LOCUS       XM_071365406            6037 bp    mRNA    linear   VRT 18-FEB-2025
DEFINITION  PREDICTED: Salvelinus alpinus dicer 1, ribonuclease type III
            (dicer1), transcript variant X5, mRNA.
ACCESSION   XM_071365406
VERSION     XM_071365406.1
DBLINK      BioProject: PRJNA1211668
KEYWORDS    RefSeq.
SOURCE      Salvelinus alpinus (Arctic char)
  ORGANISM  Salvelinus alpinus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Salvelinus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_092110) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_045679555.1-RS_2025_01
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 01/27/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6037
                     /organism="Salvelinus alpinus"
                     /mol_type="mRNA"
                     /db_xref="taxon:8036"
                     /chromosome="25"
     gene            1..6037
                     /gene="dicer1"
                     /note="dicer 1, ribonuclease type III; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 Proteins"
                     /db_xref="GeneID:139553264"
     CDS             364..5892
                     /gene="dicer1"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform X4"
                     /protein_id="XP_071221507.1"
                     /db_xref="GeneID:139553264"
                     /translation="

MSGLQLVTPASNPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVILTKELSHQIRGDFAEHGKRTVFLVNTASSVIQQAAIVRTHSDLQVGEYTSAEKISAWSGEKWSQEMIENQVLVMTCHIFLHVLKNGVLPLSKLNLVVFDECHLAITDHPYREIMKLCEGSLCSPRILGLTASILNGKCDPSELEQKIQNLERILRSNAETATDLVVLDRYASQPREVVLDCGPYLDKSGLSECLLSELDEALHFLNDCNLSVPREDRDPTFITKQVLRDCRAVLLVLGPWCADKVAGIMVRELQKYIKHEQEEINRKFLLFTDTILRKVHALCEEHFSPASLDLKFVTPKVIRLLEILHEYKPFERQQFESVEWYNNRNEDNYVSWSDSEDEDEDEEVKEKPEAIFPSPFTNILCGIIFVDRRYTAVVLNRLIKEAGKQDTDLAYISSNFITGHSIGRNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYVMLADSERAKTFEDDLKTYKAIEKILRNKCSKAAGVGEFEVEQELDDDNILPPYVLRSEDAGARVTVNTAIGHINRYCARLPSDPFTHLAPKCKTKELQDGRYQSTLYLPINSPLRVPVAGPTMNCARLAEKAVALLCCEKLHKKGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKANSLNSSGMDSTRCQMRSTGMLAHVDSSASHSCVKLAGCPLGGGPFCITTGRDWEPHRAVHNWPSVVRVWQIPECLRDSYPVPQQSYYLYVVGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPRIPHFPVYTRSGEVTISIELQKAGFTLSAIQLDLITRLHQYIFSHILRLEKPALEFKPTQADSAYCVLPLNVVEDSITLDLDFKFMEDIEKSEARTGIPTTLYTKQNPFTFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLSNVNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSTEKRKAKWESLQNKQILVPELCVIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASNAGVGAQTLPPDFRYPNLDFGWKKSIDSKSFICPHDEEEYDDDDDEEEDSGDENCKHHDQTAAPDPAVAQQPCSDCHVSSQPERGDVSKHPEADRPEEEEPQQPDSASCTNTLTNGTAAVAKDNSENGDHTHLHDGRDSCQFLPAGPGSPLESEEVSTTMTTQSTTSVLPVQLSPSTENQNLTPTQPWTQSQLQHPQPRTQPQPRTQPQPWTQPRPPQPRDECKPGGTTGLREGDGHYVNQATSDSCSPATVTWPKGTAPITTTALLPDYSKTQETSSTGGDTPGPCPKILGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNVDESSEDKWDENETKEDPLDNGSAGKEFCEDEVELEEELLEEDEDLRWKESKEEVNIEDDLEYYQEHIKFIDNMLMGSGAFGKKISLRTFPAALATPVPGSSPSVRSSSPAAEPSFGVWKPPKKPGPVPTPDYPSEPGGGGSVDEFDYSSWDAMCYLDPSKAGEEDDFVVGFWNPSEENCGVELAKQSISYDLHTEQCIADKSIADCIEALLGCYLTSCGERAAQMFLCSLGLKVLPVESRTLREEGGVTEVANLDLQYGWLKIPPRCMFDHPDAERTLNHLISGFENFERKISYTFQNKAYLLQAFTHASYHYNTITG"

