pfam00046" /db_xref="CDD:425441" misc_feature order(924..926,933..935,1053..1055,1062..1067,1074..1076) /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:238039" exon 865..1760 /gene="hoxa10b" /gene_synonym="Hoxa-10; hoxa10; z-140" /inference="alignment:Splign:2.1.0" ORIGIN
ggaggagtcatcggtgctcgttgcgatttaattggctgttagctcacactgagttgtatagttatcagtaattatattcagaatgttttgcacaagaaatgtcatccagaaagggcaatcttcttccaccgtcaaattataccacaaagatgtcatgctccgatagtccatctggaaattcgtttttggtagattctttgatccacggaaggtccgagggaagtggacactactaccaaaacagcggagtttacttgcagccgacctccgaatattcttatggactgtctaactgtggctatttttcgggactcaagcggaacgagagcaactcgcaaaatgtagtacctacatgtggtccatatcaaggcatggaaacatggttggagacgtcgaggtcctgtcgcattgaacagcctaacaaccaaattaccccacggtcgttctcgcccaccataaaagaggaaaactcttactgcttatatgagtctgagaagtgcccaaaagaaaccattacagaggatatatcgtactcgcggctgacaccaaactcatgtccatctagcaacaataacggctgtgttccggtgcccggttacttccgtctgtctcagacatgcaccacatctaagggttttacagacaaccagactataccgactcatgtagtggctcaacgttcaactcgatttgacagctctctttcagctatagcagccgaagcaagccgggacgagagcgacgagccccccacatgcgcaccatgtgccccgggaagaaacaaggagctaagggggtccactggcaccgcttcatctccagaaccaccggacagcccggagaaggcggtcactgtaactaaagcaggagattccaaaagtgagagtacagctaactggctgacggcgaagagtggccgcaagaagcgttgcccttacaccaaacatcagacattagagctggagaaggagtttctcttcaacatgtacttgacacgagaacgtcgcctcgagattagccgcagtgttcacctcacagacagacaagtcaaaatatggtttcaaaaccgacggatgaagctgaagaagatgagtagagaaaaccgaatccgcgagttgtcagccaacttcagtttttcatgaagcgtctagctttatagatctctggcgccctcctccatcagctgcagtggtagtctacttgcatccaaccgtctacgtagatgtgtgcatatatgacttgtgcaagatactattgataacttattgtgtgtcgtatactgttgacgtttttatatgtttatgtataattttatttgacaacccagtcgtcataacatgtcatggttatttataaactgtcaagagcacttcactgtaaagcaagagaggaaaatatcgaatgctaaaggtgttcattgtacatagcattctgattatattgtacatttattgtatataaatgcgatatttgcatgttgtaataataactattatgaatcgatttttaaataataacgtttgtttataagtacgaccttgtcatgtatttgctgttctgggcataattggaggagtccaattctttaaaatgtagaaatgtgtataattgcagacacgacggaattcctgtattagactattaccagcatccaaatgtaccatctttctggaaatacaggccgagaagatggactcgggtgtaaaataaatatacgtgacagaaaataaataaaggcatgtacatgaaaatcatcataa
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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