LOCUS       XM_023232173            3752 bp    mRNA    linear   PRI 30-DEC-2019
DEFINITION  PREDICTED: Piliocolobus tephrosceles argonaute RISC catalytic
            component 3 (LOC111555812), transcript variant X3, mRNA.
ACCESSION   XM_023232173
VERSION     XM_023232173.2
DBLINK      BioProject: PRJNA419387
KEYWORDS    RefSeq.
SOURCE      Piliocolobus tephrosceles (Ugandan red Colobus)
  ORGANISM  Piliocolobus tephrosceles
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Colobinae; Piliocolobus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045434.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 25, 2018 this sequence version replaced XM_023232173.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Piliocolobus tephrosceles Annotation
                                           Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3752
                     /organism="Piliocolobus tephrosceles"
                     /mol_type="mRNA"
                     /isolate="RC106"
                     /isolation_source="whole blood"
                     /db_xref="taxon:591936"
                     /chromosome="1"
                     /sex="male"
                     /country="Uganda: Kibale National Park"
                     /lat_lon="0.4862 N 30.3897 E"
                     /collection_date="27-Jul-2014"
     gene            1..3752
                     /gene="LOC111555812"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 37 ESTs, 8 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 28 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:111555812"
     CDS             1153..3033
                     /gene="LOC111555812"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X3"
                     /protein_id="XP_023087941.1"
                     /db_xref="GeneID:111555812"
                     /translation="

MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"

     misc_feature    1153..1494
                     /gene="LOC111555812"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1288..1290,1333..1335,1375..1377,1387..1389,
                     1441..1443,1462..1464,1468..1470)
                     /gene="LOC111555812"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1627..2904
                     /gene="LOC111555812"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2038..2040,2050..2052,2086..2097,2104..2106,
                     2128..2130,2137..2139,2149..2151,2161..2163)
                     /gene="LOC111555812"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2242..2244,2248..2250,2458..2460,2872..2874)
                     /gene="LOC111555812"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gaggctgaggcaggagaactgcttgaacctgggaggtggaggttgcggtgagccaagatcttgccactgcactccagcctgggggacagggcaagattcttgtttcagaaaaaaaaaaagaaacctatggtagcttaatgaaacggaaataaagcctaacatttgaagttggtttattttttccccagctttattcaggtatgattaacaagtaaaagttacatgtatttgaggtatacaatgtgatttttgataatacgtatgcattgtgaaatgattacagcaatcaagctaattaatgtaacaatcacctcataggtatgtgagagacataagaacatgaaatttactctcagcatatttcaagtatacataataattatagtcaccatgcagtacattaggtctccagaacttactcatcttgcaactgaaagtttataccctttgaccagtatctcaccatttgcctcagccctcagccctgggtaactaccattctagcctctgtttctgtgagttgagctttcttagattccacatgtgagatcatacagtatttgtctttctgtgtcttgcttatttcatttaacataatatcctccaggttcatccatgttgtcacagatgacaagacttccttcttttaaaggctaaataatattccattttatgtatataccacattctttttatccatttgtctgtcagtggtcacttaggttgtttccatatcttggctattgcgaataatgctgcagtgaacgtgggagtgcagatatctccttgagatagtgattttattaactttgcatatagtccctgaagtgggattgctagatcatataatagttctatttttaatgttttgaggaacctccatactgttttccgtaaaggctgcaacaagggtttattaattgccaataaaatgctgctgtgaaaaataatgagaaatattgcactgacgatcttacttggttacatttccttttttgcttttgcgtgattttgattttggaagccttgtacgtggtatactgcactgaactaaacagcctttattgaacttgaaatcagctggagaagactggtattgagcactatatttctgccactgccttctacaaagcacaacctgtaattcagttcatgtgtgaagttcttgatattcataatattgatgagcaaccaagacctctgactgattctcatcgggtaaaattcaccaaagagataaaaggtttgaaggttgaagtgactcactgtggaacaatgagacggaaataccgtgtttgtaatgtaacaaggaggcctgccagtcatcaaacttttcctttacagttagaaaatggccaaactgtggagagaacagtagcacagtatttcagagaaaagtatactcttcagctgaagtacccgcaccttccctgcctgcaagtcgggcaggagcagaaacacacctacctgccgctagaagtctgtaatattgtggcagggcaacgatgtatcaagaagctaacagacaatcagacttccactatgatcaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacggatccatttgttcaggagtttcaatttaaagttcgggatgaaatggctcatgtaactggacgtgtacttccagcacctatgctccagtatggaggacggaatcggacagtagcaacaccaagccatggagtatgggatatgcgagggaaacaattccacacaggagttgaaatcaaaatgtgggctatcgcatgttttgccacacagaggcagtgcagagaagaaatattgaagggtttcacagaccagctgcgtaagatttctaaggatgcagggatgcccatccagggccagccatgcttctgcaaatatgcacagggggcagacagcgtagagcccatgttccggcatctcaagaacacatattctggcctacagcttattatcgtcatcctgccagggaagacaccagtgtatgcggaagtgaaacgtgtaggagacacacttttgggtatggccacacaatgtgttcaagtcaagaatgtaataaaaacatctcctcaaactctctcaaacttgtgcctaaagataaatgttaaactcggaggaatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatctttttgggagccgatgtcactcatccacctgctggtgatggaaagaagccttctattgctgctgttgtaggtagtatggatgcccacccaagcagatactgtgccacagtaagagttcagagaccccgacaggagatcatccaggacttggcctccatggtccgggaacttcttattcaattttataagtcaactcggttcaagcctactcgtatcatcttttatcgggatggtgtttcagaggggcagtttaggcaggtattatattatgaactactggcaattcgagaagcctgcatcagtttggagaaagactatcaacctggaataacctacattgtagttcagaagagacaccacactcgattattttgtgctgataggacagaaagggttggaagaagtggcaatatcccagctggaacaacagttgatacagacattacacacccatatgagtttgatttttacctctgtagccatgctggaatacagggtaccagtcgtccttcacactatcatgttttatgggatgataactgcttcactgcagatgaacttcagctgctaacttaccagctctgccatacttacgtacgctgtacacgatctgtttctatacctgcaccagcgtattacgctcacctggtagcatttagagccagatatcaccttgtggacaaagaacatgacagtgctgaaggaagtcacgtttcaggacagagcaatgggcgagatccacaagctcttgccaaggctgtacagattcaccaagataccttacgcacaatgtactttgcttaaatagtccaagtatattctctgagaggaagtactgaaagatgaattgacatacaacgtatgtttccagtggagtcaattgagtaaggacacctccagccatacagaaaccaacactgtgtgggggccaaggtctgatccttatgttaatacaaggaagattgtttacttcatcaaggaacacagcatcattatgcaatatgaaaccagccaactgctttttgtgcggtctcctgtaggaagtatcgcaattgttttgttttcatttcttgtagtctaacccttttaatgcctttacctcaagttgcttggcagcacaactatctttgcaaaaaaaattattgaaaaagtaaatgatggtttaaaaaatatacaccttcatgaataatcaaagtgatttttcaaaattatatgtgcaaaaaattaatgtgcattcatatattcttgtaaaaggtgtctgtgtatttttaaaatatatacatccatacttcatatgcatatatatctggatctggattgataatagatatatatgtgtctgtgtatatattttagaattcattccatttggggaacttcctttcccttttattctactaccactaccgcttttatttctctttttcccttgccttcatcacctatattttttccctaatcctaccagtgacattcaaatattcatgtacctggtttgtttgaatgtaaaatatggcaaacta

//