LOCUS       XM_027606003            8137 bp    mRNA    linear   MAM 06-AUG-2020
DEFINITION  PREDICTED: Zalophus californianus argonaute RISC component 1
            (AGO1), transcript variant X4, mRNA.
ACCESSION   XM_027606003
VERSION     XM_027606003.2
DBLINK      BioProject: PRJNA602522
KEYWORDS    RefSeq.
SOURCE      Zalophus californianus (California sea lion)
  ORGANISM  Zalophus californianus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia;
            Pinnipedia; Otariidae; Zalophus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045598.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Aug 6, 2020 this sequence version replaced XM_027606003.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Zalophus californianus Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8137
                     /organism="Zalophus californianus"
                     /mol_type="mRNA"
                     /isolate="mZalCal1"
                     /db_xref="taxon:9704"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="blood"
                     /geo_loc_name="USA: California"
                     /lat_lon="37.858768 N 122.484010 W"
                     /collection_date="07-Jul-2018"
                     /collected_by="Frances Gulland and Jochen Wolf"
     gene            1..8137
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 16 mRNAs, 8 ESTs, 6 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:113929236"
     CDS             166..2286
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X4"
                     /protein_id="XP_027461804.1"
                     /db_xref="GeneID:113929236"
                     /translation="

MPHRVGACARGTSSLPVPARYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    232..384
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    385..747
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(541..543,586..588,628..630,640..642,694..696,
                     715..717,721..723)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    880..2157
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1291..1293,1303..1305,1339..1350,1357..1359,
                     1381..1383,1390..1392,1402..1404,1414..1416)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1495..1497,1501..1503,1711..1713,2125..2127)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaatcttcaaggtctccatcaagtggctagctattgttagctggcgcatgctgcatgaggccctggtcagtggccagatccctgttcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggccagggctcctccgtgcccaggatgcctcacagggtgggggcctgtgcccgagggaccagttctctgcctgtccctgccaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaggcacagccggtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcccaagcccctcacagactctcagcgtgtgcgtttcaccaaggagatcaaaggcctaaaggtggaagtgacccactgtggacagatgaagaggaaataccgtgtgtgtaatgttacccgccgccctgccagccatcagacgtttcccttgcagctggagagtggacaaactgtggagtgcacagtggcacagtatttcaagcagaaatataaccttcagctcaagtatccccatctgccctgcctgcaagttggccaggaacaaaagcatacctacctgcccttagaggtctgtaacattgtggctgggcagcgctgcattaagaagttgaccgacaaccagacttcgaccatgataaaggctacagctaggtcggccccagacagacaggaggagattagccgcctgatgaagaatgccagctataatctagatccctacatccaggaatttgggatcaaagtgaaggatgacatgacggaggtgacggggcgagtgctgccggcccccatcctgcagtacggcggccggaaccgggccattgccacacctaatcagggtgtctgggacatgcgggggaaacaattctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcacagaccagctgcggaagatttccaaggatgcagggatgcccatccagggccagccttgcttctgcaaatatgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaaacgtgttggagatacactcttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcgcctcagactctgtccaatctctgcctgaagatcaatgtcaaacttggtggcattaacaacatcctggtcccacaccagcgctctgccgtctttcaacagccagtgatattcctgggagcagatgttacacaccccccagcaggggatgggaaaaaaccttctatcacagcagtagtaggcagtatggatgcccaccccagccgttactgtgctactgtgcgggtgcagcgaccccggcaggagatcattgaagacttatcctacatggtgcgtgagctgctcatccagttctacaagtctacccgcttcaagcctacccgcatcatcttctaccgagatggggttcctgaaggccagctcccccagatcctccattatgagctgttggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttacattgtggtgcagaaacgtcatcatacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggacaactgtggacaccaacataacccacccatttgagttcgacttctatctgtgcagccatgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttatgtacgatgcacacgctccgtctctatcccagcacctgcctactatgcccgcctggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaggggagccacatatcggggcagagcaatgggcgggacccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgccgcccaaatccagaggaagcaaggaggaggagggagggtagggaggagttcagaaggccttgtttccttctacaaagggggcaaaagggtggggaacagggccagtaagccagaccaccagccagaagtctctgatgtccacctcatgacccccacccctcaccccatcttgtcacatctggccctgaccccactggaccaagaggggcagcactggtgcccaccatacacacaggtgtctcatgtgacttgcagtgctaaagactcatgcctgacagcttggtaaggtcggctctgcagccccgcggacaaaagctggtaggtttgggtttgataatttagatgggagagtgaggggcttgagaaagtgggtgggaggagggaaggattttttaggagccttaatcagaaaaggtctagatttgtttaagaggaaaaacgaaaccagacccagatcaatattttagaatactagatgttttaatgggttgaaaatccagtttgtaggaagatttttaatgctaatgattttggttgctcctcccccagctgccacccccctttcccttattcctttctctccaccttttctaccccaccttacacctcctccctgacagacatccagcccctagtaagacttaaggcactatggcacttagctctgaagtgacacgaccctgtcttccttccgcctactggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtacctttctttggggggatggggtgggggtgggagaggaggtaggtggggaagaaatacccctaacccaacaagcctccagccagagcgccagctattttgcattcaaaggaattgacttccatattcattgagcttttaaaaagatcacaacctcaagatggttaaagtccattgacatttgcactttcagacatgatgtcttggagctgctgagaggactggcccctggcctctccacttaacgcctcctcttctccctgtccccccagctccccacctgcctgggtctggagttactttcatagcatttctcattcttggcttcttttttcccctgatggtcaagtcgcttatgtttcaatatttcttaactggggtgtcttataacaaatgatctgaagtctaaaatcagaaaaaggagcaaaagctaaatgttatttttataccataacttgagtctattgccaaaatctggaaatccctcccatgcccaataagtttacatcccagaaacattgagccatcagaaggaactatgtaccggacttgttctttggcctggctaggtagagggtggttatctcctcatggtggagctcaggctccatccttcccctgtgcagatactatctttttcttgctataggctccctcctctgcactgccctgcactctttcctgcaagtgcatcttccctttctctggactgtctgacactttggctcatcccagattccagtgtgtcctgtggacaggctgggggattttgctgctccctattgcttctgtttacacaaatgaatttttcccagtttcccactagggcatgtgagtgggtggcatgggcctttgttttgttttgttttttgtctccctagataaagatggggtttggctgtcttgcagaactggaaaagtagggggtttctagcttggtgcctgctggccttgaggcaaggccccctctttccttaactgttcatttttttcctctcccactgcttgggatgaggagttgcagcttcagtgtggatgttcctctttttgaggagcctgggcttgggtttgccccaatctggtgatgaagccatgacactttagacctagctcaggcttggaggccagtctgaatcctggcctgtgtgcttagagctaccatttcccctccccagcagcccttatacagacccagatttgctatgcaaaacagtctatcccaggttttgttctggttggctactttgttcagcgacttcacataacgtagcacaaacattgattatggagaaggcatcaggactgttgagtaactcctcctctacttctttcctactggctatagcatgggatgccccatgggtacagcccagctgaagaacggaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatatactgtctacttcgtgttcagtcaccctttggggaggggagctctcttgggacaatgggctctgcatgttctcttcttgggtgcatttaggggctgggatcagggcactgttcctggagggtccagtcattcaccagcatttgcaaatatccatagggagctggtggtagccacctactctcagcaacaagtttatgttctctcctttttctctctttgcctcactgtctccatttgggttttgagctggggcctgaaatgcattttttagctctttggcattgcacatgccattcaagaaataaaaagcaagagaagcggtttgggcaatggcaagaaaatgacttcttgctctgattttttttttttttaaatctttgagacttgaaaaatacccttgaccttgaggattattctttgaaaggtggtgcatgcagattgagaagtggtattagcaacaagctttggctttcttggatttgatttaagtggtgcttcttacttgtgctctgaggaagtgttggggggaccccagcctcatcctcttggtcaggtctcttgctccctttgttctactctcttgcctctgttttctatttatctctttccctggctccttttccttttttctttcactaagcttgtttgctggcctgcctgcctatgtgatgatgaattctctgcatggctttgataatcccactgttagctagcaaggtcaggcttagctccttggctgcagaagaccaagacttagttccccaagcctggtgatgttctctctgggctggactgccatcagcgttacacaaggacagagcagcagggctgcctaccttgcatgaaatcaggagggcttctgacaacttccacacctgtccactccttggagttggtttttctcattgctttttctagatctggttccatttctctacctgcctcccttttctcaggctgtcctagggttgagctacttggtttccagggttggagggttaggggatggacttgggggaagaagagaatgatgggaagagaatggagagaatttggataaaagatgggaaagagcactgttcattgatcatttttccagtccagtctgacccactgggggttgaggtgctactgttgaactcgagataagcctggggctattgttgatgggaacttaggtttagaataatgttgacaaggaagatacctagaagcatgaaacctcccttaaaagctcctggttcccacctactagatagctccactgcagcctcctcttctgctaagcaacaatgttcttggatggttgtttttttgttttgttttgttttgttttggggggggtcccagaattcaatagatgaggctagcactcaggatgggcagccaaggggacattttgaattcttagctggcccatggggtatctatctgcaaggctggtgggcagtgttttagacccggcatcatgtttaacaaagaagaatggaagttccttccccttcagggtggaaagttatctcaaactagccaaaatgcagttttggaaactacattgggtgaagttattttttatatttactgggcctaggccaatccaggatggtagctgggatgccttccttcttaaagtctgatcatggcagggatatgcagggcactctttcctatttagccttctaagcagattggggagaagggattctgtggttttctctttcccccccttttattaggacttgccttctccctaggcagggagagaggctaggttggtgctctccccttactctattcctactgacttagaacctctggctgctgtttgggagcctaagaatgggagtggagggaatgggctcaaaacaaaacagaataaggtggggaaggcagatttccttctttaaaaaggaaaataggaaaccctccaaggattgtgcaagtaaagacaatgtgtcaaatgcactgagtcccctggtgtagtagcaataaggaaaaatgaaatgactttcctgtgcacacagtccaacctgattggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatccctctcaagtccagcatggatggggaaatgtccctggagccccacagctgtgtacttgtttgcatttgtttccctttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtaaaattatcccagcagctgtaatgtacagttccttctaaagcaagcaacagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaagtgcggtctctctctcttttcccccactcccattaacaaagaaaactgttgggattgattatatctctgatatattttaggttagagtattagattgttataacagcagaactatcacctctataggaaagaaaacaccagagtgttgaaactgcagatttgtgtaaccatacttcacaaggcctccatttattcttcattcaacaaaccatacaaagcactgtgtccagcagtattgttgggggagaaaggaagcacaattcagaaaggaggaaaactgtgtctctctccttaaggagcttaaagtttggtgggggatatgagtggccaaacggttccctagccaaatgatgagggactgaaacaaggctataaagctatagcagtgaagataggaaaggaagatttttgagagacactcagaagatagtactcaatagatgatggaagggagagagaggagtagaggctaataatgctcaggcttctacttgagccataagtatattgggacattcttctaaccaagactgggggagaagggagacgatagaagaaaggtggtgaattttgtgaagatagccttgtatagactgagtgtggaggttcccatgaggcaacaagtttaaggtttccagtaaacacttatattttggtgctcagggaagactacaaaactacagttgtagataatgggattcatactcctatagatggtaggtaaagccgtaggaatgaacaagatggcttagaaaaagagtagagcaagaaaacatagagtccaactccaggaaacacaatttaaaggatgagaggaagctgaacttaagaagactgttaaatcactagtagataccttgtatattttttacttaatgaagtgggagaaaagtcaggagaatggaataggattcaagaagggtgtaattaacaacatgaactgctgccttgaggaggtatttttttctattcagtttaccatcctccaccccatcttctttggcatcttgtaactatatggtcattctccagtatttcttgaaaatgagcattgaaaaaacccaatttaaataaggctaagactaggatttccaagttgttcaccacaaccaccacctccacctccagcttcctcctgtcctcaggagacacttgtaaaagaataaaataaacaaacctaattttgttcctaa

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