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2024-03-28 18:50:19, GGRNA.v2 : RefSeq release 222 (Jan, 2024)

LOCUS       XM_033045227            3634 bp    mRNA    linear   VRT 02-APR-2021
DEFINITION  PREDICTED: Amblyraja radiata protein argonaute-3 (LOC116988484),
            transcript variant X4, mRNA.
ACCESSION   XM_033045227
VERSION     XM_033045227.1
DBLINK      BioProject: PRJNA610638
KEYWORDS    RefSeq.
SOURCE      Amblyraja radiata (thorny skate)
  ORGANISM  Amblyraja radiata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
            Elasmobranchii; Batoidea; Rajiformes; Rajidae; Amblyraja.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045982.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Updated annotation
            Annotation Name             :: Amblyraja radiata Updated Annotation
                                           Release 100.20210331
            Annotation Version          :: 100.20210331
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; propagated
                                           RefSeq model
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3634
                     /organism="Amblyraja radiata"
                     /mol_type="mRNA"
                     /isolate="CabotCenter1"
                     /db_xref="taxon:386614"
                     /chromosome="27"
                     /sex="male"
                     /tissue_type="testis, liver"
                     /country="USA: Gulf of Main"
                     /lat_lon="43.1336 N 68.3266 W"
                     /collection_date="2017-09-18"
                     /collected_by="Jeff Kneebone"
     gene            1..3634
                     /gene="LOC116988484"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 11 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:116988484"
     CDS             108..2555
                     /gene="LOC116988484"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X4"
                     /protein_id="XP_032901118.1"
                     /db_xref="GeneID:116988484"
                     /translation="
MREVVDSMVQHFKVQIFGERRPVYDGKKSLYTADPIPVSTTGVDLEVTLPGEGKDRIFRVSIKFVSRVSWHLLHEVLTGRSMPELLPGLDLDKPLSTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKDKLLTGLKVEVTHCGPMRRKYRVCNVTRRPASHQTFPLQLENGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISKLVKNANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRVEPSHFRLQTNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFAAQRQCREEVLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLVIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYCELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADKNERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFSADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHISGQSNGRDPQALAKAVQIHQDTLRTMYFA"
     misc_feature    138..428
                     /gene="LOC116988484"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    456..608
                     /gene="LOC116988484"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    609..986
                     /gene="LOC116988484"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(780..782,825..827,867..869,879..881,933..935,
                     954..956,960..962)
                     /gene="LOC116988484"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1119..2426
                     /gene="LOC116988484"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1560..1562,1572..1574,1608..1619,1626..1628,
                     1650..1652,1659..1661,1671..1673,1683..1685)
                     /gene="LOC116988484"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1764..1766,1770..1772,1980..1982,2394..2396)
                     /gene="LOC116988484"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