     misc_feature    457..1050
                     /gene="dicer1"
                     /note="DEXH-box helicase domain of endoribonuclease Dicer;
                     Region: DEXHc_dicer; cd18034"
                     /db_xref="CDD:350792"
     misc_feature    order(457..468,475..477,526..549,670..672,859..861,
                     952..954)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350792"
     misc_feature    order(634..639,706..711,784..786,790..795,802..804,
                     877..885)
                     /gene="dicer1"
                     /note="nucleic acid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:350792"
     misc_feature    1144..1428
                     /gene="dicer1"
                     /note="Partner-binding domain of the endoribonuclease
                     Dicer; Region: Dicer_PBD; cd15903"
                     /db_xref="CDD:277191"
     misc_feature    order(1159..1164,1171..1173,1177..1182,1357..1362,
                     1369..1374,1381..1383,1390..1395,1402..1404)
                     /gene="dicer1"
                     /note="Trbp binding interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:277191"
     misc_feature    1447..2019
                     /gene="dicer1"
                     /note="C-terminal helicase domain of the endoribonuclease
                     Dicer; Region: SF2_C_dicer; cd18802"
                     /db_xref="CDD:350189"
     misc_feature    order(1672..1680,1888..1890,1945..1947,1951..1953)
                     /gene="dicer1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350189"
     misc_feature    order(1900..1902,1906..1908,1981..1983,1987..1989)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350189"
     misc_feature    2215..2481
                     /gene="dicer1"
                     /note="Dicer dimerization domain; Region: Dicer_dimer;
                     pfam03368"
                     /db_xref="CDD:460900"
     misc_feature    3193..3561
                     /gene="dicer1"
                     /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse
                     involved in cleaving dsRNA in the RNA interference
                     pathway. It generates dsRNAs which are approximately 20 bp
                     long (siRNAs), which in turn target hydrolysis of
                     homologous RNAs. PAZ domains are named...; Region:
                     PAZ_dicer_like; cd02843"
                     /db_xref="CDD:239209"
     misc_feature    order(3382..3384,3421..3423,3439..3441,3451..3453,
                     3505..3507,3529..3531,3535..3537)
                     /gene="dicer1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239209"
     misc_feature    4654..>4929
                     /gene="dicer1"
                     /note="Ribonuclease III family; Region: RIBOc; smart00535"
                     /db_xref="CDD:197778"
     misc_feature    order(4705..4710,4717..4722,4729..4731,4738..4743,
                     4750..4755,4759..4767,4795..4797)
                     /gene="dicer1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238333"
