LOCUS       NM_123358                697 bp    mRNA    linear   PLN 20-OCT-2022
DEFINITION  Arabidopsis thaliana thioredoxin 2 (TRX2), mRNA.
ACCESSION   NM_123358
VERSION     NM_123358.4
DBLINK      BioProject: PRJNA116
            BioSample: SAMN03081427
KEYWORDS    RefSeq.
SOURCE      Arabidopsis thaliana (thale cress)
  ORGANISM  Arabidopsis thaliana
            Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
            Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
            Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
            Camelineae; Arabidopsis.
REFERENCE   1  (bases 1 to 697)
  AUTHORS   Tabata,S., Kaneko,T., Nakamura,Y., Kotani,H., Kato,T., Asamizu,E.,
            Miyajima,N., Sasamoto,S., Kimura,T., Hosouchi,T., Kawashima,K.,
            Kohara,M., Matsumoto,M., Matsuno,A., Muraki,A., Nakayama,S.,
            Nakazaki,N., Naruo,K., Okumura,S., Shinpo,S., Takeuchi,C., Wada,T.,
            Watanabe,A., Yamada,M., Yasuda,M., Sato,S., de la Bastide,M.,
            Huang,E., Spiegel,L., Gnoj,L., O'Shaughnessy,A., Preston,R.,
            Habermann,K., Murray,J., Johnson,D., Rohlfing,T., Nelson,J.,
            Stoneking,T., Pepin,K., Spieth,J., Sekhon,M., Armstrong,J.,
            Becker,M., Belter,E., Cordum,H., Cordes,M., Courtney,L.,
            Courtney,W., Dante,M., Du,H., Edwards,J., Fryman,J., Haakensen,B.,
            Lamar,E., Latreille,P., Leonard,S., Meyer,R., Mulvaney,E.,
            Ozersky,P., Riley,A., Strowmatt,C., Wagner-McPherson,C., Wollam,A.,
            Yoakum,M., Bell,M., Dedhia,N., Parnell,L., Shah,R., Rodriguez,M.,
            See,L.H., Vil,D., Baker,J., Kirchoff,K., Toth,K., King,L.,
            Bahret,A., Miller,B., Marra,M., Martienssen,R., McCombie,W.R.,
            Wilson,R.K., Murphy,G., Bancroft,I., Volckaert,G., Wambutt,R.,
            Dusterhoft,A., Stiekema,W., Pohl,T., Entian,K.D., Terryn,N.,
            Hartley,N., Bent,E., Johnson,S., Langham,S.A., McCullagh,B.,
            Robben,J., Grymonprez,B., Zimmermann,W., Ramsperger,U., Wedler,H.,
            Balke,K., Wedler,E., Peters,S., van Staveren,M., Dirkse,W.,
            Mooijman,P., Lankhorst,R.K., Weitzenegger,T., Bothe,G., Rose,M.,
            Hauf,J., Berneiser,S., Hempel,S., Feldpausch,M., Lamberth,S.,
            Villarroel,R., Gielen,J., Ardiles,W., Bents,O., Lemcke,K.,
            Kolesov,G., Mayer,K., Rudd,S., Schoof,H., Schueller,C.,
            Zaccaria,P., Mewes,H.W., Bevan,M. and Fransz,P.
  CONSRTM   Kazusa DNA Research Institute; Cold Spring Harbor and Washington
            University in St Louis Sequencing Consortium; European Union
            Arabidopsis Genome Sequencing Consortium
  TITLE     Sequence and analysis of chromosome 5 of the plant Arabidopsis
            thaliana
  JOURNAL   Nature 408 (6814), 823-826 (2000)
   PUBMED   11130714
REFERENCE   2  (bases 1 to 697)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 697)
  AUTHORS   Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
            Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
            Vaughn,M. and Town,C.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
            9704 Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Protein update by submitter
REFERENCE   4  (bases 1 to 697)
  AUTHORS   Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
  CONSRTM   TAIR
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
            Institution, 260 Panama Street, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
            This record is derived from an annotated genomic sequence
            (NC_003076).
            
