LOCUS       XM_073662634            6559 bp    mRNA    linear   VRT 01-MAY-2025
DEFINITION  PREDICTED: Phyllobates terribilis ATPase copper transporting beta
            (ATP7B), transcript variant X7, mRNA.
ACCESSION   XM_073662634
VERSION     XM_073662634.1
DBLINK      BioProject: PRJNA1254268
KEYWORDS    RefSeq.
SOURCE      Phyllobates terribilis
  ORGANISM  Phyllobates terribilis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Dendrobatidae;
            Dendrobatinae; Phyllobates.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_027362762) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_046119375.1-RS_2025_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/25/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6559
                     /organism="Phyllobates terribilis"
                     /mol_type="mRNA"
                     /strain="yellow"
                     /db_xref="taxon:111132"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="liver"
                     /dev_stage="adult"
                     /geo_loc_name="USA"
                     /collection_date="2023-04-17"
                     /collected_by="Neil M Khosla"
     gene            1..6559
                     /gene="ATP7B"
                     /note="ATPase copper transporting beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 25 Proteins"
                     /db_xref="GeneID:141197116"
     CDS             193..4602
                     /gene="ATP7B"
                     /codon_start=1
                     /product="copper-transporting ATPase 2 isoform X3"
                     /protein_id="XP_073518735.1"
                     /db_xref="GeneID:141197116"
                     /translation="

MMSQKTFLKEEDEEEEVRLLDTTEDENAHQSSISHHYTSKNYGILKTNHTPPPRKPRFAFDNRGYDGSHNDLTDPCLEVSSVVVGIIGMTCQSCAQSIEGRISKIPSVVNIKVYLDKANAEVCYIPSEITPQKICEEIEDMGFDTNLDKCKELKGGLYKEEVVKMRVEGMTCQSCVNTIEGKIGKIQGVEKIKVSLANQEAMIVYCPQYIQPEDLRKQIDFMGFMASVKSKPDPTKLGPINIEHLQSISTDPKLKNTGRPIDNIIARTIHIEGMHCKSCVHNIEGSISGIPGVQNIKVSLENKNAVISLAEDVTSLLMLKKAIEALPPGHFKVTLPEDNERSPALQSKSNLCSSPNQSQRTSTRTASIRIGGMTCGSCVSTIENMISQRKGVQSISVSLPEGMGTILYIHTETTSEELRAAIEDMGFDATLISDSLLATSSDQLSSTLKPKLLETTKNANLHQDYIVDVPPKKPHPDIPLMENSSPQKCVLQVTGMTCASCVSTIERNLKKKDGIISVLVALMAGKAEVKYIANQIEPSEIAQLIENLGFGAVVLEDCTASHGSIELVITGMTCASCVHNIESRLMRTPGILQASVALATCKAQVKFDPEIVGPRDIIQIIEGIGFQASLSRREPSVHNLDHKEEIRQWRKSFLFSLIFGIPVICIMVYMLIANNNHHGQSVLDNNILPGLSIMNLIFFILCTLVQTFGGWYFYVQAYKSLKHKATNMDVLIVLATTIAYIYSVVILIVAIVEKSAQSPETFFDTPPMLFMFIALGRWLEHIAKSKTSEALAKLISLQATEATVLTLGPNHSVLREEQVAVELVQRGDIVKVVPGGKFPVDGKVIEGTSMADESLITGEPMPVRKKPGSMVIAGSINAHGSVLVEATHVGSDTTLAQIVKLVEEAQMSKAPIQQLADKISGYFVPFIISISIVTLIGWTTVGFVNFDVILKYFPDYSKTISKAEIIIRVGFQTAITVLSIACPCALGLATPTAVMVGTGVAAQNGILIKGGEPLEMAHKINTVMFDKTGTITHGVPKVMRVLLLGDVVRMPLKRMLAVVGTAEASSEHPLGMAMTNYCKEELGTQSLGYCTDFQAVPGCGISCKVNNVESVLVLSEEGINEQNVYISGLTHPQEDGSSIIAPELQGASAPQPHSVLIGNREWMRRNGLHISSDVDETMTSHEMKGQTAVLIAIDGTLCGMIAIADTVKQEAALAVHTLKAMGVDVVLITGDNRKTAKAIATQVGIKKVFAEVLPSHKVAKVEALQNEGKKVAMVGDGVNDSPALARADIGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINFMFALIYNLVGIPIAAGVFLPVGLVLQPWMGSAAMAASSVSVVLSSLQLKCYRKPDSDRYEARAQGLMKPLTPSQISVHVGMDDRRRDIPMTSTWDQISYISQVSSSRNSRQDSPTGDRQDKWSLLINEAEDDQYM"

ORIGIN      

