LOCUS       XM_023205439            3990 bp    mRNA    linear   PRI 30-DEC-2019
DEFINITION  PREDICTED: Piliocolobus tephrosceles NRDE-2, necessary for RNA
            interference, domain containing (NRDE2), transcript variant X1,
            mRNA.
ACCESSION   XM_023205439
VERSION     XM_023205439.1
DBLINK      BioProject: PRJNA419387
KEYWORDS    RefSeq.
SOURCE      Piliocolobus tephrosceles (Ugandan red Colobus)
  ORGANISM  Piliocolobus tephrosceles
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Colobinae; Piliocolobus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_045439.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Piliocolobus tephrosceles Annotation
                                           Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3990
                     /organism="Piliocolobus tephrosceles"
                     /mol_type="mRNA"
                     /isolate="RC106"
                     /isolation_source="whole blood"
                     /db_xref="taxon:591936"
                     /chromosome="6"
                     /sex="male"
                     /geo_loc_name="Uganda: Kibale National Park"
                     /lat_lon="0.4862 N 30.3897 E"
                     /collection_date="27-Jul-2014"
     gene            1..3990
                     /gene="NRDE2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 mRNAs, 149 ESTs, 6 Proteins, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments, including 29 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:111538208"
     CDS             234..3728
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2 isoform X1"
                     /protein_id="XP_023061207.1"
                     /db_xref="GeneID:111538208"
                     /translation="

MALFPAFAGISEAPDSGSSRKELDWLSNPSFCVGSLTSLSQQTEAAPAHVSEGSPLTRSLLKSEPSDESDTNQKLKQISRKKKKEKKKKRKHQHHKKTKRKHGQSSSSRSETDTDSEKDKPSRGVVGSKRESEKPNQGNNAAADTGHRFVWLEDIQAVTGETFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGTSTEKKHSRKQVERYFTKKSVGLMNIDGAAISSKTEPPSSEPISFIPVKDLEDAAPVTTWLNPLGIYDQSTTQWLQGQGPPEQESKQPDTQPDSESAALKAKVEEFNRRVRENPRDTQLWMAFVAFQDEAMRSPGLYAIEEGEQEKRKRSLKLILEKKLAILERAIESNQSSVDLKLAKLKLCTEFWEPSTLVKEWQKLIFLHPNNTALWQKYLLFCQSQFSTFSISKIHSLYGKCLSTLSAVKDGSILSHPALPGTEEAMFALFLQQCHFLRQAGHSEKAVSLFQAMVDFTFFKPDSVKDLPTKGQVEFFEPFWDSGEPRAGEKGARGWKAWMHQQERGGWVVINPDEDDDEPEEDDQEIKDKTLPKWQIWLAAERSRDQRHWQPWRPDKTKKQTEEACEDPERQVLFDDIGQSLIRLSSHNLQFQLVEAFLQFLGVPSGLTPPASCLYLAMDENSIFDNGLYDEKPLTFFNPSFSGASCVGRMDRLGCPRWTRGQNREGEEFIRNVFHLVMPLFSGKEKSQLCFSWLQYEIAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENRNNFCLWKQYAHLEWLLGNTEDARKVFDTALSMAGSRELKDSDLCELSLLYAELEVELSPEVRGAATARAVHILTKLTESSPCGPYTGQVLAVHILKARKAYEHALQDCLGDSCVSDPAPTDSCSRLISLAKCFMLFQYLTTGIDAAVRIYEQVFAKLNSYVFPEGSGEGDSASSQSWTSVLEAITLMHTSLLRFHMKVSVYPLAPLREALSQALKLYPGNQVLWRSYVQIQNKSHSASKTRRFFDTVTRSAKALEPWLFAIEAEKLRKRLVETVQRLDGREIHATIPEIGLTHRIQALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKVLYLDAVEYFPDEMQEILDLMTEKELRVRLPLEELELLLED"

     misc_feature    717..1007
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(717..743,750..755,765..770,774..776,780..824,
                     831..839,843..851,873..881,891..896,900..905,912..932,
                     957..968,978..1007)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1170..2168
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

