LOCUS       XM_070341944           11059 bp    mRNA    linear   INV 12-DEC-2024
DEFINITION  PREDICTED: Littorina saxatilis copper-transporting ATPase 1-like
            (LOC138969207), transcript variant X3, mRNA.
ACCESSION   XM_070341944
VERSION     XM_070341944.1
DBLINK      BioProject: PRJNA1148619
KEYWORDS    RefSeq.
SOURCE      Littorina saxatilis
  ORGANISM  Littorina saxatilis
            Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
            Caenogastropoda; Littorinimorpha; Littorinoidea; Littorinidae;
            Littorina.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_090250) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_037325665.1-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/06/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11059
                     /organism="Littorina saxatilis"
                     /mol_type="mRNA"
                     /isolate="snail1"
                     /isolation_source="shore boulder field crab ecotype"
                     /db_xref="taxon:31220"
                     /tissue_type="muscle from the foot"
                     /dev_stage="adult"
                     /geo_loc_name="Sweden"
                     /collection_date="2017"
                     /linkage_group="LG6"
     gene            1..11059
                     /gene="LOC138969207"
                     /note="copper-transporting ATPase 1-like; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 11 Proteins"
                     /db_xref="GeneID:138969207"
     CDS             198..5165
                     /gene="LOC138969207"
                     /codon_start=1
                     /product="copper-transporting ATPase 1-like isoform X2"
                     /protein_id="XP_070198045.1"
                     /db_xref="GeneID:138969207"
                     /translation="

MLQACEEEMEREAVLRLGQLTSADDAVTIQNLLTDQKGVVDAKVQYETREARVRYRPTETNPPILLGVLEDRAFSATIMDIQQSGDAASQKVAIDVDGMTCQSCVRNIEGNISHLDGVKDIHVSLENKQALVVFDASQTSASAVAEGISNMGFDAKVALGGDSGEQTRVIRVEGMTCQSCVRTIEGTMGSKQGISSIRVSLPDNQAIVRFNPCLISARQICEQIDDMGFDASLSDDEFAEIATRNKTPGSSRQCVISIGGMTCNSCVKNIESNISDKPGVKAIKVSLADQNGVVTYDPQIVKAAEIAEMIDDMGFDAKVAQQEDESLSDDEFAQIAARKAGGNGRKSCVISIQGMTCNSCVKNIESNIGAQPGILNIKVSLTDSNGVVTYDSKVTDPAKIAEMIDDMGFDAAVAQHDFPMGDQLANLNRSSNATQTCTISIEGMTCQSCVKKIESNMGNSAGIFSIKVSLADKNCQVDFDPAVVTPAQIGRMISDMGYRAFSLGDAAGTETQTVVVSIKGMTCQSCVNTIEGKLSEHPAVKSIHVSLSDETGTIMYDPSSATPKMLAEAIDDMGFDCAVQDGLKQDRGDQGKTIAHSASAVQMSSTGAVHFNKKVDEAGEFEKCFLTIKGMTCASCVANIERNINKIEGVKSILVSLMAQRAEVKFDPAYILPSQIANAVSDIGFNAKVNEAEGLGQGTVELTITGMTCASCVHLIQSNLLKRHGLLTASVALATSSGKFTFDTEICGPRDIIDAIKDMGFEAYLMTDDDKKAARYDHRDDIKRWRTSFLLSLIFGLPAMIVMIYFMFFYKPSEEGGEDHSNTTTTRPHKKSHKPQFMIADGLSLENLLMFILATPVQFIGGRYFYVQAYKAIKHGATNMDVLVVLATTISYLYSLIVVLVAMGLHERVSPITFFETTPMLMVFISLGRWLEHIAKGKTSEALAKLLSLQPSEAVLVTVDKENTILSEKIISVELVQRGDILKVVPGGKIPIDGKVVSGQSNCDESLITGESMPVSKKEGSTVIGGSINQHGTLLTEATHVGADTTLSQIVKLVEEAQTSKAPIQNLADKIAGIFVPIVCTLSTITLLGWVIAGYVDIKLIEEDFVDNGEVSKSEMIFEKAFQYAITVLSIACPCALGLATPTAVMVGTGVGALNGILIKGGEPLETTHKVRCIVFDKTGTVTHGVPRVARVSMFVTDSVCSFVKMIAICGTAEASSEHPIASAIVKYAKETLEAAVLGKTTDFKAVPGCGLKCKASGIESLLTGLDMDGVRNRRNKQGSLVIRIDSKSSQPSDSLHQALQIDDLAGAVAPATYEVLIGNREWMNRNGLTVTEEMDEVMTEHENQGHTAVLCTVDGVIVSMLAVADTVKSEAHVAIHELKKLVPEIILLTGDNKKTARAIAKQIGIKKVFAEVLPSHKVKKIRQLQAEGHKVAMVGDGVNDSPALAQADVGIAIGTGTDVAVEAADIVLMNSNLLDVFAAIKLSRKTVERIYMNFFFACLYNLLGIPIAAGVFVPWGLSLKPWMASAAMAASSVSVVVSSLGLKLFKKPKMKDLVTQEYHESYAKEQGLQGGVKESNKKSYNVKQTAGENVDDDEIAVYCGADVDAASRSGSRQGSLLSRLSNKIKSATNTPDQLSLLNNDDDLNMNEDSLSARV"

     misc_feature    228..>470
                     /gene="LOC138969207"
                     /note="Cation-transporting P-type ATPase [Inorganic ion
                     transport and metabolism]; Region: ZntA; COG2217"
                     /db_xref="CDD:441819"
     misc_feature    477..665
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(492..500,507..509)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    702..893
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(720..728,735..737)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    960..1151
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(978..986,993..995)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1242..1433
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1260..1268,1275..1277)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1509..1697
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1527..1535,1542..1544)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1728..1925
                     /gene="LOC138969207"
                     /note="Copper chaperone CopZ [Inorganic ion transport and
                     metabolism]; Region: CopZ; COG2608"
                     /db_xref="CDD:442020"
     misc_feature    2073..2261
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(2088..2096,2103..2105)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2298..2489
                     /gene="LOC138969207"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(2316..2324,2331..2333)
                     /gene="LOC138969207"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2562..4766
                     /gene="LOC138969207"
                     /note="P-type heavy metal-transporting ATPase, similar to
                     human copper-transporting ATPases, ATP7A and ATP7B;
                     Region: P-type_ATPase_Cu-like; cd02094"
