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2024-11-01 08:15:47, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       NM_001002194            1253 bp    mRNA    linear   VRT 03-APR-2024
DEFINITION  Danio rerio centrosomal protein 41 (cep41), mRNA.
ACCESSION   NM_001002194
VERSION     NM_001002194.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Ki,S.M., Kim,J.H., Won,S.Y., Oh,S.J., Lee,I.Y., Bae,Y.K.,
            Chung,K.W., Choi,B.O., Park,B., Choi,E.J. and Lee,J.E.
  TITLE     CEP41-mediated ciliary tubulin glutamylation drives angiogenesis
            through AURKA-dependent deciliation
  JOURNAL   EMBO Rep 21 (2), e48290 (2020)
   PUBMED   31885126
REFERENCE   2  (bases 1 to 1253)
  AUTHORS   Patowary,A., Won,S.Y., Oh,S.J., Nesbitt,R.R., Archer,M.,
            Nickerson,D., Raskind,W.H., Bernier,R., Lee,J.E. and Brkanac,Z.
  TITLE     Family-based exome sequencing and case-control analysis implicate
            CEP41 as an ASD gene
  JOURNAL   Transl Psychiatry 9 (1), 4 (2019)
   PUBMED   30664616
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1253)
  AUTHORS   Lee,J.E., Silhavy,J.L., Zaki,M.S., Schroth,J., Bielas,S.L.,
            Marsh,S.E., Olvera,J., Brancati,F., Iannicelli,M., Ikegami,K.,
            Schlossman,A.M., Merriman,B., Attie-Bitach,T., Logan,C.V.,
            Glass,I.A., Cluckey,A., Louie,C.M., Lee,J.H., Raynes,H.R.,
            Rapin,I., Castroviejo,I.P., Setou,M., Barbot,C., Boltshauser,E.,
            Nelson,S.F., Hildebrandt,F., Johnson,C.A., Doherty,D.A.,
            Valente,E.M. and Gleeson,J.G.
  TITLE     CEP41 is mutated in Joubert syndrome and is required for tubulin
            glutamylation at the cilium
  JOURNAL   Nat Genet 44 (2), 193-199 (2012)
   PUBMED   22246503
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC072712.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC072712.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="25"
                     /map="25"
     gene            1..1253
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="centrosomal protein 41"
                     /db_xref="GeneID:431741"
                     /db_xref="ZFIN:ZDB-GENE-040704-35"
     exon            1..72
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    13..15
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="upstream in-frame stop codon"
     CDS             40..1164
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="testis specific, 14; testis-specific gene A14
                     protein"
                     /codon_start=1
                     /product="centrosomal protein of 41 kDa"
                     /protein_id="NP_001002194.1"
                     /db_xref="GeneID:431741"
                     /db_xref="ZFIN:ZDB-GENE-040704-35"
                     /translation="
MSVKRGIGDSAFLKKKIPQNPKYQHVKTRLDTGSSLTKYMERLEEARKNYRYRKDELFKRLKVTTFAQLVIQVASVSDQNDNIKDEMAGLEDDVSIFSASPGLDCLSDQTNGSPQPNLPPPQTINIDESGDNGFSPRSTLQSVISGVGELDLDKNGQKTIRLSPVSTSNTTECPYPDCPYLLLDVRDRELYDQCHIVSAYSYPIATLSRTMNPYTKEVLDYKNASGKIIIVYDEDERIASQAATTMCERGFENLFMLSGGLKVVAQKFPEGMTTGSVPISCLPSPTGPAGRKRSAQHQTSQLAEKKWRFTAEDLDKIQHYLEEVFIPSETSSRLSSRMSTSSARSKASTVGSSRQGSSIAGSESARSRSSRPWK"
     misc_feature    568..825
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="Rhodanese-like domain; Region: Rhodanese;
                     pfam00581"
                     /db_xref="CDD:425764"
     misc_feature    736..738
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="active site residue [active]"
                     /db_xref="CDD:238089"
     misc_feature    874..942
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6GQN0.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1024..1161
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6GQN0.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            73..136
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            137..184
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            185..246
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            247..313
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            314..464
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            465..634
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            635..702
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            703..817
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            818..1033
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1229
                     /gene="cep41"
                     /gene_synonym="tsga14; zgc:91859"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
ggtagctaacattagccgccgaagctctgctgctggaagatgtcggtgaagagggggattggcgattcagcgtttttaaagaagaagattcctcagaacccaaaatatcagcatgtaaaaacaaggcttgatacaggctccagcctgacaaaatacatggagagactagaggaggcaagaaaaaactacagatataggaaggacgagttgtttaagagactgaaagtgaccacatttgcacagctggtaatccaagttgcttcggtatcagatcagaatgacaacattaaagatgaaatggcgggattagaagatgatgtttcgatattctctgcatcaccgggcctcgactgtctctccgatcagactaatggctccccacaaccaaaccttcctcctccacagaccatcaacattgacgaatccggcgacaatggcttttctcccagatctacacttcaaagtgtcatcagtggcgtgggagaattagatctggacaagaacggacagaagaccatccggctgtctccggtttctacctccaacaccacagagtgtccctatcccgactgcccatatctgttgctggatgtgcgggacagagagctgtatgaccagtgccatattgtcagtgcgtatagctaccctattgcaaccttatcaaggacgatgaacccgtacacaaaagaagtgcttgactacaaaaatgcatctggaaagatcatcatcgtgtatgacgaggatgagaggatagcaagtcaagcagccactaccatgtgtgaaagaggcttcgagaatcttttcatgctgtcgggggggttaaaagtggttgctcagaagtttccagaaggaatgacgaccggctcagttcccatctcctgtttgccatcaccaacaggccctgcaggacgcaagcgatcagcacagcaccagacatcacagttggcagagaaaaagtggcggttcacagcagaagatcttgacaaaatccagcattaccttgaggaggtgttcatacccagtgaaaccagcagtcgcctcagcagcagaatgtccactagcagcgctcgctccaaagcgtctacagtcggtagcagtcgacaaggttcatccatagcaggatcagaaagtgctcgttcaagaagtagtcgaccctggaaataaccctcgctttcacctggtcacagcttcacttcaatgcataaataaatccatgctgttttactttaaaaaaaaaaaaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]