LOCUS       XM_018814644            2015 bp    mRNA    linear   INV 22-OCT-2018
DEFINITION  PREDICTED: Ciona intestinalis 4-trimethylaminobutyraldehyde
            dehydrogenase (LOC100175707), mRNA.
ACCESSION   XM_018814644
VERSION     XM_018814644.2
DBLINK      BioProject: PRJNA187185
KEYWORDS    RefSeq.
SOURCE      Ciona intestinalis (vase tunicate)
  ORGANISM  Ciona intestinalis
            Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
            Cionidae; Ciona.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_020178.2) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 22, 2018 this sequence version replaced XM_018814644.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Ciona intestinalis Annotation
                                           Release 104
            Annotation Version          :: 104
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.1
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2015
                     /organism="Ciona intestinalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:7719"
                     /chromosome="13"
     gene            1..2015
                     /gene="LOC100175707"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 30 ESTs, 4 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 195 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:100175707"
     CDS             7..1569
                     /gene="LOC100175707"
                     /codon_start=1
                     /product="4-trimethylaminobutyraldehyde dehydrogenase"
                     /protein_id="XP_018670189.1"
                     /db_xref="GeneID:100175707"
                     /translation="

MLSFRLQQLRLLACNSLNKSHRNIIRSVASGTYNVTTPLNFIGGQRVETEESLSIIDVIEPATGKVMCQMHECGATDVNNAVNAAKQAQLEWGKLSGFERGKILSKSSVLLKQKQEEIARMEVYDTGKPIQEARVDVQTAIDSIEYFSGIASTLCGQHFSLPNGSFGYTRREPLGVVAAIGAWNYPIQIAAWKAAPALATGNAVVCKPSQFTPLTAVALAEVFIEGGLPSGLFNVVQGAGETGNHLTRHPDVAKVTFTGSIETGSKVMQNCAADIRHVTLELGGKSPLILFGDCDITNAVNGALMANFLSQGQVCSNGTRVFIQDDIYDEVVTMLVERTLGIKHGDPHHEHTKMGAMMNEEHAHKVMGFIERAKKEGAEVLCGGELVQMEDPVLRGGSYISPCIIRPSDSMEISREELFGPVMNVYSFKTEDEVIRRANDSKYGLASGVFTKDIQRAHRVAASMQAGSCYINNYNIFPIEMPFGGYKKSGLGRENGTVTVDYFTQLKTVYVEMNDVECSL"

     misc_feature    178..1548
                     /gene="LOC100175707"
                     /note="NAD+-dependent 4-trimethylaminobutyraldehyde
                     dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH;
                     cd07090"
                     /db_xref="CDD:143409"
     misc_feature    order(292..294,298..300,310..312,319..321,331..333,
                     340..342,439..441,451..453,472..486,508..510,514..522,
                     799..801,832..834,898..900,907..909,916..921,1018..1020,
                     1063..1065,1360..1371,1378..1383,1387..1389,1396..1398,
                     1402..1413,1417..1422,1444..1446,1450..1452,1462..1464,
                     1468..1470,1477..1479,1483..1485,1519..1536,1540..1545)
                     /gene="LOC100175707"
                     /note="tetrameric interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:143409"
     misc_feature    order(544..549,553..558,625..627,721..723,775..777,
                     781..786,793..795,847..855,949..951,1255..1257,1261..1263,
                     1453..1455)
                     /gene="LOC100175707"
                     /note="NAD binding site [chemical binding]; other site"
                     /db_xref="CDD:143409"
     misc_feature    order(556..558,847..849,940..942,949..951)
                     /gene="LOC100175707"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143409"
ORIGIN      

ggtaaaatgttgtcatttagattgcaacaacttcgtttgttagcttgtaatagtttaaataagtcacatagaaacattatacggagtgtggcaagcggcacctacaatgtgacaaccccactcaactttattggcggacaaagagtcgaaacagaagaatctttgtcaataattgatgtcattgaaccggcaacaggaaaagtaatgtgccagatgcacgaatgtggagctactgacgtaaacaacgcggttaatgctgcaaaacaagctcaacttgaatggggaaaactatcagggttcgaaagagggaaaatattgtcaaagtcttctgttttattaaagcaaaagcaagaagagattgctagaatggaggtctacgatacagggaagccaatacaagaagcgagagttgatgttcaaactgctatcgattctattgagtatttcagtggaattgcttcaactctgtgtggccagcacttttcgttgcctaacgggtcgttcggctacacacgacgtgagccactaggtgtcgtagcagcgataggagcgtggaattacccgatacaaatcgctgcgtggaaagccgcacctgcactcgcaactggcaatgcagttgtatgcaagccatcacaattcacccctttgactgcagttgcgttagctgaagtatttatagaagggggactaccctcaggactttttaatgtggtacagggggctggggagacggggaaccacctaacacgacacccagatgtcgcgaaagttacttttactgggagtattgaaactggaagtaaggttatgcagaattgtgccgcagacataagacatgtcacacttgagcttggaggaaaatctccattgatattgtttggagattgtgacatcactaatgctgtcaatggagcattgatggcaaactttttgtcacaaggacaggtatgctccaatggcacacgtgtgttcatccaagatgatatctatgacgaagtagtaacaatgctagtggagagaacacttgggatcaaacatggcgacccacatcatgaacatacaaagatgggagcaatgatgaatgaagaacacgcacacaaagtcatggggtttattgagagggctaagaaggagggagctgaagtgttatgtggtggggaacttgtgcaaatggaagacccagtgttgcgaggtggaagttatatttccccatgtattattagaccaagtgatagtatggaaatatccagagaggaattgtttgggccagtaatgaacgtttattcgttcaaaactgaagatgaagtcatccgaagagcaaatgactcaaagtatgggctggcttctggggtttttaccaaagacatacagcgagcccacagagttgcggcatcaatgcaagcaggtagttgttacatcaacaactataatatctttccaatagaaatgccatttggtggttataaaaagtctggtctgggaagagagaatggaacagttactgttgattatttcacacaactgaaaacagtttatgttgaaatgaatgatgttgaatgttctttatgattaaacaatcgcaatcattctaaatctcctttaaaagtatattgcagtcatatcaaaatttcctaagctgccaaatctacagtattgtactaagatgccatggaataatattataacttataatattggagggccaaaaatggcacacaaaaagccccatatctaaattgtaacttgtttttgcattataatacttgatttacagttttacacgtttaaaacacattgtgctcttttgaacagttctttggtgctgttttctgtgaaaaaatatgaatatattacaacttttacaccatacagcttatattaatgctaaaaaatgaaaataaattgctaatctagaaactgaactagaaatcggctaatctagaaacaaacactgtgctttataaacatgcgagtaaaaatacaaccatttattctgtgctcagtgcaatgttaat

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