LOCUS       XM_059059275            4665 bp    mRNA    linear   MAM 22-AUG-2023
DEFINITION  PREDICTED: Kogia breviceps NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), transcript variant X1, mRNA.
ACCESSION   XM_059059275
VERSION     XM_059059275.1
DBLINK      BioProject: PRJNA1006431
KEYWORDS    RefSeq.
SOURCE      Kogia breviceps (pygmy sperm whale)
  ORGANISM  Kogia breviceps
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha;
            Cetacea; Odontoceti; Physeteridae; Kogia.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081312) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_026419965.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/18/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4665
                     /organism="Kogia breviceps"
                     /mol_type="mRNA"
                     /isolate="mKogBre1"
                     /db_xref="taxon:27615"
                     /chromosome="3"
                     /sex="female"
                     /tissue_type="fibroblast cells from skin"
                     /dev_stage="juvenile"
                     /geo_loc_name="USA: La Jolla, CA"
                     /lat_lon="32.866232 N 117.25444 W"
                     /collection_date="2017-08-24"
     gene            1..4665
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 11 Proteins"
                     /db_xref="GeneID:131753678"
     CDS             24..3521
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_058915258.1"
                     /db_xref="GeneID:131753678"
                     /translation="

MALFPAFAGVSEEPESGGPRKELDWLSNPSFCVETITSLSQQTEEATAFVSEESLLTRSPLNSEPSDESDTNKKPKQTSRKKKKEKKKKRKHQHHKKTKRKRGQSSSSGSESYTDSEKDRSSRNIRGSKKESEKPNQENNATADIGRHFVWLEDIQALTGETFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGTSTEKKRSHKHVERYFTKKSVGLMNINGVAISSKTEPPSSESISFIPVKGAEDVVSPVTSWLNPLGIYDEATTQWLQGRGPSEQEPKQPDSQPSRENVLLKAKVEEFNRRVWENPRDIQLWMAFVAFQDEVMRSPGLYAIEEGEQEKQKRSLRLVLEKKLAILERAVESNPSSVDLKLAKLQLCAEFWEPSTLLKEWQKLIFLHPNNTALWQKYLLFCQSQFSTFSISKIQSLYGKCLSTLSAVKDGSILSHPELPGTEEAMFALFLQQCHFLRQAGHSEKAVSLFQALVDFTFFKPDSVKDLPTKGQVEFFEPFWDSGEPRAGEKGARGWRAWMQQQERGGWVVVSPDDDDDEPEDDDQEIKDKTLPRWQVWLAAERSRDHRHWRPWRPEKTKKQAEEDCEDPERQVLFDDIGQSLIRLSSPDLQFRLIAAFLQFLGVPSGFSPPASCLYLAMDENSIFDNGLYDEKPLTFLNLSFSGVSCVGRTDQLGCRHWTRGHSREGEEFIRSIFHLVMPLFSGKERSQLCFSWLRYEIAKVVWCLHTKNKKRLKSQGKNCKKLAKNLLKEPDNRNNFCLWKQYAHLEWLLGNTEDARRVFDTALGMAGSRELKERELWELGLLYAELEVELLPHVTGATPARAIHVLTRLTEDGAYGPYTGQVLAVHILKARKAYEHALQDCLGESCVSDPAPADSFSRLISLVKCFMLFQYLTIGIDAAVRIYEQVFAKHKVSVSAEGPGLEGGASPQSLSGALEAVALMHTSLLRFHTKVAVYPLAPLREALSEALKLYPGNQVLWRSYVQIQNKSHSASKTRRFFDAITRSAKPLEPWLFAIEAEKMRKRLVETVQRVDGREVYATIPETGLTHRIRALFENAMRSDYGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKVLYLDAVEYFPDEMQEILDLMTEKELRVRLPLEELELLLED"

     misc_feature    507..794
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(507..533,540..545,555..560,564..566,570..614,
                     621..629,633..641,663..671,681..686,690..695,702..722,
                     747..758,768..794)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    963..1961
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