ccccttggccccgccctaccctgatttgccctgcctcgccctgccccgccgcgtccccgtcccttggccaccctcccctctgggccccgcccctcccgcttcggggtcaagccccagagagcttcgcgaaaaccacatttcccagagtgtaccgcgacggctggggtcctcacactggcgctcgctcgccgacgccatatctgtagagaggaactgcggtacggcctgtggtcatggcgctgttcccggccttcgcggggattagtgaggctcccgatagcgggagctccaggaaagagttagactggctgagcaacccaagcttttgtgttggatccctaacgtccctgagccaacagactgaagcagccccagcccatgtttctgaagggtcaccgctgacacggagtcttctgaaatcagagccttcagatgaaagtgacactaaccaaaagctcaaacaaataagcagaaaaaagaagaaagagaaaaagaagaaaaggaagcatcagcatcataagaaaacaaagaggaagcatgggcagtcgagtagcagcaggtctgagacagacaccgattctgaaaaggacaaaccttccaggggcgtcgtaggcagtaaaagggaatctgagaaaccgaatcaaggaaataatgctgcagctgatactggacatcgctttgtttggcttgaggacattcaggctgtgacgggagaaaccttcagaacagataagaaaccagatcctgcgaactgggagtacaagtctctctaccgaggggatatagcaagatacaagaggaaaggagactcctgccttggcattaaccctaagaagcagtgcatatcttgggaagggacttccacagagaagaagcattcacgcaagcaggttgaacgctattttactaagaagagtgtgggattaatgaacattgatggagctgccatcagcagtaaaactgaacctccctcatctgagcccatctcctttataccagtgaaggacttggaagatgcagctcctgttacaacctggttgaatcctctggggatttatgatcagtcaaccacacagtggctacaaggacagggtcctccagagcaggaatcaaagcagccagacacacagccagacagcgagagtgcggctctcaaggccaaggtggaggagtttaacaggagggtgcgggagaatcctcgggatacgcagctgtggatggcattcgttgcttttcaggacgaggccatgagaagtcctggcctgtatgccatcgaggaaggagagcaggaaaagcgaaagaggtccctgaagctcattctggagaagaagctggccattctggagcgggccattgagagcaaccagagcagtgtggatctgaaactggccaagctgaagctctgcacagagttctgggagccctccactctggtcaaagagtggcagaaactgatatttttgcatcccaataatacagccctttggcagaaataccttttattttgccagagccagtttagtaccttttcgatatcaaaaattcacagtctttatggaaaatgcttgagcactttgtctgctgttaaggacggcagcatcctatctcaccctgcgttgcctggcacggaagaggccatgtttgcactctttcttcagcagtgccactttctgcggcaggccggccactctgagaaggccgtctctttgttccaggccatggtggacttcaccttcttcaaacctgacagcgtgaaagatctgcctaccaaaggacaggtggaattctttgagcccttttgggacagtggagagccccgggctggggagaaaggagcccgaggctggaaggcatggatgcaccagcaggaacgaggtggctgggtggtcatcaacccagatgaggatgacgatgaaccagaagaggatgaccaggaaataaaagataagactctgcccaagtggcagatctggcttgctgctgagcgttcccgagaccagaggcactggcagccctggcgccctgataagaccaagaagcaaactgaggaagcctgtgaggatcccgagagacaggtgttgtttgatgatattgggcagtctttgatcagactttccagccacaatcttcagttccagctggtggaggccttcctgcagttcttgggtgtgccttctggccttactcctccagcctcctgtctttatctggctatggatgagaacagcatctttgataatggactttatgatgaaaagcccttgacttttttcaacccctcgttttccggggctagctgtgttggccgcatggatcggttgggctgtcctcgctggaccaggggtcagaaccgagagggcgaggagttcatccgcaatgtcttccaccttgtcatgcctttgttttcaggcaaagagaagtcccagctctgcttctcctggttacagtatgagattgcaaaggtaatttggtgtctgcacactaaaaacaagaagagattaaagtcacaagggaagaactgcaaaaaactagccaagaatctccttaaggagccagaaaaccgcaacaacttttgcctctggaagcagtatgcacatctagagtggttgcttggcaacacggaggatgccagaaaagtttttgacacagcactcagcatggcaggaagcagagaactgaaagactctgacctctgtgagctcagtctgctctatgctgagctggaggtggagctgtcgccggaagtgagaggcgccgccacggcccgagctgttcacatattaaccaagctgactgagagcagcccctgtgggccctacactggacaggtgttggctgttcacattctgaaagcgcgaaaggcttacgagcacgcgctgcaggactgtttgggtgacagctgtgtctccgatccagctcccaccgattcctgtagccgcctaattagcttggctaaatgcttcatgctcttccagtatttgaccacagggattgatgctgctgtgcggatatacgaacaggtatttgcaaaactgaacagttacgttttcccagaaggctctggcgagggggacagtgccagctcccagagttggaccagtgttcttgaagccatcacactgatgcacacgagcctgctgagattccacatgaaagtgagtgtttacccgctcgcccctctgcgagaggcactctcacaggctttaaagttgtatccgggcaaccaggttctttggaggtcctatgtacagattcagaataagtcccacagtgccagcaagaccaggagattttttgacacagtcaccaggtctgccaaagccttggagccttggttgtttgcaattgaagctgagaaactgaggaagagactggtggaaactgtccagaggttagacggtagagagatccatgccacaattcctgagatcggcttaacacatcggatccaagccctgtttgaaaacgccatgcgcagcgacagtggcagccagtgccccttgctgtggaggatgtatttgaactttctggtttccttaggaaataaagaaagaagcaaaggtgtattctacaaagcacttcagaattgtccttgggcaaaggtgttatacctggacgccgtggagtacttccccgacgagatgcaggagatcctggacctgatgactgagaaggagctccgggtacgcctgccgctggaggagctggagctgctgctggaggattagagggcagcaaggccaagccgcccaccctgcagagctaggaggtgtgagcggagaatatgtgtgttaggagacctcagcttttgagatattctttcttgatagtaataatgtgggctgccagcctcttcacatcttgcacactttttgggtgtgtaaatgacacaaaagctatttacatattatatatgtgaatatgtgtatatttgtatatagccagagagtcatgccaaggggtcattaaaccgatgatgattgaggtgtg

//