2024-11-01 08:50:48, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001114715 1542 bp mRNA linear VRT 03-APR-2024 DEFINITION Danio rerio leucine zipper protein 2 (luzp2), transcript variant 1, mRNA. ACCESSION NM_001114715 VERSION NM_001114715.1 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. REFERENCE 1 (bases 1 to 1542) AUTHORS Thyme,S.B., Pieper,L.M., Li,E.H., Pandey,S., Wang,Y., Morris,N.S., Sha,C., Choi,J.W., Herrera,K.J., Soucy,E.R., Zimmerman,S., Randlett,O., Greenwood,J., McCarroll,S.A. and Schier,A.F. TITLE Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions JOURNAL Cell 177 (2), 478-491 (2019) PUBMED 30929901 REFERENCE 2 (bases 1 to 1542) AUTHORS Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S., Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M., Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y., Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B., Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R. TITLE RFX transcription factors are essential for hearing in mice JOURNAL Nat Commun 6, 8549 (2015) PUBMED 26469318 REMARK Publication Status: Online-Only COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC154442.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC154442.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..1542 /organism="Danio rerio" /mol_type="mRNA" /db_xref="taxon:7955" /chromosome="18" /map="18" gene 1..1542 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="leucine zipper protein 2" /db_xref="GeneID:100137118" /db_xref="ZFIN:ZDB-GENE-060503-278" exon 1..309 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" misc_feature 230..232 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="upstream in-frame stop codon" CDS 248..1288 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="isoform 1 precursor is encoded by transcript variant 1" /codon_start=1 /product="leucine zipper protein 2 isoform 1 precursor" /protein_id="NP_001108187.1" /db_xref="GeneID:100137118" /db_xref="ZFIN:ZDB-GENE-060503-278" /translation="
MKFIGAVYLLFLLPALSFNSSYEGLEKKLKEVFTERTGILRHLSKTSKELDSIKGNLQSLKNEDAVPKKDVQRILELSHKQRDEMKSLQAALQKQLDDAAERAEKQQATIKFLKMEMEKKTKIIKDLQQENKSLKNKLLSGNKLCDIHAEESKKIQAQLKELRYGKKDLIFKGQQLMDLENKLKVAKDELEKAALDKESQLKALKDTVHICFSSVLHSQTASLHRFPATPTNLLRYSALVNNSRVTFQQPHMKDIPKVPRITTTSKLPVSSAVMRRESTGPKDCQMVKVGSDCSHNQTESSSVMKKTFGHSQSKTPEQNGQGQARTAEESVKTDGELKKTQSDKHN"
misc_feature 248..>862 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning]; Region: EnvC; COG4942" /db_xref="CDD:443969" sig_peptide 248..298 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="COORDINATES: ab initio prediction:SignalP:6.0" mat_peptide 299..1285 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /product="Leucine zipper protein 2. /id=PRO_0000315277" /note="propagated from UniProtKB/Swiss-Prot (A5D8S1.2)" misc_feature 302..304 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (A5D8S1.2); glycosylation site" misc_feature 638..640 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (A5D8S1.2); glycosylation site" misc_feature 731..817 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="propagated from UniProtKB/Swiss-Prot (A5D8S1.2); Region: Leucine-zipper" misc_feature 968..970 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (A5D8S1.2); glycosylation site" misc_feature 1058..1285 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="propagated from UniProtKB/Swiss-Prot (A5D8S1.2); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" misc_feature 1133..1135 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (A5D8S1.2); glycosylation site" exon 310..421 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 422..492 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 493..574 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 575..637 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 638..700 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 701..763 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 764..838 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 839..1006 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 1007..1111 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 1112..1183 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" exon 1184..1531 /gene="luzp2" /gene_synonym="si:ch211-243k12.1; si:dkey-239j7.1; si:dkeyp-86e4.1" /inference="alignment:Splign:2.1.0" ORIGIN
tatttgaagccggagtgcctcgcactttcacatacacagaccgctcgcagcgttgcatctgtctgccgcggcgtgtgtgcctgcattaacgcgcgtgtgcaccacagacagagagagcgagagagagagagagagagagagagagagtggcgagccaaccaggagctaaagggagaagggaaaagcgagcgatcgagagaaaaagggggaaagagaaacgccgagtgcatgagagcaagacaaagcaatgaaattcatcggagccgtttacctcctgttcctcctccctgctttaagcttcaacagcagctatgaggggctggaaaagaagctgaaggaggttttcacagagaggacaggaattttacgacatctctccaaaacatcaaaggaactggacagcataaaaggaaacctgcagtcactgaagaatgaggatgctgtgcccaagaaggatgtgcagaggatcctggagctcagtcacaagcaaagggatgagatgaagtcactccaggcagctctgcagaaacaactggatgatgcagctgagcgtgcagagaaacagcaggccactataaagttcttaaagatggagatggaaaagaaaacgaaaatcatcaaagaccttcagcaagagaataaaagccttaagaacaaacttctgtccgggaacaagctctgtgacattcatgcagaagagtccaaaaaaatccaagcccaactgaaagagctgaggtatggcaaaaaggatttaatttttaagggtcaacagctgatggacttggagaacaaactcaaagtagccaaagatgaactggagaaggcagcgctggataaggagtcacagctaaaagccctgaaggacacagtgcatatctgcttctcgtctgttctacacagccagacagcaagtttacacagatttccagccacaccaaccaacctgttgaggtattcagccttggtcaacaactccagagtcacctttcagcagccacacatgaaggacatcccgaaagttccccggatcacaacaacaagtaaattgcctgtgagcagtgcggtaatgaggagagagagcacggggcccaaagactgccagatggtgaaggtgggatcagactgttcccacaatcagactgaaagctcatctgtgatgaaaaagacatttggacacagtcagtcgaagaccccagagcagaacggacaaggccaggcaaggacagcagaggaaagtgtgaaaacagatggggagctaaaaaagacacaatcggacaaacacaactgaagggacagtggaagacttggcagattttctgcatggtaaaaaaatgatgtcagatctgtttaagcccctcttcgttcactgagcttataagcacacacacacagatacatatgcacacaaacacgcgcacacacacacacactgtagccaaacacaatctacatacactaaatactcattctaacactgctaatgtagaaaagaaattcccaaaattaaattttgaacttttttaataaaaaaaaaaaaaaaaa
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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