LOCUS       XM_040288372            6921 bp    mRNA    linear   ROD 22-MAR-2021
DEFINITION  PREDICTED: Ictidomys tridecemlineatus protein argonaute-1
            (LOC101975448), transcript variant X4, mRNA.
ACCESSION   XM_040288372
VERSION     XM_040288372.1
DBLINK      BioProject: PRJNA714113
KEYWORDS    RefSeq.
SOURCE      Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
  ORGANISM  Ictidomys tridecemlineatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024405058.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Ictidomys tridecemlineatus
                                           Annotation Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6921
                     /organism="Ictidomys tridecemlineatus"
                     /mol_type="mRNA"
                     /isolate="GS200"
                     /db_xref="taxon:43179"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="liver"
                     /collection_date="2010"
                     /collected_by="Sandy Martin, University of Colorado,
                     Anschutz Medical Campus"
     gene            1..6921
                     /gene="LOC101975448"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 47 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:101975448"
     CDS             167..2296
                     /gene="LOC101975448"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X3"
                     /protein_id="XP_040144306.1"
                     /db_xref="GeneID:101975448"
                     /translation="

MPHRVGACARGTSSLPVPARYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    233..385
                     /gene="LOC101975448"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    386..748
                     /gene="LOC101975448"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(542..544,587..589,629..631,641..643,695..697,
                     716..718,722..724)
                     /gene="LOC101975448"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    881..2167
                     /gene="LOC101975448"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1301..1303,1313..1315,1349..1360,1367..1369,
                     1391..1393,1400..1402,1412..1414,1424..1426)
                     /gene="LOC101975448"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1505..1507,1511..1513,1721..1723,2135..2137)
                     /gene="LOC101975448"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