     misc_feature    5788..>5868
                     /gene="dicer1"
                     /note="dsRNA-specific ribonuclease [Transcription];
                     Region: Rnc; COG0571"
                     /db_xref="CDD:440336"
ORIGIN      

cccaggtggaaggaggtatcgtggtggggaagttcctgacagcagcaagagggattggaggagagtgtatcagacgaaatatcaggacaattttcattcaagacggcccaataaaaaatatttattaggaaggaagaatcttcagctcctgaagcactgtcattaaagcctttcaactgtgtagagctcctctagttaagatgtgggggagtgtgatgagctgattgatgagcgttgatcatgaagcccagagtaagtgctgcctggtccatcacagagtatgaccctaccttaagttttagaggaagagaatgaggaaatgagatagactgcacccccagtatcccccagtcctgaagcaacatgtcaggactccagctagtcacccccgcctccaatcccatggggcctttctttggcctcccgtggcaacaggaggccatccacgacaacatctacacgcctaggaaatatcaggttgaacttcttgaagcagctcttgaacacaatactatcgtctgtttaaatactggctcagggaagacctttattgcagtaatcttaactaaagagctttcccaccaaatccggggagactttgccgaacatgggaagaggacagttttcctggtgaatacagcatcgtctgtgattcagcaagcagctattgttaggacccactctgatctccaggttggagaatacaccagcgcggagaagatctccgcatggtccggggaaaagtggagccaagaaatgatcgaaaatcaggtgctcgttatgacttgccatatcttcctgcatgtgctgaagaatggagtgttgccactatcgaaactcaacctggtggtgtttgatgagtgtcacctggcaatcacagaccatccctaccgggagataatgaagctatgtgagggctccctgtgcagccctcgcatcctgggcctcacagcatccattctgaatggtaaatgtgacccatctgaactggagcagaagatccagaacctggagcggatcttaaggagtaatgcagagaccgctactgaccttgtagtcctcgacagatatgcttcccagcccagagaagtggtgctggactgtggaccctacctggacaagagtggcctctctgagtgtctgctgagcgagctggatgaggctctccacttcctcaacgactgcaacctatctgtgcctcgagaggacagagaccccaccttcataaccaaacaggtgctgagggactgccgggcagtgcttttggtgctggggccatggtgtgctgacaaggtggctggtatcatggtgagggagctacagaagtacatcaaacacgaacaggaagagatcaacaggaagttcctgctcttcactgacaccatcctgaggaaggtccacgctctgtgcgaagagcacttctcccccgcttctttggacctaaagttcgtgacccctaaggtcatccgtctcttagagatcctccatgagtacaagcccttcgagaggcagcagtttgagagtgtggagtggtacaacaaccgcaacgaggacaactacgtatcgtggagtgactcagaggacgaagacgaggatgaggaggtgaaggagaagcctgaggctatcttcccctcgccattcaccaacattctgtgtgggatcatcttcgtggataggcgctacactgccgtcgtcctcaaccggctgataaaagaggccgggaagcaggacacagatctggcctacatcagcagtaacttcatcaccggtcacagcatcggcaggaaccagccacgcaacaaacagatggaggtggaattcaggaagcaggaagaggttctgcgtaagttccgagcccacgagaccaacctgctcatagcgaccagcatcgtggaggaaggagtggatattcccaaatgtaacctggtggtgcggttcgacctgcccactgagtacaggtcctacgttcagtctaaaggccgagccagagctcctgtatccaactacgtcatgctggctgacagtgagagggccaagaccttcgaggatgacctaaagacctacaaggccatagagaagattctgaggaataagtgttccaaggcagcaggggtcggtgagtttgaggtggaacaggagctggatgatgacaacatcctgcctccctacgtgctccgctctgaggacgcaggggcccgcgtcaccgtcaacaccgccatcggacacatcaacagatactgtgcccgtctgcccagtgacccgtttacccacctggcacccaagtgtaagaccaaggagcttcaggatgggcgctaccagtcaaccctctacctgcccatcaactcccctctacgggtgcccgtcgctgggccgacaatgaactgtgcaagactggcagagaaagcagtagcactgctttgttgtgaaaagcttcacaaaaaaggtgagttagatgaccacttgatgcctgtggggaaggagacagtgaagtatgaggaggagctggatctccatgatgaggaggagaccagtgttccaggcaggccaggatccaccaagaggaggcagtgctaccctaaagctaacagcctcaattcatcgggcatggactctacaaggtgtcaaatgcgttccacagggatgctggcccatgttgactccagtgcttcccacagttgtgtcaagttggctggatgtcctttgggtggtggaccattctgtatcacaaccggccgtgattgggagccccatagggcggtgcacaattggcccagcgtcgtccgggtttggcagataccggagtgtcttcgggacagttaccctgtaccgcagcagtcttactacctgtatgtggtcggcatggtcctcaccacccctctgcctgatgagctcaacttccgccgcaggaagctctaccctccagaagacactaccaggtgcttcggcatcctgaccgccaaacctatacctcggattccccattttcctgtttacacacggtctggtgaggtgaccatctccatcgagctccagaaggcagggttcaccctgagtgctatccagctggacctgatcactagattacaccagtacatcttctctcacatcctccgcctggagaaacctgctttggagttcaaacccacgcaggccgactcagcctactgcgttctacctctcaatgttgttgaggattcaatcactctagatttggactttaaattcatggaggacatagagaagtctgaggctcgtactggcattcctaccaccctgtacaccaagcagaaccccttcaccttcaaactggaagactaccaagacgctgtcatcattccacgctatcgtaactttgaccagcctcaccgtttctatgtggctgacgtttacacagacctcacaccacttagcaagttcccgtcgccagagtatgagacttttgctgagtactacaaaaccaagtacaacctggacctatccaatgtaaaccagccactattggatgtcgaccacacctcctcacgactgaacctcttaacccctcgccacctaaaccagaaggggaaagcactgcctctcagcagtacagagaagaggaaggccaagtgggagagtctacagaacaaacagatcctggtcccagagctatgtgtcatccaccccatcccagcctctctgtggaggaaggctgtgtgtctccccagcatactgtaccgcctccactgcctcctcacagctgaggagctgagggcccagacagccagcaacgctggagttggagcccagaccctgccccctgacttcaggtatccaaacctggactttggatggaagaaatccatcgacagcaagtctttcatctgtccgcatgatgaggaagagtatgatgatgatgatgatgaggaagaggatagcggtgatgagaactgtaaacatcacgaccagactgcagcccctgaccctgctgttgctcagcaaccctgtagtgactgtcatgtctcctcccagcctgagaggggtgatgtcagcaaacacccagaagctgacaggccagaggaggaggagccccagcagccagactctgcctcctgcaccaataccctcactaacggcactgctgccgtcgccaaagacaacagtgagaacggcgaccacacacaccttcatgacggacgtgatagctgccagttcctccctgctggccctggttcgccactggagagcgaagaagtatcaacaacaatgacaacacaatccactacctcagttcttcctgtgcagctctctccaagcacagagaaccagaatctaaccccaacacagccctggacccagtctcagcttcagcaccctcagccccggacccagcctcagccccggacccaacctcagccctggacccagcctcgacccccacagcctagagatgaatgtaaaccaggggggaccacagggctccgtgagggcgatggacactacgtgaatcaagctacctcagactcctgcagcccagcaacagtgacgtggcccaaaggcaccgctcccatcacaaccacagcacttttacctgactactcaaagacccaggagaccagttccacagggggggacacacctggcccctgccccaagatcctggggcccaacccggggcttatccttcaggccctgaccctatccaacgccagcgatggcttcaacctggagcgtctggagatgctgggagactcgttcttgaagcacgccatcaccacctacctgttctgtacttaccccgacgcacacgagggacgactctcctacatgaggagcaagaaggtgagcaactgtaacttgtatcgtctggggaagaagaaaggtcttccaagcaggatggtagtgtccatatttgatccgccggtcaactggctgccccctggctacgtggtcaacgtggacgagagcagcgaagacaaatgggatgagaatgagaccaaagaggaccccctggacaacggtagtgctggaaaggagttctgtgaggatgaggtggagctcgaggaggagttgctggaggaggatgaagatctgaggtggaaggagtctaaagaagaagtcaacatcgaggacgacctggagtactaccaggagcacattaagttcatcgacaacatgctcatgggctccggtgccttcggcaagaagatctccctcaggaccttccccgctgccctcgccaccccggtccctggctccagcccctccgtccgctcctcctcccctgcagccgagcccagcttcggggtgtggaaaccccccaagaaacctggcccggtccccacccccgactacccctcggagcctggcggtggtggctcagtagatgagtttgactacagctcgtgggacgccatgtgttacttggaccccagcaaggcgggggaggaggatgatttcgtggtgggtttctggaacccgtctgaggagaactgtggggtggagctggcaaaacagtccatctcctacgacctgcacacggagcagtgcatcgctgacaagagcatcgctgactgtatagaggcactgctgggctgctacctcaccagctgtggggagagggctgctcagatgttcctctgctcactaggactcaaggtgttaccggtggagagtcggactctgagggaggagggcggagtcacagaggtagcgaaccttgacctccaatatggctggctgaagatcccgccccgctgcatgttcgaccacccggacgcagagcgcaccctcaaccacctcatctccggctttgagaactttgagaggaaaatcagctacaccttccagaacaaggcctacctgctgcaggcgttcacacacgcctcctaccattataataccattacaggttagaaatatcacaatattagattgttaccagcggctggagtttcttggcgatgcaattttagactacctcataacgaagcacctttatgaagaccctcgccaacactctcccggcgtgctcacagacctgcgctcggcactcgtcaac

//