LOCUS       NM_001025532             810 bp    mRNA    linear   VRT 29-MAY-2023
DEFINITION  Danio rerio ladybird homeobox 1a (lbx1a), mRNA.
ACCESSION   NM_001025532 XM_687459
VERSION     NM_001025532.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 810)
  AUTHORS   Wang J, Thomas HR, Thompson RG, Waldrep SC, Fogerty J, Song P, Li
            Z, Ma Y, Santra P, Hoover JD, Yeo NC, Drummond IA, Yoder BK, Amack
            JD, Perkins B and Parant JM.
  TITLE     Variable phenotypes and penetrance between and within different
            zebrafish ciliary transition zone mutants
  JOURNAL   Dis Model Mech 15 (12) (2022)
   PUBMED   36533556
REFERENCE   2  (bases 1 to 810)
  AUTHORS   Nord H, Kahsay A, Dennhag N, Pedrosa Domellof F and von Hofsten J.
  TITLE     Genetic compensation between Pax3 and Pax7 in zebrafish
            appendicular muscle formation
  JOURNAL   Dev Dyn 251 (9), 1423-1438 (2022)
   PUBMED   34435397
REFERENCE   3  (bases 1 to 810)
  AUTHORS   Juarez-Morales JL, Weierud F, England SJ, Demby C, Santos N, Grieb
            G, Mazan S and Lewis KE.
  TITLE     Evolution of lbx spinal cord expression and function
  JOURNAL   Evol Dev 23 (5), 404-422 (2021)
   PUBMED   34411410
REFERENCE   4  (bases 1 to 810)
  AUTHORS   Talbot JC, Teets EM, Ratnayake D, Duy PQ, Currie PD and Amacher SL.
  TITLE     Muscle precursor cell movements in zebrafish are dynamic and
            require Six family genes
  JOURNAL   Development 146 (10) (2019)
   PUBMED   31023879
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 810)
  AUTHORS   Masselink W, Masaki M, Sieiro D, Marcelle C and Currie PD.
  TITLE     Phosphorylation of Lbx1 controls lateral myoblast migration into
            the limb
  JOURNAL   Dev Biol 430 (2), 302-309 (2017)
   PUBMED   28843494
REFERENCE   6  (bases 1 to 810)
  AUTHORS   Jovelin R, Yan YL, He X, Catchen J, Amores A, Canestro C, Yokoi H
            and Postlethwait JH.
  TITLE     Evolution of developmental regulation in the vertebrate FgfD
            subfamily
  JOURNAL   J Exp Zool B Mol Dev Evol 314 (1), 33-56 (2010)
   PUBMED   19562753
REFERENCE   7  (bases 1 to 810)
  AUTHORS   Sabo MC, Nath K and Elinson RP.
  TITLE     Lbx1 expression and frog limb development
  JOURNAL   Dev Genes Evol 219 (11-12), 609-612 (2009)
   PUBMED   20091319
REFERENCE   8  (bases 1 to 810)
  AUTHORS   Wotton KR, Weierud FK, Juarez-Morales JL, Alvares LE, Dietrich S
            and Lewis KE.
  TITLE     Conservation of gene linkage in dispersed vertebrate NK homeobox
            clusters
  JOURNAL   Dev Genes Evol 219 (9-10), 481-496 (2009)
   PUBMED   20112453
REFERENCE   9  (bases 1 to 810)
  AUTHORS   Ochi H and Westerfield M.
  TITLE     Lbx2 regulates formation of myofibrils
  JOURNAL   BMC Dev Biol 9, 13 (2009)
   PUBMED   19216761
  REMARK    Publication Status: Online-Only
REFERENCE   10 (bases 1 to 810)
  AUTHORS   Wotton KR, Weierud FK, Dietrich S and Lewis KE.
  TITLE     Comparative genomics of Lbx loci reveals conservation of identical
            Lbx ohnologs in bony vertebrates
  JOURNAL   BMC Evol Biol 8, 171 (2008)
   PUBMED   18541024
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL928816.2.
            
            On Jul 16, 2005 this sequence version replaced XM_687459.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA3505370,
                              SAMEA3505371 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..810
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="13"
                     /map="13"
     gene            1..810
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /note="ladybird homeobox 1a"
                     /db_xref="GeneID:564103"
                     /db_xref="ZFIN:ZDB-GENE-040724-40"
     CDS             1..810
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /note="ladybird homeobox 1b"
                     /codon_start=1
                     /product="transcription factor LBX1a"
                     /protein_id="NP_001020703.1"
                     /db_xref="GeneID:564103"
                     /db_xref="ZFIN:ZDB-GENE-040724-40"
                     /translation="

MTSKEDAKGASVEDRRRSPLDHLPPPANSNKPLTPFSIEDILNKPSVKRSYTICGTAHLLSSGEKHPSTGHPLSNRALLTQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTLFGQRNTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKAVGNVPFEKMAKLADLEKRVNGTLGDSSAVSPSRSNHEHEGTNKLHMSPSSPYTDHTTSKECSEDEDEEIDVDD"

     misc_feature    order(376..390,394..396,445..447,463..465,502..504,
                     508..513,520..525,529..537,541..546)
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    382..543
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(382..384,391..393,511..513,520..525,532..534)
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            1..325
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /inference="alignment:Splign:2.1.0"
     exon            326..810
                     /gene="lbx1a"
                     /gene_synonym="dZ265N4.1; lbx1b; si:busm1-265n4.1;
                     si:ch211-103o12.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atgacctccaaagaagacgcgaaaggcgcctcggttgaggaccgaaggcgcagtccgttggaccatcttcctccacctgctaactcaaacaaacctctcactccgttcagcatagaggatattttgaacaagccgtctgtcaaacgaagttacacaatttgcggcacggcgcacctgctttcttccggtgagaagcatccgtccacgggccatcccctctccaaccgtgcgctgctcacccagacatctccactgtgcgccctggaggagctcgccagcaaaaccttcaaggggctggaagtcagtgtcttacaagcggcagaagggagagacggcatgacactcttcggtcagaggaatacccctaaaaaacggagaaagtcgagaacagctttcaccaatcaccaaatctacgaacttgagaagagatttctctatcagaaatatctgtctccggctgatcgagatcagatcgctcagcagctcgggctcacgaatgctcaagtcatcacctggttccagaatcgccgagccaaactcaaaagagacctagaggagatgaaggcggacgtggagtcggccaaagcggtgggcaatgtaccttttgagaaaatggccaaactggcagacctagagaaacgtgtgaacggtacactcggagattcatcggccgtgtctccgtcacgatctaatcacgagcacgagggcaccaacaaactccacatgtcaccatcatcgccatatacagaccacacaacgagcaaagagtgttcagaagacgaagacgaggaaattgatgtagatgactga

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