LOCUS       XM_078352516            7014 bp    mRNA    linear   PRI 01-JAN-2026
DEFINITION  PREDICTED: Callithrix jacchus ATPase copper transporting beta
            (ATP7B), transcript variant X15, mRNA.
ACCESSION   XM_078352516
VERSION     XM_078352516.1
DBLINK      BioProject: PRJNA1262967
KEYWORDS    RefSeq.
SOURCE      Callithrix jacchus (white-tufted-ear marmoset)
  ORGANISM  Callithrix jacchus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_133502) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_049354715.1-RS_2025_12
            Annotation Pipeline         :: NCBI Eukaryotic Genome Annotation
                                           Pipeline (EGAP)
            Annotation Software Version :: 10.5
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/15/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7014
                     /organism="Callithrix jacchus"
                     /mol_type="mRNA"
                     /isolate="240"
                     /db_xref="taxon:9483"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="fibroblast cell line"
                     /geo_loc_name="USA: Pittsburgh"
                     /collection_date="2023-08-31"
     gene            1..7014
                     /gene="ATP7B"
                     /note="ATPase copper transporting beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1086 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 20 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:100384908"
     misc_feature    1
                     /gene="ATP7B"
                     /experiment="COORDINATES: cap analysis [ECO:0007248]"
                     /note="transcription start site"
     CDS             743..4999
                     /gene="ATP7B"
                     /codon_start=1
                     /product="copper-transporting ATPase 2 isoform X11"
                     /protein_id="XP_078208642.1"
                     /db_xref="GeneID:100384908"
                     /translation="

MPKQERHITAREGASRKMLSKLSLPTHAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVTTSTIRILGMTCQSCVKSIEDRISSLKGIVSVKVSVEQGSATVNYVPSVLSPQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKNKVAPLSLGPIDIERLQSTYPKRLFTSANQNINNSETLGNQGNHVVTLQLRIDGMHCTSCILSIEENIGQLPGIQSIQVSLENKTAQVQYDPSCTSPVSLQRAIEALPPGNFKVSLPDGAEGCGTDHGPFSCHSPGFSQRNQVQGTCSTTVIAIAGMTCASCVHSIEGMISQREGVQQISVSLAEGTGTVLYNPSVISPEELSSAIEDMGFEASVISENCSTNSLGNHSAGNSMVQTIGGVPVSVQEVAPHAGGLPTIHTPDILAKSPQSTRAVAPQKCFLQIKGMTCASCISTIERNLQNKAGILSVLVALMAGKAEIKYDPEVVQPLEIAQLIQDLGFEAAVMEDYTGSDGSIELIEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSSEPHESMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQAVEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGAVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFDVVQKYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDMATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHGGHPPSASHLNEAGSLSEGKGCCHRRCLLDAAPQTFSVLIGNREWLRRNGLTISNDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPELERYEAQVHGRIKPLTASQVSVHIGMDDRRRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSATVDDGGDKWSLLLNDRDEEQYI"

     misc_feature    923..1114
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(941..949,956..958)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1178..1369
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1196..1204,1211..1213)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1520..1696
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1538..1546,1553..1555)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1826..2017
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1844..1852,1859..1861)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2216..2404
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(2231..2239,2246..2248)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2534..4663
                     /gene="ATP7B"
                     /note="P-type heavy metal-transporting ATPase, similar to
