LOCUS       NM_001161597            1797 bp    mRNA    linear   VRT 09-APR-2020
DEFINITION  Danio rerio claudin domain containing 1b (cldnd1b), mRNA.
ACCESSION   NM_001161597 NM_001003751 XM_696446
VERSION     NM_001161597.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1797)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BX323839.13.
            
            On or before Jun 7, 2016 this sequence version replaced
            NM_001003751.1, XM_696446.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GFIL01022700.1, BC079497.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                BX323839.13        57630-57659         c
            31-526              BX323839.13        55854-56349         c
            527-634             BX323839.13        55535-55642         c
            635-772             BX323839.13        53735-53872         c
            773-1797            BX323839.13        51996-53020         c
FEATURES             Location/Qualifiers
     source          1..1797
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="1"
                     /map="1"
     gene            1..1797
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /note="claudin domain containing 1b"
                     /db_xref="GeneID:554386"
                     /db_xref="ZFIN:ZDB-GENE-040808-4"
     exon            1..30
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /inference="alignment:Splign:2.1.0"
     exon            31..526
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    100..102
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /note="upstream in-frame stop codon"
     CDS             232..993
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /codon_start=1
                     /product="claudin domain-containing protein 1b"
                     /protein_id="NP_001155069.1"
                     /db_xref="GeneID:554386"
                     /db_xref="ZFIN:ZDB-GENE-040808-4"
                     /translation="

MVDNRYATALVIGSVLSLLATVYLSVAMGTQHWFQYHSQPASNDINNGSDLQNLRLDFEGEDVDEMSYSKALFQLNGTLGLWWRCIRVHQDSHWFKAPDPVMVTKCQAFTLQQQWESKYKSPGNINTGEDLLRTYLWKCQFLLPLISVGLVFLAALIGVCACLCRSITPTLFVGLLHLMAGLCSLGTVCCFLTGLHLLHDISELPEGMDYSPGWSLFLALVSSPLQVMAAALFIWAARSHRQHYTRMTAYRVA"

     misc_feature    283..933
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
     exon            527..634
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /inference="alignment:Splign:2.1.0"
     exon            635..772
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /inference="alignment:Splign:2.1.0"
     exon            773..1797
                     /gene="cldnd1b"
                     /gene_synonym="zgc:100913"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atcatcagcccgaagggtgtgcgcaatatgatcacacattgctttgtcagtcaagacgtttcgcattgatgagcttgagataagacgatctgaattggataaacgttggaagatgaaaagaaaccagtgtttaaacagcacaaacgatatgaccgttgcatctctcaccaaactcatctgctaaacttaattgttagccatctgaaagtcatttttgcaacaaaaaacaacatggtggacaaccgttacgccacagcgctggtgatcggctctgtgttgagcctgcttgccactgtctatctgtctgttgcaatgggcactcagcactggttccagtaccacagccagccggccagcaacgacatcaacaacggctcagacctccagaacctccggctggactttgagggggaagatgtggatgagatgagctacagtaaagctctgttccagttgaacggcacgctgggtctgtggtggcgttgcattcgggtgcatcaagactcgcattggtttaaagcacctgatccagtgatggtgactaaatgtcaggcctttactttgcagcagcagtgggaatctaagtataaatcacctggaaatatcaacaccggagaagatctgctgcgtacatacctgtggaagtgtcagttcctgctgccgctgatctccgtgggtttggtgtttctcgcggcattaatcggagtgtgtgcctgtctgtgtcgcagtattactccaacactgttcgtagggctgctgcatctgatggctggcctgtgttccctggggaccgtttgctgtttcctcacgggactgcatttgcttcatgatatatcagagctgcccgaaggaatggactattctccaggctggtccttgtttttggcgctggtgtcgtctccgcttcaggtcatggcggctgcgcttttcatatgggctgcgaggagccaccgccaacactacactcgaatgacagcctacagagtcgcctgaacaaccaaggactgactataaagttggtgaagtggttcaaggaacgcgcacagcctattcacagctgcttttgccactaacaaagctgtgatgaagtaatgaaggataccatcagcccaaaattagtaagctaaactagcgccgtccacctatagcactcctgtgaaatacttgcatcacttgaaggatcttcctgctatattactgcctttttaaccacttattttagcctttgtggtaacattttacttgaaggggtgttcataagacataatatatttaaagggggaaattaagcactcagttaagtttacattattttgtatattggattccacttgaaaatataataaacaaacaattaatgtaaccatttagcagtaaacggcatgttttactatagattttagatctaggatgctaccatcttggaatgtcgctgtgtctgacatcacagggttggttctgttccctcaggtgaacggatactgtgaaagtaatggactgaaaacaaaaactgaaacagcctaatttaacccaatgtgtgcagttgtggacgtggagctggtgtaaatacaagcatcagatgtgtgtctaatataaaaatacattttctatttttctttttgcctcttttagttactgactatttggttcactatctgtattacgctgcctgactacctgtctgggtttcaagcatggcagtaacggactgaacacagagactggacagcctgatttaaccatgaagttgtggatgtgcatcgctggtgcaaatacaagcatttaagtgtcttaagt

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