LOCUS       XM_062495459            4546 bp    mRNA    linear   VRT 26-JAN-2024
DEFINITION  PREDICTED: Cinclus cinclus NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), transcript variant X4, mRNA.
ACCESSION   XM_062495459
VERSION     XM_062495459.1
DBLINK      BioProject: PRJNA1066473
KEYWORDS    RefSeq.
SOURCE      Cinclus cinclus
  ORGANISM  Cinclus cinclus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
            Passeriformes; Cinclidae; Cinclus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_085051) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_963662255.1-RS_2024_01
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 01/19/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4546
                     /organism="Cinclus cinclus"
                     /mol_type="mRNA"
                     /db_xref="taxon:127875"
                     /chromosome="6"
     gene            1..4546
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon."
                     /db_xref="GeneID:134045630"
     CDS             67..3177
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X4"
                     /protein_id="XP_062351443.1"
                     /db_xref="GeneID:134045630"
                     /translation="

MALFPAFAGAAQPGEPPAGSSEGSTRDLDWLSNPSFSAEDALLLHQRTTEVANLIPEKSPLIRTSSRSELSEESDTDESLKQTSKKRKKKKHHHSKKTKKKTKGDSSSSESDVDTKHIKDKGSGKSSGKEAAANLGKKASSVTSSRSIWLDDIQAPRADTFRIDKKPDPANWAYKSLYRGDIARYKRKGESCLGIDAKKHCITWDSSASKRKQAQSRPERYFTKNNVKMLSTDGILVCNKNSPSDPAAFIPVSHVETDDSSDTTEVNPLGIYDASTTVWLQGKGCKSADSESVNTQQTIQEPGIKLNSILMTKVEEYNKKVRENPRDINAWMEFISFQDELMRGPGPYASTGEQESRRKSLKLILEKKLAILERAIESNPSNVDLKLARLKLCTEFWEPPALIKEWQKLIFLHPNNPEMWKKYLLFCQSQFTTFSVSKINSLYGKCLTTLAAVQDGSMVSHPLLPGTEEAMLAIFIQQCHFLRQAGHSEKAVSLFQALIDFTFFKPDSVKDLPTRGQVEFFEPFWDSGEPRIGEKGARGWKAWMHQQEKGGWVVKPDDEDDEEIDEDQEIKDKTLPKWHIWLDIEYSREARHWLPWRPDKTKKETEEDCEDPERQVIQCLQAKKKKKLKAQGRKSKKLAKNFLKAPDNRNNLSLWKLYAYLEWLLGNTDDSRKVFDTALCTAGTGGLRSAQLCSLSLLYAQLEVEVLESIEGAVMSRAVHILTKLTENGPYVPYSGQVLPVNVLKARKTYEHALQDCLSRTPVSDQDQVNATDQLVNLVGCYALFQYLTVGIDAAVLIYTQASEKLEASGSQNCENTGENSGILNFPTALEAVTVLHTNLLRFHMKISVYPLNPLREALTEALKRYPSNQSLWRSYIHIQRKSHSASKARRFFDSVTRSSNSLEPWLFAIQAEQMRKKLTEKVQRADVGEIHCTIPETGLTNRIVALFEHAVQSENGTHCPLLWRMYLNFMASLGKKEKSKGLFYKALQNCPWAKVLYMDAVEYFPDDLQETLDLMTEKELRVRVPMEELDLLLEI"

     misc_feature    544..828
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(544..570,577..582,592..597,601..603,607..651,
                     658..666,670..678,700..708,718..723,727..732,739..759,
                     778..786,799..828)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1012..1917
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     polyA_site      4546
                     /gene="NRDE2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