            On Sep 12, 2016 this sequence version replaced NM_123358.3.
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Arabidopsis thaliana"
                     /mol_type="mRNA"
                     /db_xref="taxon:3702"
                     /chromosome="5"
                     /ecotype="Columbia"
     gene            1..697
                     /gene="TRX2"
                     /locus_tag="AT5G39950"
                     /gene_synonym="Arabidopsis thioredoxin h2; ATH2; ATTRX2;
                     ATTRXH2; MYH19.110; MYH19_110; THIOREDOXIN; thioredoxin 2;
                     THIOREDOXIN H2; TRXH2"
                     /note="encodes a cytosolic thioredoxin that reduces
                     disulfide bridges of target proteins by the reversible
                     formation of a disulfide bridge between two neighboring
                     Cys residues present in the active site. Thioredoxins have
                     been found to regulate a variety of biological reactions
                     in prokaryotic and eukaryotic cells."
                     /db_xref="Araport:AT5G39950"
                     /db_xref="GeneID:833992"
                     /db_xref="TAIR:AT5G39950"
     CDS             98..499
                     /gene="TRX2"
                     /locus_tag="AT5G39950"
                     /gene_synonym="Arabidopsis thioredoxin h2; ATH2; ATTRX2;
                     ATTRXH2; MYH19.110; MYH19_110; THIOREDOXIN; thioredoxin 2;
                     THIOREDOXIN H2; TRXH2"
                     /inference="Similar to RNA sequence,
                     EST:INSD:ES028931.1,INSD:DR306666.1,INSD:DR319589.1,
                     INSD:EH822474.1,INSD:BP823203.1,INSD:EL184925.1,
                     INSD:EH951383.1,INSD:BP861002.1,INSD:DR319590.1,
                     INSD:DR319607.1,INSD:DR319611.1,INSD:EG457699.1,
                     INSD:DR319618.1,INSD:BP653143.1,INSD:BP868978.1,
                     INSD:DR319586.1,INSD:ES049470.1,INSD:EL098702.1,
                     INSD:EL282446.1,INSD:DR186386.1,INSD:BP655296.1,
                     INSD:EL286657.1,INSD:EL218603.1,INSD:EL237153.1,
                     INSD:ES011538.1,INSD:EH985614.1,INSD:ES009419.1,
                     INSD:ES135292.1,INSD:AV813766.1,INSD:BP622008.1,
                     INSD:BP627812.1,INSD:DR361084.1,INSD:ES207590.1,
                     INSD:DR240842.1,INSD:AV790184.1,INSD:DR319610.1,
                     INSD:AV823064.1,INSD:BP819308.1,INSD:ES120895.1,
                     INSD:DR371264.1,INSD:ES178060.1,INSD:DR319616.1,
                     INSD:CD530231.1,INSD:DR319609.1,INSD:CK121279.1,
                     INSD:EL324042.1,INSD:EL048513.1,INSD:DR319606.1,
                     INSD:DR319619.1,INSD:DR319592.1,INSD:DR319595.1,
                     INSD:EL074135.1,INSD:ES030032.1,INSD:CD531265.1,
                     INSD:EL329472.1,INSD:DR319612.1,INSD:BP845103.1,
                     INSD:DR319596.1,INSD:CD531294.1,INSD:DR240843.1,
                     INSD:DR319604.1,INSD:DR319608.1,INSD:DR306668.1,
                     INSD:DR319587.1,INSD:DR319602.1,INSD:EH921884.1,
                     INSD:DR353268.1,INSD:EG419593.1,INSD:ES204466.1,
                     INSD:BP637392.1,INSD:DR319614.1,INSD:BP646058.1,
                     INSD:EH881250.1,INSD:DR319600.1,INSD:BP641909.1,
                     INSD:BP623480.1,INSD:AI999303.1,INSD:EL202093.1,
                     INSD:EH918298.1,INSD:ES197508.1,INSD:DR306665.1,
                     INSD:ES077032.1,INSD:ES167893.1,INSD:BP624034.1,
                     INSD:DR319588.1,INSD:DR379059.1,INSD:BP591556.1,
                     INSD:ES203985.1,INSD:DR382632.1,INSD:AV783968.1,
                     INSD:BP622625.1,INSD:DR319598.1,INSD:DR319613.1,
                     INSD:BP571803.1,INSD:ES212506.1,INSD:DR319599.1,
                     INSD:BP841774.1,INSD:EH878483.1,INSD:EL207711.1,
                     INSD:BP847750.1,INSD:BP844697.1,INSD:DR240841.1,
                     INSD:EL145744.1,INSD:DR319601.1,INSD:DR319617.1,
                     INSD:BP635096.1,INSD:EL089354.1,INSD:BP863847.1,
                     INSD:EL062116.1,INSD:ES075573.1,INSD:ES113791.1,
                     INSD:BP637157.1,INSD:BP631127.1,INSD:DR380777.1,
                     INSD:EG500651.1,INSD:EH933084.1,INSD:DR240840.1,
                     INSD:ES200589.1,INSD:DR319615.1,INSD:DR306664.1,
                     INSD:EG527088.1,INSD:EH867008.1,INSD:EL184389.1,
                     INSD:DR319593.1,INSD:DR306669.1,INSD:EG432074.1,
                     INSD:EG500648.1,INSD:ES148555.1,INSD:DR319603.1,
                     INSD:DR319597.1,INSD:BP667520.1,INSD:EL297620.1,
                     INSD:BP611127.1,INSD:DR240844.1,INSD:CK121809.1,
                     INSD:ES008161.1,INSD:CB074346.1,INSD:AV532488.1,
                     INSD:DR306667.1,INSD:ES169193.1,INSD:DR372400.1,
                     INSD:EH972907.1,INSD:EH903556.1,INSD:BP854335.2,
                     INSD:EH892468.1,INSD:EL997487.1,INSD:DR372345.1,
                     INSD:EL314388.1,INSD:EG457700.1,INSD:EG527099.1,
                     INSD:BP853128.1,INSD:EL984706.1,INSD:ES152732.1,
                     INSD:BP633327.1,INSD:EH893162.1,INSD:EG521972.1,
                     INSD:BP843306.1,INSD:Z18522.1,INSD:EL217630.1,
                     INSD:EG440572.1,INSD:DR319591.1,INSD:DR319605.1,
                     INSD:BP662452.1,INSD:DR319594.1"
                     /inference="similar to RNA sequence,
                     mRNA:INSD:AY048235.1,INSD:AY088552.1,INSD:BX833912.1,
                     INSD:AY113052.1,INSD:Z35475.1"
                     /note="thioredoxin 2 (TRX2); FUNCTIONS IN: oxidoreductase
                     activity, acting on sulfur group of donors, disulfide as
                     acceptor; INVOLVED IN: N-terminal protein myristoylation,
                     sulfate assimilation; LOCATED IN: cytosol, plasma
                     membrane; EXPRESSED IN: 24 plant structures; EXPRESSED
                     DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s:
                     Thioredoxin fold (InterPro:IPR012335), Thioredoxin, core
                     (InterPro:IPR015467), Thioredoxin domain
                     (InterPro:IPR013766), Thioredoxin, conserved site
                     (InterPro:IPR017937), Thioredoxin-like subdomain
                     (InterPro:IPR006662), Thioredoxin-like
                     (InterPro:IPR017936), Thioredoxin-like fold
                     (InterPro:IPR012336); BEST Arabidopsis thaliana protein
                     match is: thioredoxin H-type 7 (TAIR:AT1G59730.1); Has
                     19714 Blast hits to 19583 proteins in 2950 species: Archae
                     - 262; Bacteria - 11021; Metazoa - 1828; Fungi - 880;
                     Plants - 1790; Viruses - 14; Other Eukaryotes - 3919
                     (source: NCBI BLink)."
                     /codon_start=1
                     /product="thioredoxin 2"
                     /protein_id="NP_198811.1"
                     /db_xref="GeneID:833992"
                     /db_xref="TAIR:AT5G39950"
                     /db_xref="Araport:AT5G39950"
                     /translation="

