LOCUS       XM_039731487           10791 bp    mRNA    linear   VRT 24-FEB-2021
DEFINITION  PREDICTED: Passer montanus argonaute RISC catalytic component 2
            (AGO2), transcript variant X3, mRNA.
ACCESSION   XM_039731487
VERSION     XM_039731487.1
DBLINK      BioProject: PRJNA703052
KEYWORDS    RefSeq.
SOURCE      Passer montanus (Eurasian tree sparrow)
  ORGANISM  Passer montanus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea;
            Passeridae; Passer.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_024373034.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Passer montanus Annotation Release
                                           100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10791
                     /organism="Passer montanus"
                     /mol_type="mRNA"
                     /isolate="IOZ18808"
                     /db_xref="taxon:9160"
                     /chromosome="Unknown"
                     /sex="pooled male and female"
                     /tissue_type="blood"
     gene            1..10791
                     /gene="AGO2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 ESTs, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:120512785"
     CDS             774..3218
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X3"
                     /protein_id="XP_039587421.1"
                     /db_xref="GeneID:120512785"
                     /translation="

MDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKQVELEVTLPGEGKDRIFKVAIKWMSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYTGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA"

     misc_feature    909..1136
                     /gene="AGO2"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    1164..1316
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    1317..1679
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1473..1475,1518..1520,1560..1562,1572..1574,
                     1626..1628,1647..1649,1653..1655)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1812..3089
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2223..2225,2235..2237,2271..2282,2289..2291,
                     2313..2315,2322..2324,2334..2336,2346..2348)
                     /gene="AGO2"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2427..2429,2433..2435,2643..2645,3057..3059)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

ctccccttcccccgacagcgtagccggggctcgggctcgctccctcccccgtgccctcccctggagccgccgccgcctccgccgccgcacacacggagacatgtacccgggagccccctccgccggacccggtgagctttcgcccgggtttctttccctcctccgctgcccccggagcggctttcccggtccgtgtccgtggggagccccgggagctcctcttcccccccggctggggcctggctggagcggcggaggaaggagggtcagggcgccgccgccacctcgggcagggccgcgtgtccggaggcccctctgaggggagggtcgccttccctgccgcgctcccccctccctctgccgagccctgaggccggcgcggctcccgctgcggaccggggtctccatttcctctctcccggctccatcccgggattcccggccggccgcgtgttcctgggcggccgcgccgcgatagttgcgcggggaggtgcgggggaagcgcccgcacgtcgggagcgctgaggggcagcgctgggcgtcctccggctcgtctgtgctgggagcgaatctgggagcaaaggaaaggcggacgtgcaaagaagagttagcaactcctctagggacgtttactatcactttggggaaatacagtgctcacacctcctcccccattgccaccaccaatccagggatatgcctttaaacctcctcctcgaccagattttggcacttctgggagaacaatcaaactgcaggccaacttctttgaaatggacattcctaaaatagatatctaccattatgaattggatataaagccagaaaaatgtcctagaagagttaacagagaaatagtggagcatatggttcagcactttaaaacccagatttttggggatcgcaaaccagtgtttgatggaagaaaaaacctttatacagccatgccacttcccattgggagagataaacaggtggagctggaggtcacgctgccaggagaaggaaaggacagaatatttaaggtggccatcaagtggatgtcctgtgtgagcttgcaggctttgcatgatgctctctctggccgcctgccgagcgtcccgtttgagaccatccaggccctggatgtggtcatgaggcacttgccttccatgaggtatactcctgttgggagatctttctttacagcatcagaagggtgctcaaatcctttgggtggtggcagagaagtttggtttggcttccatcagtcagtcagaccttcattatggaaaatgatgctaaatattgatgtgtctgcaactgcattttacaaagcacagccagttattgagtttgtctgtgaagttctggacttcaaaagtattgaagaacaacaaaaacctctgacagattcccaaagggtaaagtttaccaaagaaataaaaggtctgaaggtggagataacacactgtggacaaatgaaaaggaagtacagagtgtgcaatgtcaccagacgaccagcaagtcaccaaacattcccacttcagcaggagaatggacaaacagttgaatgcactgtagctcagtattttaaggacaggcataaattagttttacgctaccctcaccttccatgtttacaagttggacaggagcagaaacacacataccttcctctggaggtgtgcaacatagtggcaggacaaagatgcataaagaaactcactgacaatcagacttccactatgattcgagccactgccagatcagccccggaccggcaggaagagatcagcaaattgatgcggagcgccagtttcaacacagacccttacgtccgagagtttgggatcatggtcaaggatgagatgacagacgtgactggtagagtccttcagcctccctcaatcctctatggaggcaggaataaagcaattgctacaccagtgcaaggtgtctgggacatgaggaataaacaatttcacactggaattgaaataaaggtttgggcaattgcctgctttgctccccagcgccagtgcactgaagttcatcttaagtccttcacagaacagctgaggaagatttccagggatgctggaatgccaatccaggggcagccctgcttctgtaaatacgcccagggagccgacagcgtggagcccatgttcagacacctcaagaacacttacactgggctgcagcttgtcgtggtcattctgccaggaaaaacaccagtctatgcggaggtgaagcgtgttggtgacacggtgctgggaatggccactcagtgtgtgcagatgaaaaacgtccaaagaacaacaccacaaactctgtccaacctttgcttaaaaataaatgtcaaattaggaggtgtaaataacattctattgccacagggaagacccccagtattccaacagcctgtcatattccttggtgcagatgtaactcacccaccagctggggatgggaaaaagccttccattgctgcagttgtgggcagcatggatgctcatcccaaccgttactgtgccactgtgcgggtgcagcagcaccgccaggaaatcatccaggacttggctgccatggtcagggagctgctgatccagttctacaaatccaccaggttcaaaccaactcgaatcatcttctacagggatggtgtttctgaggggcagttccagcaggtcctccaccatgagctgctggctatcagggaggcttgcattaaactggagaaggattatcagcctggcatcacatttatagtggtgcagaaaaggcaccacaccagactcttctgcacggataaaaacgaacgggttggaaaaagtggaaacattccagctggtaccacagtggacacaaaaatcacccacccctcagagtttgacttctacctgtgtagtcatgctgggattcagggaacaagcagaccctctcactaccacgtgctgtgggatgacaatcgcttctcgtcggacgagctgcagatcctcacctaccagctgtgccacacctacgtgcgctgcacgcgctccgtctccatccctgccccggcctactacgctcacctggtggccttcagagccaggtaccatctggtggataaagaacacgatagtgctgaaggaagccacacttctggccagagcaatggcagagaccaccaagcacttgctaaggcagtccaggtgcaccaggacacgctgcgcacgatgtactttgcttgacacgttctcatgttcagcggctccggacaaggcagagttggattcacaccagaccagctgcacttagaccaacagatgccccaccccagggacagccagcaatgagtgatgcatctttattcctttctttcctatttgcaaggaagccttccgtccagaatttcagacttgatcacaaactgcattcttgtaccaaaccccactgttgtcggaaatgtggtttgccaaaaatctctgagctgcttggtgtaaaacagacccagtttttataattaaatcaagagctgcaatctcagggcttagggaagaaaaacaaaaaaccaaaccaacaacccaacccacaaaactcctcattcaagtttgctgttcattgagttgcttttgataatttggaaagatctagttaatactaaggtttgatgagctaaaatgctgtgaatcagcttttagtacaaaaaagcaaaacgtcttttgagtatttatgaagccttgattattctagatacatttacaaaatttttattttcaaaataagagcgtgacaaaattctggtttctaattgtcttataaagattattctcagattattctctgtgtgtctaaggacaaatgtattttctgaagcttgtcttgaatgttttttattgtgctgcattttaaaatgtttttcgtagactaaagatgaatctaaaaaaaaaaaaagaaaaagagtaaacctgtatctaagctttcaatagctacagttagattggcagaagaaaatgtgccatttaaaaaaatttgtaaagattttttttaaatcatactgacagctaactttaggatttgtcatacaggactgtgacacttactttccaaagtctctaaagaatacgggtctgtggtgatgaatacagtacaatcctttttcactgttgtttgagttaatgtaaatgttatatatgtttcacagtattaatgtgatagactagatgctattatttatttttatttactaaggagtgctcattatacttctgttaacatatcaagaatgctttgaacttagaaagtaaaatccttttcgtggggacattactcttcaaatgcaaaaacaaaaaaaatatgcagtcgatgtggtgagaggagagagatgcagccagtgtctgttgtagcttgggatttgcagaaaggctttttcaatgtgcacacaacacagcaggttttacctctgcagttcagacgcacacaagaccaacatcctacattcattcaagcacaaaacaattgtattttatttatatgttgagtagtggtgaagcaggagctctgctagaggagagtggctcgctggaagttaggcagaagtcagagaatctatgcagtaaagataaaaattaggaaactgaagtttacttagggagggaggtgaagctctcttcattatgcataagatccgtaggaaatgtgagagttttgccattctcttaggagaagcattaactaaaactgataattatgagacagatgcttctgttagtttgcacactggattcacaaaaaccataacacacatgtaaaccattgcactaatgacaatgccacgagcaggtttaggagaaaatggaaaaagcccaggaaagttgtttatgctgacttgatcttgtttgtttttccatgggataactgaaataagatgctgagaggcaggttggaaaaccttcattctcctccactgatggatttttgttttgtcttttcccttttctccgagcagctgctcagtctctttggacacttttacctctggccactgggatgggcaagtagctttaacccatgcagagctctgggccacagagcaggtcagctgcaaccaggtggtgttgggtaaggtagaaaatgcccaacctttgctgcataaagacttttaggtacataattccagtccagatcttcaccttgtagcagtgtgtcagttgtcagtgttctgtaggtgaaatgtaaaacctgttaatgaaataatcatatttgtactattctgattgggtgattaggctgctggctcagagtatcctcttggtcatagttctataaattcagatttctgtaaatttgaagcagatcctaggtagcattgtctgtcttgctgtgtgccagcgaggttgtacctacctcccctcaagctcccctaagctgcagatcctccccgtggtgggtgtgttgcacttctctgtgtttccttcagagctttcctatttcagtgaagatattcatttggcagagttttatataagaattatttttatatgaattcttcttatcaaataggataaagatcatccattttaagacatcatttaacttatttgctgtctgttatgcagagacctcttggatgtgaaattcatccccctctttccatgcagatctgggacagtggaattgtacaggtggtcagatggggtgaggagggcaggatctgtcttgacctcaaatctcatttctgaagcagcctgtgactgcactgcatcctatttaaaatgtttcctttgtgagaaaaggagttttaggcaggccctgaatctgagagtagctgttgtttgtgcatcctcttggaatgagcagaaataatgtagctttccttccctaagtatgaagaacttgggatgtttatgtgcatttcaggacatttttaccttttacagatctttctaagcttctaatactgctaattctttatgccttgtgatttacagaaagactccacaactggtaaagttgtaaagcaggtctgtatttatttggtgattggcaaattaatttctaaccctcatgtttcacgtgtgtctccctccttttctctcccaccagtggtgaattagtgaataatttaaagcatttaagaaaaaaatactaattaggtatatactttgtaaagtatagcatgctagcagtccagcacctctcttcctgggaatatttttaacataaattacatattcaagaatgtctcctgtccaaaaaaaaaacctgccacaaacacataaaatcctagaattattttttattctgcacctcccacatgtctggtgcagaacagcaacatctcaggtcagcacaaagctcaagaagtctcagtctcccccaggctgctggtggagaagtgtcagctgaggtcacagctctgagtctgggccactgtgcaggtcaggtcagcaataaccaaatttgtgccaccctcaggcacttggggcattttccagcctgtgcaaaggactctcattgcacagccccccccaaaaacagcatcagcaagtgtgaaatgctgctcttgggaggtgcaagtactatcaaaatacacaaaatatttaaaagtttgtctttttttccctgatgtgcaaaatctaatgcaatgatgaggtttgcttggtggtggagatttctgctgcagtggctgaacagagtaaccagtccactccatctgttccagcccccaggaaaaaactgagctgatcctcaggagcaaatgtcctgttgagaaatgctggaaggaggtggatttgtctctgcctttatgtggcatttcagacagccctatgcaatttaacacgtgtgtgtgtatgcactgatgtacagagtgaggtcacttgttttgttagagctcctcattttggcttggcttgctttagaatatttgactttgtgaattacaatcaatgatcttccacgttccagaggctttggcacaggaattcccttgtttcttgatctgtcaggtaacaaatacctttgatctccatccaggcccccaggcagcattccctgatagtaaaagaaaaaaggttgtgaaggtttggctttaattctgcctctctcaataactcctgcagcctttgttgtaacagagtcttgttcttgttggatcatttttataacataagacaagaggtttttccacaaggattttcaaattgaaacttctggagaggaggtgtgaggagtttagggttttttttcctgaaaagattgaagtttctaagatgcttctaagtttttctttctgactaaagttgttcatgcaggtgcccaaaggcttttgattaaatagcatactcagtcaaataagcacctctggtggcataaataacccataagggactttttttttttaatatatatttttctcattaactaaacgaatgtaagaagagttctcagtatttttcacacttgagaccagtgtaattaaactcacttgttttccttctaccatagtatctctctttgtgtggctttccccattcctaatgcagggcagtcttttgttttttacttctatattccatttggtcacatgcttcttgatgcacacatgccatctttcttaaggaaaacttcaagtagaaggtaattgcactgattgttgggttttttaaactccctttttactgtaagattttttttttttgcatctgctgtagctgttggaaaatactgtaaatactgctctgtacagcaagtactgaaatgctggggataccattccttgttctattttccagaatactgccatattttccagtgttgaggtaggagctttgctgttaaatgctgttacactttgtgtgcattatggtatcaatccaagaagggcacagttgctgtattacagtggaaatacttcgggtttgtctgaatttataaaacatttcttccttctctctgtgcacatttctcccagagcacagagatgcagtttttcagctctgtgctcattgtctgtgcaaggttcaaatgccagttttggtatcagtttgatgactgatggcattaatgtaatatttggattatcagatgtagctctcccaggtcttccttgcttgtctgattcttgtgttgtagaagcagaatccgtggatgtggcagaatttagtggaatgacagggatttgggatccacttatgatgtcttgctgtctgtccctgcatggtgtgggattgggcagtgcagaggatgttccagtgctctgagctgcccatagatctcccatccatccatcagcaattgcctttttcctcccagaaccctcggggatgggacagagcccaactccagcccccttggctgatgttaggatgcaaaccagcaagttctgtcttctgtttctgagggttaaagactggaaagatgcatttctgagagggtttaatccagattgtatgggaagggggtgctgcgtgtgcttggtgtggcacagaacctgtttagtcccatttagtgtttcagttgctttgtcagagtctttctttgaagtgttaatttgaatgtaattgcttggccaaatcactacaaaagtgggtttctgggaatctttagttacaaagcaggtgcagttcaaggctacctcctgtattccttcatggaagaattaattgaagtgaacctcccactaagcagccaaaatgctcccagagggactggatttgtgctggtctgttccttactgggaagtggcagtgccatactgtgatcctgggtggctgctcagccttccctctgtcttccagaggcatccctgtgtattgagagggtaccagacctgccaagtggcacatctggcacatctgcttctggtcaggatcactccatagcagcagctccctctgtgacctgtcccttcacttgactttctatactgttgttttccaaatgaaaaatgtttctgtactttacctgttggccagaaaatgtcaggttttctctgcaaatgacatgaaggtgcttgaaatatattttgagtctgaggcaaaaaatatgtattggattatttttttaatgtgttttctaggtaaggtgacatgtgactgtaagaatgaaaatactttattccctgctcagaaaatgataaacttaaaatgtggggaaaaaaaccaaaccaaaacaaaaaacaacccaaacatgagtatgttcatcttgggactgtttagtgtcagttctgtgcaaagccttggccaaaactcaaccttgacatcagtgcacgtggactgagggtactttaagtgacctgaaatgaaactgtagaaaactgtgttaatacatcagattttgtttacacttattccagacaagcttcctcatctcagaacaaaccactctgctgacagaaatacctgttggagcacagtgtgctgatgtggtttcatagcagtgttaaagttgatttttatttacaagcaactgggctttctgctgtggattttggcctgtcagagtgactttcctgagattctgtgctccctgtaatttccttcccttaatctctgggtctagactctgatgaagctcatccatggcaggaggattgcttatgtcctgactttctggagcccagattttgcaagagactgaataaaccattataaaccagctcattaataactgaatgtggtaaaatcctgtcaggttggttcagttctcagtcatgatttaacaaagcccccccaaaagtgtgaagtgcagggtaaatggctcctctgtcattggtgggagcagagttttgtgttttccagacaaggcagacccaggatcatcaggaagtttggggagtgaaggagctccatgctgggtgctgctcatgccccagagaagagaaaccctgggtaccccgagccttggggaaatgagagagaaagcaaggggagacatttccttcaaaattgccagtttaagcacttgttaaggtgacagtttaattcttagttttccttctggcctctctcaagtgccccacagaaatcctccaccctgcacccatctgctggccccatcccagaaggggaaggctggcagggagctccccaagtcgatttgtggtgttgggagctctgacttggttggggctggatcaggggcgctgctggatctggagggaggagaggttggcaggagttcattgtgggagttctgcaagtggcagcactacaaacccacagcaccagatgcaggctgtggctgctccttcttcccacctaaatatcccccaaaaaagcaattccttgggatttgtgtatgcactgcctcagcagatccattgtaaacctgcctgaggctgctcttccaccagccaacctccctgaggagccctgggatgcatggcagttctgtatcaaagggaatacagggaatgcagttctgtatcaaagggaataatcctttccacagggttctcaggagtgcacaggctttagttatatttttcccccacattttggatgtgctgaaccatggactttgttatttgttttcctcccttctttaagcacaactaaaccacttgctggaacagctgctctctgctcatcagcagggattgcagatgctgtctgacctgggagcaagcctaggagttgtccccaaaatataaattttaacttttctagtcattttattggggtttttttgagtgtgcttggcaggcatgaatggtgaacaggtcagcaggcaagcttgggagtctctaatcctctggatgctgctgtttgtgtttgctgtgttaggttagattcctgtcaggacaaaaaaaaaaaaaaa

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