2024-05-02 21:38:53, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS XM_054538955 3510 bp mRNA linear PRI 11-APR-2023 DEFINITION PREDICTED: Pongo abelii NLR family pyrin domain containing 12 (NLRP12), transcript variant X3, mRNA. ACCESSION XM_054538955 VERSION XM_054538955.1 DBLINK BioProject: PRJNA944618 KEYWORDS RefSeq. SOURCE Pongo abelii (Sumatran orangutan) ORGANISM Pongo abelii Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_072004) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_028885655.1-RS_2023_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.1 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/06/2023 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..3510 /organism="Pongo abelii" /mol_type="mRNA" /isolate="AG06213" /db_xref="taxon:9601" /chromosome="19" /sex="male" /tissue_type="fibroblast" gene 1..3510 /gene="NLRP12" /note="NLR family pyrin domain containing 12; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 3 long SRA reads" /db_xref="GeneID:100449374" CDS 191..3208 /gene="NLRP12" /codon_start=1 /product="NACHT, LRR and PYD domains-containing protein 12 isoform X3" /protein_id="XP_054394930.1" /db_xref="GeneID:100449374" /translation="
MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGRMEKAGPLEMAQLLITHFGPEEAWKLALSTFERMNRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQAQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPCTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLISSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKPPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQMSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGADVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGERGAGPDQDVTKLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWEVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFGCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKHCRSAQVLHLYGTTYSADGEDRARCSAGVHTLLVQLRPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKKCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMTLLCEGLRHPRCRLQMIQLKICHLTAAACEELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSAVLQANHNLRELDLSFNDLGDWGLWLLAKGLQHPACRLQKLWLDSCGLTAKACKTLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC"
misc_feature 227..466 /gene="NLRP12" /note="Pyrin death domain found in NALP proteins; Region: Pyrin_NALPs; cd08320" /db_xref="CDD:260032" misc_feature 575..790 /gene="NLRP12" /note="Fish-specific NACHT associated domain; Region: FISNA; pfam14484" /db_xref="CDD:433982" misc_feature 824..1333 /gene="NLRP12" /note="NACHT domain; Region: NACHT; pfam05729" /db_xref="CDD:428606" misc_feature 1565..1726 /gene="NLRP12" /note="NOD2 winged helix domain; Region: NOD2_WH; pfam17779" /db_xref="CDD:436037" misc_feature 1730..2074 /gene="NLRP12" /note="NLRC4 helical domain HD2; Region: NLRC4_HD2; pfam17776" /db_xref="CDD:436035" misc_feature 2252..3127 /gene="NLRP12" /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cd00116" /db_xref="CDD:238064" misc_feature order(2252..2254,2261..2263,2267..2269,2276..2278, 2282..2284,2336..2338,2345..2347,2351..2353,2360..2362, 2366..2368,2423..2425,2432..2434,2438..2440,2447..2449, 2453..2455,2507..2509,2516..2518,2522..2524,2531..2533, 2537..2539,2594..2596,2603..2605,2609..2611,2618..2620, 2624..2626,2678..2680,2687..2689,2693..2695,2702..2704, 2708..2710,2765..2767,2774..2776,2780..2782,2789..2791, 2795..2797,2849..2851,2858..2860,2864..2866,2873..2875, 2879..2881,2936..2938,2945..2947,2951..2953,2960..2962, 2966..2968,3020..3022,3029..3031,3035..3037,3044..3046, 3050..3052,3107..3109,3116..3118,3122..3124) /gene="NLRP12" /note="Leucine-rich repeats [active]" /db_xref="CDD:238064" misc_feature order(2270..2275,2444..2446,2615..2617,2699..2701, 2870..2872,2948..2950,2954..2956,3032..3034,3119..3121) /gene="NLRP12" /note="Substrate binding site [chemical binding]; other site" /db_xref="CDD:238064" misc_feature 2336..2422 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" misc_feature 2423..2506 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" misc_feature 2507..2593 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" misc_feature 2594..2677 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" misc_feature 2678..2764 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" misc_feature 2765..2848 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" misc_feature 2936..3019 /gene="NLRP12" /note="leucine-rich repeat [structural motif]; Region: leucine-rich repeat" /db_xref="CDD:275380" ORIGIN
