LOCUS       XM_036351619            6925 bp    mRNA    linear   MAM 30-SEP-2020
DEFINITION  PREDICTED: Myotis myotis argonaute RISC component 1 (AGO1),
            transcript variant X5, mRNA.
ACCESSION   XM_036351619
VERSION     XM_036351619.1
DBLINK      BioProject: PRJNA665501
KEYWORDS    RefSeq.
SOURCE      Myotis myotis
  ORGANISM  Myotis myotis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera;
            Vespertilionidae; Myotis.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_023416324.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Myotis myotis Annotation Release 100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6925
                     /organism="Myotis myotis"
                     /mol_type="mRNA"
                     /isolate="mMyoMyo1"
                     /db_xref="taxon:51298"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="flight muscle"
                     /dev_stage="adult"
                     /country="France: Limerzel"
                     /lat_lon="47.6333 N 2.3500 W"
                     /collection_date="2015"
                     /collected_by="Emma Teeling, Sebastien Puechmaille"
     gene            1..6925
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 4 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:118676947"
     CDS             162..2291
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X3"
                     /protein_id="XP_036207512.1"
                     /db_xref="GeneID:118676947"
                     /translation="

MPHRVGACARGTSSLPVPARYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    228..380
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    381..743
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(537..539,582..584,624..626,636..638,690..692,
                     711..713,717..719)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    876..2162
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1296..1298,1308..1310,1344..1355,1362..1364,
                     1386..1388,1395..1397,1407..1409,1419..1421)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1500..1502,1506..1508,1716..1718,2130..2132)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

