LOCUS       XM_069915726            6202 bp    mRNA    linear   VRT 18-NOV-2024
DEFINITION  PREDICTED: Narcine bancroftii dicer 1, ribonuclease type III
            (dicer1), transcript variant X9, mRNA.
ACCESSION   XM_069915726
VERSION     XM_069915726.1
DBLINK      BioProject: PRJNA1181001
KEYWORDS    RefSeq.
SOURCE      Narcine bancroftii (Caribbean electric ray)
  ORGANISM  Narcine bancroftii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Batoidea; Torpediniformes; Narcinidae; Narcine.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_091470) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036971445.1-RS_2024_11
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 11/13/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6202
                     /organism="Narcine bancroftii"
                     /mol_type="mRNA"
                     /isolate="sNarBan1"
                     /db_xref="taxon:1343680"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="blood"
                     /dev_stage="adult"
                     /geo_loc_name="USA: Apalachee Bay near Panacea, Florida"
                     /lat_lon="30.037222 N 84.170833 W"
                     /collection_date="2020-10-03"
                     /collected_by="Gavin Naylor"
     gene            1..6202
                     /gene="dicer1"
                     /note="dicer 1, ribonuclease type III; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 6 Proteins"
                     /db_xref="GeneID:138753145"
     CDS             1834..6120
                     /gene="dicer1"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform X2"
                     /protein_id="XP_069771827.1"
                     /db_xref="GeneID:138753145"
                     /translation="

MAGLQLMTPASSPMGPFFGLPWQQEAIHDNIFTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLTKELSHQIRGQFNKNGSRTVFLVSSTRSVAQLAAAVKTHSDLKVGEYSIMEHIELWAKEEWNKHCSGRQVLVMTCHIFLHILRRGYIFLSNINLLVFDECHLAIKDHPYQEIMKMCEENPSCPRILGLTASILNGRCDPCELEEKILKLEKILRSSAETATDLVVLDKYSSQPHEVVLDCGPYEDRSGLYKKLLKELDEALNFLNDFSNVSVHCDDRGPTSVPKQVLVDCRAVLTVLGPWCADKVAGMMVRELQKYIKHEQEELNRKFLLFTDTLLRKIHALCEEHFSPATLDLKYVTPKVSKLLEILHQYKPFERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKTDTNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDLELSYVSSNFITGHGIGKNQPRNKQMEVEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLSDSDKIEDFKEDLKTYKAIEKILRNKCSKSVDTADVELEPVTDDDDLLPPYVLRPEDGSPRVTINTAIGHVNRYCARLPSDPFTHLAPKCKTQELSDGTFQSTLYLPINSPLRVPVTGLPMHCTRLAEKATALLCCERLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSIPGRPGSTKRRQCYPKAIPECLRNSYPKANQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELGKLDFTLSTKQLELITRLHQYIFSHILRLEKPALEFKPTEADAAYCVLPLDIVDSSSHLDIDFAFMEDIERSEARTGIPNTQYTKEKPFSFNLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTAKEAGVGIEALPSNFRYSNLDFGWKKSIDSKAYILAASSCTDENECYCKHSTTVAPEDAAHRGAIDQSSSENLHQMSVNKTTIKSLSPKKLFSADKVTKSTILVNGVICTENLTNGNAELLNQGCICHQNPINSCRHDLFVQPATSVPAHNTHHENQPKPRFECNRQSNNLDGIINKSTSDCCSKEAVSCKSSEPPAIPQWISHSGDYPPGAYTTETLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKYIADKSEMKDMIVTSDWNSLEMQFWTTSLPSTFTKIPDSILLEC"

