2024-11-01 08:21:21, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001020614 1640 bp mRNA linear VRT 03-JUL-2021 DEFINITION Danio rerio exoribonuclease 1 (eri1), mRNA. ACCESSION NM_001020614 XM_696796 VERSION NM_001020614.1 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. REFERENCE 1 (bases 1 to 1640) AUTHORS Wang S, Ji D, Yang Q, Li M, Ma Z, Zhang S and Li H. TITLE NEFLb impairs early nervous system development via regulation of neuron apoptosis in zebrafish JOURNAL J Cell Physiol 234 (7), 11208-11218 (2019) PUBMED 30569449 REFERENCE 2 (bases 1 to 1640) AUTHORS Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and Bobe J. TITLE Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database JOURNAL BMC Genomics 17, 368 (2016) PUBMED 27189481 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 1640) AUTHORS Zhao XF, Fjose A, Larsen N, Helvik JV and Drivenes O. TITLE Treatment with small interfering RNA affects the microRNA pathway and causes unspecific defects in zebrafish embryos JOURNAL FEBS J 275 (9), 2177-2184 (2008) PUBMED 18384379 REFERENCE 4 (bases 1 to 1640) AUTHORS Eckfeldt CE, Mendenhall EM, Flynn CM, Wang TF, Pickart MA, Grindle SM, Ekker SC and Verfaillie CM. TITLE Functional analysis of human hematopoietic stem cell gene expression using zebrafish JOURNAL PLoS Biol 3 (8), e254 (2005) PUBMED 16089502 REFERENCE 5 (bases 1 to 1640) AUTHORS Kennedy S, Wang D and Ruvkun G. TITLE A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans JOURNAL Nature 427 (6975), 645-649 (2004) PUBMED 14961122 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095343.1. On Jul 6, 2005 this sequence version replaced XM_696796.1. ##Evidence-Data-START## Transcript exon combination :: BC095343.1, BC164140.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..1640 /organism="Danio rerio" /mol_type="mRNA" /strain="Singapore" /db_xref="taxon:7955" /chromosome="21" /map="21" gene 1..1640 /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="exoribonuclease 1" /db_xref="GeneID:553641" /db_xref="ZFIN:ZDB-GENE-050522-39" exon 1..353 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" misc_feature 240..242 /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="upstream in-frame stop codon" CDS 270..1283 /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="three prime histone mRNA exonuclease 1" /codon_start=1 /product="3'-5' exoribonuclease 1" /protein_id="NP_001018450.1" /db_xref="GeneID:553641" /db_xref="ZFIN:ZDB-GENE-050522-39" /translation="
METKEKSRKPPNKTPQSEGDQEDQPCPDTSCEKNEDQEPSSPKQGEFSDPVYKEIALANGAINRMNREELRAKCTELKLDTRGVNDVLRKRLKSYYKKQKLMHSPAAEGNSDMYFDYICVVDFEATCEENNPPDYLHEIIEFPMVLIDTHTLEIVDSFQEYVKPVLHPQLSEFCVKLTGITQEMVDEAKTFHQVLKRAISWLQEKELGTKYKYMFLTDGSWDMGKFLHTQCKLSRIRYPQFARKWINIRKSYGNFYKVPRTQTKLICMLENLGMEYDGRPHCGLDDSRNIARIAIHMLKDGCQLRVNECLHSGEPRSVPISAPIEGAPAPQPPKKRD"
misc_feature 453..557 /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="SAP domain; Region: SAP; pfam02037" /db_xref="CDD:460424" misc_feature 621..1163 /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133" /db_xref="CDD:99836" misc_feature order(633..644,648..650,786..788,921..935,945..947, 1110..1112,1125..1127) /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="active site" /db_xref="CDD:99836" misc_feature order(633..644,648..650,786..788,921..935,945..947, 1110..1112,1125..1127) /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="substrate binding site [chemical binding]; other site" /db_xref="CDD:99836" misc_feature order(633..635,639..641,933..935,1110..1112,1125..1127) /gene="eri1" /gene_synonym="thex1; zgc:110635" /note="catalytic site [active]" /db_xref="CDD:99836" exon 354..514 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" exon 515..731 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" exon 732..815 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" exon 816..925 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" exon 926..1040 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" exon 1041..1610 /gene="eri1" /gene_synonym="thex1; zgc:110635" /inference="alignment:Splign:2.1.0" ORIGIN
gtggaagttgaaacgtcagtgagtgtcagcggcagcgtgattcacgtttgagaaactaactgcacgcaaccagaagttttactatcaggcacctatttatatcaaaatgtacatgcagcaaactgaagacatcgagacgagcatttagtgttgaaatattttaaagtggattaagtacatgtaacgttagagacaccgcgacgcttaacgcgcgaaaccagatgtgagtgtttctgaaatgatctaacgttactagactttcagatctgatggagacgaaggaaaagagccgtaaacctccaaataagactccacagtctgaaggagatcaggaggatcaaccctgtcctgatacttcctgtgaaaaaaatgaagatcaggagccttcctcaccaaaacagggagagttcagtgatccggtgtataaagagattgcattggcaaatggtgccatcaaccgaatgaacagagaagagttgcgtgcgaaatgcacagagctgaaacttgacacacgtggagttaatgatgtcctaaggaagcgcctcaaaagctactacaaaaagcagaagttgatgcattcacctgctgcagaagggaacagtgacatgtactttgactacatctgtgtggtggattttgaagcaacatgcgaagagaataacccaccagattacctccatgaaatcattgagttccccatggtgttgatcgacacacacacactggagattgtagactcgtttcaggagtatgtgaagccagtgctgcacccacagctctctgagttttgtgtaaaacttaccggaataacgcaggaaatggtggatgaggcaaaaacattccatcaagttttaaagcgagcaatttcttggcttcaggaaaaagaactgggcacaaaatacaaatatatgtttttgacagacgggtcttgggacatggggaaatttcttcatacacagtgcaaactgagtcgcatcagatacccacagtttgccagaaaatggatcaatatcagaaagtcttatgggaatttttataaggttcctcgtactcagacgaagctgatctgcatgctggagaatctggggatggagtatgatggacgtccgcactgtggtctagatgactcacgcaacattgccagaatcgccatccacatgctgaaggacggctgtcagctgagggtgaatgagtgcttgcattcaggagaaccgcggagcgtgcctatctctgcccctattgaaggagcaccagcacctcagccccccaaaaaacgagactagaaagactctttgccaaaaaaataacaacaaatatgaaaacctgccatgttgtggaaaaatgatctagattaataaatattgaaatatttgctgagagaattgtacatcataacagatgatgaagcttcaccattacagcaaattggtttcatgtactgtatttggaacttgctcctgagaaacatacactgcaggaagtgtttatttccagcctgatgggtaattagtaattgttgtattttttaaaatccctattgcacatacattttgcagctctgctctacatgtattattttgccaataaactttttagtgatggtgagattgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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