                     human copper-transporting ATPases, ATP7A and ATP7B;
                     Region: P-type_ATPase_Cu-like; cd02094"
                     /db_xref="CDD:319783"
     misc_feature    order(3527..3529,3533..3535,4592..4594)
                     /gene="ATP7B"
                     /note="putative Cu binding site [ion binding]; other site"
                     /db_xref="CDD:319783"
     misc_feature    order(3659..3667,3869..3871,4043..4051,4139..4141,
                     4259..4267,4325..4327,4334..4336,4343..4345,4400..4402,
                     4409..4411)
                     /gene="ATP7B"
                     /note="putative ATP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:319783"
     polyA_site      7014
                     /gene="ATP7B"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cccccactggaagcccccgcctgggcgtccgcgcccccgtccccggccgagagtccgccgccggttggaggccagtggctgacctttgcgcaccacggatcgattttccaggtgcggagttcactctcgccgcggttgctccctttgggatccgcggccctcggcagccaggctcagagtccgaggaggggcggcgcagagcggacccgttgcgtcgccacccggcaccttccctgcaggcgttgggcgagctctgggagctgcgtctgcggccgggttctgcaccgctcacctgcccttccgctccagcacacgcctgagatcccaggaccgcgtcggagcgcaccagcgcaaggtggccaagaccgcggacctggactggcttccctgtggcgccggcacggccgaggacactgaggcaccagcggggccggcagctccagggcaggcactgccagtccccgagggagtgggtgagagtccgaggcccactcttcccgcgtccgcaggtcgggaggacggcggcgcgcaactttgaaacacccttgtggctagggcagcacgttgcccagtcccaaatgaacgggcggtgcccggaccccttcttgcattagagccgcgccgacgccctcacgcccagcgcctactctccccgtggttttataccgcgctctcctccacggacctggtgacctttggctctgagccggatcagagaagaattccgtgtccgcgcgggaggatgcctaagcaggagagacacatcacagccagagaaggggccagtcggaaaatgttatctaaactttctttgcctacccatgcctgggaaccagcaatgaagaagagttttgcttttgacaatgttggctatgaaggtggtctggatggcctgggcccttcttctcaggtgacgaccagcacaatcaggatcttgggcatgacttgccagtcatgtgtgaagtccattgaggataggatttccagtttgaaaggcattgtgagtgttaaggtttctgtggagcaaggcagtgccactgtgaactatgtgccatcggttttgagcccacaacaggtttgtcatcaaattggggacatgggcttcgaggccagcattgcagaaggaaaggcagcctcctggccctcaaggtccttgcctgcccaggaggctgtggtcaagctccgggtagagggcatgacctgccagtcctgtgtcagctccattgaaggtaaggtccggaaactgcaaggagtagtgagagtcaaagtctcactcagcaaccaagaggctgtcatcacctatcagccttatctcattcagcccgaagacctcagggaccatgtaaacgacatgggatttgaggctgccatcaagaacaaagtggctcccttaagcctgggaccaattgatattgagcggttacaaagcacttacccaaagagacttttcacttctgctaaccagaatattaataattctgagaccttggggaaccaaggaaaccatgtggtcaccctccaactgagaatagatggaatgcactgtacatcttgcatcttgagtattgaagaaaatattggccagctcccagggattcaaagtattcaagtgtccttggagaacaaaactgcccaagtacagtatgacccttcttgtaccagcccggtgtctctgcagagggctatcgaagcacttccacctgggaactttaaagtttctcttcctgatggagcagaagggtgtgggacagatcacgggccttttagttgtcattcccctggcttctcccaaagaaaccaggtgcagggcacgtgcagtaccactgtgattgccattgctggcatgacctgtgcgtcctgtgtccattccatcgaaggcatgatctcccagcgggaaggggtgcagcaaatatcagtctctttggccgaagggactggaacagttctttataatccctccgtaattagcccagaagaactcagctctgctatagaagacatgggatttgaggcttcagtcatttctgaaaactgttccaccaactctcttggaaaccacagtgctgggaattccatggtgcaaactataggtggtgtacctgtatctgtgcaggaagtggctccccatgctggggggctccctaccattcataccccggacatcttggcaaagtccccacaatcaaccagagcagtggcaccacagaagtgcttcttacagatcaaaggcatgacctgtgcatcctgcatatctaccatagaaaggaatctgcagaataaagctggtattctctccgtgttggttgccttgatggcaggaaaggcagagatcaagtatgatccagaggtcgtccagccactcgagatagctcagctcatccaggacctgggctttgaggctgcagtcatggaggactacacaggctccgatggcagcattgagctgattgaaattggctttcatgcttccctggcccagagaaaccccaacgctcatcacttggaccacaagatggaaataaagcagtggaagaagtccttcctgtgcagcctggtgtttggcatccctgtcatggctttaatgatctatatgctcatacccagcagtgagccccatgagtctatggtcctggaccacaacatcattccaggactgtccattctaaatctcatcttctttatcctgtgtaccttcgtccagctcctcggtgggtggtacttctatgttcaggcctacaaatctctgagacacaggtcagccaacatggacgtgctcatcgtcctggccacaagcattgcctacgtctattctctggtcatcctggtggttgctgtggccgagaaggcggagaggagccctgtgacattctttgacacgccccccatgctcttcgtgttcattgccctggggcggtggctggaacacttggcaaagagcaaaacctcagaagcccttgccaaactcatgtctctccaagctgtagaagccactgttgtgacccttggtgaggacaatttaatcatcagggaggagcaagtccccatggagctggtgcagcggggcgatatcgtcaaggtggtccccgggggaaagttcccagtggacgggaaagtcctggaaggcaataccatggctgatgaatccctcatcacaggtgaagccatgccagtcactaagaaacccggaagcactgtaattgcagggtctataaatgcacatggtgctgtgctcattaaagccacccacgtgggcaatgacaccactttggctcagattgtgaaattggtggaagaggcccagatgtcaaaggcacccattcagcaactggctgaccggtttagtggatattttgtcccatttatcatcatcatgtcaactttgacgttggtggtatggattgtaatcggttttatcgattttgatgttgttcagaaatactttcctaaccccaacaagcacatctcccagacggaggtgatcatccggtttgcattccagacgtccatcacagtgctgtgcatcgcctgtccctgttccctggggctggccacgcccacagctgtcatggtgggcactggggtggctgcacagaatggcatcctcatcaagggaggcaagcccctggagatggcgcacaagataaagactgtgatgtttgacaagactggcaccattacccatggggtccccagggtcatgcgggtgctcctgctgggggacatggccacactgcccctcaggaaggttctggctgtggtggggactgcagaggccagcagtgaacaccccttgggcgtggcagtcaccaaatactgtaaagaggaacttggaacagagaccttgggatactgcacagacttccaggcagtgccaggctgtggaatcgggtgcaaagtcagcaacgtggaaggcatcctggcccacggtggacaccctccgagtgccagtcacctgaatgaggctggcagcctttccgaaggaaaaggatgctgtcacaggaggtgcttactagatgcagccccccagaccttctctgtgctgattggaaaccgcgaatggctgaggcgcaacggcttaaccatttccaacgatgtcagtgacgctatgacagaccacgagatgaaaggacagacggccatcctggtggctattgatggtgtgctctgtgggatgattgctatagcagatgctgtcaagcaggaggccgccttggctgtgcacacgctgcagagcatgggtgtagatgtggttctgatcacgggggacaaccggaagacagccagagccattgccacccaggttggcatcaacaaagtctttgcagaggtgctgccttcccacaaggtggccaaggtccaggagcttcagaacaaagggaagaaagtcgccatggtgggagacggggtgaatgactctccggccttggcccaggcagacatgggtgtcgccatcggcactggcacagatgtggccattgaggcagccgacgtcgtcctcattagaaatgatttgctggatgtggtggctagcattcacctttccaagaggactgtccggaggatacgcatcaacctggtcctggcactgatttataacctggttgggatacccattgcggcaggtgtcttcatgcccatcggcattgtgctgcagccctggatgggctcggcagccatggcagcctcctccgtgtctgtggtgctctcatccctgcagctcaagtgctataagaagcctgaactggagaggtacgaggcacaggtgcacggccgcataaagcccctgacggcatcccaggtcagtgtgcacatcggcatggatgacaggcggagggactcccccagggccacgccatgggaccaggtcagctatgtcagccaggtgtcgctgtcctccctgacgtctgacaagccatcccggcacagcgctacagtggatgatggtggggacaagtggtctctgctcctgaatgacagggatgaggagcagtacatctgatggctccaggcgggcagggacttgcctccactcgccacaagccaagcaggacagccagctgcaggatgagcagagctagcttccagctttggggacttccactccctggacatgtccggtcaccccgccctgcgatgtgtggccttgtctgggtggagctggccttggcctggagaggatgttcctgcctgcttcctggcctcactgggccatcagcatgggctttgtcttggactctagtccttgcctgtaggactgtagaagatgagaagtgagtcaccctcctcacagaccttttctggagtatttaggatgactgctgtgaaatggagaacagtttcatcaggaccaaaaaacctcgctgggactttccagagaaccagacctcactgtcaggctctttctgatgacgcctgcgtgcctcatgtttctgagaccacagtttacctcaagtgtgtctgttgctttctgcctgcacagtctgttctttttctgacctgtgtgctttcactggggaccccgtgtgaccctgcctatcacctaggagggtgtccttgtggtccctgctgctgctctcaggtgcttctccatgctctggagtgtgcatttcaaactgaatctgcttcctggcatgcacatccccagccagggagcttggcacatcctccttcaaatcgaggagagttctttcttgcttaagggccccttctctgtagagtgggggcttctcaatagagtgttgttgctgaccagctggagtgagggtcttagagcctgacctgaatgtccagcctcggcttcctgtggagcctaggtgctcacaattcagggcatccttctgtgtccctgcccagcctgtggtgctcgaaacaggtgccccatgggagatgtatgtgtgcaggagcctccctgcatggccccaggagctttgttttcacgggcttctgtgcgactgtcaccttgtggggtccagtagagcattcatgtcactagtgtctggcgttgtgtggcttggaggaaacagtgctgcccaaataggaggaaagcacagcctccctgagcctgccttctgcacgctgcccaggggcctcaggaaaggagtggccacagctctactgtttacctgacaatggctctcagagcagcagaagaggtccagttattgactctgaagttggtggcgattgacagaaccccttggagttggattaaattctgggtgaaactcttgtctcccacacaaaatagtcatagttatctttttgagtgtccattacttgccagaggaagtgttagcagcacttttgatagattacctctaattttccagcaaaccagcaaggtacctatgactgtccacattttacaggcaaggaaacaggctctgagaagctgaggacctcgcccaggatgacatagccagtggacgagccgtgtctgtcggctctgaaggctttagtctcattgtccttttgccttgaatagaaatttgcctcataagaataaaaaggaaaaaggtctttgcctcctggaagaacgaatctaccaggtgatctagtaattatttcaactcagaatgcagttgattcaggaggtcctctgaccttcaccttggatggttagtttcaccttttacatgtagtttttgtggggttttattttatgaaatcaaagcgcaccgttcattgtgttttcattgttttcagccccccctccagccccagcggattcctgctctcccccggtaattgcatcctctctttatgcttgcttggggaatgtcgtttcctgaccaggctgatcattatctaaagaatctaattctgttgatttttaaaactattagaaccataacattgtgttcatctatggacctggaaatatttatataatttttatagaaaataaccttttagatggtcaaagtataaggaatttttttgtcagataaccatttctacttcaaaaacattccatgcaatattagaataaagttcctgtcattcctctaaaaa

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