LOCUS       NM_001040360            2025 bp    mRNA    linear   VRT 28-DEC-2020
DEFINITION  Danio rerio claudin 30 (cldn30), mRNA.
ACCESSION   NM_001040360
VERSION     NM_001040360.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2025)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2025)
  AUTHORS   Baltzegar DA, Reading BJ, Brune ES and Borski RJ.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
COMMENT     PREDICTED REFSEQ: This record has not been reviewed and the
            function is unknown. The reference sequence was derived from
            BC115315.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC115315.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2025
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="21"
                     /map="21"
     gene            1..2025
                     /gene="cldn30"
                     /gene_synonym="zgc:136892"
                     /note="claudin 30"
                     /db_xref="GeneID:678612"
                     /db_xref="ZFIN:ZDB-GENE-060421-4745"
     exon            1..1996
                     /gene="cldn30"
                     /gene_synonym="zgc:136892"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    70..72
                     /gene="cldn30"
                     /gene_synonym="zgc:136892"
                     /note="upstream in-frame stop codon"
     CDS             97..981
                     /gene="cldn30"
                     /gene_synonym="zgc:136892"
                     /codon_start=1
                     /product="uncharacterized protein LOC678612 precursor"
                     /protein_id="NP_001035450.1"
                     /db_xref="GeneID:678612"
                     /db_xref="ZFIN:ZDB-GENE-060421-4745"
                     /translation="

MASLGMHMLASALALMGWTAALLCCILPMWRVTAFIGTTIVTSEIMWEGIWMNCVVQSTGQIQCKPYESTLALDVNLQASRALMVMSVIVGAVGLILTFIGGKCTIFLIRSERSKMKIVTAAGAILIIAGILCLIPPSWSAGMVVKAFYNPQLADPQRRELGGAIYLGWGGAIVLILSGGILCTSKCKDKPEDDRGPSVKYLVVRSSQAGSSRPGSQRMHPISVRSLQSGAPSVRSQWSQKAPFIQGRPQSVGSNQSRPTPTKSQFASSESMLVSEQDEGMSTKSQLFHDGFIH"

     sig_peptide     97..159
                     /gene="cldn30"
                     /gene_synonym="zgc:136892"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     misc_feature    109..642
                     /gene="cldn30"
                     /gene_synonym="zgc:136892"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
ORIGIN      

gcaatgagcgaggaagcaaacatcacaaggccttcaaaaaggctttgagaaaaacaaagaggcctcaaatagctgtggacgtttaaccccggcacaatggcgtccctcggcatgcacatgctggcgagcgctttggctttaatgggatggaccgcagccctcctgtgctgcatcctgccaatgtggcgagtgacagccttcatcggaaccaccatcgtcacctcagagatcatgtgggaaggcatctggatgaactgcgtggtacagagcacaggtcaaatccagtgcaagccgtatgaatcgacactcgctctagatgtgaatctgcaggcctctcgggccctcatggttatgtccgtcattgttggagctgtgggcctcattttgaccttcattggaggaaagtgcaccatttttctgatcagatccgaaagatccaaaatgaagattgtcacagcggcaggtgccattttaatcattgcaggaattctctgcttgatcccaccctcatggtcggctggcatggtggtaaaggcgttttacaatccacagttagcggatccacagcgcagagagcttggaggggccatttatcttggttgggggggagccattgtcctcatattgagtggaggaattctttgcacctccaaatgtaaagacaaaccagaggatgaccgtggtccttcggtgaagtatctggttgtgcgatcttcgcaggcaggatccagcaggccgggctctcaaaggatgcatccaatctctgtgaggtcacttcagagtggtgccccatctgtgaggtcccagtggagtcagaaagccccttttattcagggcagacctcagtcagtaggctccaaccagagcaggccaacacctacaaagtcgcagtttgccagttctgaatcaatgctagtgtctgagcaggacgaggggatgtcaacaaagtcccagctgtttcatgatggcttcatacactgaccaactcaacaagagagatgctccattgacatgcttttgattgtggagactgcaaaaagtatgcagatcaagagacttgcacttggacagtcatatatctgccattgcactattaattactgctattattgataaaatgaaggattctaatgaaggctgaaattattgcttgtcaattattaggcatttttgaagaagtggaggcactttaagaggtccttgaggtataaggaaactgactgaggtaatttgcactgaactacactcaaacctcaggagccaagattatcgttgttgctattatagttcatttctaaaagtatgtatgtgtgtacacctactcgaagtaattcatattcttcattgtgtgtcttatataagcctcatgttacctacaaaattcaatggacaatgtggccatcagtaagctacttacaaaagcttgttcttatatgtaacataaaaagctgatgcctcttcaacaagcatacagaatttttttgtttcattcaaatctcatgttttgcttcctgttaggaaactagaatgaacacatttctgatgtatgaagcactgctatgaccttgccgacattggtggtctttcatagttggacaatggtttggttcagattttacaagggagggaaaagtacactctcttctttgttagcctttcttctacgtcaattcgagccctcagtgaaacggcagatccaggcaaaaccggttcaacagagagtatcacctcgtaatagcgctttgcattttgtcagtacaaagagcatttaaaaagagttcaatggagtgtgctgtaatgaggctacttgtttagacaaaagttagcaatattcaacagtttcgtttaaaataaattgattagctacaaaagtttataaagtataaatacaacacttcctgaatacttttatgccattataatgtctgtttaatgaaaacactgtgatgctgcatgtttccggaaatgcaagctaataaattatttttaaactgtgaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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