LOCUS       XM_044766390            3184 bp    mRNA    linear   MAM 26-OCT-2021
DEFINITION  PREDICTED: Equus asinus nuclear factor kappa B subunit 1 (NFKB1),
            transcript variant X2, mRNA.
ACCESSION   XM_044766390
VERSION     XM_044766390.1
DBLINK      BioProject: PRJNA688408
KEYWORDS    RefSeq.
SOURCE      Equus asinus (ass)
  ORGANISM  Equus asinus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_052179.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Equus asinus Annotation Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3184
                     /organism="Equus asinus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9793"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="blood"
                     /breed="Dezhou"
     gene            1..3184
                     /gene="NFKB1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 55 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:106825951"
     CDS             140..3184
                     /gene="NFKB1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit isoform
                     X2"
                     /protein_id="XP_044622325.1"
                     /db_xref="GeneID:106825951"
                     /translation="

MAEDDPYLGGHEQMFHLESLNHTMFNPELFPQEVSLPTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKHTHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACVRGYNPEILVHPDLRYLQAEGGGDRQLTDREKEVIHQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGGGGGGGGAGSTGPGYGFPHYGFPTYGGITFHPGAAKSNAGMKHGTIDTSCKNDPEGCDASDDREAVNLSGKGTETTARKESGGRADAIAPAPPAGAEEGRSCCQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGLVSDDIINMRNDLYQTPLHLAVITKQEAVVEDLLRAGADLSLLDRFGNSALHLAAKEGHDKILGILLKHKKAALLINHPNADGLNAIHIAMMSNSMPCLRLLVTAGADVNAQERKSGRTALHLAVERDNISLAGCLLLEGEAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEEDGEDEGVVPGTTPLDMAASWQVFDILNGKPYEPEFTSDDLLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIKELVDALRQMGYTEAVEVIQAAFCTSGTAAPSPVTTTSQAPSLPLAPASTRQQIVGSTRPAVGTITSIWSDLVTILLSFLTAPSMSQSTTPSCFKQAPLGSSTAHSPRCLLHAHLLKSQPCLLLTLEGFLIPHLNSELTVSIRSARTPGG"

     misc_feature    260..865
                     /gene="NFKB1"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
                     RHD-n_NFkB1; cd07935"
                     /db_xref="CDD:143651"
     misc_feature    order(302..304,308..313,317..322,329..340,563..565,
                     569..574,863..865)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143651"
     misc_feature    884..1189
                     /gene="NFKB1"
                     /note="IPT domain of the transcription factor NFkappaB and
                     related transcription factors. NFkappaB is considered a
                     central regulator of stress responses, activated by
                     different stressful conditions, including physical stress,
                     oxidative stress, and exposure to...; Region:
                     IPT_NFkappaB; cd01177"
                     /db_xref="CDD:238582"
     misc_feature    order(887..889,893..901,905..913,1031..1039,1076..1078,
                     1112..1114,1169..1171,1178..1180,1184..1186)
                     /gene="NFKB1"
                     /note="ankyrin protein binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238582"
     misc_feature    order(893..898,902..904,941..943,947..949,953..955,
                     1052..1057,1064..1066,1070..1072)
                     /gene="NFKB1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238582"
     misc_feature    order(956..958,962..964,1055..1060)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238582"
     misc_feature    1748..1861
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1787..2254
                     /gene="NFKB1"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     Region: ANKYR; COG0666"
                     /db_xref="CDD:223738"
     misc_feature    order(1871..1873,1883..1888,1895..1903,1907..1912,
                     1922..1924,1931..1933,1958..1960,1964..1966,1970..1972,
                     1982..1987,1994..2002,2006..2011,2021..2023,2030..2032,
                     2066..2068,2072..2074,2078..2080,2090..2095,2102..2110,
                     2114..2119,2129..2131,2138..2140)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1871..1960
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1964..2068
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2072..2164
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2174..2272
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2570..2794
                     /gene="NFKB1"
                     /note="Death domain of the Nuclear Factor-KappaB1
                     precursor protein p105; Region: Death_NFkB1_p105; cd08797"
                     /db_xref="CDD:260063"
ORIGIN      

