2024-09-08 11:17:34, GGRNA.v2 : RefSeq release 225 (Jul, 2024)
LOCUS XM_056122746 5217 bp mRNA linear MAM 09-OCT-2023 DEFINITION PREDICTED: Sorex fumeus argonaute RISC catalytic component 3 (AGO3), transcript variant X1, mRNA. ACCESSION XM_056122746 VERSION XM_056122746.1 DBLINK BioProject: PRJNA972655 KEYWORDS RefSeq. SOURCE Sorex fumeus (smoky shrew) ORGANISM Sorex fumeus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae; Soricinae; Sorex. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_026606104) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_029834395.1-RS_2023_10 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.2 Annotation Method :: Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 10/04/2023 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..5217 /organism="Sorex fumeus" /mol_type="mRNA" /db_xref="taxon:62283" /chromosome="Unknown" gene 1..5217 /gene="AGO3" /note="argonaute RISC catalytic component 3; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 34 Proteins" /db_xref="GeneID:130031410" CDS 117..2699 /gene="AGO3" /codon_start=1 /product="protein argonaute-3 isoform X1" /protein_id="XP_055978721.1" /db_xref="GeneID:130031410" /translation="
MEIGSAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVASTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"
misc_feature 333..617 /gene="AGO3" /note="N-terminal domain of argonaute; Region: ArgoN; pfam16486" /db_xref="CDD:465134" misc_feature 645..797 /gene="AGO3" /note="Argonaute linker 1 domain; Region: ArgoL1; pfam08699" /db_xref="CDD:462567" misc_feature 798..1160 /gene="AGO3" /note="PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille; Region: PAZ_argonaute_like; cd02846" /db_xref="CDD:239212" misc_feature order(954..956,999..1001,1041..1043,1053..1055,1107..1109, 1128..1130,1134..1136) /gene="AGO3" /note="nucleic acid-binding interface [nucleotide binding]; other site" /db_xref="CDD:239212" misc_feature 1293..2570 /gene="AGO3" /note="PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the...; Region: Piwi_ago-like; cd04657" /db_xref="CDD:240015" misc_feature order(1704..1706,1716..1718,1752..1763,1770..1772, 1794..1796,1803..1805,1815..1817,1827..1829) /gene="AGO3" /note="5' RNA guide strand anchoring site [active]" /db_xref="CDD:240015" misc_feature order(1908..1910,1914..1916,2124..2126,2538..2540) /gene="AGO3" /note="active site" /db_xref="CDD:240015" ORIGIN
ccccgcctccgggccggctgagggtccccgtggcgccgcgtcgccccctgcgcggtctcctcgcccccccgtggcgggcgcccttctcgctcccggcactctccccagctccatgaatggaaatcggctccgcaggacccgttggggcccagcccctactcatggtgcccagaagacctggctatggcaccatgggcaaacccattaaattgctggctaactgttttcaagttgaaatcccaaagattgatgtctacctctatgaggtagatattaaaccagacaagtgtcctcggagagtgaacagggaagtggttgactcaatggttcagcattttaaagttactatatttggggatcgtagaccagtttatgatggaaaaagaagcctttatacagccaatccacttcctgtggcatctactggggtagatttagatgttactttaccaggggaaggtggaaaagatagacctttcaaggtgtcaatcaaatttgtctctcgggtgagttggcatctgctacatgaagtactgacaggacggaccttgcctgaaccactggaattagacaagccaatcagcactaatcctgtccatgctgtcgatgtggtgctacgacatctgccctccatgaaatatacccctgtggggcgttcctttttctcagctcctgaaggatatgaccaccctcttggagggggcagggaagtatggtttggatttcatcaatctgttcggcctgccatgtggaaaatgatgctcaatattgatgtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgatattcataatattgatgaacaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagattaaaggtctgaaggttgaagtaactcattgtggaacaatgagacggaaataccgtgtttgtaatgtaacaagaaggcctgccagtcatcaaacctttcctttacagttagaaaacggccaaacagtggaaagaacagtagcacagtatttcagagaaaaatacactcttcagttgaagtacccacaccttccctgtctgcaagtgggacaggagcagaaacatacatacctgccgctagaagtctgtaatattgtggcaggacagcgatgtattaagaagctaacggacaatcagacttccacaatgatcaaagccacagcaagatctgcacccgatagacaagaagagattagcagattggtaagaagcgcaaattatgaaacagatccatttgttcaggagtttcagttcaaggttcgggatgagatggcccatgtaacaggacgtgtacttccagcaccgatgcttcagtatggaggacggaatcggacagtagcaacaccaagccacggagtctgggacatgcgagggaaacagttccacacaggagttgaaattaaaatgtgggcaatagcttgttttgccacacagaggcagtgcagagaagaaatattgaagggtttcacagaccagctgcgtaagatttctaaagatgcaggcatgcccatccagggccaaccttgcttctgcaagtacgcacaaggtgcagacagcgtggagcccatgttccggcatctcaaaaacacttactctgggctgcagctcatcattgtcatcctgccaggaaagacaccagtgtatgcggaagtgaaacgtgtaggagacacacttttggggatggcgacccagtgtgtccaagtcaagaatgtaataaaaacttctcctcagactctctcaaacctgtgcctaaagataaatgttaaacttggagggattaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatatttttaggagcagatgtcactcatccacccgctggtgatgggaagaagccttccattgctgctgttgtaggtagtatggatgcccaccccagcagatactgtgccaccgtcagagttcagagaccccgacaggagatcatccaggatctggcttccatggtccgagagctgctcattcagttttataagtcaactcgcttcaaacctacgcgcatcatcttctatagggatggtgtgtcagagggacaattcaggcaggttttatattatgaactactagcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtagttcagaagaggcatcacactcgattattttgtgccgataggacagaaagggtcggaagaagtgggaatatcccggctggaaccacagttgatacagatatcactcacccatatgagtttgacttttacctctgtagccatgccggaatacagggtaccagtcgcccttcacactatcacgttttatgggatgataactgctttactgcagatgaacttcagctgctcacttaccagctctgccacacctacgtgcgctgtacacgatctgtttctatacctgcaccagcttattatgctcacctggtggcattcagagccagatatcatcttgtggacaaagaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatggtcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaaaagtccaagaatttgctttgagcagaagaactgaagatgcatcaatgtgcaacgttcaccgtgtgtttcccatggaatcagtttgggggggtaggggcgatgcctccagccatccggaagccaacactgtgcgggggtcgggtctgatctttgtgccgatagaagtacgattgtttacttcatcaaggaaaacagcaccattatgcaatatgaaaccagccaactgcttttttgtgcagtctcctgtaggaaatactgcgattgttctgttttcgttttcttatagtctaatcctttcaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaacaaaaacaaaacaaaaaaaagttgatggtttaaaaaaaaacccacctacagtgaataatcaaagtgatttttcacagctctgtgtgcaaaaaaattaatgtggattcatgtcttgtcaaaagtatattttaaatatatacatactttatatgcatatatatctgcttctacgttgataatagatatatatgtatcagtgtatatatttcatgtgcattccaatgggggaactttagtccctatccctgtaccctcaccaccgctttcctttctctctctctacctccctggccaacattacctacatttacccccccaagtgacatttcagtgttcatgtatgtggttcatttgtatatgaagcatggaaaattttatttttatttttcacagcctactcttgtctcttctctcatagacaattctgagtcccaaaatcttgataatgttttcttaagaaacagaattatcttctatagatgttttcgtgagaatgtgtctgccccacctgctttgaagttacattcgccccgtgtacggtgtgtacagaaatagcagtgacctgttgttttcctttattcttttattcagttaaagctgctataaatataaaaccttgtcagtagtggtaatactttctctctacaagtattatgtacacaaaagctttctgtttctgttgtttctacatggaaatcccttaaagcttttttataaacagcaaatattttaaatgaacagtcaggcagcctctcaaattgggtagaaagagagaaggggttgtttgaggggtcctgtcatttttttttctttcctagtttacttgctgcctctcataccttaatgtgattttcatatatatatttttatatatatgtgtatatatatataaacatatatgtatgttttgaagtttagctttcttttctatatattagaatagtgctttaataattataggattgtattgcaacatttttatagagatataatcatgtttattttaagaactgacagttgtttttgctatcttttggtgcaataagcagttttaaaggaaagtggtgtctctatgacatctttgccacagatagtgggagaagcgggcacctttataattttaattttaaaagggcaaagtaatacagccttaatttcagaaggaaagttttgtaattttcaaatttaatgcatgccttttaaaaattataatgaaaatgaaggaagttgaatttcctaaatgagtctgacttggaatattagaaataaagttgaactttgacagtgaacagcttaagattaagaggacatttaaattatttggaaagagatcattttttattgaaggctgatagtggctaagtacccatttttgtgtattgaaataaatcggaaagatataaaaatgattctattttttggtttaggggcctcacccagaggtgttcaggggctatttccagtgctcccagttcagggctactggcagtgcttggggtaccctgtggtactagagatagaactggggatttctgcatgctctacatatgcactaaccttttgagatttatccctggcccttaaaatgatatttttaaaaacagttttttcagttatcacctgcgtgactttgcttttaaaattagggtgatgatggcaaaagaagttagaatgtcagtaactttgagttaagtcacagaaatgtagaagataagttttgcaaaacttttgatcagttttactgatactaaaaagtactataaagctgtcaaaaccaacttcattggtaacattggatttaggagagctttgcactttgtaactcataaaaactgcattaaatttttcttttttgcactagttcaaagcatagatattatagattgtttccagtgggcattgttgctgacttttcagaatatatctgcatgtgaaaaggaatggtgatttttttagtttctattatctgtaatccactcattgccaatttactgtattttgagcctaaaatctgagcccctgtcctccaacaggtatgaaatctttgtccctctgccataaaaatgagaaagtactgtattttgtatgtttattatatagaagtgtctgaaatgcggttgacaacactattccagagctctttacatgcgatgatacttgtgtagt
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@meso_cacase at
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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