2024-11-01 08:14:16, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001302232 3075 bp mRNA linear VRT 01-JUL-2018 DEFINITION Danio rerio protein argonaute-3 (LOC567622), mRNA. ACCESSION NM_001302232 XM_009292706 VERSION NM_001302232.1 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JX448393.1. On Oct 7, 2014 this sequence version replaced XM_009292706.1. ##Evidence-Data-START## Transcript exon combination :: JX448393.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..3075 /organism="Danio rerio" /mol_type="mRNA" /strain="AB" /db_xref="taxon:7955" /chromosome="16" /map="16" gene 1..3075 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="protein argonaute-3" /db_xref="GeneID:567622" exon 1..245 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" misc_feature 224..226 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="upstream in-frame stop codon" CDS 227..2830 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /EC_number="3.1.26.n2" /note="eukaryotic translation initiation factor 2C, 1; argonaute 3a" /codon_start=1 /product="protein argonaute-3" /protein_id="NP_001289161.1" /db_xref="GeneID:567622" /translation="
MEIGTTGAVGAQSLFSMPRRPGYGTMGKPIKLLANCFQVEIPKMDVYLYEVDIKPEKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKKSLYTANPLPVAPAGVDLDVTLPGEGGKDRPFKVSIKFVSLVSWHLLHEVLTGRSMPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYEADPSVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRVSTEHFMNRTVATPSHGVWDMRGKRFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEVIQDLSSMVRELLIQFYKSTRYKPTRTIFYRDGVSEGQFRQVLYYELLAIREACISLEKEYQPGITYIVVQKRHHTRLFCADRSERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEFQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTLRTMYFA"
misc_feature 443..727 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 755..907 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 908..1270 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(1064..1066,1109..1111,1151..1153,1163..1165, 1217..1219,1238..1240,1244..1246) /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1403..2701 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1835..1837,1847..1849,1883..1894,1901..1903, 1925..1927,1934..1936,1946..1948,1958..1960) /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(2039..2041,2045..2047,2255..2257,2669..2671) /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /note="active site" /db_xref="CDD:240015" exon 246..417 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 418..538 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 539..747 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 748..884 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 885..1019 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1020..1107 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1108..1255 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1256..1375 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1376..1519 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1520..1653 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1654..1838 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1839..1998 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 1999..2089 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 2090..2284 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 2285..2419 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 2420..2521 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 2522..2721 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" exon 2722..3075 /gene="LOC567622" /gene_synonym="ago3a; eif2c1" /inference="alignment:Splign:2.1.0" ORIGIN
caatctgtcaaccgtacccgaaatcccgaccggatagtttgagtcacataccgggcaaccaaacattatctccggtgacacacgagcctcagggaaggtggactaataccgagaggaatcgcttgcggtgggttaacgcaaccggtttgtgcggccataggacagtcagagtttctgaagttcatcaactgcgagccggggacggaaccggacagagacctcatgaatggaaatcggaactacaggagccgttggggcccagtccctgttctccatgccacggaggcccggctatggcaccatggggaaacctatcaaactgctggccaactgcttccaggtggagatcccaaagatggacgtctacctgtacgaggtggacatcaagcccgagaagtgtccacggagagtaaatagggaggtggtggactccatggtgcagcactttaaagtcaccatctttggggatcgaaggccagtttatgatgggaagaaaagtctctacaccgccaacccacttcctgtggcacctgcaggggtggatctggatgtcacgctgccaggtgaagggggcaaagaccggccctttaaagtctcaattaagtttgtgtctctggtgagctggcacctgctgcacgaggtgctaaccgggcgcagtatgccagagccgctggaactggacaagccaatcagcaccaacccagtgcacgctgtggatgtggtgctccgccatctgccctccatgaagtatacacccgtgggccgctcattcttctctgccccggagggttatgatcatcctctaggtggaggcagagaggtgtggttcggtttccatcagtctgttcggcccgccatgtggaaaatgatgctcaacattgatgtgtcagccacggctttctacaaagcacagccagtcattcagttcatgtgtgaagtcctggacatccacaacatcgacgagcagccgcgacccctcacagactcccacagagtcaaattcaccaaagaaatcaaaggtctgaaggtggaggtgacccactgcgggaccatgcggaggaagtaccgcgtctgcaatgtgacccgccggcctgccagccaccaaacgttccctttgcagttggagaacggccaaactgtagaacggacagtagctcagtatttcagagagaagtacaacctgcagctcaagtaccctcacctgccctgtctacaggtgggacaggagcagaaacacacatacctgcctctggaggtttgcaatattgtagcagggcagcggtgcatcaagaaactgacagataatcagacgtccaccatgatcaaagccacggcgcgctccgcaccagaccgacaggaggagatcagcagactggtgcgcagcgctaactatgaagccgacccgtccgtgcaggagtttcagtttaaggtccgggatgagatggcccacgtgacggggcgcgtgttgcccgcgcccatgctgcagtacgggggcagggtgagcacagagcactttatgaaccgcactgtcgccacaccgagtcacggcgtttgggacatgagaggaaagcggtttcacaccggcgtggagatcaagatgtgggccatcgcctgcttcgccacacagaggcagtgcagagaggagatcctcaagggttttaccgaccagctgcgcaaaatctcgaaggatgctgggatgccgattcagggtcagccgtgtttctgtaagtacgctcagggggccgacagcgtggagcccatgttcagacacctgaagaacacttactctggactgcagctcatcatcgtcatcctgcctggaaaaacccccgtctacgcggaagtgaagcgtgttggagacactcttctaggaatggccactcagtgtgtgcaggtgaagaacgtggtaaaaacctccccgcagacgctctccaacctctgcctgaaaatcaacgtcaaactcggcggcatcaacaacatcctcgtgccgcatcaacggccatcagttttccagcagccagtcatctttctgggggcggacgttacacatccccctgcaggagatgggaagaaaccgtccatcgcagcggtggtgggcagtatggacgctcatcccagcaggtattgtgccactgtgcgcgtccagagaccccgtcaggaggtcattcaggatttgtcctcaatggtgcgagagttactcatccagttctacaaatccactcgctacaagcccaccagaaccatcttctacagggacggtgtttctgagggccagttcagacaggtgttgtattatgagctgctggccattcgagaggcctgtatcagtctggagaaggagtaccagcccggcatcacgtatatagtggtgcagaaacgccaccacacacgcctcttctgtgccgaccgcagcgagagggtgggtcgcagtggaaacattcctgctggtacgacggtggatacagatatcacacacccttatgagtttgacttttacctctgcagtcatgctggaatacagggcaccagcaggccctcccactatcatgtcctgtgggacgacaactgcttcactgctgatgagttccagctgctcacctaccagctgtgccacacgtatgtgcgctgcacccgctccgtctccatccccgcgccagcctactacgcccacctggtggccttccgcgcccgataccacttggtggacaaagaacacgacagtgccgagggaagccatgtctccggacagagcaacggccgggacccccaagcgctggccaaagctgtgcagattcaccacgacaccctgaggaccatgtactttgcctaagccagctcacgttcatctagtcatgcacacaaacccgacaaccacacacacacacacacatgctgacaaacacacacacctcccagaatcctgtgcgtcctgaagggtcgatctctgtggcgattgaagcacggcccacccgacactgtgcagcaggacgaggaaggcctttaaggaagccgacctgctttaaaaccacacatggacctcggcgctattatgcaatattaaaccagccaactgag
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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