LOCUS       XM_023975634            6279 bp    mRNA    linear   VRT 17-DEC-2024
DEFINITION  PREDICTED: Salvelinus sp. IW2-2015 argonaute RISC component 4
            (ago4), transcript variant X3, mRNA.
ACCESSION   XM_023975634
VERSION     XM_023975634.2
DBLINK      BioProject: PRJNA433373
KEYWORDS    RefSeq.
SOURCE      Salvelinus sp. IW2-2015
  ORGANISM  Salvelinus sp. IW2-2015
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Salvelinus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_036869.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 17, 2024 this sequence version replaced XM_023975634.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_002910315.2-RS_2024_12
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 12/13/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6279
                     /organism="Salvelinus sp. IW2-2015"
                     /mol_type="mRNA"
                     /db_xref="taxon:2691554"
                     /linkage_group="LG30"
     gene            1..6279
                     /gene="ago4"
                     /note="argonaute RISC component 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 78
                     long SRA reads, 12 Proteins"
                     /db_xref="GeneID:111955399"
     CDS             170..2827
                     /gene="ago4"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X3"
                     /protein_id="XP_023831402.1"
                     /db_xref="GeneID:111955399"
                     /translation="

MEREPSAMEALGPGPSAPTSLFQPPRRPGMGTVGKPIRLLANHFQVQIPKIDVYHYDIDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDLEVTLPGEGKDQTFKVSLQWVSVVSLQMLLEALSGHNEVPEDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPVIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNDMTEVTGRVLPAPMLQYGGRVSTDTGRDCGRGLSPQNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKLSYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQDLSQEQLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCSDKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPLALAKAVQIHYDTQHTMYFA"

     misc_feature    272..658
                     /gene="ago4"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    689..841
                     /gene="ago4"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    842..1204
                     /gene="ago4"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(998..1000,1043..1045,1085..1087,1097..1099,
                     1151..1153,1172..1174,1178..1180)
                     /gene="ago4"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1343..2698
                     /gene="ago4"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1802..1804,1814..1816,1850..1861,1868..1870,
                     1892..1894,1901..1903,1913..1915,1925..1927)
                     /gene="ago4"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2006..2008,2012..2014,2252..2254,2666..2668)
                     /gene="ago4"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      6279
                     /gene="ago4"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

