LOCUS       XM_021531927            5690 bp    mRNA    linear   VRT 23-SEP-2024
DEFINITION  PREDICTED: Lonchura striata NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), mRNA.
ACCESSION   XM_021531927
VERSION     XM_021531927.2
DBLINK      BioProject: PRJNA391487
KEYWORDS    RefSeq.
SOURCE      Lonchura striata (white-rumped munia)
  ORGANISM  Lonchura striata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
            Passeriformes; Passeroidea; Estrildidae; Estrildinae; Lonchura.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_042571.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Nov 5, 2019 this sequence version replaced XM_021531927.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_005870125.1-RS_2024_09
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 09/20/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5690
                     /organism="Lonchura striata"
                     /mol_type="mRNA"
                     /isolate="Mets1"
                     /db_xref="taxon:40157"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..5690
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 ESTs, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:110471357"
     CDS             323..3826
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_021387602.1"
                     /db_xref="GeneID:110471357"
                     /translation="

MALFPAFAGAGPPGEPPAGSSEGSTRELDWLSNPSFSAEDALLLHQRTAEVANLIPEKSPLIRTSSRSELSEESDTDESLKQTSKKRKKKKKKHHHNKKTKKKTKGDSSSSESEVDTKHIKDKGSGKSSEKETAANLGKKASNVTSSHSIWLDDIQAPSADTFRIDKKPDPANWAYKSLYRGDIARYKRKGESCLGIDAKKQCITWESSASKRKQAQSRPERYFTKNNVKMLNTDGILVCNKSSPSDPPAFIPVSQVETDDSSDTTEVNPLGIYDPSTTVWLQGKGKSADNESVNTQQTIQERGINMNSILMTKVEEYNKKVRENPRDINAWMEFISFQDELMRGPSLYASKGEQELRRKSLKLILEKKLAILERAIESNPSNVDLKLARLKLCTEFWEPPAVIKEWQKLIFLHPNNPEMWKKYLLFCQSQFTTFSVSKINSLYGKCLTTLAAVQDGSMVSHPLLPGTEEAMLAIFIQQCHFLRQAGHSEKAVSLFQALIDFTFFKPDSVKDLPTRGQVEFFEPFWDSGEPRIGEKGARGWKAWMHQQEKGGWVVLKPDDEDEEEIDEDQEIKDKTLPKWHIWLNVEYSREARHWLPWRPDKTKKETEEDCEDPERQVLFDDLGPSLIRLSNPKLQHQLLYSFLQFLGVPCTSKLFPSSLYIAMDENSIFDSVLYDDKPLTSVDFPLSGFNSIGHMDMMSRGRHQIGHYKEGEEFIQNVFHVLFQIFTGKEKSNLAICWLQYEISKVIQCLQAKKKKKLKAQGRKSKKLAKNFLKAPDNRNNLSLWKLYAYLEWLLGNTDDSRKVFDTALCTAGTGGLKSAQLCSLSLLYAQLEVELLESTEGAVMSRAVHILTKLTENGPYVPYSGQVLPVNVLKARKIYEHALQDYLSKTAVSDQDLVNDADQLVNLVGCYALFQYLTVGIDAAVLIYTQASEKLEVSCSQKCENTGENFGIQNFPTALEAVTLLHTNLLRFHMKISVYPLNPLREALTEALKRYPSNQSLWRSYIHIQRKSHSASKARRFFDSVTRSTNSLEPWLFAIQAEQMRKKLAEKVQRADVGEIHCTIPETGLTNRIVALFEHAVQSENGTHCPLLWRMYLNFMASLGKKEKSKGLFYKALQNCPWAKVLYMDAVEYFPEDLQETLDLMTEKELRVRVPMEELDLLLEI"

     misc_feature    806..1084
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(806..832,839..844,854..859,863..865,869..913,
                     920..928,932..940,962..970,980..985,989..994,1001..1021,
                     1040..1051,1061..1084)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1271..2266