     misc_feature    1927..2520
                     /gene="dicer1"
                     /note="DEXH-box helicase domain of endoribonuclease Dicer;
                     Region: DEXHc_dicer; cd18034"
                     /db_xref="CDD:350792"
     misc_feature    order(1927..1938,1945..1947,1996..2019,2140..2142,
                     2329..2331,2422..2424)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350792"
     misc_feature    order(2104..2109,2176..2181,2254..2256,2260..2265,
                     2272..2274,2347..2355)
                     /gene="dicer1"
                     /note="nucleic acid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:350792"
     misc_feature    2620..2901
                     /gene="dicer1"
                     /note="Partner-binding domain of the endoribonuclease
                     Dicer; Region: Dicer_PBD; cd15903"
                     /db_xref="CDD:277191"
     misc_feature    order(2629..2634,2641..2643,2647..2652,2830..2835,
                     2842..2847,2854..2856,2863..2868,2875..2877)
                     /gene="dicer1"
                     /note="Trbp binding interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:277191"
     misc_feature    3115..3495
                     /gene="dicer1"
                     /note="C-terminal helicase domain of the endoribonuclease
                     Dicer; Region: SF2_C_dicer; cd18802"
                     /db_xref="CDD:350189"
     misc_feature    order(3151..3159,3367..3369,3424..3426,3430..3432)
                     /gene="dicer1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350189"
     misc_feature    order(3379..3381,3385..3387,3460..3462,3466..3468)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350189"
     misc_feature    3694..3960
                     /gene="dicer1"
                     /note="Dicer dimerization domain; Region: Dicer_dimer;
                     pfam03368"
                     /db_xref="CDD:460900"
     misc_feature    4465..4830
                     /gene="dicer1"
                     /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse
                     involved in cleaving dsRNA in the RNA interference
                     pathway. It generates dsRNAs which are approximately 20 bp
                     long (siRNAs), which in turn target hydrolysis of
                     homologous RNAs. PAZ domains are named...; Region:
                     PAZ_dicer_like; cd02843"
                     /db_xref="CDD:239209"
     misc_feature    order(4651..4653,4690..4692,4708..4710,4720..4722,
                     4774..4776,4798..4800,4804..4806)
                     /gene="dicer1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239209"
     misc_feature    5698..>5973
                     /gene="dicer1"
                     /note="Ribonuclease III family; Region: RIBOc; smart00535"
                     /db_xref="CDD:197778"
     misc_feature    order(5749..5754,5761..5766,5773..5775,5782..5787,
                     5794..5799,5803..5811,5839..5841)
                     /gene="dicer1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238333"
ORIGIN      

