LOCUS       XM_040756630            2845 bp    mRNA    linear   ROD 14-APR-2021
DEFINITION  PREDICTED: Mesocricetus auratus protein argonaute-1 (LOC101838170),
            transcript variant X3, mRNA.
ACCESSION   XM_040756630
VERSION     XM_040756630.1
DBLINK      BioProject: PRJNA719779
KEYWORDS    RefSeq.
SOURCE      Mesocricetus auratus (golden hamster)
  ORGANISM  Mesocricetus auratus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Cricetidae; Cricetinae; Mesocricetus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024429197.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Mesocricetus auratus Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2845
                     /organism="Mesocricetus auratus"
                     /mol_type="mRNA"
                     /isolate="SY011"
                     /db_xref="taxon:10036"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="liver"
                     /dev_stage="adult"
     gene            1..2845
                     /gene="LOC101838170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 6 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:101838170"
     CDS             192..2549
                     /gene="LOC101838170"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X3"
                     /protein_id="XP_040612564.1"
                     /db_xref="GeneID:101838170"
                     /translation="

MVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    234..458
                     /gene="LOC101838170"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    486..638
                     /gene="LOC101838170"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    639..1001
                     /gene="LOC101838170"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(795..797,840..842,882..884,894..896,948..950,
                     969..971,975..977)
                     /gene="LOC101838170"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1134..2420
                     /gene="LOC101838170"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1554..1556,1566..1568,1602..1613,1620..1622,
                     1644..1646,1653..1655,1665..1667,1677..1679)
                     /gene="LOC101838170"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1758..1760,1764..1766,1974..1976,2388..2390)
                     /gene="LOC101838170"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ggcactgtgggcaaaccaatcaagcttctggccaattactttgaggtggacattcctaagattgacgtttatcattacgaggtggacatcaagccggataagtgtcctcgcagagtcaaccgaagcctgaaacgaaattactcaagcttccacctgccacgtctgtcttccacagggaagtggtggaatacatggtccagcatttcaagcctcagatctttggggatcgcaagcctgtatatgatggaaagaagaacatttacactgtcactgcactgcccattggcaacgagagggttgactttgaggtgacaatccccggggaagggaaagacagaatttttaaggtctccatcaagtggctagccatcgtgagctggcgtatgctacatgaagccctggtcagtggccagatccctgtgcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagctactgccttctacaaagcacagccagtgattgagtttatgtgtgaggtcctggacatcaggaacatagatgaacagcccaagcccctcacagattcccagcgtgttcgctttaccaaggagataaaaggcctgaaggtggaggtgacccactgtggacagatgaagaggaaataccgcgtgtgtaatgttacccgacgccctgctagtcatcagacgtttcccttgcagctagagagtggacagactgtggagtgtaccgtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcctacaagttgggcaagaacagaagcatacctatttgcccctcgaggtctgtaacattgtggctgggcagcggtgcattaagaagttgactgacaaccagacctcaaccatgataaaggctacagctaggtcggccccagacagacaggaggagatcagtcgcctgatgaagaatgccagctacaacttagatccctacatccaggaatttggaatcaaagtgaaggatgacatgacggaggtgaccgggcgagtgctgccggcgcccatcttgcaatatggcggccgggtgagcaggaaccgggccattgctacacccaaccaaggtgtctgggacatgcgtgggaagcaattctacaatggcattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaagcaatgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggtcagccttgtttctgcaaatatgcgcagggagcagatagtgtggagcccatgttccggcatctaaagaatacatattcaggactgcagctcattatcgtcatcctgccagggaagacgcctgtgtatgctgaagtgaaacgtgttggagatacactcttgggaatggcaacacagtgtgtacaggtgaagaatgtggtcaagacctcacctcagactctgtccaatctctgtctcaagatcaatgtcaagcttggtggcattaacaacatcctagtgccacaccagcgctctgctgtttttcaacagccagtgattttcctgggcgcagatgttacacaccccccagccggggatgggaagaagccgtctatcacagcggtggtaggcagtatggatgcacaccccagccgatactgtgctactgtgcgtgtgcaacgcccacggcaggagatcattgaagacttgtcctatatggtgcgtgagctgctcatccagttctacaagtccacccgcttcaagcctacccgcatcatcttctaccgagatggggtccctgagggccagctaccccagatccttcactatgagctgcttgccattcgagatgcctgcatcaaactggaaaaagactaccagcctgggatcacttacattgtggtgcaaaaacgtcatcatacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatccccgctgggaccactgtggacaccaacatcactcacccatttgagtttgacttctatctgtgcagtcatgcaggcatccagggtaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcagatgaactccagatcttgacataccagctgtgccacacttatgtacgatgcacacgttctgtctctatcccagcacctgcctactatgcccgattggtggctttccgggcacgataccacctggtggacaaggagcatgacagtggagagggaagccacatatcggggcagagcaatgggcgagaccctcaggccctggccaaagctgtgcaggttcaccaggatacgctacgcaccatgtacttcgcttgaaggcagaatgctgttacctcactggagagaagaaagctttccaagccctgggagctgtaccacccaaatccagaggaaccaaggaagagggaggtggggtcgggagtataagaggccttgtttctgtctacagaggggatataagggtgggaagagggccagcaagacagactaccagccagaaatctctgatagaaacctcatgtcctctaccctctccccatcttgtcatatccgaccccactggaccaaaatgggcagcactagtgcccaccatacacacagttgtctcatgt

//