attcaaggtctctatcaagtggctagccattgtgagctggcgcatgctgcatgaggccctggtcagtggccagatccctgttcccctggagtctgtgcaagcccttgatgtggccatgagacatctggcatccatgaggccagggctcctccgtgcccaggatgcctcacagggtgggggcctgtgcccgagggaccagttctctgcctgtccctgccaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaggcacagccggtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagccgctcacggactctcagcgtgtgcgctttaccaaggagatcaagggcctgaaggtagaagtgacccactgtggacagatgaagaggaaataccgtgtgtgtaatgttacacgccgccctgccagccatcagacgtttcccttgcagctggagagtggacaaactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccacctgccctgcttgcaagttggccaggaacaaaagcatacctacctgcccctagaggtctgtaacattgtggctgggcagcgctgcattaagaagctgacggacaatcagacttcaactatgataaaggctacagctaggtcggccccagacagacaggaggagatcagccgcctgatgaagaatgccagctacaacctagatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacaggacgagtgctgccggcgcccatcttgcaatatggcggccgggtgagcaggaaccgggccattgccacacccaatcagggtgtctgggacatgcgagggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaagcagtgtcgagaagaggtgctcaaaaacttcacagaccagctgcggaaaatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacgtactctggactacagctcattattgtcatcctgccagggaagacgccagtgtatgctgaggtgaaacgtgttggagacacacttttgggaatggctacacagtgtgtgcaagtgaagaacgtggtgaagacctcacctcaaactctgtccaacctctgcctgaagatcaatgtcaaacttggtggcataaacaacatcctagtcccacatcagcgctctgcagtctttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccgtctatcacagcagtggtaggcagtatggatgcccaccccagccgttattgtgccactgtgcgggtgcagcgacctcggcaggagatcattgaagacttatcatacatggtgcgtgagctgctgatccagttctacaagtccacccgcttcaagcctactcgtatcatcttctaccgagatggggttcctgaaggccagctccctcagatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttatattgtggtgcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggataccaacatcacgcacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagtcgaccatcccattactatgtcctttgggatgacaaccgtttcacagcagatgagctccagatcttgacataccagctatgccacacttatgtacgatgcacacgctctgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgatatcacctagtggacaaggagcatgacagtggagaggggagccacatatcagggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagttttccaagccccaagagctatgccacccaaatccagaggaatcagggaggaggaaggtggggtagggaggagtgcagaaggccttgtttccttctacaaatgggacaaaagggtggggaacagggccagtaagccagaccaccagccagaaattgctgatattcacctcatacccttcaccccatcttgtcacatctgaccctgaccccactggaccaagacgggcagcaccagtgcccaccatacacacaggtgtctcacgtgactcacagtgctaaagactcatgcctgacagcttgttaaggtcggctcggctctacattcctgtggacaaaagctggtaggtttgggtttgatactttagatgggaaagtgaggggcttgaaaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaaggaaaacgaaaccagacccagatcaatattttaggatacaagatgttttaatgggttaagaatccagtttgtaggaggattttttaatgctaatgattttggttgctcctcccgctgctgccaccccccctttccctattcctttctttccaattttcctaccctaccttacatctccctgacagacatccagccccgaataagacttaaggcactatggcacttagctctgaagtgacacaaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttggggggatggggtagggtgggacaggaggtaaatggggaagaaatactcctaacccaacaagcctccagccagagcgccaactattttgcatttaaagcaattgacttccatattcattgagcttttaaaaatattataacctcaagatggttgaaatccattgacatttgcactttcagacctgacaagtctatggagctgctgagatgactggctatgcctcctttcttccctgtcctaccctgaccctcccacctgcctgggtctggagttacttacatagttttttctcactcttggcttcttttcccccaatggtcaagtctcttatgtttcaatatttttaaattggggtgtcttataacaaacgatccttaggtctaaaataagaaaaaagagcaaaaactaaatgctatttttataccataacttgagtttattgccaaaatcttgatatccttccaatgcccaatgagtttacatcccagaaacattgagccattaaaaagaacaatgtacctgacttgttctttggcctggctaagtaagggtggttgtctccccaatgtggggctcaggcttcatctttccgctgtgcagaaaatacctttttcttgctacaggctccctcctctgcactgccctctgccctgcactcttttctgcaagtgcatcttcctctccctctggattgtcctctgacactttggctcatcccagattccagtgtgtcctgtgaatagtctgggggattttgctgctcccttttgcttctgtttacacaaatgaatttttactggtttcccactagggcatgtgagtgggtggcatgggcttttttttttttttttcctccctgcatagagatggggtttggctggcttgtaaaactggaaaagtagggggttgtagcttggtgcctgctggccttgaggcaaggccccctctttccttgactgttcattttctcctttcccactgcttgggatgagaacgtgcagctttggtgtggaaattcctttttttaaggagcttgggcttgggtttgccccaatctggtgataaagccatgacactttagacctagctcaggcttggaggccagctggaggaaggccagtgtgaatctgggcctgtgcagtgagagctaccatttcccctccccaacagccctaatacagacccagatttcctatgcaaaacagtctctcccaggttccattctggttggctactttgttcaatgacttcacaaaacgtagcacaaacattgattatagaggaaggtatcaggactgttgagtaactcctcctttactttcctactggctatggcattgggtgccccatgggaacccagctgaagaacagaatggagggttctgggaggagttagttcactggacagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatatactgtctacttcatattcagtcacccttagaggaggggagctctctttgaacattgggctctgcatgttctcttcttgggtgcattttggggctaggatcagggcagtattcctggaggttccagtcattcaccagcatttgcaaatatccacggggagctggtggtagccacctactctcggccacaagtttgtgttctttcctttttctctttgcctcactctttccagttgggtttggagctggggcttgaaatgcattttttagccctttggcattgcacataccactcaagaaataaaagcaagagcagcagcttgggcaatggcaagaaaatgactttttgctttgacttttttttttttaaatctttgagacttgaaaaatatccttgactttgaggattattcttgtttgaaaggtagtgcatgcagattgcgaactggtgttggcaacaagctttggctttcttggatttggtttaggtagtgtgactcacttaagctctgatgaagcgtgggatgaccccagcctcatcttttagacaagtctcttgctccctttattccaatctttatcttgctttccctattctctcttcccctggcttccttttctttccttttttttcttttcttttctttttttttctatttagtcagcttgcttgctgatctgctttcctgatgatgaattctctgcatgactataatgacccctctgttagctgacaaggtcaagcttattagctccttggctacagaaaaccaagaatctgttccccaagcccagtgatgtcctctttgggctggactgccctcaagcttacactaggtctgagcagcaggcctgcccaaatggtatgaaatcagaggcttctggcaacttccacacctgtccactccttggacttgatttctctcattgcttttcctagatattattccatttttctctacctggggcttctctattctaaggacttgttaggattgagctacttgggtatccagggttgagggtcaggggatggacatagaggaaaaagagagtggtgggaagagaatggagagaatttggataaaaggtgggaaagtagagcactactcatttatcatttttccagtccagcctgaccgattgagagttgaggtgctgttactggtctttggagataagcccgggctcttgttgctgggtatttaggcttagaataatgctgaacaagaaggtacataaagtcgtaaaacctccctaaaaagctcctggttcccacttagtagatagctcctctttggctaagcaacagtgttcttggagttttccttttcttgtccagaattctgtaaatgagactcagtactcaagatgggcagccaaggaaacacttcttagctggcccctggactatctgcaaggcaggtcgggcagtgttttagaccttgcatcgtgtgtaacaaaagatggaagggagttctttctccttcagggtagaaagtcatctcaaactagccaaaatgcaattttggagactacattggaggaagctgtttttatttatatttattgggcctaggccaatccaggatggtagctgggatgccttcctttttaaagtctgatcgtggcagggatatgcagggcactcttttctgtttggccttctaagcagattggggagaagggatgctctggttttctctttcccccatttattaggacttgccttctccctgagcagggagaggctagattggtgctctcctcttattctactcctactgacttagaacctctggctgctgtgtgggagcccaagaaagggagcggagggaatggttcaaatcaaacaaaaatcagaataagatggggaaagcagatttcctactttaaaaaggaatataaactctccaaggattgtgcaagtaaagacaatatatctaatgcaccatgtcccctggtgtagtagcaataaggaaaaatgaaatgactttcctatgaacacagtccaacctgaatggtgtgtgatgttggcacttagcagccatctggtgggcatgtgtgactactctgggttccactttagtttctgaacttttattcttctcaagtccagcatggatagggaaatgtccctggagccccacagctgtgtacttgtttgcatttgtttccctttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtctattgtaaaattatcccagcagctgtaatgtacagttccttctaaaccaagcaacagcagcagcacaattctgtgttttataaaaacaacagtggcttctgtt

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