2024-11-01 08:32:17, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001327784 1341 bp mRNA linear VRT 17-FEB-2024 DEFINITION Danio rerio nicotinamide riboside kinase 2 (nmrk2), transcript variant 1, mRNA. ACCESSION NM_001327784 VERSION NM_001327784.1 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. REFERENCE 1 (bases 1 to 1341) AUTHORS Horzmann,K.A., Lin,L.F., Taslakjian,B., Yuan,C. and Freeman,J.L. TITLE Anxiety-related behavior and associated brain transcriptome and epigenome alterations in adult female zebrafish exposed to atrazine during embryogenesis JOURNAL Chemosphere 308 (Pt 3), 136431 (2022) PUBMED 36126741 REFERENCE 2 (bases 1 to 1341) AUTHORS Keller,R.M., Beaver,L.M., Reardon,P.N., Prater,M.C., Truong,L., Robinson,M.M., Tanguay,R.L., Stevens,J.F. and Hord,N.G. TITLE Nitrate-induced improvements in exercise performance are coincident with exuberant changes in metabolic genes and the metabolome in zebrafish (Danio rerio) skeletal muscle JOURNAL J Appl Physiol (1985) 131 (1), 142-157 (2021) PUBMED 34043471 REFERENCE 3 (bases 1 to 1341) AUTHORS Sullivan,C., Lage,C.R., Yoder,J.A., Postlethwait,J.H. and Kim,C.H. TITLE Evolutionary divergence of the vertebrate TNFAIP8 gene family: Applying the spotted gar orthology bridge to understand ohnolog loss in teleosts JOURNAL PLoS One 12 (6), e0179517 (2017) PUBMED 28658311 REMARK Publication Status: Online-Only REFERENCE 4 (bases 1 to 1341) AUTHORS Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D., Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H., Guiguen,Y. and Bobe,J. TITLE Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database JOURNAL BMC Genomics 17, 368 (2016) PUBMED 27189481 REMARK Publication Status: Online-Only REFERENCE 5 (bases 1 to 1341) AUTHORS Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S., Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M., Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y., Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B., Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R. TITLE RFX transcription factors are essential for hearing in mice JOURNAL Nat Commun 6, 8549 (2015) PUBMED 26469318 REMARK Publication Status: Online-Only COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH432193.1, EH594583.1, CU013534.11 and EH485974.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: GFIL01028370.1, EH432193.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-214 EH432193.1 10-223 215-814 EH594583.1 217-816 815-935 CU013534.11 60296-60416 c 936-1341 EH485974.1 12-417 FEATURES Location/Qualifiers source 1..1341 /organism="Danio rerio" /mol_type="mRNA" /strain="Tuebingen" /db_xref="taxon:7955" /chromosome="2" /map="2" gene 1..1341 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /note="nicotinamide riboside kinase 2" /db_xref="GeneID:447879" /db_xref="ZFIN:ZDB-GENE-040912-44" exon 1..155 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" CDS 130..726 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /note="isoform 1 is encoded by transcript variant 1; integrin beta 1 binding protein 3" /codon_start=1 /product="nicotinamide riboside kinase 2 isoform 1" /protein_id="NP_001314713.1" /db_xref="GeneID:447879" /db_xref="ZFIN:ZDB-GENE-040912-44" /translation="
MKFIIGIGGVTNGGKTTLTGRLIKNLPNCCVVHQDDFFKPQDQIELGEDGFRQWDVITALDMDAMVNTVKGWMENPVKFARSHGVSVSTTSDPDSDIHILIVEGFLLYNYKPLIDVYNKCFYVTIPYEECKRRRSTRTYTVPDPPGLFDGHVWPMYLKHRTEMENSSLDIQYLDGMSSKDELYNQLYEDIQNSLLNIL"
misc_feature 139..630 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /note="Nicotinamide riboside kinase (NRK) is an enzyme involved in the metabolism of nicotinamide adenine dinucleotide (NAD+). This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR) to form nicotinamide mononucleotide (NMN). It defines the NR...; Region: NRK1; cd02024" /db_xref="CDD:238982" misc_feature order(154..156,169..180) /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /note="active site" /db_xref="CDD:238982" exon 156..246 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" exon 247..295 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" exon 296..461 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" exon 462..533 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" exon 534..640 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" exon 641..726 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" exon 727..1326 /gene="nmrk2" /gene_synonym="itgb1bp3; zgc:103408" /inference="alignment:Splign:2.1.0" ORIGIN
aatgaaatagtaaaaagagggagattctgggagaaaggaaaggagagagaggctgaaagcattcccaaggaagcgattcctttgctagtgtcctatcgcgaagaccaagaacaaacaaagaggatcagaatgaagtttattattggaatagggggtgtgaccaatggaggaaagacaactttgactggaagactcataaagaacctaccaaactgttgtgtggttcatcaagatgattttttcaagccccaagatcaaatagagctcggggaggacggctttagacaatgggatgtcattaccgccttagacatggacgccatggtgaacactgttaaaggatggatggagaacccggtgaagtttgcacgatcccatggcgtgagcgtttccaccacatctgaccctgatagtgacatccacatactcattgtggagggatttctgctttataactacaagcctttaattgacgtctataacaagtgcttctacgtcaccattccatatgaagagtgcaaaaggagaagaagtacgagaacgtacaccgttcctgacccacccggtctgtttgacggccatgtttggccaatgtacttgaaacacaggacagaaatggagaacagcagcttggatatccaatatctggacggcatgagctctaaggacgagctctataaccaactttatgaagacattcagaactctctgttgaacatcttatagcatctccaatcggattgaagatgtgtttgtgtatagaactgtaaataggatcttaagtagattcggcttctgccactggatgaactttgtaaatacgatgaagtactaacttatttgaaaacttgtggctagtgcctttgattttatattgctctgtgtaacttttgttttatttaaaatcacgcctcactctctgggctgatcagagatgtacagttttcatgtatactgtaattgaagaacttcaatcaaaacacacatttgaactctttatctgttgtgttttcattcttagcattgagacgtgcatgcatttaaaccatcttgtgcatgtttatggattatgatgaaggaatataataaaaatataaaataaataacacataactcaagaaataaatatgaatgtattgggcaagatataacatatatacattttaattaaaacatttcacagagtttaagtaaatactgtaaaattccagggcttttaatgtaaagattgttcatttacatgaaaatgcattagatattatgtatgcgctttcattctcagcattaaaacatgcatgttattttaaaaaacatgcaaatatttccaaaaaaaaaaaaaaa
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]