acaccgcgcccgcccgccccgggcgccggctccggtttccgcggccgctcccctcctgctccgcacgcccaggccccgcgcccgcggagggagccccagcgcagggaggccgcgcgcggacgcgccaccaggctccagaatggcagaagacgatccatatttgggaggtcatgaacaaatgtttcatttggagtctttgaatcatacaatgtttaatccagaattatttccacaagaggtgtcactacccacagatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttatgtgtgtgaaggcccatcccacggtggactgcccggtgcgtctagtgaaaagaacaagaagtcctaccctcaggtcaaaatctgcaactacgtgggacctgcaaaggttattgttcagttggtcacaaatggaaaacacacccacctgcatgcacacagtttagtgggaaaacactgtgaggacgggatctgcacggtgactgctggacccaaggacatggtggtcggttttgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcccgaatgacagaggcctgtgtcaggggctataaccccgaaattttggtgcatcctgatcttcgttatttgcaggcagaaggcggaggagaccggcagctcacggatcgggaaaaggaggtcatccaccaggcagctcttcagcagacgaaggagatggacctcagcgtggtgcgactcatgttcacggcgtttcttccggacagcaccggcagcttcacacggcgcctggaacccgtggtgtcggacgccatctacgacagcaaagcccccaatgcctccaacttgaagattgtcaggatggacaggacagctggatgcgtgactggaggggaagagatttatcttctctgtgacaaggttcagaaagatgacatccagatccgattttatgaagaggaagaaaatggtggaatctgggaaggatttggagatttctcccccacagacgttcatagacaatttgccatcgtcttcaagactccgaagtataaagatgtcaacattacaaaaccagcctccgtgttcgtccagcttcggaggaaatctgacttggaaaccagcgaaccaaaaccttttctctactatcctgaaatcaaagataaagaggaagtacagaggaagcggcagaagctcatgcccaacttctcggatagtttcggcggcggcagtggggccggcgctggaggtggtggcatgtttggcggtggtggtggaggagggggtgctggaagcacaggtccagggtacggctttccgcactatggattccctacgtatggtggcattaccttccaccctggagctgcgaaatccaatgctgggatgaagcatggaaccatagacacctcgtgtaaaaatgatcctgaaggttgtgacgcaagtgatgacagagaggctgtaaatctctctgggaaaggaaccgagaccacagcacgaaaggagtctggcggcagggctgatgccattgctccagcgcccccagcgggagcagaggaagggcgctcctgctgtcaggataacctgtttctagagaaggctatgcagcttgccaagcggcacgccaatgcccttttcgactacgcggtgacaggagatgtgaagatgctactggctgtccagcgccatctcactgcagtgcaggatgagaatggggacagtgtcttacacttagcgatcatccaccttcacgcccagcttgtgagggatctgctagaagtcacgtctggtttggtttctgatgacattatcaacatgagaaatgacctctaccagacgcccttgcatttggcagtgatcaccaagcaggaagctgtggtggaggacttgctgcgggccggggccgacctgagccttctggaccgcttcggtaactctgctttgcacctagctgccaaagaaggacatgataaaattctcggtattttactcaagcacaaaaaggcagcactacttatcaaccaccccaatgcggacggtctgaatgccattcacatagccatgatgagcaacagcatgccgtgtctgcggctgctggtgactgccggggcggacgtcaacgcccaggagcggaagtcggggcgcacggcgctgcacctggctgtggagcgggacaacatctccctggccggctgcctgctcctggagggtgaagcccatgttgacagtaccacctacgatggaactacacccctgcacatagcggccgggagagggtctacccggctggccgctctcctcaaagcagcaggagcagaccccttggtggagaacttcgagcctctctacgacctggatgactcttgggaagaggatggagaggacgaaggagtcgtgcctggaaccacacccctagacatggccgccagctggcaggtatttgacatattaaatgggaaaccctatgagcccgagtttacatcagatgatttactggcacaaggagacatgaaacagctgactgaagatgcaaagttgcagctctacaagttgctagaaatccctgatccagacaaaaactgggccactctggcacagaaattaggtctggggatactaaataatgccttccggctgagtcctgccccgtctaagactcttatggacaactacgaggtctctggggggacgataaaagagctggtggacgccctgagacagatgggctacacagaagcagttgaagtgatccaggcagcattctgcacctcaggaaccgcagcccccagcccagtgacgaccacctcccaggccccctcgctgcctctcgcacctgcctccacaaggcagcaaatagtcggctccactaggcctgctgtcggcacgattaccagtatctggtcagatctcgtcaccatccttctcagcttcttgaccgctcccagcatgtcgcagtcgaccactccctcctgcttcaaacaggcccctcttggctcttccacagcacactcacctcgctgcctccttcacgctcaccttttaaagtcgcagccctgtctcctccttactctcgagggattcctgataccccacctgaactcggaactgaccgtgtccatcagaagcgcccgcactccaggaggttag

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