LOCUS       XM_029080887            5304 bp    mRNA    linear   MAM 08-MAR-2021
DEFINITION  PREDICTED: Ornithorhynchus anatinus protein argonaute-3
            (LOC100079273), transcript variant X1, mRNA.
ACCESSION   XM_029080887
VERSION     XM_029080887.1
DBLINK      BioProject: PRJNA534073
KEYWORDS    RefSeq.
SOURCE      Ornithorhynchus anatinus (platypus)
  ORGANISM  Ornithorhynchus anatinus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_041743.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Ornithorhynchus anatinus Annotation
                                           Release 105
            Annotation Version          :: 105
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5304
                     /organism="Ornithorhynchus anatinus"
                     /mol_type="mRNA"
                     /isolate="Pmale09"
                     /db_xref="taxon:9258"
                     /chromosome="16"
                     /sex="male"
                     /tissue_type="liver; muscle"
     gene            1..5304
                     /gene="LOC100079273"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 39 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 5 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:100079273"
     CDS             49..2631
                     /gene="LOC100079273"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X1"
                     /protein_id="XP_028936720.1"
                     /db_xref="GeneID:100079273"
                     /translation="

MEIGPAGPVGAQPLLMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYDADPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    265..549
                     /gene="LOC100079273"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    577..729
                     /gene="LOC100079273"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    730..1092
                     /gene="LOC100079273"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(886..888,931..933,973..975,985..987,1039..1041,
                     1060..1062,1066..1068)
                     /gene="LOC100079273"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1225..2502
                     /gene="LOC100079273"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1636..1638,1648..1650,1684..1695,1702..1704,
                     1726..1728,1735..1737,1747..1749,1759..1761)
                     /gene="LOC100079273"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1840..1842,1846..1848,2056..2058,2470..2472)
                     /gene="LOC100079273"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