tgagcgcagcctgcccggctgccggggaaaccaatgcctcactcataaaggctgacatgtgctcagcactgatggcagaggcggcggcggcggcggggtgcgggagtccagaggtcaccggctctgcacacactagtcaatggcagcagcgctgacgttgtgctggagcagagcggggactcgctagcaaagatgatgtctcaaaagacctttctgaaagaggaggatgaggaggaagaagtgcgattacttgacactacggaagatgaaaatgcccatcaatccagtatatctcaccattataccagcaagaactatggcatactcaagacaaaccatacaccaccaccaagaaaaccaagatttgctttcgacaacagaggctatgatggtagccacaatgacctcaccgacccatgccttgaagttagttcggttgtggtaggaattataggtatgacctgccagtcatgcgcccagtccattgaaggaagaatctcaaagataccaagtgtggttaacataaaggtttaccttgataaagccaatgcagaagtatgttacataccttccgaaataacaccacagaagatttgtgaggaaattgaagatatgggttttgataccaacctagataaatgcaaagaactgaaaggtggtctttataaagaggaagtagtaaaaatgagggtagagggtatgacgtgccagtcatgtgtcaataccattgaagggaaaattggaaaaattcaaggagtagaaaaaataaaggtttctcttgcaaaccaagaagcaatgattgtttattgtcctcagtatatccagccagaagacttacgaaagcagattgattttatggggtttatggcttctgtcaaaagcaaaccagatccaacaaaactcggaccaattaatattgaacatctacaaagtatctctacagaccccaagcttaagaatactggcagacctatagacaatataatagcaagaactattcatatagaagggatgcattgtaaatcatgtgtacacaacatagagggctccatctctggtatacctggtgttcagaacattaaagtctctctggagaacaaaaatgctgtaatatctcttgctgaggatgttactagcctactgatgttaaaaaaagcaattgaagctcttccaccaggacattttaaggttacccttccagaagataatgaacgcagtcctgcattacaatcaaaatcaaacctttgttcatctcctaatcaaagccaaagaacctccacaaggacggcgtcaatcaggatcggaggaatgacttgtgggtcttgtgtgtcaacgattgaaaatatgatctctcaaagaaagggagtccaatccatatcagtgtcattacctgaggggatgggaacaattctctatattcatacggaaactacctctgaggaattaagagcggctatagaagacatgggctttgacgctactcttatttctgattcactattggctactagcagtgaccagttaagctctacattgaagccaaagttactagagacaaccaagaatgcaaatctccatcaagattacattgtggatgttccccctaaaaagcctcacccagatatccctctgatggaaaatagttcaccgcagaaatgtgtcttacaagtcacagggatgacatgtgcctcatgtgtctccaccatcgagaggaacctgaagaagaaagatggtattatttccgtgctggttgcattgatggctggtaaagctgaggtcaaatacattgcaaaccagattgaaccatctgaaattgcacaacttattgaaaatctgggctttggagctgttgttttggaagattgcactgcatcccatggcagtatcgaactggtgattacaggtatgacatgtgcctcatgtgtccacaatattgaatcacgactgatgagaacgccaggtattctgcaagcctctgtggctcttgccacctgcaaagctcaagtcaagtttgatcctgaaattgttggtccccgagacatcatacaaatcattgaggggattggatttcaagcctctttatctagaagagagccatcagttcacaacctggaccataaagaagaaataagacagtggagaaagtccttcttgttcagcctcatatttggcatccccgtcatctgcatcatggtgtacatgttaatcgccaacaataatcaccacggacagtctgtgctggacaacaacatcctccctggtttatccataatgaacctcattttctttatactttgcacattagtccagacctttggtggatggtacttctatgtccaggcttacaagtctctgaaacacaaggcaaccaatatggatgtactcattgtcctggctaccaccattgcctatatttactctgtagttatcctgattgtggccattgtggagaagtcagcccagagcccagagaccttcttcgataccccccccatgttgttcatgttcatcgctctggggagatggcttgaacatatagcaaagagtaaaacttcagaagctcttgccaagctaatatccctgcaagctacagaggcgacagttctgacactaggacctaatcactcagtactaagggaagaacaagtggccgtggagcttgttcagaggggagatattgtgaaggttgttcccgggggcaaatttcctgtggatgggaaagttattgaagggacctctatggcggatgagtccttaatcacaggcgaacctatgcctgtgaggaagaagccaggaagcatggtcatcgctgggtccattaatgcccatggatcagtccttgtagaagcgacacacgtgggctccgacaccaccctggcgcaaatagttaagctggtagaagaggctcagatgtccaaggcgccaatccaacaactggcagataagataagtggctacttcgtccccttcataattagtatttccattgtgacattgattggatggactaccgttggctttgtgaattttgatgtcattctgaaatatttcccagattacagtaaaaccatctcgaaggctgagataatcatacgggttggcttccagactgccatcactgtgctgtctattgcctgtccttgtgctttaggtctggctacccccacggcagtgatggtgggtactggagtagctgcacaaaatggcatccttatcaaaggtggagagccgctggagatggcacataagataaatacagtgatgtttgataagactggaacaataacacatggggtccctaaagtgatgagagtgctgctgctgggtgatgtagtcaggatgccgctgaaacgaatgcttgccgtggtcggtactgcagaagccagcagtgagcatcccctgggaatggccatgacgaactactgcaaggaggagcttgggacacagtcactgggatattgtacagattttcaggcagtcccgggatgcggaatcagctgtaaagtgaataatgtagaaagtgtcctggtgctgagtgaggagggcataaatgagcagaatgtctacataagtggcctcacccatccacaggaggacggatcctcaatcattgctcccgagctacaaggtgcctcagctcctcaaccgcattctgtgttaattggaaaccgggaatggatgagacgcaatggactgcacatttccagtgatgtagatgaaaccatgactagtcatgaaatgaaaggacagactgcagtgctaatagctatagatggtacattatgtggaatgatcgctattgccgatacagtaaagcaggaggcagcgcttgctgtgcatacactaaaagcaatgggagtggatgtagtactgatcacaggagacaaccggaagactgccaaggcaatcgccactcaggttgggatcaagaaggtgtttgcagaagttcttccttctcacaaggtggccaaagtcgaagcattacaaaacgaagggaagaaagtagccatggtgggcgacggcgtcaatgactcccctgcattggccagagctgatattggcattgccattggcacaggaacagatgttgccattgaagctgcagatgttgtccttatcagaaatgatttgcttgatgttgtcgccagcattcacctctcaaagaggacggtgagaagaataagaattaacttcatgtttgcgctcatctataatcttgtcggcattcccattgcagcaggtgtattcctgccggtgggattggtgttacagccatggatgggatcagcagctatggcagcctcctctgtctcagtggttttgtcctctctacaactgaagtgctacaggaaaccagactctgatagatatgaagctcgagcccaggggctcatgaagccacttaccccatcacagataagtgttcatgtcgggatggatgaccggagaagagatatcccaatgaccagcacctgggatcagatcagctacatcagccaagtgtcatccagcagaaactcccgacaagattcaccaacaggcgacagacaagacaagtggtctcttctcatcaatgaggctgaggatgatcagtacatgtagcatcttgggtatacaccaggagatgaagaaccattgtctgtaataatgagacaatcattacggtctgcagtcatcacattcagcaatgatctgtagtgttaatggaataatgagcaaaattgctacactgaaacactataggaagagcagaatggatataagtgtatgggtgataacattctgatgttcttagcttgtattttcaagttctttaatgcttaaaattgcaaagtgcttgcaaaaaaaaggtactttgttcttgacagaatataagaagttaattatagagagatttttatttctatagtttactgctcgctggccatgttaccacttctgtagtctatcagcggtggttggtctccttcctaaaagagcttgtaagcactgctcagaagaggacagcatctcgctgcttccaatctgctttagtgtccatgtgtatctgcgacagtgcagagacaaaactgcatgtttgcagcacggcgcagtgcacatgttgtgccagtggtggcgctatgctgcagcttaggacaatcaatttagcaggagcgcatcgcctcccaacaagcaggaagctgcgaggctggggagcgatgccctcctggaaggttgtaatgagacaaaaccttttaggaattacacaataaggagattgagcctcggtgtaatggatactttattaggaggcaatgaaaatctccactaataattagaagccagataacgccattaccgaaatcatgtctgatatgaagataagtcggattcacccatccgtgtttcgtggtccaagtatgtaccgtgatgcacaggctggcaaccgggctgctcacccaaactatgcacccccatatatgcctatgaggcttttggaagtcaggtcaggagaccagcggctggtcggatgtgtgaatctgaggctatgtgcccacgatgcagagatgaagcagaaaatttccgcttcatttctgcatgtccttgcccggaaaaacgtgtgcggaatttgacacgcgtttttcacatgcggaattgccttgcgtttttctaatgcattgagaaggcaattctgcatgcgtaaacgcacaaataatgaacatgctgcggatttttccgcacatcaaaaacgctgcggaaaaatccgcagcatgggcattgaaagtgcgcattgtcattggggaccatggggggtggattaccaagcgtttcccaagcgtttacgctgcgcaaaaacgcttgaaaaacgcatcgtgggcacggaccctgaccctagagacaaatgatatgctggaagcgtttgaggtgccgcacagtatactgtcattatatataggggttgtccaggattacaaaaacatggctgctttcttccaaaaactatgagttgtgtagtacggcacctcaactccactgaagtgactggatctgagctgcaatatcatacaccacctttagacaagggtggccctggttttctaattctggttatccccctttatgaagaataacagattgggtcagttgagtgagtgcagtttactgttttttgtatctcaccttaaaccttgggattatagttatatcagtcggcccaaatgataagaaatttatggtaaaacctatcaacatgccataattgtctatgaagggaaaactcataggtcagcgcctcgtaacacgctccggctactgtactggcgaaggaattatagtaaacacatagtaatataattcattaacttgtgtagcaaaaggttaaaccaccaagcacttgaagggttaaactacaaagtcacatttatatagcgatctacaaaaaaaagctacgaaaatgtatagagtatagtgttgagagagtatgttctattaaccctttcgccgggtatgctcgggccgagctccgattatttatagctgctcggtgataaggttaaattgtgcctgtgtgcatgatttg

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