LOCUS       NM_001114909            1268 bp    mRNA    linear   VRT 08-APR-2023
DEFINITION  Danio rerio acetylserotonin O-methyltransferase (asmt), mRNA.
ACCESSION   NM_001114909
VERSION     NM_001114909.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1268)
  AUTHORS   Dekens MPS, Fontinha BM, Gallach M, Pflugler S and Tessmar-Raible
            K.
  TITLE     Melanopsin elevates locomotor activity during the wake state of the
            diurnal zebrafish
  JOURNAL   EMBO Rep 23 (5), e51528 (2022)
   PUBMED   35233929
REFERENCE   2  (bases 1 to 1268)
  AUTHORS   Khan ZA, Yumnamcha T, Rajiv C, Sanjita Devi H, Mondal G, Devi SD,
            Bharali R and Chattoraj A.
  TITLE     Melatonin biosynthesizing enzyme genes and clock genes in ovary and
            whole brain of zebrafish (Danio rerio): Differential expression and
            a possible interplay
  JOURNAL   Gen Comp Endocrinol 233, 16-31 (2016)
   PUBMED   27179881
REFERENCE   3  (bases 1 to 1268)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC154029.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC154029.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1268
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="9"
                     /map="9"
     gene            1..1268
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /note="acetylserotonin O-methyltransferase"
                     /db_xref="GeneID:100141344"
                     /db_xref="ZFIN:ZDB-GENE-080220-43"
     exon            1..98
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..1064
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /EC_number="2.1.1.4"
                     /codon_start=1
                     /product="acetylserotonin O-methyltransferase"
                     /protein_id="NP_001108381.1"
                     /db_xref="GeneID:100141344"
                     /db_xref="ZFIN:ZDB-GENE-080220-43"
                     /translation="

MAEEAELYPKKILEYMEGFLVSKTLFSACELGVFELLQSACLSAGQVSAALSTSVDGTERLLSACVGLQLLNTHTHTDRTVLYSNTEMSNVFLVKSSPKSLYHSIEYSSRTIYLCWHYLSDAVRDGKNQYEKAFGVNSKDLFEALYRSDDEMVKFMHLMNSVWNICGRDVITAFDLTPYKTICDLGGCSGALAKQCVSAYPESSVTIFDLPRVVQNSQKHFMTDQDPRIAFCEGDFFKDELPQADLYILARILHDWTDQRSVELLTKIYQSCRPGGALLLAEALLHEDDSGPLTVQLYSLNMLVQTEGRERKASEYTRLLNAAGFTHVHTHTTGKIYDAVLAIK"

     misc_feature    60..326
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /note="dimerization domain; Region: dimerization2;
                     pfam16864"
                     /db_xref="CDD:435613"
     misc_feature    375..1004
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /note="O-methyltransferase; Region: Methyltransf_2;
                     pfam00891"
                     /db_xref="CDD:395719"
     exon            99..270
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            271..400
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            401..469
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            470..588
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            589..729
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            730..852
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1068
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1253
                     /gene="asmt"
                     /gene_synonym="hiomt; zgc:171885"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gaacaatcactgtgaacacacagaaaaacatggcagaagaagcggagctgtaccccaaaaagatcctcgaatacatggaggggttcctggtgtccaagactctgttctccgcctgtgagctgggtgtgtttgagctcctgcagtctgcgtgtctgtctgctggtcaggtttctgcagctctgagcaccagtgtggacgggacggagcgtctgctgtctgcgtgtgtggggctgcagctgctcaatacacacacacacaccgacagaactgttctgtacagtaacacagagatgtcgaatgtgttcctggtcaagtccagcccgaagtctctgtatcactctatcgagtacagctccagaaccatctacctgtgctggcattacctgagcgacgccgtccgagacgggaagaaccagtatgagaaagcctttggagtcaactctaaagacctgtttgaagccctctacaggtctgatgatgagatggtgaagtttatgcacctgatgaactcggtctggaatatctgcgggcgagacgtgatcacagccttcgacctgacaccgtacaagaccatctgtgacctcggaggctgcagtggagccctggccaaacagtgtgtgtcggcatacccagagtcttccgtcaccatctttgaccttcccagagtggtgcaaaactcacagaaacacttcatgacggaccaagacccgcgcatcgccttctgtgaaggagacttcttcaaggacgagctcccgcaggccgatctctacattctggcccggattctgcatgactggactgaccagcggagtgtggagctgctgaccaagatataccagtcctgtagaccaggtggagcgctgctgctggctgaagctcttcttcatgaggatgactctggtcctctgacggttcagctttattccctcaatatgttggtccagacggagggtcgcgagcgcaaggcttcagaatacacacgtctgctgaacgccgccggcttcacacacgtacacacacacaccaccggcaagatctatgacgctgttttggccatcaaataaatgaacacacacacacacacacacacacacacacacacacacacagacacacacagacacacacacactgatcagctggctctgaggctgtaaggcagttgttgctcagtttctgtttagtttacagcacaaatatctaaacctgatgtgtgtaaaattaagtataaataaataaaataaaataaaaaaaaaaaaaaaaaaaaa

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