MGGALSTVFGSGEDATAAGTESEPSRVLKFSSSARWQLHFNEIKESNKLLVVDFSASWCGPCRMIEPAIHAMADKFNDVDFVKLDVDELPDVAKEFNVTAMPTFVLVKRGKEIERIIGAKKDELEKKVSKLRA"

     misc_feature    212..481
                     /gene="TRX2"
                     /locus_tag="AT5G39950"
                     /gene_synonym="Arabidopsis thioredoxin h2; ATH2; ATTRX2;
                     ATTRXH2; MYH19.110; MYH19_110; THIOREDOXIN; thioredoxin 2;
                     THIOREDOXIN H2; TRXH2"
                     /note="TRX family; composed of two groups: Group I, which
                     includes proteins that exclusively encode a TRX domain;
                     and Group II, which are composed of fusion proteins of TRX
                     and additional domains. Group I TRX is a small ancient
                     protein that alter the redox...; Region: TRX_family;
                     cd02947"
                     /db_xref="CDD:239245"
     misc_feature    order(272..274,281..283)
                     /gene="TRX2"
                     /locus_tag="AT5G39950"
                     /gene_synonym="Arabidopsis thioredoxin h2; ATH2; ATTRX2;
                     ATTRXH2; MYH19.110; MYH19_110; THIOREDOXIN; thioredoxin 2;
                     THIOREDOXIN H2; TRXH2"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239245"
ORIGIN      

gcacgatgtttgaatattaaacgacacgatcgttgaccaaagaaagcagggtcgttcttaaacgcaatcagagagagaagcgagacgagagacgataatgggaggagctttatcaactgtgtttggaagtggagaagatgcaacagctgcagggaccgaatctgagccaagtcgcgtcctaaagtttagctcttccgctcggtggcaacttcatttcaacgagatcaaagaatcaaacaaactgctggtggttgatttctcggcctcatggtgcggaccatgtaggatgattgagcctgcgattcatgccatggctgataagttcaatgatgttgatttcgtcaaattagatgttgatgaacttcctgatgtggctaaagagtttaatgtgacggcaatgcctacctttgtgctggtgaaaaggggtaaagaaattgaaagaatcattggtgccaaaaaggacgaacttgagaagaaagttagcaaactcagagcataatgagcattgttaacgccttaaccaatagtcttgtgtaaactcaataataaatggtatgtttatggggaatgtgatgttctatactctctgctaatgtaagaccttctgtgtgatgccatgattgattgaaatggtttgttgaaatgcttagactctgctttcagtggtttatgatacaaagttgacaccttttcagct

//