cgcaccgggccccgggctgtctcacagcagcctcccccagctccatgaatggaaatcggccccgcaggacccgttggggcacagcccctgctcatggtgccaagacgtcctggctatggcaccatgggcaaacccattaaactgctggccaattgcttccaagttgaaatcccaaagattgacgtctacctctatgaggtggatattaaaccagataagtgtcctcggagggtgaacagggaggtggtggattcaatggttcagcattttaaagtaacaatatttggggaccgcagaccagtttatgatgggaaaagaagcctttatacagctaatccactccctgtagcaactactggggtggatttagacgtaacattgccaggagaaggtggaaaagatcgccccttcaaggtgtcaataaaatttgtatctcgagtgagttggcacctgctccatgaagttctgacaggaaggaccttgcccgagcctctggaactagacaagccaatcagcacgaaccctgttcatgccgttgatgtggtgctacgacatcttccctccatgaaatatactcctgtgggtcgctcctttttctccgctccagaaggatatgatcaccctctgggaggaggcagagaggtatggtttggattccatcagtctgttcggcctgccatgtggaaaatgatgcttaatattgatgtttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttctcgacattcataatattgatgaacaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaagggtctaaaggttgaagtgactcattgtggaacaatgagacggaaatatcgtgtttgtaatgtaacaaggagacccgccagtcatcaaaccttccctttacagttagaaaatggccagactgtagagagaacagtagcacagtatttcagagagaagtacaacctccagctgaaatatcctcatcttccctgtctacaagtgggacaggagcagaaacacacctacctgcctctagaagtgtgtaatattgtggcaggtcagcgatgtatcaagaagctaacagacaatcagacatccacgatgatcaaggcaacagcaagatctgccccagatagacaagaggaaattagcagattggtaagaagtgcaaattacgatgcagacccttttgttcaggagtttcagtttaaggttcgggatgaaatggctcatgtgacaggacgtgtacttccagctcccatgctgcagtatggagggcggaatcgaacagtagccaccccaagccatggagtatgggatatgcgaggaaagcaattccacactggagtggaaatcaagatgtgggctattgcgtgttttgccacccagaggcagtgccgagaagaaatactgaagggtttcacggaccagctgcgcaagatctccaaggacgcggggatgcccatccagggccagccgtgcttctgcaaatacgcccagggcgccgacagcgtggagcccatgttccgccatctaaagaacacctattcgggcctccagctcatcattgtcatccttccggggaaaacccccgtctacgcggaggtgaaacgcgtaggagacacactgttggggatggcgactcaatgtgttcaagtgaagaacgtaataaagacgtctcctcaaaccctctcaaacctgtgcctaaagattaatgttaaattagggggaatcaataatatccttgtacctcatcaaagaccgtctgtgttccagcaaccagtgatctttttgggagcagatgtcactcatccacccgctggggatggaaagaagccttctattgctgctgttgtaggtagtatggatgcccatccaagcagatactgtgccacagtaagggtccagagaccccggcaggagatcatccaggatctggcctccatggttcgcgaactcctcatccagttctataaatcgacaaggttcaaacccacacggatcatcttctatcgggatggcgtttccgaagggcagttccggcaggtactgtattatgaactgctggcaattcgggaggcctgcatcagtttggagaaagactaccaacccggaataacttatatagtggtgcagaaacgacatcacactcgactcttttgtgccgaccgaaccgaaagggtgggaaggagcggcaatatcccagctggaaccacagtagatacagacattacgcacccctacgagtttgatttttacctctgtagccatgctggaatacagggtaccagccgaccctcgcactatcacgttttgtgggatgataactgctttacagctgatgaacttcagctgctgacctaccagctctgccacacgtatgtgcgctgcacacgatctgtttctatacccgcaccagcgtattacgctcacctagtagcattcagagcaaggtaccatcttgtggacaaagagcatgacagtgctgaaggaagtcacgtttcaggacagagtaatgggcgagacccacaagctcttgccaaggccgtacagattcaccaagacaccttacgcacgatgtacttcgcttaaaaaaaaaaaaaagcctgaatacacttaaggaagaactgaaaaacaaatccacatacaacgtatgtttccagtggggtcagtttagggggcatgcctccagccatgcagaatccaacactgtgcggaggccaggggcttatcctaaattgatacaaggaagattgtttacttcatcgaggaacacagcactattatgcaatatgaaaccagccaactgcttttttgtgcggtctcctgtaggaagtatcgcagtcattttatttgattatttttatttcttgtagttgaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaaaaaaaagtaaatttaaagatggtttaaaaaaaaaaaacacaacacctataggaacaatcgacgattgttggtaaaaagtgtgcaaaaaagtgcgcggatgagtgtacctgttgtataaaatgtgcatgtatatattccgaaatatacacatgcatactttatgtacctgagtatatatctgtatctaaagagataatagatatatacctgtctgtgtatatatatttttataacccactccattagagaattatctctttattttgctcactctcccgctggcttgcctcttctctccttttctctctctcttaatttccctcactcgttttcttcttccctttgttgcctttttcacttccagatgctatcagtgatattcaaatgttcacatatcccgtgcatttgaatgtgcagcatggctaactacatttcttttgcactccctactccattgggttagccaaccactgttttcgtatctttctacaccgcttggagccctcaactctagaaattgctcttttagaggggataaaagtgatttttatatctatttccatatatgattctgtgagtgtgtatatctgtatacatatatatgtatatgtatatatatatataaatttacatttgccagtgatgcaaagtaggcatataagcagtagcaattgaaactgtcctttctcattagtaaatttactaaagctgctgttttaccgtgtcagaatttgaaacggtttctgtctgacaaatggtatttgggagcttcttgtaagaacacattttttgtgtgcgtttgtgagtttcacatgaaaatctttggaagcattttccgagcaagtatttaaaacattcagaactctagagttgagatctccaaaatggggaggtttttgggtttgggtttttttttgtttttttgtttggttttttttgctagtttacttgctgccgctcaccttaatgtgattttcatatatatttttatatatatgtgtgtgtgtatatacaaatatatatgtctgttttgaagtttagcttccttttcttttatatttattagagtaataataatgctttaatttaataattacagaccatgttggcaacatctttttgtttttagaaaggtaaccatgtttattttaaggactgacaacttgtttttgctatcttttagtgcaataagccgttctaaaggagagctgtgtccgtttagctgaacagaagcagcacctgtcccactggcagtgggagaacgggcacctctatggttttaagagaccaagtcaaaaaaaaaaaaaaaaaaagccttaatttcaaaaggaaagttttgtaatccacaaggggtctagaggatgttcctcttttaaatcaagatggcagcgaaaggtaatggaattgtctgagctgccctgctttgagctttaagattagaaatgaggcgatgcttcgggctaacagaggaccgtgagcatttctggtttcgaagacgctgaacttgtctgaagatgggaaactcttagggcggaattgggtttccaggtgcccgttttcatttagccgaaaggaatggtgacagcgtcttagcgaggcgatcgtttccaaagcgtattttgcttatttattgtgccactttccttttaaaattaaggtgtcggtaacttaaacccttcatttcactttacggaatgcataggaagtgagggctgggatattaaacaagttaaatcactgaaatgtgaaaataaaaagaaaagtaatgaaccttagtacattcattccactttaaaatgaacagagtactttagagctgtcagagcggagcatttattcagtaataacagggagtcaggggagccttgcactttgtaactcatgaaaactgcatttttgactgttttatttgcactggttcaaagtctgctgcagattgtcgatcatgggcattgctgttatcccagtccttatgaatcccacccgttctccacatgaaaaccgatgggtttagccgttttgtctctcttctcatttccacaaaatccactatatttgccaatttactgtattttgagcttaaaatctgagcccgttttgctccaacaggtgtaaaatcctttggccctcttttctgccggagaaccaagaaagtactgtatttgtgcatttgtatattgtaagaaatatatgtagtgctcttcacaacactgtgtcaaagcgcttcacggaacaggtggtgtatatacattatatacctatatatttttctcccattttcccagaaaaatatatacggcaaataaattggtttttattttctctt

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