LOCUS       XM_051780801            8418 bp    mRNA    linear   VRT 26-FEB-2023
DEFINITION  PREDICTED: Manacus candei lymphocyte activating 3 (LAG3),
            transcript variant X1, mRNA.
ACCESSION   XM_051780801
VERSION     XM_051780801.1
DBLINK      BioProject: PRJNA892944
KEYWORDS    RefSeq.
SOURCE      Manacus candei (White-collared manakin)
  ORGANISM  Manacus candei
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
            Passeriformes; Pipridae; Manacus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_026138062) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_025592945.1-RS_2023_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/25/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8418
                     /organism="Manacus candei"
                     /mol_type="mRNA"
                     /isolate="608988"
                     /isolation_source="Blood/tissue"
                     /db_xref="taxon:415023"
                     /chromosome="Unknown"
                     /ecotype="Guabito, Panama"
                     /geo_loc_name="Panama: Bocas del Toro, 8 km SW of Guabito"
                     /lat_lon="9.47 N 82.67 W"
                     /collection_date="1994-04-28"
     gene            1..8418
                     /gene="LAG3"
                     /note="lymphocyte activating 3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     Proteins"
                     /db_xref="GeneID:127468040"
     CDS             6390..7910
                     /gene="LAG3"
                     /codon_start=1
                     /product="lymphocyte activation gene 3 protein isoform X1"
                     /protein_id="XP_051636761.1"
                     /db_xref="GeneID:127468040"
                     /translation="

MRLVSLVLFLTFALLAFGAGHILAGLAEGESREQKMWVREGSSAVLPCHWSPRKMRKSLKQLPDKTSVQWKRHGGSVHQESHGVLEVGYSGLQKTALLMKPRVSLQDSALHNGNFSLRIDPVRSEDAGLYEARVEYNSEVHSCHVELGVVTVTLSPPNPVEENELLLMSCNSSYRASLVEICWFHNGHLGPTSRTFCSLSGALSILRPAMSDAGSWRCQLRYSDNEIISATYDLQILGFDGPTNPVVYAAAGSAAHLPCSLSYLPSSFQMNMVTAHWSHLAGGHLQDWDIFQNLSNRSFPLHLPVVGPGDAGQYRCAVSVGHKTISREVTLAVVTVTPSIQGPVSEGSRLQLICSLTHSRGHERFQWKHLGSVPTKSKLAVATPQNLEGNSAQMGPILKIPKVSQKDTGTWECSVYGPEGQLGGVEYKLQITSAQVSSPPAVFSGQVTFGLTLTLFLLLAVCVVALALQKRAQTPAFSALEGMIGVPGPWKLMKENQKGKIQQTEC"

     misc_feature    6489..6830
                     /gene="LAG3"
                     /note="Immunoglobulin like; Region: IG_like; smart00410"
                     /db_xref="CDD:214653"
     misc_feature    6519..6533
                     /gene="LAG3"
                     /note="Ig strand B [structural motif]; Region: Ig strand
                     B"
                     /db_xref="CDD:409353"
     misc_feature    6588..6602
                     /gene="LAG3"
                     /note="Ig strand C [structural motif]; Region: Ig strand
                     C"
                     /db_xref="CDD:409353"
     misc_feature    6732..6746
                     /gene="LAG3"
                     /note="Ig strand E [structural motif]; Region: Ig strand
                     E"
                     /db_xref="CDD:409353"
     misc_feature    6774..6791
                     /gene="LAG3"
                     /note="Ig strand F [structural motif]; Region: Ig strand
                     F"
                     /db_xref="CDD:409353"
     misc_feature    6828..6839
                     /gene="LAG3"
                     /note="Ig strand G [structural motif]; Region: Ig strand
                     G"
                     /db_xref="CDD:409353"