                     /db_xref="CDD:319783"
     misc_feature    order(3594..3596,3600..3602,4698..4700)
                     /gene="LOC138969207"
                     /note="putative Cu binding site [ion binding]; other site"
                     /db_xref="CDD:319783"
     misc_feature    order(3726..3734,3936..3938,4149..4157,4245..4247,
                     4365..4373,4431..4433,4440..4442,4449..4451,4506..4508,
                     4515..4517)
                     /gene="LOC138969207"
                     /note="putative ATP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:319783"
     polyA_site      11059
                     /gene="LOC138969207"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

cccaaccctttcgatattgagagctacgtacaacttttaggacatgcgaccgactatggacaattgctctgtcatcggattggcggagaatgttatcagtattctccctgtgagcatttgagatcagttgtctcgtctcgaactttgctgtgtgcagaagtgagctactaacagttcatcgataaaaacaaactgggatgttgcaggcatgcgaagaggagatggagagggaggcagtactgcgactaggtcagctgaccagcgctgacgatgcagtgaccatccaaaacttgttgaccgatcagaaaggcgttgtggacgccaaggtgcagtatgagacgagagaggcgcgtgtgaggtacaggcccacagagaccaaccccccgatcttgctgggtgtgctggaagaccgcgcgttctcagccaccatcatggacattcagcagtctggagacgccgcctcacagaaggtggccatcgacgttgacggcatgacctgccagtcgtgtgtgcgcaacattgagggcaacatctcacaccttgacggggtcaaggacatccacgtgtcgctggagaacaagcaggccctggtggtcttcgacgcgtcccagacgtcagccagcgccgtggcggaagggatcagtaacatgggattcgacgccaaggtggctttgggaggggactctggggaacaaacaagagtgattcgagtggagggcatgacctgccagtcctgcgtacgcaccatcgagggcaccatgggaagcaagcagggcatcagcagcattcgagtcagcttgcccgacaaccaggccatcgtacggttcaatccctgcctgatatctgcccggcagatttgtgaacagattgatgatatgggctttgatgcttctctcagtgacgatgaatttgcggaaattgcaactcggaataagacgccaggcagcagcaggcagtgtgtgatcagcattggaggaatgacgtgtaactcttgcgtgaagaacattgagtccaacatcagcgacaaaccaggggtcaaggccatcaaggtgtccttggctgaccagaacggtgtggtgacctacgaccctcagatcgtgaaggcggctgagatcgctgaaatgattgacgacatgggctttgacgctaaggtggctcagcaggaggatgagagcctgagtgacgatgagtttgcccagattgccgccaggaaggcaggagggaacggacgcaagtcttgtgtcatcagcattcagggcatgacgtgcaactcatgtgtgaagaacattgagtccaacatcggtgctcagccaggcatcctcaacatcaaagtgtccttgacagactctaatggcgtggtgacctatgacagcaaggtcacggatccagcgaagatcgctgaaatgattgatgacatggggtttgacgctgcagtggcccagcatgactttcccatgggtgaccagctggccaatctcaaccgttcgagcaacgccactcagacttgcaccatcagcatcgagggaatgacctgccagtcatgcgtgaaaaagattgaaagcaacatgggcaattcagcgggcatcttcagcatcaaagtgtctctcgctgacaagaactgtcaggtggattttgaccccgcagtggtgactcccgcccagatcgggcgaatgatttctgacatgggatacagagcgttttctcttggagacgcagcggggacagaaacacagacagtggtcgtatccatcaagggcatgacctgccagtcctgcgtcaacaccatcgagggcaaactgtcggaacacccggctgtcaagagtatccatgtgtcgctgtctgatgagacggggacaataatgtacgaccccagcagtgccacgcctaagatgctggctgaagccatcgatgacatgggattcgactgtgctgtgcaagatggcctcaaacaggacaggggagaccagggaaagacaattgctcattctgcgagtgcggttcaaatgagcagcactggcgctgtacacttcaacaaaaaagtggacgaggccggtgaattcgagaaatgcttcctcaccatcaagggcatgacctgtgcatcctgcgtcgccaacatcgagagaaacatcaataaaattgaaggcgtgaaaagtatcctggtgtccctgatggcacagagggcagaggtcaagtttgaccccgcctacatccttccctcacaaatcgccaacgcagtctccgacattggcttcaacgccaaggtcaacgaggcagagggactgggacaaggcactgtggaactaacaatcacaggcatgacgtgcgcatcatgtgttcacctgatccagagcaatttgttaaaacgccatggtcttctgacggcgtctgttgctttagccacctcttctggaaagttcacctttgacaccgagatctgcgggcccagagacatcattgacgccattaaggatatggggtttgaggcgtacctaatgacagatgatgacaagaaggccgctcgctacgatcacagggatgatatcaaacgatggagaacgtcgttcctgttgtcgctgatcttcgggctgccagccatgatagtgatgatctacttcatgtttttctacaaaccttcggaggagggaggggaggatcacagcaacaccaccaccacccgcccccacaagaagtcccacaagcctcagttcatgatcgctgatggcttgtccttggaaaatctcctcatgtttatcttggccacacctgtgcagttcatcggtggacgatacttctacgtccaagcgtacaaggcgataaaacacggagcgaccaacatggatgttctggttgtcctggcaaccaccatctcctacctgtattccttgattgtggttctggtggccatggggctgcacgagagagtttcacccatcactttctttgagaccacgcctatgttgatggtcttcatttcccttggcagatggctggaacatattgctaagggcaagaccagcgaagccctggccaagctgctatcactacagccatcagaagcggtgctggtgacggtggacaaggagaacaccatcctgtcggagaagatcatcagtgtggagctggtgcagcgcggtgacatcctcaaggtggtgccgggcggcaagatccccatcgacggcaaggtggtcagcggtcaatctaactgcgacgagtctctcatcacgggggagagcatgcctgtgtccaaaaaggaagggtccaccgtgattggtggcagtatcaaccagcacggcactctgctgacggaagcaacacacgttggggccgacaccacactctcacagattgtcaagctggtggaagaagcacagacatctaaggcccctattcagaatctggcagacaagatagctggtatctttgtgcctattgtgtgtacgctgtccactatcacgctgctgggctgggtcatcgctggatatgtggacattaaactcattgaagaagactttgtggacaacggagaagtgtcaaagagcgagatgatcttcgagaaggcgttccagtacgccatcacggtgctgagcatcgcctgtccctgtgccctcgggctggccacacccactgctgtcatggtggggacaggggtcggggcactcaacggcattctcatcaagggaggcgagccgctagaaaccacacacaaggtgcgttgcatcgtgtttgacaagactggcacagtaacacacggcgtgccccgagttgcgcgtgtgtccatgtttgtgacagactcggtgtgttctttcgtcaagatgatcgcaatctgtggcactgctgaggccagcagtgaacaccccatcgcttctgctatcgtcaagtatgccaaggagactctagaggcagcggtgctgggcaaaacgacagacttcaaggctgtgccagggtgcggcctcaagtgcaaggcgtccgggatcgaatccctgctgacggggctggacatggacggtgtgaggaaccgccgcaacaagcagggcagtttggtcatccgcatcgactccaagtccagtcagccgtccgacagtctgcaccaggccttgcagattgacgatctggcgggagcagtggcaccggcaacgtacgaagtgctgatcggaaaccgggagtggatgaatcgaaacggtctgacggtgacagaggaaatggatgaggtgatgacagagcatgagaatcagggtcatactgcagttctctgcactgttgatggtgtgattgtttccatgctggcggtagcagacacagtcaagtcggaggcccatgttgccatccatgagctgaagaagttggtgccagagattatcctcctgacgggcgacaacaagaaaacggcacgggccattgctaagcagattggaataaagaaggtgtttgcggaggtgttgccatcccacaaggtgaagaagattcgtcagctgcaggcagagggtcacaaggtggccatggttggagacggagtgaatgattcgccggccctagctcaggctgacgtcggcatcgctataggcactggcactgacgtggctgtggaggctgccgacattgttctcatgaatagcaacctcttggatgttttcgctgccattaaactgtcaagaaaaacagttgaacgcatctatatgaacttcttctttgcctgtctctacaacttacttggcatccccattgctgctggagtgtttgtaccttggggcctgtccctcaaaccctggatggcttccgctgctatggcagcctcctctgtctctgtcgtggtctcgtctctgggtctcaaattgttcaaaaagcccaagatgaaagatctggtaacacaggagtaccacgagtcctacgcgaaggaacagggtctccaaggaggggtcaaggagtccaacaagaagtcctacaacgtgaaacagacggcgggagagaatgttgatgacgatgaaatcgctgtctactgtggggccgatgtggacgcggcctccaggtcgggaagtcggcagggcagcttgttgtcgcgtctgagcaacaaaataaaatcggccaccaacacccctgaccagttgagtttgctgaataatgacgacgatctaaacatgaacgaggacagtttaagcgctcgggtctgactgactggacaaggaattgatacagacagggttaaggcagaagggtttgaagatcggagttaaaccactaagagagtatagctataaggcatatagttaaagcctggacagaacccaaaggtgcactgccgtatcccatgcagtttgaagattcttccaaatcataattttccaagcaaactgttcattatttagcttgtaagtaaaaatctcgggtgcttaccattttacggaatctgttcttttgttagttgctgtcaattttgaaacattgctttgcgtcaaatgtttttttgtaagcagccatcatgatcactagtacaatgcacatgctgattatttttgtgaactgattactgtgcaactgaatttctttttgttgataatctttttctaggtatgttttatttgttttatgatttgttttgtcgttgtagatattgttgcatttgtgcttgttgtagtgttgcatttgtctaagcaggaacacccagcttttggactagtttgcttcaaatatcatggtttagctttttgtttgtatattttaaataaaacttgtgccctgttgtgcactctgcattcgtgttgttgttgttgtgagtttaatcatgtttttgattctgatttcaggcgaaaactcgtcagtcatgttgaaccaatgtagctagaatcatgtggtaatacggttgtttgtaccttttgtgggaaatcccttgcatggtattggtagtcctgacaagcaaactctgaaactccagcttccactccctcttgatgccagaaggtcaacatgaagtatcttttgtcctgcttggtacagtgcagtttcactggcaacaaaagcaaacttcattatcagaaagcatgatggttgtactgtacagtggtacttgggacgtgaagtccgcatgtccaatgagaccccccgcgggttagggggagtcccatattggttgggacgagaaagaatttacccgatgctacccagcatgtcgtaagaggcgactaacggttctgtttctccttttacccttgttaagtgtttcttgtatagaatatagtcaatgtttgtaaagattttagtcaagcagtatgtaagaaatgttaagtcctttgtactggaaacttgcattctcccagtaaggtcatatattgtactacgttgcaagcccctggagcaattttttgattagtgcttttgtgaacaagaaacaattaacaagtggctctatcccatctcccccctttcccctatcccatctcccacctttccccgtcgcgatataaccttgaatggttgaaaacgacgttaaacaccaattaaagaaagaaagaaagaaagatgtccaatcagagaacgtgtcaccccaattgaggacactttctcttgtccattagaccaaaacatacctgctgtgtgacctggccgcctgtataatggggacagttaaaatgggctggttgtaaggttgtcctttcatcacaggtaccactgcagtacaaattttgcactggtattatatactgacttgaaaacagatgtatgtagattaattctgccagcatgcaaaaaaagtaatgaaacgacagaggaagaaagttggcactttctattcccgaatgagaaaaagagtttgcttgtgatcgggcggtccgttttgattctgtttgtgtggatatttctttttatttgagtatcatttgttttcagctttggttgtattttttttcagtttcatgtctgagaattgcttctttgagtaatggcaaatttcatggcaaatttcacatcaagacaggaacatgtcaacagatctgaaattcttatgagaaatgagccagcgacacaaagaggacgactgcactgttggtttatcaaccgttgggatcctgtgcacatagggttgcatgcttctgttctggttctgtttctgcttcagttgtttcagttttggtgttgctgttctggttctgtttctgcttcagttgtttcagttttggtgttgctgttcatgcgatttactttaccagtaatatttatctacttctgttgacgtcacaaggtgactcgctgcttgcactctttacacccccggtataggggtgtgtataggtttcgctcgatgtgtttgtttgtttgtttgtttgtttgtgttcgcatatagatctcaagaatgaacggaccgatcgtcaccaaacttggtgaacaggttctatacattcctgagacggtccttacaaaaattgggaccagtcaaacacacggttagggagttattggtggattaagattatacaaggacttatagagggacatcttcatggtcaaagggaaataaccattctcactcagtcactgccaccaactgagaaggttatttccctttgacgggggtgtttttcctacctcggaggaatttcttgtttttgagtcacttgagaaaaagtgactctatgtaatcggtcagtgttagtctgtccgtccggccggccgtccggccggccgtccgtagacaccaccttaacgttggacttttctcggaaactatcaaagcgatcgggctcatattttgtttagtcgtgacctccaatgacctctacactttaacgatggtttcgttgacctttgacctttttcaaggtcacaggtcagcgtcaaaggaaaaattagacattttatatctttgacaaagttcatcggatgtgattgaaactttgtaggattattctttacatcaaagtatttacatctgtagccttttacgaacgttatcagaaaaacaagggagataactagccttttctgttcggcaacacacaacttaacgttgggcttttctcggaaactataaaagtgaccgggctcaaattttatgtgaacgtgactcattgtgttgtgaatagcaatttcttcctgtccatctgatgcctcatataatattcagaactgcgaaagtgactcgatcgagcgtttgctcttcttgttttctgtcttcttgttttgttcttggttgtttttttccgttgtagagagggtattcatcctgttaggatttagacatgggtatatgggtgtgggattgtaggatttagacatgggtatatgggtgtgggattgtaggatttagacatgggtatatgggtgtgggattgtaggatttagacatgggtatatgggtgtgggattgttggcaaaacgtagagttttgatggaacatgcactttgagcaagatcagactcaagcggcactgcatgagcaacatctagctgctgcacttgttctgttccagacagtggggtgaagggacagttgctgtttattttcctgagaataaatcatagcgttattggataattctgtgtgttttgacagaaacatttggaaacctttttcccccatgtgtacattgtagcagaaatgtgtgattccatgcagagtaggttttcccaattccaatgattacttgtactggttgcaacagttgttgtcatttatattaccacatactgatactgtcttgttatagcttctcctgaagtatgtttttaaaatcagaagttgattcgattatttttgaaattatttttacaggtttattctatatgtctaagcaaagttattcacagaaagatttgcaatgcttagatgtaatatatacatgtataagtattgaacatttcttgactgttgttttcatttgtattttttctaaacatcccatatttattataggttacatgtgcctcttgttgtgaggggaaaagctgtaaaagctggactccatttactgtgtgtgtgtgtgtgtgtgtgtgctgtgtgctattcaatcgtctttgtgatatcatacatcagacaataaggaacagcaacacgcttatagtgtacgtctatcgtggaaatcctcaacagcattgttgacactaattcctccgaaaacggcgtatggctgcctaaatggcggggtaaaaaacggtcatacacgtaaaattccactcgtgcaaaaaacacgagtgtacgtgggagtttcagcccacgaacgcagaagaagaagaagttgacactaatgatttctccatgcttacctaaatttggctggaatctgtgcaagaaatgtggaattctatacaagaggcattctatgtacatctcagtactactcattaaatttaaagtttcaatgtgttttatacctgtgtacaatgatgctcattattttgacagtctcatcttggcatactacggaattagccctgtggaactgacaacatgaaatgaatgaagagcaaagaattgagattcactcaatgtgacggtgaacctcacacgggactgaatcaggatgttgccctcgtctttggttcttttgttcagtgagctcatatataaagtcacttttaatggccaaagttgtgacgaacactgtttgtatgatacacacactgtgtatatatgaaggactgggtggccgagtggtaacgcacttgcgctcggaagcgagaggttgcgagttcgaccctgggtcagggcgttagcaattttctcccccctttcctaacctaggtggtgggttcaagtgctagtctttcggatgagacgaaaaaccgaggtcccttcgtgtacactacattggggtgtgcacgttaaagatcccacgattgacaaaagggtctttcctggcaaaattgtataggcatagataaaaaaaaaatgtccaccaaaatacccgtgtgacttggaataataggccgtgaaaagtaggatatgcgccgaaatggctgcgatctgctggtcgatgtgaatgcgtggtgtactgtgtaaaaaattccatct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