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

ccgagtgttccgtcccggcgagcttcatgagggatgggggtggtgggaaactgctctggaaactgcatcccgcctcttcccgcagcagctccctgctccagtcccgcagtgcggcggcggagggtgcacgataagcggggtcccacagaaagccgcgaccccagcgccgagccttcctccccagcgccgagccttccccccccagcgccgagccttccttcccagcgccgagccttcctccccagccgccatcttggcgccgggcggaagaactaccggtcccggcgcgctcggcgtgcggcgccatcttgccgccggagacatggcgctgttccccgccttcgccggggccggcccgcccggggagccccccgcgggcagctccgagggctccacgagagagttagactggcttagtaacccaagcttctctgcagaagatgcactcttactgcaccagcgcactgcagaagttgccaatctcattcctgaaaaatcaccattaataaggacttcttcgagatctgagttgtcagaggagagtgatacagatgagagtctgaaacagacaagtaagaaaaggaaaaagaaaaagaaaaagcatcaccacaataagaagacaaaaaagaaaaccaaaggggattccagtagcagcgaatcagaggtggacactaagcacatcaaggacaaaggaagtggcaaaagtagtgaaaaggaaacagcagcaaatctaggtaagaaagcatcaaatgttaccagcagtcattctatttggctggatgatatccaggcccccagcgcagacaccttccggatagacaagaagccagaccctgcaaactgggcctacaaatccttgtatcgtggggacatagcaaggtataaaaggaaaggagagtcctgtcttggcatagatgcaaagaaacagtgcataacctgggagagttctgcatcaaaaaggaagcaagcacagagtcgacctgagcgctactttacaaagaacaatgtgaagatgctgaacacagatgggattcttgtttgtaataaaagttctccatctgatccacctgcttttataccagtttcccaagtggaaactgatgattcttctgacacaacagaagtaaatcctcttgggatttatgatccgtcaaccacagtgtggctacaaggaaaaggcaagagtgcagacaatgagtctgtaaatacacagcaaacaattcaagagcgtgggataaacatgaactccattctaatgacaaaagtggaagaatataacaagaaagttagagaaaacccaagagatattaatgcttggatggaatttatttcctttcaggatgaattaatgagaggacctagcctttatgccagtaagggagagcaggaattaaggagaaaatcactcaagttaatcttggaaaagaaactggccattttagagagggcaattgaaagcaatccaagtaatgttgatctgaaacttgctaggctgaagctttgcacagaattctgggaaccaccagctgtgatcaaagaatggcagaagctgatttttttacatcccaataatccagagatgtggaagaaataccttctattctgtcaaagtcagttcactaccttttctgtttcaaagatcaacagtctctatggaaaatgtttgacaacactggcagctgtacaggatggcagcatggtatcccatcctctgctgcctggcactgaagaagctatgctggctatatttattcagcaatgccactttctgcgacaggctggccattctgagaaagcagtgtctttgtttcaggctcttattgacttcaccttctttaaacctgacagtgtaaaagatctgccaacaaggggacaggtggaattctttgaacccttttgggatagtggagaaccacgaattggagaaaaaggagcaagaggctggaaagcatggatgcaccaacaagaaaagggtggctgggttgttcttaagcctgatgatgaggatgaggaagaaatagatgaggatcaagaaataaaagataaaactcttcccaagtggcatatttggttgaatgttgaatattcccgtgaggcaaggcactggttaccttggaggccagacaaaactaagaaggaaactgaagaagattgtgaagatccggaaagacaggtgttatttgatgatcttggaccatctttaatccgtctttctaatccaaagcttcaacatcaactattgtactcttttttgcaatttctgggagttccatgtacaagtaaactctttccttccagtctctatattgccatggatgaaaatagcatctttgacagtgtgctttatgatgataaaccactgacttctgttgattttccactttctggattcaacagtattggtcatatggatatgatgtcacgaggcagacatcagataggccactacaaagaaggagaggagttcatacagaatgtcttccatgttctgttccagatatttacaggaaaggaaaaatctaacctggccatttgttggctacagtatgaaatatctaaggtaattcagtgtctccaagctaaaaagaaaaagaagctaaaagcacaggggaggaagagtaaaaagttggccaagaattttcttaaagcacctgacaaccgaaacaacctttctctctggaaactctatgcctacctagagtggctgcttggtaacacagatgattccaggaaggtgtttgacacagctctttgcacagcagggacaggaggattgaaaagtgctcagctctgcagcctcagcctgctgtatgctcagctggaagtggaactgctggaaagtacagaaggagctgtcatgtcacgtgctgttcatatattgaccaaattgactgaaaatggaccatatgtgccctacagtggacaagtgctacctgtgaatgtcttgaaagctcgtaaaatatatgagcatgcactgcaagattatttaagtaaaacagcagtatctgatcaggatctggtcaatgatgctgatcagctggttaacctggttggttgttatgcactgtttcagtatttgactgttgggattgatgctgcagtattaatatatacgcaggcttcagaaaaacttgaagtttcttgttcacagaaatgtgaaaatacaggagagaattttggcattcaaaattttcccactgctcttgaagctgtcacactgctgcatacaaatttactgagattccacatgaaaattagtgtttatcctttgaatcccctgcgagaggcactgacagaggctctgaaacggtatcctagcaaccagtctctttggaggtcatacatccatatccaaaggaagtctcacagtgcaagcaaagcacgaagattttttgatagtgtcacaaggtctactaactctttagagccatggctgtttgcaatccaagcagagcagatgagaaaaaaactcgcagagaaggtccagagggcagatgttggtgaaatacattgtactattcctgaaactggattaacaaatcggattgtagctctgtttgaacatgcagttcagagtgaaaatggtacccactgtccactgctatggagaatgtacttgaactttatggcttcactaggaaaaaaagaaaagagtaaaggattgttttataaagcccttcaaaactgtccttgggcaaaggtactctacatggatgcagtagagtatttccctgaagatctgcaagagacacttgatctaatgactgaaaaagaattgagagtgcgggtgcctatggaagagctggatctactactagagatttaaaagaagactgtagcggagtggaggaagtacagaagctgcttccaaagctaacaattatttccattttcatacaggaactctgttgggacttgggtactatgtacttgatattttttgttgttaagtattttatataaattcctatcaaaatggagttctactacctgcaagtattctggaatcaaggactgcattttgcccacagtaatggatccatttctccgaagtattgctggctcccacagaaggataccctctttaaatagcctcctgttggaagttgcctgcattttttattctgttgtttgaaattacattccctagggttcagtagaggttcagtacatgccgactatggcttggtgagcagcataaaaaataaacatctgccaaatggatgctccactgtcctccagttggcagacttcagtaatttccttcagcatggtatggctgtacatatacaactgccaagtcaaagagccgttacatctgtacatatactgtgagtaaaagctaaattattgtttgagcaggcacctattttggtatgttttgacagatgaccatttaaatgtaaatctttctgaaaaatgtacctgaatatttgagaattcaaaagtaatttgttttttatgtattaatttaatagaactgagtgtattaaaaatgaaaacacatccataatgtatctctaagcagctcacttctaaacaaatttttgtaattgatcactggctttgactcaaatccaggcaattgttgtaagagaactagaggtgtgatctgtatttgattctcatcaagaaggcatagtcttctatgattatttaaaaagtagcttatattccaagaggcttttagcaagctcctagagaagttataggaaatatggtaacaatttaaagatacagttacgtattttggaaaacagaacatgctgaaatggaaaggattgtttagcatccctacttttgtgactcaaggactcagaaactggattttcatctgcaacaagtatatacctgcagccacagaatacccaaaattgcttcagagatttttcatgagaaaactaattgaaagatcatctggtccaaccttttgtgggacagggagcctggatgagattaacaagctctctctgcagtcacatttgaaaacttcgggtgatggcagcaacaacttctctatctatcacttttctgttcttccatgcatcctgtcccaagtcctttcctttgcagtttctcccaaagcagcacttggactgcttccttccttttgatggtcagaagcttcctagatcaggtcctgccttttaatccagtccccaggagattttctgtccttgtggggaatatacttgctgttcactttctcctggtatttattacttttgtcttgtcaagttcagaaactctggcaaaagtggcagcagttaaattctgctgcaaaagctaagagctgaattttcaaatgtgtttttcagttcctgtggtggcattcagggtaccagaacagagtccttgggttcatttaatgcagtgcagctgttccttcagcgatctgaacccatctctttgtggctgttgctttgagccaacagtaacagccatgtccttaataaaaagtgccttgcttgccatgcatgtcataaagctcttcagcccctcaagcaacagtgaaatcaactgccatgattagaaagtgctaaaaaatcccctagctgtttgtgacctttccaaggagacagatctcctaaggtttctaagaatgggtaataaaacttgtttttctagctccagatgaaaaacaattctatttcaggatttctgtcatccagattaaataaaggactcca

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