2024-11-01 08:15:47, GGRNA.v2 : RefSeq release 226 (Sep, 2024)
LOCUS NM_001002194 1253 bp mRNA linear VRT 03-APR-2024 DEFINITION Danio rerio centrosomal protein 41 (cep41), mRNA. ACCESSION NM_001002194 VERSION NM_001002194.1 KEYWORDS RefSeq. SOURCE Danio rerio (zebrafish) ORGANISM Danio rerio Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio. REFERENCE 1 (bases 1 to 1253) AUTHORS Ki,S.M., Kim,J.H., Won,S.Y., Oh,S.J., Lee,I.Y., Bae,Y.K., Chung,K.W., Choi,B.O., Park,B., Choi,E.J. and Lee,J.E. TITLE CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation JOURNAL EMBO Rep 21 (2), e48290 (2020) PUBMED 31885126 REFERENCE 2 (bases 1 to 1253) AUTHORS Patowary,A., Won,S.Y., Oh,S.J., Nesbitt,R.R., Archer,M., Nickerson,D., Raskind,W.H., Bernier,R., Lee,J.E. and Brkanac,Z. TITLE Family-based exome sequencing and case-control analysis implicate CEP41 as an ASD gene JOURNAL Transl Psychiatry 9 (1), 4 (2019) PUBMED 30664616 REMARK Publication Status: Online-Only REFERENCE 3 (bases 1 to 1253) AUTHORS Lee,J.E., Silhavy,J.L., Zaki,M.S., Schroth,J., Bielas,S.L., Marsh,S.E., Olvera,J., Brancati,F., Iannicelli,M., Ikegami,K., Schlossman,A.M., Merriman,B., Attie-Bitach,T., Logan,C.V., Glass,I.A., Cluckey,A., Louie,C.M., Lee,J.H., Raynes,H.R., Rapin,I., Castroviejo,I.P., Setou,M., Barbot,C., Boltshauser,E., Nelson,S.F., Hildebrandt,F., Johnson,C.A., Doherty,D.A., Valente,E.M. and Gleeson,J.G. TITLE CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium JOURNAL Nat Genet 44 (2), 193-199 (2012) PUBMED 22246503 REMARK Publication Status: Online-Only COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC072712.1. ##Evidence-Data-START## Transcript exon combination :: BC072712.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## FEATURES Location/Qualifiers source 1..1253 /organism="Danio rerio" /mol_type="mRNA" /db_xref="taxon:7955" /chromosome="25" /map="25" gene 1..1253 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="centrosomal protein 41" /db_xref="GeneID:431741" /db_xref="ZFIN:ZDB-GENE-040704-35" exon 1..72 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" misc_feature 13..15 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="upstream in-frame stop codon" CDS 40..1164 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="testis specific, 14; testis-specific gene A14 protein" /codon_start=1 /product="centrosomal protein of 41 kDa" /protein_id="NP_001002194.1" /db_xref="GeneID:431741" /db_xref="ZFIN:ZDB-GENE-040704-35" /translation="
MSVKRGIGDSAFLKKKIPQNPKYQHVKTRLDTGSSLTKYMERLEEARKNYRYRKDELFKRLKVTTFAQLVIQVASVSDQNDNIKDEMAGLEDDVSIFSASPGLDCLSDQTNGSPQPNLPPPQTINIDESGDNGFSPRSTLQSVISGVGELDLDKNGQKTIRLSPVSTSNTTECPYPDCPYLLLDVRDRELYDQCHIVSAYSYPIATLSRTMNPYTKEVLDYKNASGKIIIVYDEDERIASQAATTMCERGFENLFMLSGGLKVVAQKFPEGMTTGSVPISCLPSPTGPAGRKRSAQHQTSQLAEKKWRFTAEDLDKIQHYLEEVFIPSETSSRLSSRMSTSSARSKASTVGSSRQGSSIAGSESARSRSSRPWK"
misc_feature 568..825 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="Rhodanese-like domain; Region: Rhodanese; pfam00581" /db_xref="CDD:425764" misc_feature 736..738 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="active site residue [active]" /db_xref="CDD:238089" misc_feature 874..942 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="propagated from UniProtKB/Swiss-Prot (Q6GQN0.1); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" misc_feature 1024..1161 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /note="propagated from UniProtKB/Swiss-Prot (Q6GQN0.1); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite" exon 73..136 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 137..184 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 185..246 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 247..313 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 314..464 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 465..634 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 635..702 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 703..817 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 818..1033 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" exon 1034..1229 /gene="cep41" /gene_synonym="tsga14; zgc:91859" /inference="alignment:Splign:2.1.0" ORIGIN
ggtagctaacattagccgccgaagctctgctgctggaagatgtcggtgaagagggggattggcgattcagcgtttttaaagaagaagattcctcagaacccaaaatatcagcatgtaaaaacaaggcttgatacaggctccagcctgacaaaatacatggagagactagaggaggcaagaaaaaactacagatataggaaggacgagttgtttaagagactgaaagtgaccacatttgcacagctggtaatccaagttgcttcggtatcagatcagaatgacaacattaaagatgaaatggcgggattagaagatgatgtttcgatattctctgcatcaccgggcctcgactgtctctccgatcagactaatggctccccacaaccaaaccttcctcctccacagaccatcaacattgacgaatccggcgacaatggcttttctcccagatctacacttcaaagtgtcatcagtggcgtgggagaattagatctggacaagaacggacagaagaccatccggctgtctccggtttctacctccaacaccacagagtgtccctatcccgactgcccatatctgttgctggatgtgcgggacagagagctgtatgaccagtgccatattgtcagtgcgtatagctaccctattgcaaccttatcaaggacgatgaacccgtacacaaaagaagtgcttgactacaaaaatgcatctggaaagatcatcatcgtgtatgacgaggatgagaggatagcaagtcaagcagccactaccatgtgtgaaagaggcttcgagaatcttttcatgctgtcgggggggttaaaagtggttgctcagaagtttccagaaggaatgacgaccggctcagttcccatctcctgtttgccatcaccaacaggccctgcaggacgcaagcgatcagcacagcaccagacatcacagttggcagagaaaaagtggcggttcacagcagaagatcttgacaaaatccagcattaccttgaggaggtgttcatacccagtgaaaccagcagtcgcctcagcagcagaatgtccactagcagcgctcgctccaaagcgtctacagtcggtagcagtcgacaaggttcatccatagcaggatcagaaagtgctcgttcaagaagtagtcgaccctggaaataaccctcgctttcacctggtcacagcttcacttcaatgcataaataaatccatgctgttttactttaaaaaaaaaaaaaaaaaaaaaaaaa
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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