tgaagagtgagaaagcattatttcagcaaaaggtctttcctccctcgctcactcctcaaaccactggctcagcctctccgcccgctgcctgtgaatgatgcaatggaaggtgtgctggggtcgccccgtgtcccgtgcataggaacatctcagcctccaggtcctctcctttggggctcacggcacccccatgctacgaaccgcaggcagggacggcctctgtcgcctgtccacctacttggaagaactcgaggctgtggaactgaagaagttcaagttatacctggggaccgcgacagagctgggagaaggcaagatcccctggggacgcatggagaaggccggtcccttggaaatggcccagctgctcatcacccactttgggccagaggaggcctggaagttggctctcagcacctttgagcggatgaacaggaaggacctgtgggagagaggacagagagaggacctggtgagggacaccccacctggtggcccgtcctcacttgggaaccagtcaacatgccttctggaagtctctcttgtcactccaagaaaagatccccaggaaacctacagggactacgtccgcaggaaattccggctcatggaagaccgcaatgcgcgcctaggggaatgtgtcaacctcagccaccggtacacccggctcctgctggtgaaggagcactcaaaccccatgcaggctcagcagcagcttctggacacaggccgtggacacgcgaggaccgtgggacaccaggctagccccatcaagatagagaccctctttgagccagatgaggagcgccccgagccaccgtgcaccgtggtcatgcaaggcgcggcagggataggcaagtccatgctggcacacaaggtgatgctggactgggcggacgggaagctcttccaaggcagatttgattatctcttctacatcaactgcagggagatgaaccagagtgccacggaatgcagcatgcaagacctcatctccagctgctggcccgagcccagtgcgcctctccaggagctcatccgagttcccgagcgcctccttttcatcatcgacggcttcgatgagctcaagccttctttccacgatcctcagggaccctggtgcctctgctgggaggagaaaccgcccacggagctgcttcttaacagcttaattcggaagaagctgctccctgagctatctttgctcatcaccacacggcccacggctttggagaagctccaccgtctgctggagcaccccaggcatgtggagatcctgggcttctctgaggcagaaaggaaggaatacttctacaagtatttccacaatgcagagcaggcgggccaagtcttcaattacgtgagggacaacgagcctctcttcactatgtgcttcgtccccctggtgtgctgggtggtgtgtacctgcctccagcagcagctggagggtggggggctgttgagacagatgtccaggaccaccactgcggtgtacatgctctacctgctgagtctgatgcaacccaagcccggggccccgcgcctccagcccccacccaaccagagaggactgtgctccttggccgcagatgggctctggaatcagaaaatcctatttgaggagcaggacctccggaagcacggcctagatggggcagacgtctctgctttcctcaacatgaacatcttccagaaggacatcaactgtgagaggtactacagcttcatccatttgagtttccaggaattctttgcagctatgtactatatcctggacgagggggaacgcggggcaggcccagaccaggacgtgaccaagctgttgaccgagtacgcgttttctgaaaggagcttcctggcactcaccagccgcttcctgtttggactcctgaacgaggagaccaggagccacctggagaagagtctctgctgggaggtctcgccacacatcaagatggacctgttgcagtggatccaaagcaaagctcagagcgacggctccaccctccagcagggctccttggagttcttcggctgcttgtacgagatccaggaggaggagtttatccagcaggccctgagccacttccaggtgatcgtggtcagcaacattgcctctaagatggagcacatggtctcctcgttctgtttgaagcactgcaggagcgcccaggtgctgcacttgtatggcaccacttacagcgcggacggggaagaccgggcgaggtgctctgcaggagtgcacacgctgttggtgcagctcagaccagagaggaccgttctgctggacgcctacagtgaacatctggcagcggccctgtgcaccaatccaaacctgatagagctgtctctgtaccgaaatgccctgggcagccggggggtgaagctgctctgtcaaggactcagacaccccaactgcaaacttcagaacctgaggctgaagaagtgccgcatctccagctcagcctgcgaggacctctctgcagctctcatagccaataagaatttaacaaggatggatctcagtggcaacggtgttggattcccaggcatgacgctgctgtgcgagggcctgcggcatccccgatgcaggctgcagatgattcagctgaagatctgccacctcactgctgctgcctgtgaagagctggcctcaactctcagtgtgaaccagagcctgagagagctggacctgagcctaaatgagctgggggacctcggggtgctgctgctgtgtgagggcctcaggcatcccacgtgcaagctccagaccctccggttgggcatatgccgattgggctctgccgcctgtgagggtctttctgcggtgctccaggccaatcacaacctccgggagctggacttgagtttcaacgacctgggagactggggcctgtggttgctggctaaggggctgcaacatcccgcctgtagactccagaaactgtggctggatagctgtggactcacagccaaggcttgtaagactctttacttcaccctggggatcaaccagaccttgaccgacctttatctgaccaacaacgccctaggggacacaggtgtccgactgctttgcaagcggctgagccatcctggctgcaaactccgagtcctctggttatttgggatggacctgaataaaatgacccacagtaggttggcagcgcttcgagtaacaaaaccttatttggacattggctgctgaatagtcctatctgctggctctcccctgagatctggacagaggaagatgggagggtgctcatcacccctacagcataatgatcatgctccttcctagagacaaactcatgcagattgagatcagaagtccctctgcttgggatcaaattaatgtttgacagagctggccaggcatggtggctcatgtctgtaatcccagcacttcgagaggccgaggcaggtggatcacgaggtcaggagtttgagatcagcctggccaagatggtgaaaccctgtctctactaaaaataaaaaaaaaaatta
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]