LOCUS       XM_032207927            5331 bp    mRNA    linear   VRT 30-JAN-2020
DEFINITION  PREDICTED: Aythya fuligula ATPase copper transporting beta (ATP7B),
            mRNA.
ACCESSION   XM_032207927
VERSION     XM_032207927.1
DBLINK      BioProject: PRJNA602521
KEYWORDS    RefSeq.
SOURCE      Aythya fuligula (tufted duck)
  ORGANISM  Aythya fuligula
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes;
            Anatidae; Aythyinae; Aythya.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045559.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Aythya fuligula Annotation Release
                                           100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5331
                     /organism="Aythya fuligula"
                     /mol_type="mRNA"
                     /isolate="bAytFul2"
                     /db_xref="taxon:219594"
                     /chromosome="1"
                     /sex="female"
                     /tissue_type="lung (powdered)"
                     /dev_stage="adult"
                     /country="Sweden"
                     /lat_lon="59.8509 N 17.6300 E"
                     /collection_date="28-Aug-2017"
                     /collected_by="Patrik Ellstrom, Mahmoud Naguib, Josef
                     Jarhult"
     gene            1..5331
                     /gene="ATP7B"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 Proteins, and 99% coverage of
                     the annotated genomic feature by RNAseq alignments"
                     /db_xref="GeneID:116502163"
     CDS             14..4600
                     /gene="ATP7B"
                     /codon_start=1
                     /product="copper-transporting ATPase 2"
                     /protein_id="XP_032063818.1"
                     /db_xref="GeneID:116502163"
                     /translation="

MERKGESKIRRELSCLATLNNKNITLVSIRKRQAARDVPELLIIGEKPRAGSPVEASSNLQKEEKVLQSNSMGMPEVNTIERQALSDTDSPPSCALEPTMKQHFAFDNMGYEESFETLPSPSSQERTVAVRVVGMTCQSCVQSVEGRISKVKGVVSIKVSLEQNNALVKYLQSEISPEQICQEIHDMGFDANVAEKRLTPASVSLPCSREAVIKLRIEGMTCQSCVTSIEGKMKKLHGVAKIKVSLANQEAIIAYQPYIIQPEELKSHISSLGYDCTIKSKSAPLKLSVLDLGRLQSADPKETPASLESDGLEPQAARMGGTATVAVQIEGMHCKSCVRNIEGNISSLPGVQSINVSLERKCAVVRYSPNLITLSALQRAIESLPPGNFKVRLPNDSEANNQPSPPPALPCGLAGEPLDDTTCTAVIRIDGMTCNSCVQSIEGTISQRQGVQHVAVSLAGKTGTIRYDPAVTNGEDLRAAIEDMGFDASVLTDTGTGEHKHRPGASDAAVQPQALESPHQDRASDPLLQGPHLDGPNQPGEAKKCFLQITGMTCASCVSAIERKLQKEDGIVSVLVALMAGKAEIKYKPEFIQPLEIAQLIQNLGFEATVIEDHAETEGNVELLITGMTCASCVHNIESKLMRTNGIFYASVALATCKAHIQFDPEITGPRDIIKIIEEIGFHASVSRRVPNAHNLDHKKEIQQWRKSFLCSLVFGIPVLILMIYMLIPDGGHHGSMVLEQNLIPGLSILNLLFFVLCTFVQFLGGWYFYLQAYKSLKHKTANMDVLIVLATTIAYVYSCVILMVAIIEKAEKSPVTFFDTPPMLFVFIALGRWLEHIAKSKTSEALAKLISLQATEATVVTLGPDHSIIREEQVAVELVQRGDIVKVVPGGKFPVDGKVIEGSSMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLVNATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTVTLLVWITIGFIKFDIIQKYFPNQNKDVTKAELILRFAFQTSITVLSIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITCGVPKVMRVLLLGDTAVLSLKKVLAVVGTAEASSEHPLGVAVTKYCKEELGTQSLGYCTNFQAVPGCGISCKVGGVEAVLGMAEEGLGELDANRSGDSSVPLEDNALIALPESEGPSASHVYSVLIGNREWMRRNGLHIANDVNDAMTDHETKGQTAVLVAIDGALCGMIAIADTVKQEAALAVHTLKNMGIDVVLITGDNRKTAKAIATQVGIKKVFAEVLPSHKVAKVQELQNERRKVAMVGDGVNDSPALARADIGIAIGTGTDVAIEAADVVLIRNNLLDVVASIHLSKRTVRRIRINLILALIYNLLGIPIAAGVFMPVGLVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDTESYEAQAQGRMKPLTPSQISVHIGMDDRRRDSSRPAPWDQISQVSLSSLTSDKLPRRNGFFEEEGDKWSLLMNGRDEEQYI"

     misc_feature    401..586
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(416..424,431..433)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    653..844
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(671..679,686..688)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    992..1165
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1007..1015,1022..1024)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1289..1480
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1307..1315,1322..1324)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1652..1840
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1667..1675,1682..1684)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1877..2068
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1895..1903,1910..1912)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2132..4273
                     /gene="ATP7B"
                     /note="P-type heavy metal-transporting ATPase, similar to
                     human copper-transporting ATPases, ATP7A and ATP7B;
                     Region: P-type_ATPase_Cu-like; cd02094"
                     /db_xref="CDD:319783"
     misc_feature    order(3125..3127,3131..3133,4202..4204)
                     /gene="ATP7B"
                     /note="putative Cu binding site [ion binding]; other site"
                     /db_xref="CDD:319783"
     misc_feature    order(3257..3265,3467..3469,3653..3661,3749..3751,
                     3869..3877,3935..3937,3944..3946,3953..3955,4010..4012,
                     4019..4021)
                     /gene="ATP7B"
                     /note="putative ATP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:319783"
ORIGIN      

gcctgcaaagataatggagaggaaaggggagagtaaaataagaagggaactgtcctgcttagctactttaaacaacaaaaacataaccctggtgtctattcgtaagcggcaggcagctcgtgatgtgcctgaactactgattatcggtgaaaaacccagagcaggatctccggtagaagcaagcagtaacttgcagaaagaagagaaagttttgcaaagtaactccatggggatgccagaagtcaatacaattgaaagacaggctttgtccgacactgattcccctcctagctgtgcactggaacctacaatgaaacagcattttgcttttgacaacatgggctacgaggagagctttgaaaccctgccctcgccatcttcccaggagcgcactgttgcagtcagggttgtggggatgacttgccagtcctgcgtgcagtcagtagaaggacgaatttccaaggtgaagggcgtcgtgagcattaaagtctcccttgaacagaataatgccctagtaaagtacctgcagtcagaaataagcccggaacagatttgccaggaaattcatgacatgggttttgacgctaatgtcgcagaaaagaggttgacaccggcatctgtaagtttaccgtgctcgagggaagcggtaataaagcttcggatagaaggcatgacgtgccagtcctgtgtcaccagcatcgagggaaagatgaagaagctgcatggtgtggcaaaaatcaaggtgtcgctcgctaaccaggaggcaatcattgcttaccagccttacatcattcagcccgaggaactcaagagccatatcagcagcctggggtacgactgcaccattaagagtaaatcagcacctttgaagctcagtgtgcttgatcttgggcgcctgcagagcgcagaccccaaggagacaccggcgagtcttgagagtgatgggttggagccacaggctgccaggatgggtggcacagcgaccgtggctgtgcagatagaaggcatgcactgcaagtcctgtgtcagaaacatcgaaggaaacatatcctctcttccaggcgtgcaaagtattaacgtgtctttggagcgtaaatgtgctgttgtacggtacagcccaaatttaattaccctgtcagctctgcagcgagctattgagtcccttccacctggaaactttaaagtgcgcctccctaatgattcagaagcaaataaccaaccatctccaccgcctgctttgccgtgtggtctcgctggagagccgctggacgacacgacgtgcacggctgttattaggatcgatggtatgacctgcaattcctgtgtgcagtccatagaagggacgatatcgcagagacaaggtgtgcagcacgtagcagtttctttagctggcaagactgggaccatacgttatgatccagctgtcacaaatggagaagacttgagagctgccatagaagacatggggtttgatgcgtctgtgctaacagatactggcacgggagaacacaagcatcggcctggcgccagcgatgctgcggtgcagcctcaagctctggagtctcctcaccaggatcgtgcctcagatcctcttctgcagggtcctcacctcgacgggccaaaccagcccggtgaagccaagaagtgttttttacaaatcactggcatgacctgtgcgtcgtgcgtgtctgccatcgaaaggaaactgcagaaggaagacggaattgtttcagtgttggtagccctgatggcaggtaaagcagagataaaatacaagccagagttcatacagcctcttgaaattgcacagctgatccagaatttgggttttgaggctactgtcatagaagatcatgcagaaacagaaggaaatgtggagcttcttattacagggatgacttgtgcttcgtgtgttcacaacattgaatccaaacttatgagaacaaacggcatattctacgcctcagttgcactggctacttgcaaagctcacatccagtttgatcctgaaattacaggacctcgagacattataaaaataattgaggaaattggctttcatgcttctgtgtctagaagagttccaaatgcacataacttggatcataaaaaagaaatacagcagtggaggaagtctttcttgtgcagcctagtgtttggtatccctgtcttaatcctaatgatttatatgctaatacctgacggcggacaccatgggtctatggtgctggaacagaatctcattcctggattatctatattaaatcttctcttctttgtcctgtgcacttttgttcagtttcttggtggatggtatttttacctacaagcttacaaatccctgaagcacaagacagccaatatggatgtgctcatcgtactggccacgacgattgcttatgtgtattcctgtgtgatcctgatggtggccatcattgaaaaggcagagaaaagtcctgtcactttctttgacactcctccaatgctgtttgtattcattgcccttgggagatggctcgaacacatagcaaagagtaagacctcagaagctcttgctaaacttatatctcttcaagccacggaagccactgtggtgactcttggacctgaccactctatcatcagggaggagcaagtagctgttgaactggttcagaggggtgatattgtaaaagttgttcctggtggaaagttccctgtggatggaaaggtgattgaaggcagttctatggcggatgagtctctcattactggggaagccatgccagtcaccaaaaagcctgggagcacggtgatcgctgggtctataaatgcgcatggctcagttcttgttaacgcaacccatgttggtaacgataccaccctagcacagatcgtgaaattggtggaagaagctcagatgtcaaaggcacctatccagcaactggcagataggtttagtggatattttgttccatttatcatcattatttctacagtgaccttgttagtatggatcacaattggttttataaagtttgatatcattcagaaatattttcctaatcagaacaaagacgttacaaaagctgaactgatactgcggtttgcatttcaaacctcaatcaccgtgctgagcattgcatgcccctgttctttaggcttggctaccccaacagctgtgatggtgggcacaggagttgctgcgcagaacggtattctcatcaaagggggaaagcccctggaaatggcacacaagatcaagaccgtgatgtttgataaaactgggaccatcacctgtggagttcctaaagtgatgagggtgcttctgctgggagacacagctgtgctctctctgaagaaggtcctggcagtggttggcactgcagaagccagcagcgagcatcctttaggagtagcagtgactaaatactgcaaagaggagcttggcacccagagcctgggctactgcaccaacttccaggcggtcccaggctgtggcatcagctgtaaagttggcggcgttgaggctgtcctgggcatggccgaggaggggctgggtgagctggatgctaacaggagcggggacagcagcgttcctctggaagataacgcactgatcgcgctccctgaatcagaaggtccgtcagcttcccacgtgtactcggtgctgattggaaatcgcgagtggatgcggcgaaatggcttgcacatcgcaaatgatgtaaatgatgcaatgacagaccacgaaaccaaaggacagactgccgtattagtggctatagatggtgccctgtgtggaatgattgccatagcagacactgtcaagcaggaggcagcccttgctgtgcacacgctgaaaaacatgggaatagacgtggtgctgataacaggagacaacagaaaaactgcaaaagccattgctactcaggttgggatcaaaaaagtcttcgctgaggttcttccttctcacaaggttgcaaaagtccaggagctccaaaacgagaggcggaaggttgcaatggttggtgacggagtcaatgattcccctgcactagccagggctgacattggaattgcgattggaacgggcaccgacgttgccattgaagcagcagacgttgttctcatccgaaacaacttgctagatgttgttgccagtattcacttatcaaagagaacagtacgaaggatacggataaatctgattcttgccttaatctataatctgcttggaataccaatagcagcaggtgtgttcatgcccgtcggcctcgtgcttcagccttggatgggatcagctgcgatggcagcctcctctgtgtccgtcgtgctgtcctccctgcagctgaaatgttataagaagccagacacagaaagttacgaggcacaagctcaaggccgcatgaagccactgactccttcccaaatcagtgttcacatcgggatggatgataggaggagggattcatccagacccgctccctgggatcagatcagtcaagtctctctctcttctttgacttcagacaagctgcccagacgtaatggcttttttgaggaggaaggggacaagtggtcgctgctcatgaacggcagagatgaagagcagtacatctgaagcaccgtgttcttagtgctgcaggaaacatcccagtgacgagaggagctgagttatgccatcaagatcttcaaggttataagcgaagttgttccttcagctcacaaaacgactgcaactcagtctggtgttgagttgtatgggttgtggattccttcaggccaccagttacgtccagtcactgaaagaatctggggctctgtagtgaactggctcctttgcacacagcaaatactgaaataatgtaaaatttcagagtttaatggagtttctctcttctggactgcttgctgggcaccaaatttcatacttttcactgtttttaactttattctttcaagagtacgtgaagcaaaaatatttttcagagcttccaagtactaatttctctgtccaagtgaaaatatccgtggcataaagagctctgtggttggaagctgtatttttaagcagaatcctaactagtcacactactgtgagagcactttatacttaggattcgtgtgcatcttattggaccaaaaatgcttcagtgtttcactgactgcgtttacagatattcctgtttgggacaaactccttaaagtcactaggaatattccgttcttaatgcaattcctggtccaagttagtgcagcagtttcctgtggataccttgcagaatcctttgacatcctggacaattggacagtcggcttgttcttccctcggactgggtgaagaatttttca

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