tcatttccaaatccacaggatatgtgttaaatcactcagaagacaacgcatccacaacacttctggacatctacgcattatattccctttcttaaattagccccccctcagcgtcgcaataccgcccccaatttcagtgtcggtacggagccgccaggccgggacagagatggagagagagccctcggccatggaagcgctcggacccggcccgtcggcccccacctccctcttccagcccccgcggaggcctggcatgggcactgtggggaagcccatccgcctgctggcaaaccacttccaggtgcagattcccaagattgatgtctatcattacgatatcgacatcaagcctgagaaacggcctcggagggtcaaccgggaggtggtggacaccatggttcgccacttcaagatgcagatctttggtgatcgacaaccgggctacgacgggaagaggaacatgtacacggcccacccactacccatcgggagagacagggtggatctggaggtgactctaccgggggaggggaaggaccagaccttcaaggtgtcgctgcagtgggtgtcggtggtgagcctgcagatgctcctggaggccctgtcaggccacaacgaggtccccgaggactctgttcaggccctggacgtcatcacccgccacctgccttccatgaggtacactccagtggggcgctccttcttctcccctccggagggctactaccacccgctgggcggagggagggaggtgtggttcggcttccatcagtcggtccgtcctgccatgtggaacatgatgctcaacatcgatgtctccgccaccgctttctaccgtgcccagcccgtgatcgagttcatgtgcgaggtgctggacatccagaacatcaacgagcagaccaagccactcaccgactcccaacgcgtcaagttcaccaaggagatccgaggtctgaaagtcgaggtcacccactgtggtcagatgaagaggaagtatcgtgtgtgcaatgtcactcgccgccccgccagccaccaaacgttccccttacagctggagaatggccaggccatggagtgtacagtggcccagtacttcaagcagaagtacagcctacagctcaaatacccccacctgccctgcctacaagtggggcaggaacagaagcacacctacctgcccctggaggtttgcaacattgtggccgggcagcgctgcatcaagaagctgacagacaaccagacctccaccatgatcaaagctacagcacgttccgcacccgacaggcaggaagagatcagccgactggtcaaaagcaacagcatggtgggcggtcccgacccctacctgaaggagtttggcattgtggtgcacaacgacatgaccgaggtgacgggccgagtcctcccagcgcccatgctgcagtatgggggccgggtgagtaccgacactgggcgggactgtggcaggggactctctccgcagaataagackgtggccacgcccaaccagggcgtgtgggacatgcgggggaagcagttctacgccgggatagagatcaaggtgtgggccgtggcctgcttcgccccacagaaacagtgcagagaggacctgctcaagagcttcacagaccagctgaggaagatctcgaaggacgcggggatgcccatccagggrcagccgtgtttctgtaaatacgcccagggagcggacagcgtggaacccatgttcaaacacctcaagttgtcctatgtgggactgcagctcatcgtggtcatcctgcccggcaaaacccctgtctacgcggaggtgaagcgggtaggagacacrctcctgggcatggccactcagtgtgtccaggtgaagaacgtggtgaagacgtccccccaaaccctctccaacctctgcctcaagatcaacgccaaactgggtggcatcaacaacgtccttgtgccccatcagagaccctctgtgttccagcaacccgtcatcttcctgggggcggacgtcactcaccctccagccggcgacggcaagaagccctccatcgcggcggtggtgggcagcatggacggccaccccagccgctactgtgccacggtgcgrgtgcagacgtcgcgccaggacctgtcccaggagcagctgtacagccaggaggtcatccaggacctgaccaacatggtgcgcgagctgctcatccagttctacaagtccacgcgcttcaagccaacacgcatcatctactaccgcggcggcgtgtccgagggccaaatgaaacaggtggcgtggccggagctgatagccatcaggaaggcctgtatcagcttggaggaggactaccgaccgggcatcacctacatcgtggttcagaaacgccaccacacccgcctcttctgctcagacaagaccgagagggttggaaagagtggcaacgtccckgccggaaccacggtggacagcacaatcacccacccctccgagtttgacttctacctgtgcagccatgctgggatccagggcaccagccggccctcccactaccacgtcctgtgggacgacaactgcttcacggccgacgagctccagctgctcacctaccagctgtgccacacctacgtccgctgcacccgctcagtctccatccccgcgccagcctactacgcccggctggtggccttccgcgcccgctaccacctggtggacaaagatcacgacagtgcggagggcagccacgtgtcgggccagagtaacggtcgggaccccctggccctggccaaggcagtccagatccactatgatacccagcacaccatgtacttcgcctgagccacgccagcaatgggtgcagttctgtcccttctctctctctctcctctgtctctctctttttttgccagtctctctatctttctctctcttgcgtcttgatctgcaccaaagcggttcgaagccagtgaagtgtgccaatggagtattttccttttcggggaaaaacgacatccggcgttcccgatcgagccgccttctaccagcaatccggcactgagagaccgtggggtttccaatgtacagagaaagcaaatacacgcatacacaagttgagccatttaatttttttcccgttttgaatgtcttttttttgtaacactgagcaatggagcggactgacgccaatcgtcagtggcagctcttctagctaagcaggactcmgtctactttttacctcaaagccctttgggtgaaaatctgtcataaggtcttgggttggtgggggtcatgggggggtatgtatggaaacatgggtggggtggacctttttttgagaatatatttttttccttttatgatcatgtttttcctttctccttttcttcagtctttttacaagcgaggtcacctgggtatccatacccattactctttcttctcccatttagcgaagaataagtgtgtttgtgtatatacgtgtgtgtgtgtctttgtgtgtgtgtgtttcatggcaggccactgaattgtaaagggaaaatcaaggagataactgctgtaaatgcctcagatttgatgtttttatattcacacattacatatatatataaatatttacatctatagaacagattgaactatacaggcttcacagaggccggtgggtgtatgtgtagcagtagcaaccgtggtttagccggtgtggctgactgggcgttgggacctattgaatggttgagagcttcgtgagggtttacggcattgggctaagccgccttagttggtgccccgtgtgaggaaggggatccatcccttaaactggtttgtcacaacggttatgacattgttggggtggagcatgtttttttagcaaggcgctagtcgtctgaatttttcagagcaggaaacacattcacttaacttttggggtttcctttgctaccggccaattcattgcacttaccggggacgctaggtaagcaacagagggcactctctcttaccttttatgcatttatacatacaaatcaaaaagcagaatttgtaagagtttaatataaaactgtttttgtggctaatcttaactattgttcagacatagttggtatatttgatgttgttcttattgttgttgttaatgttcttatctacaattatgataattatcagaccggcagcaaccagatgtgtagttaggagatcagtggctgggtttagagttggacactttgtagcattctggcctccggcgtggggaggcccaaggtggggcctccggcgtggggaggcccaaggtgtatcagtttatgcgcccttctgctcctcagttatgtagtagtttatggtagtagtgaatggtttggctgtgttctccagtagggaatatctgtgttgatctatcactgttactcctgactggtaaaacaggaggctaccgtcagtgctcatctggtgagtattgttggcagcagggggtttcggttcgaatggatgaaaggtgacaatcagggctggcattaggaagaaactgggacggacagtggtaaaaagaggtatgcaataggcaatgagttacatttttagaacttcataatgtgtttctatgatagtttgtgtgtatttgaacaagtatatctatccatgtctaaacttctggtattttttaatgaaataatgttttgaacaccagatatgaacatgaagcataagcactgcccttggatctaacgacacctgaccagtcacgaccgcggttaaagatacaatttaaccacagtcgtggtaatggttgtgcataactcgcagtgaggatggggcggggggggggggacgacggcggcgtgcacgcctcgtcgggggggtcggctcagcgaaaaacccttttgtaataaaccatccgtaaagcagcaggtttgctatgaatgagttttgagcgcctacctgtcgagggcgtgggcgcttgcctatgggaggggagcatggtggcggtccaggcattgcatgcaataagtttgaggggcggggctaaactgttgtggagacgtgcactagtttccccacgtggcaagggtgctgcgttgattcagcctggtgtggtcgtctgcagagtgtgttcctgtgggtgtgaccagactggagcattgtccaggatgtgggtgtggtctcctagcaggggatccaaaggcgttgattactccccagttttgaacatattatcattgcaaagcaatattaacccgaaatccagttttcgaatgaggaaaaagctataattcttcttgtcgacgtggctgttggtctgctctctatcgctgtttgtgtttctgtaacttgttttttgcctgtatcaatcagtgggaatgtgcattcagtggactactctttaggctctgagaataaaaaaataaaaaaaggtaacatttagactttgctcgcctgcatgccagagtattgtctcaaaaaaatctctttagaattatatttattaagagacaggaggaaaatatggtaaatgtttatgaatttagtgagactgttataggctagcaatattgtccactctcaagacgtattttaaagattcctacacaaatgtcagtaaaaaacggaggcacaggccgctagaggctgagcgttcgagcctttgtgtcgtggcccgaagacaaacgaggtactttcttcaaaagtgggcccggtaaagacttgaactctcgcccacgcacaggcctcagtgtagcgtccatttaggcctccacttcctggtttgtgcccctgccacgcctcttggggctgtcctgtctcgtggcgccaccctgctggccacccacacaagcgcacttcctctctgtggggggcctcggcccaaggtgtccacggccacaggaatacctcctttttaacctttttaaagaaccattctttctgtgccccgtttgaaagagagcatgattttattttttaattcctctttgatataatgactacaggtttgttatttgacattgtgtaatttaattttcttctttattctggtgtgtagctctgctgttttttctgctagtggtctgagctgtgtgactgtccaatagcaatagaaaggtaccctgtctgacctgctggggagggggtggggcttcctcaggcccctcccacaaaggcgcctaatcactcgctgtattgctatgtgacatgttgaaaaccttttttattttttttattttattttttagcctgcagggaatatttgtgttattgtgcaaagtaataaattggtattttatgcctatatcata

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