cctcttcacggtgccaaggcgtccaggatgtggcaccatgggaaaaccgattaaactgctggccaactgcttccaagtagatatcccaaagattgacgtctacctctatgagggaagtggttgactctatggttcagcattttaaagttcaaatatttggagaaagaagacctgtctacgatgggaaaaagagtctctatactgctgatcccattccagtcagcaccacgggggtggatttggaggtgacgttaccaggagaagggaaagaccggattttcagggtctcaataaaatttgtttcaagagtgagttggcacttgctacatgaagttcttacaggacggagtatgccggagttgctgcccgggttggatctggacaagcctctcagcacaaatcctgtccatgcagttgatgttgttcttcgacatctcccctccatgaagtacacccctgttggccgctctttcttctctgcccccgaagggtatgaccatccattgggtgggggtagagaagtctggtttggttttcatcagtctgtcagaccagccatgtggaaaatgatgctgaacatagatgtttctgccactgctttctataaagcacagccagtaattcagttcatgtgtgaagttctagacatacataatattgatgaacaaccacgacctttgactgattcccatcgcgtcaaattcaccaaagagataaaagacaaacttctcacaggattgaaagttgaagtaactcactgtggacctatgaggagaaagtaccgtgtgtgcaacgtcaccagacgaccagccagtcatcaaacgttccccttacagctggaaaatggacagactgtggaatgcactgtggcgcaatatttcaaacagaaatacaaccttcagttaaaatacccacacctaccctgtctgcaggtgggacaggagcagaaacacacctatctgccactggaggtctgtaacattgtggcgggacagcgttgtatcaagaaactgacggacaatcagacatcaacaatgatcaaagcaacagcacgctcagcacctgatagacaagaggaaataagtaaattggtaaaaaatgcaaactatgacgctgatccttttgtccaggagtttcagtttaaagttcgagatgaaatggctcatgtgactggccgagtacttccagcccccatgctgcagtatggggggagggtggaaccaagtcattttagattacaaactaatcgtacagttgctactccaagtcatggtgtttgggacatgcgggggaaacagtttcatactggggttgaaatcaaaatgtgggcaatagcatgttttgcagcacagagacaatgtagagaagaagtacttaagagtttcactgaccagctacggaaaatatctaaagacgccggaatgccaattcagggccagccatgtttttgtaaatacgcacaaggagctgatagtgtggagccaatgttcaggcatctgaagaatacgtattcaggcctacaacttgttattgttattttacctgggaaaacacctgtctatgctgaagtgaagcgtgtgggagatactctactagggatggccactcagtgtgttcaggtgaagaatgttgttaaaacatctccacagacgttatcaaacctctgcctgaagattaatgtgaaattaggtggaatcaacaacattttggtaccacatcaacgaccatccgtgttccagcaacctgtgatttttctgggagctgatgttacacatccaccagctggagatggcaagaaaccctcaatcgctgctgttgtaggcagtatggatgcccatcctagtcgttactgtgccactgtgcgtgtacagagaccacgacaggagatcattcaagatttagcatctatggttcgagaacttctcatacagttttacaaatcaacgcgttttaagccgacccgaattatattttatcgtgatggagtttctgaagggcagtttcgtcaggttttgtattgcgagcttttggcgattcgagaagcatgcattagcctggagaaagactatcaacctggtattacatatatagtggtgcagaaacggcatcatacacgattattctgtgctgataagaatgaaagggttgggagaagtggaaatattccagcaggaaccacggtagatacagatatcacccacccatatgaatttgatttttatctctgcagccacgctgggatacaggggacaagtcgcccttctcactatcatgttctgtgggatgacaactgcttctctgcggatgagcttcagcttcttacctatcaactgtgtcacacgtatgtgcgttgcacacgctctgtatctatcccagcaccagcgtattatgcacatctagtggcatttagagcaaggtaccatttggtggacaaagagcatgacagtgctgaaggcagtcacatttctggtcagagtaatggacgtgaccctcaggctcttgccaaggctgtgcagattcaccaggacacattgcgcactatgtacttcgcttaagtttgggaaattctctccagaaggaaccgaaaatcacagcctgcaattccagtggggtcagtttacgggcatgtctccagccatactgtaactttcactgtgtggggacaataatttcataaactgacgaaaagagattgtttacctacgaagatcatagcactattatgcaatatgaaaccagccaactgctctgtgtgtgtgtgtgtgtgtgtgtgtgtatgtatgcgcgtgtgggtgtgtgcatgtgcgtgcgtgctccgtcagacctcgtgtctgtctttcctttttttttctccagtatagtttcctttttgcctttacctcagtgtttggcagcacaaacgtcatgcaacatgaaaatgggacaaagaaaaatgtttgacaaaacttggatctcaaaacaagtcactaattagttcaaaggtccaatcatttgcttggagtcttcaacttggaagggtgggtggttggagaaggaggtgaagacttgcttgaaaaaaaatattctagggaataactaccaatgctttataagatccaaaagtccacctccaccaggccacttttcaaattctgcatactcatcaattagtgagttaaatcaacagattattgaactcggctactagttatggttgagcaccataaacagtgcagtggaattttgtatagaagataatatccatgtcttggataacccttaattattgacgatataagatcttttgaaaattccaagaaatggggctatgtttaatgtagaaacttctgctttttgttactgtttacttgctaactcacaacaaaatgtgatgttttctgttttagcatcctatatttattagaaaaaataatgcttaatttaatatggatttacattaaagtatagtagcatcaattctatttagttctggaatgtaaccgtgttgtatactgacagaacattgctaccgttagtgcaataagcggttggtaagaaagcccgtgtcctacgctgttctggagcagcagttgtaccactataatcgtgggagagtggacacctccgcacttcagaaccttatcagttttaataa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]