LOCUS       NM_001002131            1448 bp    mRNA    linear   VRT 08-AUG-2023
DEFINITION  Danio rerio proteasome 26S subunit, non-ATPase 8 (psmd8), mRNA.
ACCESSION   NM_001002131
VERSION     NM_001002131.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1448)
  AUTHORS   Tu X, Wang HB, Huang Q, Cai Y, Deng YP, Yong Z, Hu Q, Feng J,
            Jordan JB and Zhong S.
  TITLE     Screening Study on the Anti-Angiogenic Effects of Traditional
            Chinese Medicine - Part II: Wild Chrysanthemum
  JOURNAL   J Cancer 12 (1), 124-133 (2021)
   PUBMED   33391408
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1448)
  AUTHORS   Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A,
            Choudhary JS, Emes RD and Grant SG.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1448)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1448)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX936429.8 and BX908775.18.
            
            On Aug 8, 2023 this sequence version replaced NM_001002131.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC071432.1, GFIL01031643.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA2168446,
                                           SAMEA2168447 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               BX936429.8         149402-149554
            154-226             BX936429.8         151741-151813
            227-329             BX936429.8         151900-152002
            330-495             BX936429.8         153954-154119
            496-596             BX936429.8         154200-154300
            597-708             BX936429.8         154408-154519
            709-827             BX936429.8         156714-156832
            828-1448            BX908775.18        81570-82190         c
FEATURES             Location/Qualifiers
     source          1..1448
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="18"
                     /map="18"
     gene            1..1448
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="proteasome 26S subunit, non-ATPase 8"
                     /db_xref="GeneID:415221"
                     /db_xref="ZFIN:ZDB-GENE-040625-136"
     exon            1..153
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    7..9
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="upstream in-frame stop codon"
     CDS             43..846
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 8"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 8"
                     /protein_id="NP_001002131.1"
                     /db_xref="GeneID:415221"
                     /db_xref="ZFIN:ZDB-GENE-040625-136"
                     /translation="

MASVLKETAGLYETLKAEWNKKNPNLNKCGELLSKLKISLLELNFLPTTGTKLTKQQLILARDVLEIGALWSILKKDIPSFERYMAQLKCYYFDYKDELPESAYRHQLLGLNLLFLLSQNRVSEFHTELERLSAKDIQTNVYIRHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDTLLDTIRDEIAGCIEKAYEQIQFNEATRVLFFSSPKKMTDYAKKRNWTQSPDGYYSFSTQHQKTEEVTIPSTELAKQVIEYARQLEMIV"

     misc_feature    394..738
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /note="CSN8/PSMD8/EIF3K family; Region: CSN8_PSD8_EIF3K;
                     pfam10075"
                     /db_xref="CDD:370807"
     exon            154..226
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            227..329
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            330..495
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            496..596
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            597..708
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
     exon            709..1448
                     /gene="psmd8"
                     /gene_synonym="fa93g07; fb17c09; fb49a10; wu:fa93g07;
                     wu:fb17c09; wu:fb49a10; zgc:86762"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtgttctgacaggccggtgtcgtacatttttgcagaatcaccatggcgtctgtgttgaaagagactgcgggattatatgaaacattgaaagccgagtggaataaaaagaacccaaacctcaataaatgcggtgagctcttgagcaagttaaagatttccctgttggagttgaactttctaccaaccactgggaccaaactaaccaaacagcagcttatcctcgcacgagatgttttggagattggagcgctgtggagcattctgaagaaagacatcccctcatttgaacgctacatggctcagcttaaatgctactactttgattacaaggatgagttgcctgagtcggcctacaggcaccagttgctgggactaaacctgctcttcctgctctctcagaaccgagtgtctgaatttcacacagagctggaaagactgagcgcaaaggacatccagacgaacgtctacatcagacacccagtttcattagagcagtatctgatggagggcagttacaacaaggtatttcttgccaaaggaaatattcccgcggagagctacaccttctttattgatactcttcttgataccatccgagatgagattgcaggttgtatagagaaagcatatgaacagattcaattcaatgaagccacgcgggtgcttttcttttcctctccaaaaaagatgacagactatgcaaagaaaagaaactggacccagagtcctgatggatactactcattcagcacccagcatcaaaagacagaggaggtgaccatcccctccacagaactggccaaacaagtcatcgagtatgcaagacagctggaaatgattgtgtagtgtggatatttgacacatgtatacataaaggttcacatttgttcatccaaacatacaaataaaagcattgtacagtggccatatatctggactcagtttagacagcggatgacacacccacaaataatggatctcagaggcctacgaatgatcaatatctgcctgtatcagggtctcttggtatgattgtgtgttggatgtgtgttttcagtaactctcttgcattactggtgatcatctaataaccgctctaagtttttttggaaataaacatttaatacgtatagtttgaatatcaagttgttttttcccctcaatgtttaatgggttttttttaacaaaagtgagtttgagagtttggaaaagtgggtctagatagtatgttggggatggaagctaaacttcactgcttattcaatgtaatcccaggagtattcattgaattattgtactctccgccttgtatcctagcaactgtgagaggattggttaaaagtttgcagatgtttttctttgtttatcctgtaatgggataaaaatcccccaaattgtcaaaaggaagtgacagttcatagtaaataaaactgttttttctgattctt

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