LOCUS       NM_001045124             870 bp    mRNA    linear   VRT 09-APR-2020
DEFINITION  Danio rerio mesenchyme homeobox 2b (meox2b), mRNA.
ACCESSION   NM_001045124 XM_690253
VERSION     NM_001045124.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  AUTHORS   Nguyen PD, Hollway GE, Sonntag C, Miles LB, Hall TE, Berger S,
            Fernandez KJ, Gurevich DB, Cole NJ, Alaei S, Ramialison M,
            Sutherland RL, Polo JM, Lieschke GJ and Currie PD.
  TITLE     Haematopoietic stem cell induction by somite-derived endothelial
            cells controlled by meox1
  JOURNAL   Nature 512 (7514), 314-318 (2014)
   PUBMED   25119043
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BX957323.7.
            
            On Sep 1, 2006 this sequence version replaced XM_690253.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2168446,
                              SAMEA2168447 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="19"
                     /map="19"
     gene            1..870
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /note="mesenchyme homeobox 2b"
                     /db_xref="GeneID:566969"
                     /db_xref="ZFIN:ZDB-GENE-060503-853"
     CDS             1..870
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /note="homeobox protein MOX-2-like"
                     /codon_start=1
                     /product="homeobox protein MOX-2b"
                     /protein_id="NP_001038589.1"
                     /db_xref="GeneID:566969"
                     /db_xref="ZFIN:ZDB-GENE-060503-853"
                     /translation="

MDHSLFGCLRNPHAPSQALHPAFTQALHGRSDHISYPDLPGPSPPCSYAGEESSFGGAHHRVHPAPQHPHHPQHHQWHVPQMPSIESERHGLCLPHPDAAAPELCGTGAGSQGMCAGNPTLTGSDPSGVSCVPGEYGRQNMSPVEPERRSSKGKSDSSDSQDGSYKSDVSSKPRKERTAFTKEQIRELESEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQQGAAAREKELVNVKKGTLLPSEFSPMVGLHHPIGSPSNEDDSHDSDQSSDHAHL"

     misc_feature    order(520..534,538..540,589..591,607..609,646..648,
                     652..657,664..669,673..681,685..690)
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(526..528,535..537,655..657,664..669,676..678)
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    529..687
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     exon            1..475
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /inference="alignment:Splign:2.1.0"
     exon            476..648
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..870
                     /gene="meox2b"
                     /gene_synonym="si:ch211-127c19.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atggatcactctctgttcggatgccttcgaaacccgcatgccccgtctcaagctctgcacccggcgttcacccaggcactccatggccgctctgatcacatctcctaccccgacctcccgggaccttcaccgccctgcagctacgccggggaggagagcagttttggaggagctcatcacagagttcaccccgctccgcagcatccacaccacccgcagcatcatcagtggcacgtcccacagatgccgtctatagagagtgagcggcacgggctctgtctgccgcacccggacgctgctgctccagaactgtgcggcactggagcgggttcgcagggcatgtgcgccggtaacccaacactcactggaagtgacccttctggggtgtcatgcgtgcctggagagtacgggagacagaacatgtcacctgttgagccggaaagaaggagcagcaaaggaaagagcgacagttcagattcccaggatgggagctataagtcagacgtgagcagtaaacctaggaaggagcgcacggcgttcaccaaggaacagattcgagagctggagtcagaattcgctcaccacaactatctgacacggcttagacgttacgaaatcgctgtcaaccttgacctcacagagagacaagtgaaggtctggttccagaacagacggatgaagtggaagcgggtgaaaggaggtcaacagggagccgccgctagagagaaagagctggtgaacgtaaagaaagggactctcttaccctctgaattctccccgatggtgggactccatcatcctatcggctctcccagcaatgaggacgacagtcacgacagcgatcagagctccgatcatgcacatttatga

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