LOCUS       XM_058748689            3230 bp    mRNA    linear   VRT 08-AUG-2023
DEFINITION  PREDICTED: Onychostoma macrolepis NRDE-2, necessary for RNA
            interference, domain containing (nrde2), transcript variant X4,
            mRNA.
ACCESSION   XM_058748689
VERSION     XM_058748689.1
DBLINK      BioProject: PRJNA999377
KEYWORDS    RefSeq.
SOURCE      Onychostoma macrolepis
  ORGANISM  Onychostoma macrolepis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Cyprinidae; Acrossocheilinae; Onychostoma.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_081171) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_012432095.1-RS_2023_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/02/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3230
                     /organism="Onychostoma macrolepis"
                     /mol_type="mRNA"
                     /isolate="SWU-2019"
                     /db_xref="taxon:369639"
                     /chromosome="17"
                     /sex="female"
                     /tissue_type="muscle"
                     /dev_stage="adult"
     gene            1..3230
                     /gene="nrde2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 Protein"
                     /db_xref="GeneID:131522863"
     CDS             143..3142
                     /gene="nrde2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X2"
                     /protein_id="XP_058604672.1"
                     /db_xref="GeneID:131522863"
                     /translation="

MQGSTVTVYKRKGGSCLGLDIRMQAVNWNDGGPEKKRVDKKHERYFCPSTRRLLRSDGLPALPVLSEGIAVSSDTYIKLSACTEEQGSSTQAPVSWVNPLGIYDCGTSLWLEGKGQPEVKRDQQDVEAQGSSSTLLSARVEEFNRKLRENPTDTQLWLDFVHFQDELAFGSSSFSVATDTDNDGEMKKMSLRAVLEKKLSIVDRAVESNPANVDLKLEKLHLCKELWEPATLQKEWKKLVFIHPNSAPLWRKYLLFTQSHFSTFSVSKVNSMFGKCLSTLSAVQDGSMVSHPPLPGTQEDLLDIFLQQCHFLRQAGHTEKATCLFQALLDFTFFKPDSVKDLPTRQQVDFFEPFWDSGEPRIGERGARGWKAWMLQQERGGWVIPPEPDEDDEEEQDDSEIKDKTWPKWKIWLDVEASREANHWLPWRPDKTKGQSEEDCEDPDRQVLFDDIGPSMIRVDRVDLQLQLILSFLQFLGLPGPSGRFSTTSSSNILLDDLAFLEEGPDPERPLTSHDLPLAGTCAVGHMTFLSDCRRQAGLCKAGEEFLQNVLQQTLPLVSVQDQATITLCWLQYEKLKVLRCLRSGNKRRLKSQGKRSKRLAKRLLKEPDNRGSLALWREYAHLEWLLGNLEEARKVFDTALGMGVTRGLNDPVLCNLCFLYAQLEVEQALNSGTVPTSKAVYILTKLAEGAAYTPFAGQINPVAILKARKTYEQALLSFLPEQSTGSNAAASKKFHRMSSLVGCFGLFQYLTVGIDAADAVYSQAIQKLISSNLNLEVTHGSLRRPKAFSDWESVAVQHVALLRHHASTSVFPLSRLRLALTDALSLLPFSASLWQLYLQTENRYHSAGRARRFFHSVAKKTNSVVPYLFAVTAEQRLRQMLDSVQRSHLPGEALPTIPNNGLSNRIRCLFENATATEHGAHCPLLWRMYLNFMVCDGNAERGSGIFYKALQAVPWVKGLYMDAVQLFPERVQEFLDLMTEKELRLRVPMEEVEILLED"

     misc_feature    <167..379
                     /gene="nrde2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    566..1573
                     /gene="nrde2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