gccgaaagagaagaaaaggagttagaggaatgaaggaaggggcggggaagagaagaaaatgaatggggaggatgtttctggagatcggagaagaaccaggatggatcacatcaaattggaagaaacacaaaaggggaagaatcaggattccggatctggagcttaaggagccttaaaccagcgttgtatttaagcagtacctgcagctttatgctttggaatattaagagggtagctagggagagaattgataccattaaatgcatttgactaaatgaccaccaaccggcaacactgacctccaccatcatgaagtgtttggagcaactggtaatggagcacatcaaagcgcacctacgagtgacagtggaccaattccaatttgcctactgtacactgaccctccactctgtcctgacccacctcgagaacgatgcctcgtacgccaggatgttggttgacttcagtacaataatacctccaaggctggtcgataaactgtcgtcgctgggactctattcctctgtgcatgacttgattgaaagaccaccgtctgtctgggttggcagcaaaacctccagcctcatgacactgagcactggcgcacctcagggctgcaggaatatagacagagtaaatgcaagtcggctttttccactgagggtgggtgagctacaaaccagggggcatgggttaagggtgaaagggaagaagtttaacaggaacatgagggtactggaagtctggatgagctgccagctgaagtggtgaatgtggggtcaattttaacattgaagaaaaattgggagaggtgtggagggctatggactgggtacaggtcagtggaacaagtttggcacagaatcatagggcgaaaggatctgttttctttgctgtagtgttctaggatttacagagaggaggcttgtacagtggtgcaagagcaacttgcacatgatggttatggacttcaggaggatgaaggaccactccccactacatatccatggctccatcacggagagactgggggaacacaaagctccttggcatccatttaaaaagactaccaatctttgaccaacaatagaaggtgtagcagcacattcacttcccaaggaagttgaggggggacaaggccaccatcctaagaatgtcgtacaagagtgtcctgtctggttgcattatcatttgattggaggcaagttcaaagggttattaaaactgctaagatgatcactggggtctcccttctctatatcaacgttaactacagggagcggtgcttaaagagggctcagagaatcatcgatgaccctgaccatccaggctgcagtatctttgagacattgccttcaaagaagaggtacgagagcataaaaaccaggactgccaggctgggaaacagcttcttcctgcaggcggtgagacttgaacaatcctagaaacacatcagttatttttgtatatacaggttcttgacaactttaatgtaaggggacgctgaagtagcagacgcctaaattgcaatgtcggcataatttttaccttggattcctaaactcctggggtgaagcacattcactacacgcacatatctgtggctagtcctgcaaaaagaagctcgaccttggacttaaaccagcaaagcatcaatgtccaaggaattaaaggttgaggaatgacgtgattacacaaagaaaacggctctcacgatgttaacattttataaaaacaggccaaatgtagacgtcagtgaaactgctttgctgcaacacatgaaatgacagaaacactggatgtgtgagaggacctgcattgtgaaatctaagaatggcaggattacagctcatgacacctgcttcatcaccaatgggcccattttttggactgccatggcaacaggaagctatccatgacaacatttttacaccaaggaaatatcaggttgaacttctagaagcagctttggaacataatactatcgtttgtttaaatactggctcagggaagacctttattgcagtgttactcacaaaggaactatctcatcagatcaggggacagttcaacaagaatggctcacgcactgtgtttttagttagttcaacaagatctgtggctcagctggcagcagctgtcaagacccattccgatctgaaggtgggagagtattccattatggagcatattgaattgtgggcaaaggaagaatggaataaacactgcagtggacggcaggtgctagttatgacgtgccacatcttcttgcacatattaaggagaggctacattttcctctcgaatattaacttgctggtgtttgatgaatgtcaccttgcaattaaagaccatccttatcaggaaattatgaagatgtgcgaggaaaatccttcctgccctcgtatcttgggactaactgcctccatcttaaacgggaggtgcgatccttgtgagctggaggagaaaattctgaagttggaaaagattctccggagcagtgcggagaccgccactgacctggtggttttggacaagtattcttctcagcctcatgaagttgtgctagattgtggcccatatgaggatagaagtggattatacaaaaagcttttaaaagaattagacgaagcacttaattttcttaatgacttcagtaatgtatctgtacactgtgatgatcgaggcccaacttcagtcccaaagcaggtactggtagattgccgtgcagttttaaccgttctcgggccttggtgtgccgataaagtagctgggatgatggtgagggaactccagaaatacataaagcacgagcaggaggagttgaacaggaagttccttttgtttacagatactcttctgaggaaaattcatgcactctgtgaagaacacttctcacctgctacactagatttgaaatacgtgactcctaaagtcagcaaactgttggaaatcttgcatcaatacaaaccctttgagcggcagcagtttgaaagtgttgaatggtacaacaacagaaaccaggacaattacgtgtcatggagtgattctgaagatgacgatgaggatgaagaaatagaggagaaagagaagactgacactaactttccatcccctttcactaatatactttgtgggattatttttgttgagagacgctatacagcagttgttttaaacagattaataaaggaagctggtaaacaggatctggagttgtcttatgtcagcagtaattttataactggtcacggcattggaaagaaccagcctcgtaataagcagatggaagtggaattcaggaaacaagaagaggtgctgagaaaattccgtgcgcatgaaaccaatttgctcatcgcaactagtgttgtcgaggagggagttgatattccaaaatgcaatctggtagttcgatttgacttaccaacagaatatcgttcttatgtgcaatctaaaggaagagcacgggctcccatctccaactacgtcatgctttcagattctgacaaaattgaagacttcaaagaggatctcaaaacctacaaagcaattgaaaagattcttcgaaacaaatgctcaaaatctgtggatactgctgacgtggaactagaacctgtaactgacgatgatgacctgcttcctccatatgtactgagaccagaagatggtagcccacgggtaactattaacactgccattggacatgtgaaccgatactgtgccagattaccaagtgaccccttcacacatttggctccaaagtgcaaaacccaagaactatcagatggtacttttcaatcaactctctatcttccaatcaactcgcctctccgcgtcccagtaactggtcttccaatgcactgtacaagattggctgagaaagcaacagctcttctttgctgcgagcgtctgcacaagataggcgaactggacgatcacttaatgccggttggaaaggaaaccgtgaaatatgaagaagagcttgatttgcatgacgaagaagaaactagcattcctgggagaccaggttccacaaaacggagacagtgctatccaaaagcaattcctgaatgtcttcggaacagttaccccaaagcaaatcaaccttgctacctgtatgtgattggcatggtgttgaccactcctcttcctgatgaactcaacttcagaagaagaaagctgtaccccccagaagatacaactcgatgttttgggattctgactgccaaaccaataccacagattccacattttccagtgtacacacgttctggtgaggttaccatatctattgaattgggtaaattggacttcacattgagtaccaagcagctggagctgatcactaggctacaccagtatatcttctctcacattcttcgactggagaaacctgcactagaattcaagcctacagaagctgatgcagcctattgtgttctacctcttgacatagttgatagttccagccatttggatattgatttcgcctttatggaagatatagaaaggtcagaagctcgcacaggcattcccaatacacagtacacaaaggagaaaccattctcgtttaatttggaagattatcaggatgcagttatcattccaagatatcgaaactttgaccagcctcatcgcttctatgtggccgatgtatacacagatctcacacctctcagtaaatttccttctcccgagtatgaaacatttgcagagtattataaaaccaagtacaatctggatctgaccaacttgaaccagcctttgctggacgtggaccacacatcttccagactgaatcttctaacacctcgacatttgaatcaaaaaggaaaagcacttcctttgagcagtgccgagaagcgcaaggccaaatgggagagtctacaaaacaagcagattcttgtcccagagctttgtgctattcatcccatcccagcgtccttgtggagaaaggctgtatgccttcccagtattctttatcgactgcactgtctgttaacagcagaagagctgagagcccaaacagcgaaggaagcaggtgttgggatcgaagctctcccttcaaacttcaggtattccaaccttgattttgggtggaaaaagtctatagacagcaaagcttatatcctggctgccagctcctgtacagatgagaatgagtgttactgtaagcacagcacaactgtagcccctgaagatgctgcacatcgaggagctatcgaccagagctcctccgagaaccttcaccagatgtctgtgaacaaaacaaccatcaagagtttgtcgcccaaaaagctcttcagtgctgacaaagtcaccaagagcacaatactagtcaatggtgtcatttgtaccgaaaacctaaccaatggaaatgctgaactgctaaaccaagggtgcatttgccatcagaatccaattaactcttgcaggcatgacttgtttgtacaaccagctacctcagttcccgcgcataacacacaccacgagaaccagcccaagcccagatttgaatgtaatcgacaaagtaataacctggacggaattattaacaaatctacctcagattgttgctcaaaagaggcagtttcctgcaaatcctcagagcctccagcaattccacaatggatttctcattcgggtgactatccacctggcgcatatacaactgaaaccctcggccccaaccctggtctgattcttcaagctttgaccctgtcaaatgccagtgatggcttcaatctggagcgcttggagatgctcggcgattcattcctgaagcatgcaatcacaacgtatctcttttgtacatacccagatgcccatgaagggcggctgtcttacatgaggagtaagaaggtcagcaactgtaatctttatcgccttggaaagaagaaaggtcttcctagtcgaatggtggtctccatatttgacccacctgttaattggctccctcctggctacgtggtaaatcaggacaaatacattgcagacaagagcgaaatgaaagacatgattgttaccagcgattggaattccttggagatgcaattttggactacctcattaccaagcacctttacgaagatccccgacagcattctcctggagtgttgacagacctgcgttcagcgcttgtgaataataccatcttcgcttctttagctgtgaaatacgactaccataaatatttcaaagc

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