LOCUS       XM_037501342            4116 bp    mRNA    linear   MAM 29-MAR-2023
DEFINITION  PREDICTED: Talpa occidentalis protein argonaute-1 (LOC119237221),
            transcript variant X2, mRNA.
ACCESSION   XM_037501342
VERSION     XM_037501342.1
DBLINK      BioProject: PRJNA674757
KEYWORDS    RefSeq.
SOURCE      Talpa occidentalis (Iberian mole)
  ORGANISM  Talpa occidentalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Talpa.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_023605305.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_014898055.3-RS_2023_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/24/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Talpa occidentalis"
                     /mol_type="mRNA"
                     /isolate="TD23"
                     /db_xref="taxon:50954"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="spleen"
                     /dev_stage="adult"
     gene            1..4116
                     /gene="LOC119237221"
                     /note="protein argonaute-1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 17 Proteins"
                     /db_xref="GeneID:119237221"
     CDS             202..2775
                     /gene="LOC119237221"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X2"
                     /protein_id="XP_037357239.1"
                     /db_xref="GeneID:119237221"
                     /translation="

MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    301..693
                     /gene="LOC119237221"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:406799"
     misc_feature    721..873
                     /gene="LOC119237221"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:400854"
     misc_feature    874..1236
                     /gene="LOC119237221"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1030..1032,1075..1077,1117..1119,1129..1131,
                     1183..1185,1204..1206,1210..1212)
                     /gene="LOC119237221"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1369..2646
                     /gene="LOC119237221"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1780..1782,1792..1794,1828..1839,1846..1848,
                     1870..1872,1879..1881,1891..1893,1903..1905)
                     /gene="LOC119237221"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1984..1986,1990..1992,2200..2202,2614..2616)
                     /gene="LOC119237221"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      4116
                     /gene="LOC119237221"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

ggcgctcgcggggggagctgctgcaggctccgcggcggcggctacggaggctgcgggggcggcggcgagcgcggccgggcttgggggggggagccgagcccggcccgggagcccgaggagctagagggagcggggtgcctgggcccctcacgctggacgccgcagtctccgggccgcctgacccccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcgggcgcctacctgcccccactgcagcaggtgttccaagcaccccgtcgacctggcattggcactgtgggaaaaccaatcaagctcctggccaattactttgaggtggacatccctaagattgacgtctaccactacgaagtggatatcaagccggataagtgtcctcgcagagttaacagggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcctgtgtatgatggaaagaagaacatttacactgttacagcactgcccattggaaatgaacgggttgactttgaggtgactattcctggggaagggaaggatcgaatattcaaggtctccatcaagtggctagccatagtgagctggcgcatgctgcatgaggccctggtcagtggccagatccctgttcccctggaatctgtgcaagccttggatgtggctatgagacatctggcatccatgaggtacacccccgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagctactgccttctacaaggcacagccggtgattgagttcatgtgtgaggtactggacatccggaacatagacgagcagcccaaacccctcacggactctcagcgtgtgcgcttcaccaaggagatcaagggcctgaaggtggaagtaacccactgtggacagatgaagaggaaataccgagtgtgtaatgttacccgccgccctgctagccatcagacgtttcccttgcaattggaaagtggacagaccgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaaatatccccacctgccctgcctgcaggttggacaggaacaaaagcatacctacctacccttagaggtctgtaacattgtggcggggcagcgctgcattaagaagctgactgataaccagacttcgaccatgataaaggctactgctagatcggccccagacagacaggaggagatcagccgtctgatgaagaatgccagctacaacctcgatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacagggagagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgctacacccaatcagggtgtctgggacatgcggggcaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctacggaagatttccaaggatgcagggatgcccatccagggtcagccttgcttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattattgtcatcctgccagggaagacaccagtatatgctgaagtgaaacgtgttggagatacactattgggaatggctacacagtgtgtgcaagtgaagaacgtggtcaagacttcacctcagactctgtccaacctctgcctcaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgctgtctttcaacagccagtgatattcctgggagcagatgttacacatcccccagcaggagatgggaaaaaaccttctatcacagcagtggtaggcagtatggatgcccaccccagccgttactgtgctacagtgcgggtacagcgaccacggcaggagatcattgaagacttatcctacatggtgcgtgagctcctcatccagttctataagtcaacccgcttcaagcctacccgcatcatcttctaccgagatggggttcctgaaggtcagctcccccagatcctccactatgagctgctggccattcgtgatgcatgcatcaaactggaaaaggactatcagcctgggatcacatacattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggcaacattccagctgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggacgacaaccgtttcacagcagatgagctccagatcttgacgtaccagttgtgccacacttatgtacgatgtacacgctccgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgataccacctggtggacaaggaacatgacagtggagaggggagccacatatctgggcagagcaatgggcgggacccccaggccctggccaaagctgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagcttttcaagccccaagagctgtgccgcccaaatccagaggaagcagggaggagggaagtggggtaggggggagtgcagaaggccttgtttccttctacagaggggacaaaaaggtggggaacagggccagtaagccagaccaccagccagaaatctctgatatccacctcatgccccccacccctcaccccatcttgtcatatctggccctgaccccactggaccaaaaggggcagcactggtgcccaccatacacacaggtgtttcatgtgactcacagtgctaaagactcacgcctgacagcttggtaaggttggctctgcagccctgtggacaaaagctggtaggtttgagtttgatactttagatgggaaagtgagggacttgagacagtgggtgggagaagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaatgaaacaagacccagatcaatattttaggatactagatgttttaatgggttgagaatccagtttataggaagatttttaatgctaatggttttggttgctcctcccccagctgccaccccctacccttaattcctttctctccaccttttctatcctaccttacacctcccagacagatatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctgctggtgggcaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttcattggggggagggggtggggagggagaggagttaggtagggaataaaaagccctaacccaacaggcctccagacagagctccagctatttgcattcgaaggttttgacttccatattcattgagcttttaaaaagatcacaacctcaagatggttaaaatccattgacatttgcactttcagactcaagtctaggagctgctgagatgactggccccggctttccatgtaggcttccttttctccctatcttcattcctccccagcctcccgggtctggagctactttcaaagcatttctcattcttggcttcttttttccctgatggtcaactctcttatatttcaatatttcttaactgggatatcttataacaaaagatccttatgtctaaaaagtaagaaaagaagaacaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaaattcctcccgtgcccaatgagtttacatcccagaaacattgagccatcagaa

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