LOCUS       NM_001002340            1592 bp    mRNA    linear   VRT 05-AUG-2023
DEFINITION  Danio rerio claudin 7a (cldn7a), mRNA.
ACCESSION   NM_001002340
VERSION     NM_001002340.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1592)
  AUTHORS   Garcia-Concejo A and Larhammar D.
  TITLE     Protein kinase C family evolution in jawed vertebrates
  JOURNAL   Dev Biol 479, 77-90 (2021)
   PUBMED   34329618
REFERENCE   2  (bases 1 to 1592)
  AUTHORS   Li X, Song G, Zhao Y, Zhao F, Liu C, Liu D, Li Q and Cui Z.
  TITLE     Claudin7b is required for the formation and function of inner ear
            in zebrafish
  JOURNAL   J Cell Physiol 233 (4), 3195-3206 (2018)
   PUBMED   28834538
REFERENCE   3  (bases 1 to 1592)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1592)
  AUTHORS   Carvalho CM, Vasanth S, Shinawi M, Russell C, Ramocki MB, Brown CW,
            Graakjaer J, Skytte AB, Vianna-Morgante AM, Krepischi AC, Patel GS,
            Immken L, Aleck K, Lim C, Cheung SW, Rosenberg C, Katsanis N and
            Lupski JR.
  TITLE     Dosage changes of a segment at 17p13.1 lead to intellectual
            disability and microcephaly as a result of complex genetic
            interaction of multiple genes
  JOURNAL   Am J Hum Genet 95 (5), 565-578 (2014)
   PUBMED   25439725
REFERENCE   5  (bases 1 to 1592)
  AUTHORS   Baltzegar DA, Reading BJ, Brune ES and Borski RJ.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
REFERENCE   6  (bases 1 to 1592)
  AUTHORS   Davey C, Tallafuss A and Washbourne P.
  TITLE     Differential expression of neuroligin genes in the nervous system
            of zebrafish
  JOURNAL   Dev Dyn 239 (2), 703-714 (2010)
   PUBMED   20063411
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC075926.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC075926.1, EG576581.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1592
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="7"
                     /map="7"
     gene            1..1592
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="claudin 7a"
                     /db_xref="GeneID:436612"
                     /db_xref="ZFIN:ZDB-GENE-040718-29"
     exon            1..419
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    155..157
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="upstream in-frame stop codon"
     CDS             197..835
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="claudin 7 like"
                     /codon_start=1
                     /product="claudin-7-A"
                     /protein_id="NP_001002340.1"
                     /db_xref="GeneID:436612"
                     /db_xref="ZFIN:ZDB-GENE-040718-29"
                     /translation="

MANSGVQLLGFGLSLIGIIGLIVGTILPQWKMSAYVGDSIITAVATYQGLWMSCAFQSTGQLQCKIYDSILQLDSDLQATRALMIVGIIVSIAGLGVASIGMKCTTCGADDKVRKTRTAMTGGIILLVGALCAVVACSWFAHNVIRAFYNPFTPVNTKFEFGAAIFIAWGGSFLDVLGGAMLAASCPRSKQVSKYPKSNSTRSANGSNKEYV"

     misc_feature    206..742
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
     misc_feature    218..280
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    440..502
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    554..616
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    683..745
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     transmembrane region"
     misc_feature    767..832
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6DHP1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            420..584
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
     exon            585..669
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
     exon            670..1552
                     /gene="cldn7a"
                     /gene_synonym="zgc:92192"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcctataaacacatccagctgcgtgactggctgctaggttttgttttgggggaaaagttccacagcttcatcgtcagtatagtctgagcgttcctccagagaggaacaggtgcgggacaggataagggattatcgacgtttctctaaagtttattgaaaactgttgctcagcttgccatttaagcttcgaaaagaaatggcaaactcgggcgttcagttgcttgggttcggtctctctctgattggcatcattggactgatcgtgggcaccatcctgccccagtggaagatgtccgcgtatgtgggagacagtatcatcaccgcagtggccacttaccagggactgtggatgtcctgcgcatttcagagcaccggacaacttcagtgcaaaatctatgactctattctgcagctggacagtgacctgcaagcaacccgagctttgatgattgtggggatcattgtgtccattgctggtctcggtgtggccagtataggcatgaagtgcaccacttgtggagctgacgacaaagttcgcaagactcgcacggccatgactggaggcatcatacttcttgtaggagccctctgtgcagttgtcgcctgctcgtggtttgcccataatgtgatccgagcattctacaaccccttcactccagtcaacaccaagtttgagtttggagcagccattttcatagcttggggtggctcatttcttgatgttctcggtggagccatgttggctgcctcttgccctcgaagtaaacaagtgtcaaaatatcctaaaagtaactctacacgatcagccaacggcagcaacaaagagtatgtgtgagcaagactgcctctcactggacagacattgtaacagcttcaaaaggtgaagactttcttcagcagaataatcactgagcatgctgttgaagaaatgaggtgagaaacgagaaggaaaaccgctcacactgttgaatgttcccttgataaaaaagtggcaaccagttgtctaaaagtttgaataaaaatatatatttacaaactctatgggaggttttaaaatggaggattgtagaaatctagcgccagtagaaatactcacagccctcagtgcttcagctaagttgttttatgtgtgtaattaaggaggagaaacttttgatagtgggccaaatatgtcggcgttcccaaagtgtccactagggagcactagaaacaacacaatgagcaagtgtttcctaaaatgggagagatttcccagagcttttgtttgtggagtgtttatcctacaacagacgaagtgctaacattattaacactcacatgagtcattgttgtgtagtttgatgtaatcacagtgtttgaagtattataaatcttctttcttttactaaacacatttctgcattaactcacacttgtcattactttacccataagcccttttgaatactacatatagtacttataaatgcttcccgataatgtaaatgttagttaaatattgttcatacatttgtgttacatgcttattttcaataaatttgctttcatcctaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

//