cgaatttttaaggtctccatcaagtggctagccattgtgagctggcgcatgctgcatgaggccctggtcagtggccagatccctgttcccctggagtcggtgcaagccttggatgtggccatgaggcacctggcatccatgaggccagggctcctccgtgcccaggatgcctcacagggtgggggcctgtgcccgagggaccagttctctgcctgtccctgccaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaggcacagccagtgattgagttcatgtgtgaggtgttggacatcaggaacatagacgagcagcccaagcccctcacggactctcagcgtgttcgctttaccaaggaaattaagggcctgaaggtggaagtgacccattgtggacagatgaagaggaaataccgtgtgtgtaatgttacccgccgccctgctagccatcagacgtttcccttgcagctggaaagtggacagactgtagagtgcacagtggcacaatatttcaagcagaaatacaaccttcagctcaagtatccccacctaccttgcctgcaagttggccaagaacaaaagcatacctatctgcccctagaggtctgtaacattgtggctgggcagcgctgcataaagaagctgactgacaaccagacttcaaccatgataaaggctacagctaggtcagccccagacagacaggaggagataagtcgcctgatgaagaatgccagctacaacctagatccctacatccaggaatttggaatcaaagtgaaagatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccgggtgagcaggaaccgggccattgccacacccaatcaaggtgtttgggacatgcgggggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggtcagccttgtttctgcaaatacgcacaaggggctgacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaggtgaaacgagttggagatactcttttgggaatggcaacacagtgtgtgcaggtgaagaacgtagtcaagacatcgcctcagactctatccaacctctgcctcaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgctgtctttcaacagccagtgatattcctaggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtagtaggcagtatggatgcccaccccagccgatactgtgctactgtgcgggtacagcgaccacggcaggagatcattgaagacttgtcctacatggtgcgtgagctgctcatccaattctacaagtccacccgcttcaagccgacgcgcatcatcttctatcgagatggggtcccagaaggccagcttccccagatcctccactatgagctactggccattcgagatgcctgcatcaaactggaaaaggactaccagcctgggatcacttacattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccatccatttgagtttgacttctatctgtgcagccatgcaggcatccagggtaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagcttcagatattgacataccagctgtgccacacttatgtacgatgcacacgttctgtctctatcccagcaccagcctactatgcccgcctagtggctttccgggcacgataccacctggtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaggagctgtgccgcccaaatccagaggaagcaaggagaagggaggtggggtagggaggagtgcaggaggccttgtttctttctgcagagggggtgtaacggtggggaatagggccagcaagacagaccaccagccagaaatctctgatattaacctcatgctccccacccctcacctcatcttgtcacatctggccctgaccccactggaccaagaggggcagcactggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaactaaagactcatgcttgacagcttggtaaggtcggctctgtagccctgcggacaaaagctgataggtttgggtttgctactttagttggaaaagtaaagggcttgagaaagtgggtgggaggagggaaggatttttttttaggagccttaatcaaaaaaggtctagatttgtctaaaaagaaaaatgaaaccagacccagatcaatattttaggatactaaatgttttcatgggttcagaatccagtttgtaggaagatttttaatgctaatagttttggttgctcctccccagctgccacccccacccaccgcccttattcctctccacattttctaccccatcctacgcctccttcctgacagtcatccagccctcctagcaacacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaatggtaatgctgcagaactgcaaccttttgtacctttctttgggggatggggtgggggtgggagaggaggtaggtggggaagaaatatcctgaacacaacaagcctccagccagaatgccagctattttgcatttaaaggaattgatttccacattcattgagctttggaaaagattacaacctcaagatggttaaaatccattgacatttgcactttcagacgtgacaagtctcggagctgctgagatgactggcccttggcctttccacttttgcctcttttttccccatacctgccaccctgccctggtctagagttactttcatagcatttctcactcttggcttcttttttttccccctgatggtcaagtttcttgtgtttcaatatttcttaaatggggtgtcttataacagaagatccttaggtttaaaataagaaaaagaaaactaaatgttatttttataccacaacttgagtctattgccaaaatctggaaatcgctcccatgcctgatgagtttacatcccggaaacattgagccatcagaaggaactgtgtacctgacttgtcttctggcctggctaggtaaagggtggtggtctccccaaggtggagctcgagctctatccttcctctgtgcagaaaatacctttttcttgctgcaggctcccttctctgcactatcctgcactctttcctgcaaatgcatcttcccttcctttggactggactgtcctttgactcatcccagattctagcatgtcctgtggacaggctgggaattttgctgctccctaatgcttctgtttacacaaaggaatttttcctggtttcccactagggcatgtgagtgggtggcatggtttttccttttctttttctttttctttttcttttttttttttttgtcttgagatatggggtttggctctcttgcaagactggaaacgaagggggttcttatgctgaccttgaagcaaggtcccctctttccttgactgttctcccccaccctcacctcgtgtcctgaggagtttcaacttcagtggggaaattcctctttttgaagagcttgggcttgggtatccccctctggttatgaagccatgatacctgagatctagcccaggcttggaggccagctgggagaaggagggtctgaatcctggtctgtggagttagagctacccttttctttccaaggcagcccttgtacagacccagatttgctatgcaaaacaatttatcccaggttctgttctggttggctacattgttcaacaacttcataaaacgtagcaaacattcattatggagaaagcaacaggactgttgagtaactcctcctgtatttttttcctgctggctacagtatggggtgccccatgggcacaagcccagctaaggaacagaatggagggctctgggaggaggcagcttactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcacatacagtctacttcatgttctgtcaccctttagggaaggagctctcctaggacagtgggctctgcaagttctctatttgggtacattttggggctgtgataagggcactattcctggagggtctagtcattcaccagcatttgcaaaagtccatagggaacaggtggcagtcccttcttgcagcagcaagtttgtgctctctccttctctatctctgcctcactctctccagttgtgttttaagctggggcttgaaaggcatatttggtcttttggcattgcacatgcctttgaagaaataaaagcaagagaagcagtttgggcaatgataagaaaattacttcttgcttaatgtaatggaaaaatatgtttgagacttgaaaaatacccttgacaatgttgattattcttgttcgaagggtgttacacgcacagtaagaagtggtgttgcaagcaagccaaagcttggtttaagtagtgcttcttaccaggctccaaggaagcactgagagggccctggttagactcatcctcttagacaggcctctaactccctttgtcccactgttttgcctgccttttcctattctcactttccttggcttcctcttccttttttctgttcactcagcttgcttgctggccagcctgcttgcctgtctgcctatgtgatgatgaattctctgcatggctgcagtgatcccactgttagttgacaaagttaggcttaaccccttttctgcagaagaccaagaacctgctccccacacccagtggtattaaccctgggttggactctcctcaagcttacactagggcaaagcagtaggtctgcccaactggcatgaaatcaggagggtttctgtcagttccatatttatccactccttggatctggtttctctcatattttctggttctgcttccttttctctttacctgagacttccctttgctgaggatattccagggttgagctatttgggtattcagggttggagggttagaagatagatacagaggaagaagggagtgtttggaagagagtggagagagtttggattaaagatgagaaaggaaagcagtgctctttgtccagtccaacacgaccttttggtgtcgaggtgctactgttggcttctggggttaaacctggggctattgttgctgggaacacttagaataaggctaaagagggtacctagaagtttgaaacctccctaaaaagctcctagtccccacctgtgagatagctcctctgtggtgtcctctttggctgagaagcagtgtttttggatagtttttttttctttttttttctttttggtccagaatgatgtgaataggactgcacacatgatgaacagccaagacgactgttttcttaccttgctgatgtggtatctgcaaggctagacctggcatcctgtgtgacaaaaaaggatggaagctccttccttttcagggtagaaaagtcatctcaaactagccaaaaggcagttttggaaacaatgttggggaaagtaatttttatttatttactgggtttgggcagatccaggatgatagctgggaagcctttcttcttcaagtctgatcatggcagggatatgcagggcactcttccctctaggccttctaagcagactggggaggagggaattctctggttttctctttccctccacttactaggacttgcctcctcccttggccgggagcgaggctgggttggtgctctccctttactctactcctgacttagaacctctggctgctgtttgggagcccaagaaagggagtggaaggaatgggctcaaaacaaaacaatgatgtggggaaggcagatttcctactttaaaaaggaaaatgggaaactctccaagaattgtgcaagtaaagacaatgtgtccaaaagcactgagtcccctggtgtagtagcaataaggaaaaatgaaatgactttcctgtacacacagtccaacctgattggtgtgtgatgttgcacttagcagccatgtggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaagtgtccctggagccccacagctgtgtacttgtttgcgtttgtttccctttgggacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtgaaattatcccagcagctgtattgtacagttccttcagaagcaagcaacagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaa

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