LOCUS       NM_001032495            2297 bp    mRNA    linear   INV 04-MAY-2019
DEFINITION  Ciona intestinalis homeobox transcription factor TTF1 (titf1),
            mRNA.
ACCESSION   NM_001032495
VERSION     NM_001032495.1
KEYWORDS    RefSeq.
SOURCE      Ciona intestinalis (vase tunicate)
  ORGANISM  Ciona intestinalis
            Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
            Cionidae; Ciona.
REFERENCE   1  (bases 1 to 2297)
  AUTHORS   Satou Y, Kawashima T, Shoguchi E, Nakayama A and Satoh N.
  TITLE     An integrated database of the ascidian, Ciona intestinalis: towards
            functional genomics
  JOURNAL   Zool. Sci. 22 (8), 837-843 (2005)
   PUBMED   16141696
REFERENCE   2  (bases 1 to 2297)
  AUTHORS   Imai KS, Hino K, Yagi K, Satoh N and Satou Y.
  TITLE     Gene expression profiles of transcription factors and signaling
            molecules in the ascidian embryo: towards a comprehensive
            understanding of gene networks
  JOURNAL   Development 131 (16), 4047-4058 (2004)
   PUBMED   15269171
REFERENCE   3  (bases 1 to 2297)
  AUTHORS   Satou Y and Satoh N.
  TITLE     Genomewide surveys of developmentally relevant genes in Ciona
            intestinalis
  JOURNAL   Dev. Genes Evol. 213 (5-6), 211-212 (2003)
   PUBMED   12736827
REFERENCE   4  (bases 1 to 2297)
  AUTHORS   Satou Y, Yamada L, Mochizuki Y, Takatori N, Kawashima T, Sasaki A,
            Hamaguchi M, Awazu S, Yagi K, Sasakura Y, Nakayama A, Ishikawa H,
            Inaba K and Satoh N.
  TITLE     A cDNA resource from the basal chordate Ciona intestinalis
  JOURNAL   Genesis 33 (4), 153-154 (2002)
   PUBMED   12203911
REFERENCE   5  (bases 1 to 2297)
  AUTHORS   Ristoratore F, Spagnuolo A, Aniello F, Branno M, Fabbrini F and Di
            Lauro R.
  TITLE     Expression and functional analysis of Cititf1, an ascidian NK-2
            class gene, suggest its role in endoderm development
  JOURNAL   Development 126 (22), 5149-5159 (1999)
   PUBMED   10529431
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ009607.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ009607.1, AB210735.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00028078, SAMD00028079
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2297
                     /organism="Ciona intestinalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:7719"
                     /chromosome="10"
                     /map="10"
     gene            1..2297
                     /gene="titf1"
                     /gene_synonym="Ci-TTF1; TTF1"
                     /note="homeobox transcription factor TTF1"
                     /db_xref="GeneID:445676"
     misc_feature    15..17
                     /gene="titf1"
                     /gene_synonym="Ci-TTF1; TTF1"
                     /note="upstream in-frame stop codon"
     CDS             72..1505
                     /gene="titf1"
                     /gene_synonym="Ci-TTF1; TTF1"
                     /function="transcription factor"
                     /codon_start=1
                     /product="homeobox transcription factor TTF1"
                     /protein_id="NP_001027667.1"
                     /db_xref="GeneID:445676"
                     /translation="

MSVSPKHSTTTPFSVTDILSPLEESYGTGSVEGIVSGRREFSELYSNMESGAASSAGIHVPNLGGGGSTGSISSPMTSYRQPMMGTPPHHSIHHQQMSSANPYQTAAGMNGSYNLHPMPTPPQTSFHAMPGSGGPTPYGNGGVPELPPYNNVQSPWYGAPSNPDPRFVPSYPRLQITGYGSMMPGTGMDGMHKTLLPPSQRRKRRVLFSQAQVFELERRFKQQKYLSAPEREHLAQMIHLTPTQVKIWFQNHRYKNKRSLKDKQTQEMSVQQQQQQQQQSQTSGNAQPQHTNDLSHSNPSQLQPVASAVPGGTRTPQETYSPVPTGVQASQPGMVDGNDGHRMVHISNQNGDQSSPRHLTMSDGSCHDSTIIESPNMQMPMPNVVQPTDTEAGLGPFSSVIKLEEVNADSAEGSGGNSGNIVPQTHYLGSTHHHDLMNVNVTTLNAVDAYQHHPHHNHIPIGNTVLNDQSILYSVYR"

