LOCUS       NM_001006029             954 bp    mRNA    linear   VRT 20-DEC-2022
DEFINITION  Danio rerio trafficking protein particle complex subunit 6B
            (trappc6b), mRNA.
ACCESSION   NM_001006029
VERSION     NM_001006029.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 954)
  AUTHORS   Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev
            D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW,
            Imam FB, Zaki MS and Gleeson JG.
  TITLE     A homozygous founder mutation in TRAPPC6B associates with a
            neurodevelopmental disorder characterised by microcephaly, epilepsy
            and autistic features
  JOURNAL   J Med Genet 55 (1), 48-54 (2018)
   PUBMED   28626029
REFERENCE   2  (bases 1 to 954)
  AUTHORS   Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A,
            Choudhary JS, Emes RD and Grant SG.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 954)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 954)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083391.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083391.1, EH450189.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..954
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="23"
                     /map="23"
     gene            1..954
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="trafficking protein particle complex subunit 6B"
                     /db_xref="GeneID:450008"
                     /db_xref="ZFIN:ZDB-GENE-041010-122"
     exon            1..282
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    118..120
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="upstream in-frame stop codon"
     CDS             205..678
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="TRAPP complex subunit 6B; trafficking protein
                     particle complex 6b"
                     /codon_start=1
                     /product="trafficking protein particle complex subunit 6b"
                     /protein_id="NP_001006029.1"
                     /db_xref="GeneID:450008"
                     /db_xref="ZFIN:ZDB-GENE-041010-122"
                     /translation="

MADEALFQFLHSEIIQYVNSAETGESENGRCVSKLENMGFRVGQGLIERFTQDTPRFKDELDVMKFICKDFWTSVFKKQIDNLRTNHQGIYVLQDNKFRLLTQLSAGKQYLEHAPKFLAFTCGLVRGALSNIGVKSIVTAEVSVMPACKFQVMIQKM"

     misc_feature    211..669
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="Trs33 subunit of the TRAPP complex; Region:
                     TRAPPC6A_Trs33; cd14944"
                     /db_xref="CDD:271347"
     misc_feature    order(217..219,226..228,238..240,508..513,541..543,
                     553..555)
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="synbindin interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:271347"
     misc_feature    order(220..225,229..237,241..246,253..255,304..306,
                     316..318,325..330,337..342,349..351,424..426,433..435,
                     493..495,562..564)
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /note="BET3 interface [polypeptide binding]; other site"
                     /db_xref="CDD:271347"
     exon            283..350
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            351..468
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            469..552
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            553..646
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
     exon            647..937
                     /gene="trappc6b"
                     /gene_synonym="zgc:103464"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aggaagtggaaccaatgtaaagaaggaccattcctttcaatcgaaaacactagcaaaatatttcacctataatgacattcgcacaatgaatagctgtctgtttattgaagcagcagttgatttatacctgtagtcggattggttggttctgccgttgttcgtcgccggtcagtttcagtggggcatcggctggactggctcgagatggcagatgaggctctttttcagttcctacacagtgaaatcattcagtatgtcaacagtgcagaaactggggaatcggagaatggacgatgtgtttctaaacttgagaacatgggctttcgtgtgggacaaggacttattgagaggtttacccaagacacgccacgctttaaagatgagcttgacgttatgaagttcatctgcaaagatttctggaccagtgtttttaagaagcagattgacaacctgagaacaaaccaccagggtatttatgtactacaagataacaagttccgcctactgacccaactgtctgctggcaaacagtatctggaacatgcgccgaagtttttagccttcacttgtggactggtccgaggagcactttcaaacattggtgtgaaaagtatcgtcacggcggaagtgtcagtcatgcctgcctgtaaattccaggtgatgattcagaagatgtgattcactacaatggagcatatagttcacaacgtgcatctcagttttattgccttgtcgttttttattgcctgcacattttatcaataatatcactatgaagtttttttttttaatttgcagtaacttgaaaactactggcattaaatgtattttgacatgtactgtattttttgttagtattttgacactcattatctgtccatattcactgttctgattattcatttgcactaatagcattaaagctagaatcctgctaaaaaaaaaaaaaaaaaa

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