ccggcgcgcccggcgccatcttgccgccggcggctcagggtggggggcggtgtcggcggccgagacatggcgctgttcccggccttcgccggggccgcccagcccggggagccccccgccggcagctccgagggctccaccagagatttagactggcttagtaacccaagcttctctgcagaagatgcactattactgcaccagcgcactacagaagttgccaatctcattcctgagaaatcaccattaataaggacttcttcaagatctgagttgtcagaggagagtgatacagatgagagtctgaaacagacaagtaagaaaaggaaaaagaaaaagcatcaccacagtaagaagacaaaaaagaaaaccaaaggagattccagtagcagtgaatcagatgtggacactaagcacatcaaggacaaaggaagtggcaaaagtagtggaaaggaagcagcagcaaatctaggtaagaaagcatccagtgttaccagcagtcgctctatttggcttgatgatatccaggcccccagagcagacaccttccggatagacaagaaaccagaccctgcaaactgggcctacaaatccttgtatcgtggggacattgcaaggtataaaaggaaaggagagtcctgtcttggcatagatgcaaagaagcactgtataacttgggatagttctgcatcaaaaaggaagcaagcacagagtcgacctgagcgctactttacaaagaacaatgtgaagatgctgagcacagatgggattcttgtttgtaataaaaattctccatctgatccagctgcttttataccagtttcccacgtggaaactgatgattcttctgacacaacagaagtaaatccccttgggatttatgatgcatcaaccacagtgtggctacaaggaaaagggtgcaagagtgcagacagtgagtctgtaaatactcagcaaacaattcaagagcctgggataaaactgaactccattttaatgacaaaagtggaagaatataacaagaaagtcagagaaaacccaagagatattaatgcttggatggaatttatttcctttcaggatgagttaatgagaggacctggcccttatgccagtacgggagagcaggaatcaaggagaaaatcactcaagttaatcttggaaaagaaactggccattttagagagggcaattgaaagcaatccaagtaatgttgatctaaaacttgccaggctgaagctttgcacagaattctgggaaccaccagctttgatcaaggaatggcagaagctaatttttttacatcccaataatccagagatgtggaagaaataccttctgttctgtcaaagtcagttcactactttttccgtctcaaagatcaacagtctctatggaaaatgtttgacaacactggcagctgtacaggatggcagcatggtatcccatcctctgctgcctggcacagaagaagctatgctggctatatttattcagcagtgccactttctgagacaggctgggcattctgagaaagcagtgtccttgtttcaggctctgattgacttcaccttctttaaacctgacagtgtaaaagatctgccaacaaggggacaggtggagttctttgaacccttttgggatagcggagagccacgaattggagaaaaaggagcaagaggctggaaagcatggatgcaccaacaagaaaagggtggctgggttgttaagcctgatgatgaggatgatgaagagatagatgaggaccaagaaataaaggataaaactcttcccaagtggcatatttggttggatattgaatattcccgtgaggcaaggcactggttaccttggaggccagacaaaaccaaaaaggaaactgaagaagattgtgaagatccagaaagacaggtaattcagtgtctccaagcaaaaaagaaaaagaagctaaaagcacaagggaggaagagtaaaaagttggccaagaatttccttaaagcacctgacaaccgaaacaacctttctctctggaaactctatgcctacctagaatggctgcttggtaacacagatgattccagaaaggtgtttgacacagctctttgcacagcagggacaggaggattgaggagtgcccagctctgcagcctcagcctgctttatgctcagctggaagtggaagtgctagaaagtatagaaggagctgttatgtcacgtgctgttcatatattgaccaaattgactgaaaatggaccatatgtgccctatagtggacaagtgttacctgtgaatgtcttgaaggctcgtaaaacatatgagcatgcactgcaagattgtttaagcagaacaccagtttctgatcaggatcaggtcaatgctactgatcagctggttaacctggttggttgttatgcactgttccagtatttgactgttgggattgatgctgcagtattaatatatacacaggcttcagaaaaacttgaagcttctggttcacagaactgtgaaaatactggagagaattctggcattctaaattttcccactgctcttgaagctgtcacagtgctgcatacaaatttactgagattccacatgaaaattagtgtttatcctttgaatccccttcgagaggcactaacggaggctctgaaacggtatcctagcaaccaatctctttggaggtcatacatccacatccaaaggaagtctcacagtgccagcaaagcacgaagattttttgatagtgtcacaaggtcttctaactctttagagccatggctgtttgcaatccaagcagagcagatgagaaaaaaactcacagagaaggtccagagggcagatgttggtgaaatacattgtactattcctgaaactgggttaacaaaccggattgtagcgctatttgaacatgcagttcagagtgaaaatggtacccactgtccactgctatggagaatgtatttgaactttatggcttcactaggaaaaaaagaaaaaagtaaaggattgttttataaagcgcttcaaaactgtccttgggcaaaggtactctatatggatgcagtagagtatttccctgatgatctgcaagagacgctcgatctaatgactgaaaaagaattgagagtgcgggtacctatggaagagctggatctactactagagatttaaaagaagaccatagcagagtggatgaagtacagaagttgcttccaaagctagcagttagatccgtatcttttcatacaggaactctgttgcgacttgggtactatgtacttggtatttttttgttgttaaatgttttgtataaattcctatcaaaatggagttctgctacctgcaagtattctggaatcaaagactgaactttgttcacaataatggatccatttctctgaagtattgctggctcccacagaaggataccatctttaaatagtctcctcttggaagttgccttcatttctgattctattgtttgaaattacattccctagggttcagtagaggttcagtacatgccaactatggcttgatgagcagcacaggaaatgaacatctgccaaatggatgctccactgtcctctagttggcagacttcagtaatttccttcagcgtggtatgcctgtgcatatgtaactgccaagtcaaacagctattacatctgtacattatactgtgagtaaaagctaaatttttgtttgagcaggcacctattttggtatgctttgacagatgaccattttaatataaatatctctgaaaaatatacctgaatatttgacaattaaaagtagttttttatttgatttaatagaactcgagtgtattaaaaatgaaaacatgtccataatgcatctctaaacacctcacttctaaacaaatttttgtaattgattacttgctttgactcaaatccaggcaattcttctaagagaagtagaggttggttctgcatttgattctcatcaagaaggcacagttttctatgattatttttaaagtagcttatattccaagagacttttagcaagctactagagaagtaatatgaaatatggtaacaatatgttacacatttattttgtaaaacagaacatgttgaaacatggaacagattgagacccaaggactcagagactggattttcatctgaaacaagtatacctgtagccacagaatacccaaaactgcttcagacatttttcatgagagagctaattgtcattagcagcactaaagcaattgggatcatccagctggtgagatcctattactcatgaagctatgtctggacaagacgtacaacttctaactcgggcctgccaccataatacaagatggaatacactgcagttcagactgcatttcatttattcctttctaaaattattttaaatattgcaggaagtatgtataattttatattacagcacttctgaagagtcttagaatattgatgaagttagaagtgatgctggtgttgctgtattgattcgtctttgtgaaaaatatagtttatttttcaaatcttta

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