aaaaggcggtgcggcctgtgatcatggcgctgttccccgcctttgcgggtgttagtgaggagcccgagagcgggggccccaggaaagaattagactggctgagcaacccaagcttttgtgttgaaaccataacatctctaagccaacaaactgaagaggccacagcctttgtttccgaagagtcgctactgaccaggagtcctctgaattcagagccttcagatgaaagtgacactaacaaaaagcccaaacaaacaagcagaaaaaagaagaaagagaaaaagaagaaaaggaaacatcagcaccacaagaaaacaaagaggaaacgtgggcagtcaagtagcagtggatctgagtcatatactgattctgaaaaggacagatcttccagaaacatcagaggcagtaaaaaggaatcagagaaaccgaatcaagaaaataatgccactgctgatattggacgtcactttgtttggcttgaggacattcaggctctgacgggagaaaccttcagaacagataagaagccggatcctgcaaactgggagtataagtctctttaccgaggagatatagcaagatacaagaggaaaggagactcctgccttggcattaaccctaagaagcagtgtatatcttgggaggggacttccacagaaaagaagcggtcacacaagcatgtcgagcgctactttacaaagaagagtgtgggattaatgaacattaacggagttgccattagcagtaaaactgaacctccctcatcggagtcgatctcatttatcccagtgaagggtgcagaggatgtggtttcccctgttacaagctggttgaaccctctggggatttatgatgaagccaccacgcagtggttacaaggccggggtccttcagagcaagaacccaagcagccagattcacagcccagcagagagaatgtgcttctcaaggccaaggtggaggagtttaacaggagggtttgggagaatcctcgagatattcagctgtggatggcatttgttgcttttcaggacgaggtcatgagaagtccgggcctgtacgccatcgaggaaggagagcaggaaaagcagaagcggtccctgaggctggttctggagaagaagctggccattctggaacgggccgtggaaagcaacccgagcagcgtggatctgaaactcgccaagctgcagctctgtgccgagttctgggagccctccactctgctcaaagagtggcagaagctgatattcttacatcccaacaatacagccctttggcagaaataccttttattttgccagagccagtttagcaccttttccatatcaaaaattcagagtctttatggaaaatgcttgagtactttgtctgctgttaaggacggcagcatcttgtctcaccctgagctgcctggcactgaggaggccatgtttgccctctttcttcagcagtgccacttcctgcggcaggctggtcactccgagaaggccgtctctctgttccaggccctggttgacttcaccttcttcaaacccgacagtgtgaaagacctgcctaccaaaggacaggtcgaattctttgagcccttttgggacagtggagagcccagggccggggagaagggcgcccgaggctggagagcgtggatgcagcagcaggagcggggcggctgggtggtcgtcagcccagatgatgacgatgatgaaccagaagacgacgaccaggaaattaaagataagactctcccccggtggcaggtctggcttgctgctgagcggtcccgagaccacagacactggcggccgtggcgccctgagaagaccaagaagcaggcggaggaagactgtgaggacccagagaggcaggtgttgtttgatgatattggacagtctctgatccgactttccagcccggatcttcagtttcggctgattgcagcctttctgcagttcttgggtgtgccttccggcttcagccctccggcctcctgcctctatctggccatggatgagaacagcatctttgacaatggactttatgatgaaaagcccttgacttttctcaacctttcattttccggcgtcagctgtgtcggacgcacggaccagctgggttgccggcactggaccaggggccacagtcgagagggcgaggagttcatccgcagcatcttccacctcgtgatgcctttgttttcaggcaaggagaggtctcagctctgcttctcctggttacggtacgagattgcaaaggtcgtttggtgtctgcacactaaaaacaagaagagattaaaatcacaaggcaagaactgcaaaaaactagccaagaatctccttaaggagccagacaaccgcaacaacttctgcctctggaagcagtatgcacatctggagtggttgctcggcaacacagaggatgccaggagagtgttcgataccgcgctcggcatggcagggagcagagagctgaaggagcgcgagctgtgggagctcggcctcctctacgccgagctggaggtggagctgttgccgcacgtgacaggggccaccccagcccgagccattcacgtactgaccagactgaccgaggatggggcctacgggccctacaccgggcaagtcttggccgttcacattttgaaagctcggaaggcttatgaacacgcgctgcaggactgtctgggggagagctgtgtgtccgatccggctcccgccgattccttcagccgcctgattagcctggttaaatgctttatgctcttccagtatttgaccatagggatcgacgctgctgtgcgaatatatgagcaggtatttgcgaagcacaaggtgtctgtttccgcagagggccctggcctggagggcggtgccagcccccagagcctgagcggtgccctcgaggccgtcgccctgatgcacacgagcctcctcagattccacacgaaagtcgccgtctaccctctggcgcccctgcgagaggctctctcggaggctttgaagctgtatccgggcaaccaggttctttggaggtcgtacgtacagattcagaataagtcccacagtgccagtaagaccagaagattcttcgatgcgatcaccaggtctgccaaacccttggagccgtggttgtttgccattgaagctgagaaaatgaggaaaagactggtggaaactgtgcagagggtagatggtagagaggtctacgccaccattcccgagaccggcctgacgcatcggatcagagccctatttgaaaacgccatgcggagtgactacggcagccagtgccccttactgtggaggatgtatttgaattttttggtttccttaggaaataaagaaagaagcaaaggtgtgttctacaaagcacttcagaattgtccttgggcaaaggtgctgtacctggatgccgtggagtacttccccgatgagatgcaggagatcctggacctgatgacggagaaggagctccgggtgcgcctgccgctggaggagctggagcttctgcttgaggactagagaccaggaggggagtggggcgtgcctgcctccggggcccagcgcctgccccgtgggagccaggaggtaccagaagagacggggacacgtgcgtgtgagcgtgttaagacctctgcctttggagtttctttcttgatagtttttgtctgggttattggtctctcacctcttgcacattttttgcgtgtgcaaatgacacaaaagccattgttttgcatattatatatgtatgtgtatatatgtgcatagacaggaatcatgctaagtgataactgaacctgtcatggttggtgtgtgagttctcgtttggtccactgttcccctgcccagccagcgccagccctgctggggtgaatgttccttctcggttggcatccttggtggtcctgccagctctcctgggtcttgcagtcaaaaaaaggtctggttactcaatactaggacttcctcctctgggctggttagcagattttacccttatcttcagacgagagcagtggggggtcgtttaaaacttggtattctcacctgtagcaaatgtgttttcttattattccctgaaccctattcagtgatgtcctcgactatggcccgagcagccagcatcgcttgggagcaatgtagaccctcaggcccgtccccagccctgctgtcagaacctgggctctaataggacgccctgtgaggggactttgtgtgtacataactgtgtagagaaagcactgcctgaacaaataaggaccccgctgcgggaagctcaccaacagccactgtcgtggagaacggagtgagcgccttcctaccaaacccggcgctgcctgtgacacgtgccgaaggtggctttcagcggtgttgaccacgctctcattctgatttccaggaaccgagttatatttgactgagaggaaattgctttagcttgtctgaggtcctgctttttaaaaagtggacagcttctctggcttttttggtttttttttttaatcatgctctctagaattgctgaaagcatatttccttggcacctcatccagaaaagccagtgctgtggaatagaattttggctagaaatcgatggacactggttgggaaaaagcagcagagggcagcacagctgcagcagcggtccccgacctttttggca

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