     misc_feature    6843..7058
                     /gene="LAG3"
                     /note="Immunoglobulin domain; Region: Ig; cl11960"
                     /db_xref="CDD:472250"
     misc_feature    6885..6899
                     /gene="LAG3"
                     /note="Ig strand B [structural motif]; Region: Ig strand
                     B"
                     /db_xref="CDD:409353"
     misc_feature    6927..6941
                     /gene="LAG3"
                     /note="Ig strand C [structural motif]; Region: Ig strand
                     C"
                     /db_xref="CDD:409353"
     misc_feature    6972..7004
                     /gene="LAG3"
                     /note="Ig strand E [structural motif]; Region: Ig strand
                     E"
                     /db_xref="CDD:409353"
     misc_feature    7032..7049
                     /gene="LAG3"
                     /note="Ig strand F [structural motif]; Region: Ig strand
                     F"
                     /db_xref="CDD:409353"
     misc_feature    7122..7388
                     /gene="LAG3"
                     /note="Immunoglobulin like; Region: IG_like; smart00410"
                     /db_xref="CDD:214653"
     misc_feature    7152..7166
                     /gene="LAG3"
                     /note="Ig strand B [structural motif]; Region: Ig strand
                     B"
                     /db_xref="CDD:409353"
     misc_feature    7209..7223
                     /gene="LAG3"
                     /note="Ig strand C [structural motif]; Region: Ig strand
                     C"
                     /db_xref="CDD:409353"
     misc_feature    7326..7343
                     /gene="LAG3"
                     /note="Ig strand F [structural motif]; Region: Ig strand
                     F"
                     /db_xref="CDD:409353"
     misc_feature    7386..7634
                     /gene="LAG3"
                     /note="Immunoglobulin domain; Region: Ig_3; pfam13927"
                     /db_xref="CDD:464046"
ORIGIN      

tggagttcagatatgtgcaagagctctgtgcagcatgaaatgttcaccttctgtagaatgggacctgacacctgcaaacagaaacttcttagcaccagggaaaattatcaatggcaccaaacaaacaaaaaaaatcaagcttaaacccatgttttctgcatgtggcctcaattgcaccacagtgaccagctccaggcagaaccttctaatatttagttggctctccgtcttgggaaaccagacctctcccagccctccttgtgtcacaggaggtcccaccccttcttgggaattttgaagtccatttatagttccatctctttggtcccagcctcctttgagggtaaggaagacttagatcttacaccaagaatgcatgctgtatgtgccagcacagtgagaatgggggtagctccagagccagaggggtctctttgcagtgctaaaggcaagaacacagcaagcagtgattatccataattggaagtgttcaggattttcctgagcctggccctgagcaacccagtctagtttgagagtcactctactgggagcagaggggtgaaatagagaccccagaggtcctttcccacctgaatcttcctgtgatactgtgactaacaaacaagtgggtttatttgattttgtggtgtttttcttagtgaggcagtagaagatatcttaaaaaggatgcaggctgctacctgccatgaggtgccaagtggagaggaaattgaaaaaacagctcagttaccactacattctgaattgcagtctggcacacaatcatgttaatccagcacaaatgcatagtgttgcagagagggccaatcccatcttccctttcatgtctcctgctgcctctcttttgtcaacactgatgagcagtagagaattgatccagctgaaaactaaactataaaggaataaacccattttgatttacaatgagccctttcagtttaaaaatgcaccatctccctccctagcaattttttgttcaaagtaaagtggttggggatcaccaaatcagagactttattctcttcaggactattctggagcactgctgtgcccctccttgctgtgccatcatccacagcaactttcccagtgattatattcttctgcaaatgatttttcatagcatcactgctcctttagttaccctctactttttcatatctagctttcccactaagaaagaaacaacatattctctatttagcctgcagcctccagagctccaatgtaccatgagatatgtgctcctgttctcctgccatgatgcaccatgaaaacacagcatgtggatcagacccactttttcacagtttctggggacacaggcaaatacgcctagagccagacccctctgtgctctgagcaatgctcatcctccagcgtctgaaacatgacaaggtgcctcttctctgttggagaaacccaggttactgcccagagtagaacacagagaggatttgagccccatgagcagaaggcacatccttctgtggcagtttttctctgaagggatactgtactgtcagttgagagcaacagcagcaataaagatatgagcctggaatatgtggattggcctttctctcttttatggcactttcagaggttttgtttgcttgatatttctgccaatgctctgcctgctttctgggctatccctggtgtccagcacttgtatgtcatccagctctgctgtgggcactggagcttccagtccactgggtcccaaggaccctgcagatggtcagactctttctctccaggtaccctgggagaaacacattttgggagtcccactctcagaccaaggttcagctcccatcaaagtactcctcagctcatacctgagttaaggcaatctttcaggaccactcagctgctgccccagcctctcaacaacacgttgggtcagtgcctgactccttcacctcagtgtcaaggtcactgtaactgagagcaaagctggcaagtgtctcccatccctctttgctcttgagaaaacccagtgcagccctgggatatttggaaggctattgcatattttttgattggattagaagcatgaacactgcaatgagaagggagtcgaaatataacctagtttgctgcatggatttttgtatttaatccaccccaccctctgtgttgcaaaacatggaggttgtggcatcaaaaatatgacttaactaggtattggccaaggtactgatagccataaccatctccacaggtagctgtgatgaccaataaggattctgtaagtgtcccatctctccttgaggaagaatctggaggtcttttgaaagagaatagttatacagtcctccacagcgaatgctggccagttacaagataccagatgccaaatatgcccatgaatgctgcagattttcttcagtaattaaatcattgggggttttgttatgttttggggtttttttttttagcagaaatgcagcccacaactttagtcagatccccccaatgttgtttcggactttctaattcaggtttctctgggatatgcagctgagtattgtcacacaaagggtactcaccttctagcactgtaaagaaagaggctgcagatttgtccaaagaccccataaagctatgttttcttaaaggtgctctcatgggattctgggaagcagggcactgctagactctcctcagtgccctatcagagatctgtggtgactcaggcactgcctccctaaaaaggaccctttcaaaaaagcctcacaatcaggcagccaatcactctgcctcctcctagcacttctgcagtggcacattttggttttgcccagatctactgggagatggaaactttctcttttccgatgctcttctcctcactgctttttgggacctgtcatctcagatgaatgggtcccttctccaagaccaccctctgatgtgttgatgtgtggtgtacccagcccctggggagataacatgccacttccaggcatcatgaaacatgtttggtgcccaccctggacttaatttcatatacagaatgcacctctggttggtaccttggtagaaactatcatggccctttgtgtgggaaaagtggtttgcattcctctacctcaagggtgcctattttgatgcattaccccattgtgcatctcacagaaagcctaccaagctgtggacaccagctctttctgcctcagggttctgcagcttgacctctctgcagcaacaaggtgttgacttgggaaccactgcatctgtcccaagtgcccagagaagggcagctccactacttcctctctgcagctgagcttagatttcttttagttccctaagcttcccagtcagcgccagaagtctcgcagttaatcccagtccctgttgcctgtgcaggtgcctgttgggtaccaacctgcccagcagctcttgctcacaccacatccttgccagaccttcccttctgtttccccaggtgtggctgctttttgtttacagttccttgccatgaagttattggttatctcccattagtaaggaacttggttttgcctgctatgtttgctttagcactggacaaacagcaatcaggatgttttacgtgaggtccttctggcaagcactctatctcaggaacgcccagacaagctgataactcagtcttcaagtcatggcatggtttcctagatcagccgaagtctgaaaataaattctagagcacctgagaaagtcagcataaagtggaagattgtgactactttcagatttgatggtgcaaggaccaaaacatgaaagtggaatcattcagagaaaaacacggtattacagaaatctggaaatgcagtggaaaattccttcagcaagactaactcaatgatactgcagatcagtgttttctattcctatttttcttggtgagtgtagtttgcatccataagacatgccaagagagacaagaagagcaatgtattaaggctgtgcacaagatgactgctgcggtgaagtccggaacctggctgaagctactaatgcctaacatggacaaaggagcatttagtgagctgagcttctatgtccctgcccttggctactcctgttgcagcctgcccctcattccccatggctctgccagggtcccacacatccctgtcagcctctctgcccaggggacccaggcgggcggttctgagaagatgtccctgtgctgatctctctctggtctctgttatctctgcctcggggtcccattctgggagatgacgaaaatgctattcgagggagtcagcatttaaaatgggtcgttagagagaaacgtcacagtgtctttgctaaagatagcctggtgctgagtaaaacagtgcctctaaaaccttccttttacaacatgctcactcagcataataacccctcggcctcaaacacccctccccagtgccaggcagctcctgtcattttcctgggctctccatcagtctcttgtgaccacctcttgggaagctgtagcaggatgggactacgtcctctgctttgctgagtcttacaagagataagcatttcctagagcatgaattcctttaaaagtggttttgagggctaaagtggaatagtgccagggtgccaaggctacaagagcagagagagttgagatggagggagaaagcaatgagctcaatgtgcccctcaagtgaagccaggagagggggagcagatgatgctggactgcagcaatgtatgtgtctccccaccacggttccaactcccttctctctctctcaccttcacccacacactcacaccattcttgcactgctgattcaagggaaagaagcggttgatgctttatgcttgaactggtcaccacaaactgtttttcttgaacagtaggaaaaaaacacctcctgacaactgtcgcaagttctcccctatctttgctcctctctttctctctcatgcgatcccatggactgtgttacacaagagggcatgtgggaccattacaaagcagtccctcgggtacatggaggcacatgaggttccacctgtacaccagtcccactcctcaggaggctggaaagccatgtgtgatgaaagagatgagacctgtcactgcaacaggggtctgctgaagcgaggcatagcactggccctcttttatcctccaccttcaccacccagctgaggaaaaccagagagcaagcaaggatccttccacagttgaaaagtggccactatgagtcacctcccttcccccagcctgaggaaaagccccaacacttgggggatgagccaccgaggggcttgggtgtctgacacatgtcacgaagggctgattaagtccgaaagagtcagagcagtgggctgctggaaagtgtgaaccttaacagtgggggttctctgagacaaaatgggtcccaggatgaggcacatggatggaaatgtactgccctatgtaaaggtcagcagcttaaagggagcaaggttgagccccctcggtgcatgagcttgagtgggttttcccagaactgctggaggaggagggtcccttcctcacactcctcgtcgtgccacagtattcagcccctcttttcagttctgattccttcttctggatgctcctctctatctccttggaccacccaggctttgtcccatattggccctggactctagattgttgagtcacatgtgccctacttggagctcaccacagaccatttcctcatgctgcctgtgaactgaccaatgagaaaaagccaagaaattagctcatttggaggattaaagaaggaaagaaaaagaaaatgaaggaaaaaaaaaaaccaagaagaaagaacagcagaaataaagaccaacatgttctcaaaagccctgaaacaattagagggaagctgtaagagacggaaagatcaaaccaaaaaaggtaagagatgaaagaaaaacatgaagggcacttgctgggaagtgtcttctacactttttccactggctatgtagaagcgaaatttgtaagaaaaacaacagcgactcaaagaatttccactaaaagatgcttacagctgtgtctctggtccctccctcctctgctctcacgtgcctcaggcttatactggtttcttggtggtgacgcatcttcttagtgatatgaggaaatttgctgcccacctgcaatataagggcatttagggaaatgctttgatcagagagagagagagagagacggcatgagagcaagcacatcccaatgacccctctttgcttacccaccaacttctagcaccttctttgcccatgcctcatttttactgatctcttcaagctttggaccttgtcaagcacggacccaagtaggaggcagcccctcgcctttcctggatgccaccatgaggctggtgtccctggtgctgttcctcacctttgccctgctggctttcggtgctggtcacatcctagcaggattagcggagggggaaagcagggagcagaaaatgtgggtcagagaggggagttcagctgtgctgccctgccactggagccccagaaaaatgagaaagagcttgaagcagctgcccgacaagacatctgtgcagtggaagaggcatgggggaagtgtccaccaggagtcacatggggtgctggaggtggggtactcgggcctccagaagacggcactgctcatgaagccccgggtgtcactccaggactctgccttacacaacggcaatttctccctgcggattgaccccgtcaggagcgaggacgctgggctgtatgaggcacgggtggaatacaactcggaggtccatagctgccatgtggagctgggggtagttacagtaaccctcagtccacccaatcctgtggaagaaaatgagctgctcttgatgagctgcaactccagctaccgggccagccttgtggagatatgttggttccataacgggcacctgggccccacctccaggaccttctgctctttgtctggggctctctccatcctgcggccagccatgagtgatgcaggctcctggcgctgccagcttcgatactctgataacgagataatttctgccacgtacgacctgcaaattctaggttttgatggcccaaccaaccctgtggtctatgctgcagctggctctgcagcccatctaccatgcagcctgagctaccttcccagctcctttcagatgaacatggtgacagcccactggagccatcttgcaggaggacacttgcaagactgggacatcttccaaaatctgagtaacagaagcttccccctgcatctccctgtggtggggccgggtgatgcagggcaataccgctgtgctgtctctgtgggccacaaaacaatcagcagggaggtgaccttggcagtggttacagtgactccaagcatccaaggaccagtttctgaggggagtcgtttgcagctcatctgcagcctcacacactcccggggacatgaacgtttccagtggaagcaccttggctcagtccccactaagagcaagctggctgtggccaccccccaaaacctggagggcaacagcgcccagatgggacctatcttgaaaatacccaaagtgtcacaaaaggatacgggcacatgggaatgcagtgtgtatggcccagaaggccaactgggaggagtggagtacaagctgcagatcacaagtgcccaggtctccagccctcctgctgtcttcagtgggcaagttacttttgggctcacactcactctcttccttctgcttgctgtctgtgttgtggctctggccctacagaaaagggcacagactcctgccttctcagcactggaagggatgattggagtccctgggccgtggaagttgatgaaggaaaaccagaaagggaagatccaacaaactgagtgctgacaggagcagggacaccagggctagtctgcatgggaggatgaaaatctgtgtgccgtgctgcagagagatgggtgccatgcagacctgtcaggggggtctagggatggcatgaacaatgcagaaggcattgggagctctgtatctgcagaggggctgggagctgcctaccagggcaaggcaagcctcactgctgcagtaaggtggccagcagcacagatgctttggagttattgggagtatttgagccagtagctattgcctgctttagtgccaaatctctgcctactctttgtccctttttcgtggctcctctcacaacctttctctggtggaacaccaggatgcaggagatggctggaatctgtctttcctgcagcctgatggtgttttctgccccccttgctcgctttcttctccctctgcctgcactgccctgatcactgtcctgttgcatattttgagcattttaacttattagaaactcattttagaactgaaaataaatcta

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