     misc_feature    672..842
                     /gene="titf1"
                     /gene_synonym="Ci-TTF1; TTF1"
                     /note="Homeodomain; Region: HOX; smart00389"
                     /db_xref="CDD:197696"
     misc_feature    order(675..689,693..695,744..746,762..764,801..803,
                     807..812,819..824,828..836,840..845)
                     /gene="titf1"
                     /gene_synonym="Ci-TTF1; TTF1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(681..683,690..692,810..812,819..824,831..833)
                     /gene="titf1"
                     /gene_synonym="Ci-TTF1; TTF1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
ORIGIN      

ggttttaagtcaattaatatttaatcctgcaagttaataatttattccgacactggagactttgctgtgagatgtcagttagcccaaagcattcgactacaaccccattttcagttaccgatattttgagtccgctagaagagtcgtacgggaccggttcggttgaaggcattgtcagcggccgcagggaatttagcgagctgtacagcaacatggaatccggcgcggcctcgtcggcgggaattcacgtcccgaatctcggcgggggaggcagcacggggtcgatctcttcccccatgacttcgtaccgacaaccgatgatgggcacgccgccgcaccattctatacaccatcagcaaatgtcatctgccaacccttaccagactgcagcaggaatgaatggaagttataacctgcaccctatgcctaccccaccgcaaacctcgtttcatgcaatgcctggatctggtggaccgactccctatggcaacgggggtgttccggagctgccaccgtataataatgtacaatctccatggtacggtgcaccttcaaatccagacccaagatttgtcccaagttaccctcgtttgcaaattactggttatggttctatgatgccaggtacaggcatggatggaatgcacaagacgcttctgccaccatctcagagaagaaaacgaagggttctgttttcccaagcacaggtgtttgaactagagagacgtttcaagcaacagaaatatctctccgctcctgaaagggaacacctggcacaaatgatacatcttacgccaacgcaggttaaaatttggtttcaaaatcaccggtacaaaaacaaacgttcactaaaagacaagcaaacgcaagaaatgagtgtacaacaacaacaacaacagcaacagcagtcccagacctctggtaacgcgcaacctcagcacacaaacgatctgtctcactcgaatcctagccagctccagcccgtagccagtgctgtaccgggcggaacacggacgccacaagaaacgtattcccctgttccaactggtgtccaggcttctcagccaggtatggtggatggaaacgatgggcataggatggttcacatttcgaaccagaacggtgaccagtcttcgccgcgccatttaaccatgtcagatggttcttgccacgattcgacgatcatcgagtcgccaaacatgcaaatgccgatgccgaacgtcgtgcaaccgaccgacaccgaagcaggccttgggccgttttcaagcgtcataaaactcgaagaagtaaacgctgactcggcggaagggtccggcgggaactcgggcaacatcgtcccgcagacgcactaccttggctcgacccaccaccacgacctaatgaacgtgaacgtgacgacacttaatgcggtcgacgcgtaccaacaccacccccaccataaccacatccctatcggcaacactgtcttgaacgatcagtcgatcctgtacagtgtttaccgatgaattagcaactgaacgtacgcctcttatgataaggctgtctcaatgctatagaagcgaaggttagaggcagtagtagaactataagtgtcaacataacacaatgactcatagttacgtacgcagggtcttctattagtcgttttacttctacaaatacaccgctatacttaagcatacatattacacaagttatacctgattcgacgtacttctgtttatacgtacttatgtcagactaatccgaaactcatttaattcaacttaaacattcaagtcgaaagtcgtcgaagccgacactgttccgatagtacactgtataattcacttgagcagtccacatcgattgcgatatagccgcatcgtcaagactacttaccagggcttccagtacctcctcatataatacttaatagactcagcagtcctgaacgacagtaattatgaatggggaaaacaccatacggggttaccactgatcttaatacagtttttgacgaacagcaatcatatcttattattgagaaaaaatggcgccaattttaggcggttattgccaatgtctactgaagcgtgacgttgaaggtgaaatgttgtttctattctccattcaaatatgtgttatcttcatatataccgtgatgtattatttgaattaggtgcaacgcttttgaggtcaacgatgtttctttgcgcgccttttgtattttacctatccatgtcacactttgttaccttttaggcgccctgtacatattattcaccaaataaatcatctctaccgaaaaaaaaaaa

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