gatgacctccagacccccactgactcccccttctgtattgacagaagagctgaccgtgccaactgggaatacaaatccctctataggggagacatagccaggtcagccagtctcagcagcagcaggtgccagacgctccataatgcaggggagtactgtgaccgtgtataagaggaagggaggctcatgcctggggttagacatcaggatgcaggctgtgaactggaacgatggtggcccagagaagaagcgagtggacaagaaacacgaacgctatttctgtccctccacccgtcggctgctccggtcagatggtctgcctgctttacccgtactctctgagggcattgccgtcagctctgatacttacatcaagctctcagcctgcactgaagagcagggctcttccacccaggcacccgtatcgtgggtaaatccgctgggcatctatgactgtggaacctctctttggctggagggcaagggtcaaccagaggtcaagagagatcagcaggacgttgaggctcaagggagcagcagcacccttctgagtgcacgggtggaggagtttaacaggaagctacgggagaatcctacggacacccagctgtggctggactttgtacacttccaggatgaactggcctttggttctagttcattctcagttgccactgacactgacaatgatggtgagatgaagaagatgtctcttcgtgccgtgctggagaagaagctgtccattgtggacagggcagtggaaagtaaccctgccaacgtggacctgaaactggagaaactccatctgtgcaaagaactatgggagcctgccaccctgcagaaagagtggaagaaactagtgttcatccatccaaacagcgcgcctttatggaggaagtatcttctcttcacacagagtcatttcagcacgttctctgtgtcaaaagtcaacagcatgttcggaaagtgtttaagcacgctcagtgcagtccaagatggcagtatggtgtctcaccctccgcttccaggcactcaggaagacctcttagatatctttctacagcagtgccatttcctgcggcaggcgggtcacaccgagaaagctacgtgtctcttccaagcccttctggacttcactttcttcaagccagacagtgtgaaagaccttcccactagacaacaggtggatttttttgagccattttgggacagtggagagcccaggattggggaacggggagctcggggatggaaggcttggatgcttcagcaggagagaggaggatgggtgattccacctgagccagatgaggatgacgaagaagagcaggacgactccgagatcaaagacaagacctggcctaagtggaagatctggttagatgtagaggcatcacgagaggcaaaccactggttgccatggagaccagataaaaccaagggccaatcagaagaggactgtgaggaccccgacaggcaggtcttgtttgatgatattggcccatctatgattcgtgtggacagagtagatctccagctgcagttgatcctgtcattcctgcagttcctaggtctgcctggaccttcaggaaggttctctacaacctcttcctcaaacattctattggatgatctcgccttccttgaagagggcccagacccggagcgaccactgacctctcatgacctcccattggctgggacctgtgcagtgggtcacatgacatttctgagtgactgcaggagacaggcagggttgtgtaaagcaggggaggagtttctccagaacgttttacagcaaactctcccactcgtgtctgtacaggatcaagctaccattaccctctgctggctgcagtatgagaaactaaaggtgctgagatgtctacgcagtggaaataaaaggcgactgaagtctcaggggaagcgtagtaaacggctagcaaaacgactgctaaaagagccagataacaggggcagcctggcactttggagagagtatgcccatctggagtggcttctgggtaatctggaggaggcacgcaaagtatttgacactgccttgggcatgggcgtgactagaggccttaatgatcctgttctctgtaacctctgctttctctatgcccagttagaggtagagcaggccttaaacagtgggacagtccctacttccaaagctgtctacattcttactaaattagccgagggtgctgcctacacacctttcgctggtcagatcaacccagtggccatattaaaggccagaaagacctatgagcaggccctcttgagctttttacctgagcagagcacaggcagcaatgctgcagcttcaaagaaattccacaggatgtccagcctggtaggatgttttgggctttttcagtacctcacagtggggatagatgcagctgatgctgtgtacagtcaggccatccaaaaactgatttccagcaacttgaatttagaagtaacacatggatctctgaggagacccaaggccttttcagactgggagtctgttgctgtccagcatgtagcactgctgcgccaccacgccagcaccagtgtgtttcctctctctcggctaagattggcacttacagatgccctctccttactgcccttcagcgcctcattatggcaactctaccttcaaacagagaaccgatatcacagcgctggccgtgcccgcaggtttttccacagtgtggcaaagaaaactaacagtgttgtgccgtatcttttcgccgttactgcagagcaacgactgagacagatgctggactctgttcagaggtctcatcttcctggagaagccctgcccaccataccaaataatggtcttagcaaccgtatccgctgtctgtttgaaaatgctacagcaacagaacatggggcccactgtcctctgctctggagaatgtatctgaacttcatggtatgtgatgggaatgcagagaggggcagtggaatcttctacaaggccctacaggcagtgccctgggtaaagggcttgtacatggacgcagtgcagctgttccctgaacgtgtgcaagagtttttagatcttatgactgagaaggagttgcgtctcagagtgcccatggaggaggtggaaatcttgctggaggactaaccatcaaaacccttcccataacaacagcaaaaaaaaaaaagaaaagaaaaaggttttatttatttttattttggaaataaatgatata

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