LOCUS       NM_001128872            1315 bp    mRNA    linear   INV 16-AUG-2020
DEFINITION  Ciona intestinalis homeobox transcription factor Hox13 (hox13),
            mRNA.
ACCESSION   NM_001128872
VERSION     NM_001128872.1
KEYWORDS    RefSeq.
SOURCE      Ciona intestinalis (vase tunicate)
  ORGANISM  Ciona intestinalis
            Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
            Cionidae; Ciona.
REFERENCE   1  (bases 1 to 1315)
  AUTHORS   Tajima Y, Hozumi A, Yoshida K, Treen N, Sakuma T, Yamamoto T and
            Sasakura Y.
  TITLE     Hox13 is essential for formation of a sensory organ at the terminal
            end of the sperm duct in Ciona
  JOURNAL   Dev. Biol. 458 (1), 120-131 (2020)
   PUBMED   31682808
  REMARK    GeneRIF: Hox13 is essential for formation of a sensory organ at the
            terminal end of the sperm duct in Ciona.
REFERENCE   2  (bases 1 to 1315)
  AUTHORS   Keys DN, Lee BI, Di Gregorio A, Harafuji N, Detter JC, Wang M,
            Kahsai O, Ahn S, Zhang C, Doyle SA, Satoh N, Satou Y, Saiga H,
            Christian AT, Rokhsar DS, Hawkins TL, Levine M and Richardson PM.
  TITLE     A saturation screen for cis-acting regulatory DNA in the Hox genes
            of Ciona intestinalis
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 102 (3), 679-683 (2005)
   PUBMED   15647365
REFERENCE   3  (bases 1 to 1315)
  AUTHORS   Imai KS, Hino K, Yagi K, Satoh N and Satou Y.
  TITLE     Gene expression profiles of transcription factors and signaling
            molecules in the ascidian embryo: towards a comprehensive
            understanding of gene networks
  JOURNAL   Development 131 (16), 4047-4058 (2004)
   PUBMED   15269171
REFERENCE   4  (bases 1 to 1315)
  AUTHORS   Satou Y and Satoh N.
  TITLE     Genomewide surveys of developmentally relevant genes in Ciona
            intestinalis
  JOURNAL   Dev. Genes Evol. 213 (5-6), 211-212 (2003)
   PUBMED   12736827
REFERENCE   5  (bases 1 to 1315)
  AUTHORS   Spagnuolo A, Ristoratore F, Di Gregorio A, Aniello F, Branno M and
            Di Lauro R.
  TITLE     Unusual number and genomic organization of Hox genes in the
            tunicate Ciona intestinalis
  JOURNAL   Gene 309 (2), 71-79 (2003)
   PUBMED   12758123
REFERENCE   6  (bases 1 to 1315)
  AUTHORS   Satou Y, Yamada L, Mochizuki Y, Takatori N, Kawashima T, Sasaki A,
            Hamaguchi M, Awazu S, Yagi K, Sasakura Y, Nakayama A, Ishikawa H,
            Inaba K and Satoh N.
  TITLE     A cDNA resource from the basal chordate Ciona intestinalis
  JOURNAL   Genesis 33 (4), 153-154 (2002)
   PUBMED   12203911
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB210493.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB210493.1, BW342903.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028078, SAMD00028079
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1315
                     /organism="Ciona intestinalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:7719"
                     /chromosome="7"
                     /map="7"
     gene            1..1315
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /note="homeobox transcription factor Hox13"
                     /db_xref="GeneID:100169888"
     exon            1..146
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    68..70
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /note="upstream in-frame stop codon"
     CDS             92..550
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /note="putative homeobox protein Hox12/13"
                     /codon_start=1
                     /product="homeobox transcription factor Hox13"
                     /protein_id="NP_001122344.1"
                     /db_xref="GeneID:100169888"
                     /translation="

MRNVRTAYVMTVSAYCCAALGLQHGPSHSRKKRQPYSKTQISSLEREYKANNFITRQKRENIARDLKLSDRQVKIWFQNRRVKDKKIKQREIKDNQQHHQTTELQRRDSHTQKQEMYQRHSAMIPIEMKNEHIRIDHIHSHVPGLGSASILM"

     misc_feature    order(179..193,197..199,248..250,266..268,305..307,
                     311..316,323..328,332..340,344..349)
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    185..346
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(185..187,194..196,314..316,323..328,335..337)
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            147..382
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /inference="alignment:Splign:2.1.0"
     exon            383..1293
                     /gene="hox13"
                     /gene_synonym="Ci-Hox13; hox12/13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gccatattaagttactaataaatgttagaggtaatttaacggcagcggtgctctctcgtctgcagtttgatcgaaaggcgtatccagttcaatgcgaaacgtccgtaccgcatacgtaatgactgtaagcgcatattgctgtgcagcgctaggtcttcaacatggaccatcacattctcggaagaaacgccagccttacagcaaaacccagatcagcagccttgagcgtgagtacaaagcaaacaacttcataacgcgacagaaaagagaaaacattgcaagagacctgaagctttctgaccgccaagtcaaaatttggtttcaaaatcgacgtgttaaagataagaagataaagcaacgcgaaataaaagacaaccagcagcaccaccagacgacggagttgcagcgacgagacagccacacacaaaaacaagagatgtaccaacgtcacagtgcaatgattccaatcgaaatgaagaacgaacacattcgaatcgaccacattcactcgcacgttccaggtcttggatcagcctctatactaatgtaaactaaaagagtcatttcaaaacctttgtgcttttatttcaccactgcaacggtctccggccaaaactcgatgtgcatctttctcaatgcaatcttttttcgtttacacaaaccacatggctttacacaattgtaacatatatacttgaacttaaacttcaattatcttccatttggatccgcgcatagtatattgctgtgattatcgtctccatgttggcgtaagagctgtgtatccgcacatctttacattttacaatcagttttatttacgtactgtcgttacattttgtatatttttgtccctagttccatttttctttacattatgtttcatgtgctgcattttcatttaagctggtaggattcttaggacaactatagtaccttgggggtaagataccctttctcaaataatatcctgatcatgttttaaacaattaacaacgccccatgtgagtcgtaaggatacagtttcatatttctttgaatcctctttgttacgatcaaataggactagaaaatagaatgaaaagatttcccttcttcccccaccatactgtgtatgagttgccactcaatatttctctgagaggtcggttgtttaccggcaaaacaaatcctaatccaatgatacatttacctgtaacactatcgacatatcaaattttaatttagcattagtattgaaacatggttttatataagtgcatgcgaagataaattacacaaaaaaagagcatgataaaaaaaaaaaaaaaaaaaa

//